Chemosensory signalling pathways involved in sensing of amino acids by the ghrelin cell.

abstract：:In the presence of a lateral periodic potential modulation, two-dimensional electrons may exhibit interesting phenomena, such as a graphene-like energy-momentum dispersion, Bloch oscillations, or the Hofstadter butterfly band structure. To create a sufficiently strong potential modulation using conventional semiconduc...

journal_title：Scientific reports

authors： Lu TM,Laroche D,Huang SH,Chuang Y,Li JY,Liu CW

更新日期：2016-02-11 00:00:00

abstract：:Recombinant human erythropoietin (rHuEPO) is a biopharmaceutical drug given to patients who have a low hemoglobin related to chronic kidney disease, cancer or anemia. However, some patients repeatedly receiving rHuEPO develop anti-rHuEPO neutralizing antibodies leading to the development of pure red cell aplasia (PRCA...

journal_title：Scientific reports

authors： Susantad T,Fuangthong M,Tharakaraman K,Tit-Oon P,Ruchirawat M,Sasisekharan R

更新日期：2021-01-15 00:00:00

abstract：:Family studies have identified a heritable component to self-harm that is partially independent from comorbid psychiatric disorders. However, the genetic aetiology of broad sense (non-suicidal and suicidal) self-harm has not been characterised on the molecular level. In addition, controversy exists about the degree to...

journal_title：Scientific reports

authors： Campos AI,Verweij KJH,Statham DJ,Madden PAF,Maciejewski DF,Davis KAS,John A,Hotopf M,Heath AC,Martin NG,Rentería ME

更新日期：2020-06-16 00:00:00

abstract：:Near-infrared up-conversion lasing in erbium(Er)-yttrium(Y) chloride silicate nanowires was demonstrated when pumped by 1476 nm laser at room temperature. The emission covers a very wide wavelength range (400-1000 nm). A clear threshold for 985 nm peak was observed at a launched average pump power of approximately 7 m...

journal_title：Scientific reports

authors： Ye R,Xu C,Wang X,Cui J,Zhou Z

更新日期：2016-10-05 00:00:00

abstract：:Anatase TiO2 is a typical photocatalyst, and its excellent performance is limited in ultraviolet light range due to its wide band gap of 3.2 eV. A series of Se-doped TiO2 nanoparticles in anatase structure with various Se concentrations up to 17.1 at.% were prepared using sol-gel method. The doped Se ions are confirme...

journal_title：Scientific reports

authors： Xie W,Li R,Xu Q

更新日期：2018-06-08 00:00:00

abstract：:Schizophrenia is a highly heritable disorder with multiple susceptibility genes. Previously, we identified CACNA1C rs2007044 as a new risk locus for schizophrenia, with the minor allele G as risk allele. This association was recently validated by a powerful genome-wide association study. However, the underlying neural...

journal_title：Scientific reports

authors： Zheng F,Cui Y,Yan H,Liu B,Jiang T

更新日期：2016-09-29 00:00:00

abstract：:Prestin in the lateral membrane of outer hair cells, is responsible for electromotility (EM) and a corresponding nonlinear capacitance (NLC). Prestin's voltage sensitivity is influenced by intracellular chloride. A regulator of intracellular chloride is a stretch-sensitive, non-selective conductance within the lateral...

journal_title：Scientific reports

authors： Bai JP,Moeini-Naghani I,Zhong S,Li FY,Bian S,Sigworth FJ,Santos-Sacchi J,Navaratnam D

更新日期：2017-04-19 00:00:00

abstract：:Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-ang...

journal_title：Scientific reports

authors： Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y

更新日期：2015-06-18 00:00:00

abstract：:Soils - constituting the largest terrestrial carbon pool - are vulnerable to climatic warming. Currently existing uncertainties regarding carbon fluxes within terrestrial systems can be addressed by studies of past carbon cycle dynamics and related climate change recorded in sedimentary successions. Here we show an ex...

journal_title：Scientific reports

authors： Pieńkowski G,Hodbod M,Ullmann CV

更新日期：2016-08-24 00:00:00

abstract：:Avoiding immune rejection after allogeneic induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) transplantation is a concern. However, mesenchymal stem cells (MSCs) can suppress immune rejection. To determine whether MSC co-transplantation can reduce immune rejection after allogeneic iPSC-CM transplantation, ...

journal_title：Scientific reports

authors： Yoshida S,Miyagawa S,Toyofuku T,Fukushima S,Kawamura T,Kawamura A,Kashiyama N,Nakamura Y,Toda K,Sawa Y

更新日期：2020-03-12 00:00:00

abstract：:The effect on post-operative outcomes after coronary artery bypass graft (CABG) surgery is not clear. Among 17,812 patients who underwent CABG during October 1,2006-September 28,2012 in any Department of US Veterans Affairs (VA) hospital, we identified 5,968 with available preoperative urine albumin-creatinine ratio (...

journal_title：Scientific reports

authors： George LK,Molnar MZ,Lu JL,Kalantar-Zadeh K,Koshy SK,Kovesdy CP

更新日期：2015-11-09 00:00:00

abstract：:Endoplasmic reticulum (ER) stress preconditioning protects cells against methylmercury (MeHg) cytotoxicity by inducing integrated stress responses such as eIF2α phosphorylation, ATF4 accumulation, and nonsense-mediated mRNA decay (NMD) suppression. Here we demonstrated that ER stress preconditioning results in the upr...

journal_title：Scientific reports

authors： Usuki F,Fujimura M,Yamashita A

更新日期：2017-09-28 00:00:00

abstract：:Although the rapid urease test (RUT) is a simple method for detecting Helicobacter pylori (H. pylori) infection, it requires sufficient biopsy samples and its sensitivity varies depending on the site and condition of H. pylori infection. We compared the diagnostic performance of a "sweeping method" for H. pylori detec...

journal_title：Scientific reports

authors： Noh CK,Lee GH,Park JW,Roh J,Han JH,Lee E,Park B,Lim SG,Shin SJ,Cheong JY,Kim JH,Lee KM

更新日期：2020-10-28 00:00:00

abstract：:Carbon is the most well-known black material in the history of man. Throughout the centuries, carbon has been used as a black material for paintings, camouflage, and optics. Although, the techniques to make other black surfaces have evolved and become more sophisticated with time, carbon still remains one of the best ...

journal_title：Scientific reports

authors： Shah A,Stenberg P,Karvonen L,Ali R,Honkanen S,Lipsanen H,Peyghambarian N,Kuittinen M,Svirko Y,Kaplas T

更新日期：2016-05-13 00:00:00

abstract：:Many studies have revealed the cognitive decline induced by microwave radiation. However, the systematic study on dose-dependent, frequency-dependent and accumulative effects of microwave exposure at different frequencies was lacking. Here, we studied the relationship between the effects and the power and frequency of...

journal_title：Scientific reports

authors： Tan S,Wang H,Xu X,Zhao L,Zhang J,Dong J,Yao B,Wang H,Zhou H,Gao Y,Peng R

更新日期：2017-09-07 00:00:00

abstract：:The competitive multi-armed bandit (CMAB) problem is related to social issues such as maximizing total social benefits while preserving equality among individuals by overcoming conflicts between individual decisions, which could seriously decrease social benefits. The study described herein provides experimental evide...

journal_title：Scientific reports

authors： Chauvet N,Jegouso D,Boulanger B,Saigo H,Okamura K,Hori H,Drezet A,Huant S,Bachelier G,Naruse M

更新日期：2019-08-22 00:00:00

abstract：:Complex societies are shaped by social relationships between multiple individuals. The pressure to track these relationships has driven the evolution of social cognition in primates. Importantly, it can be adaptive to track not only personal relationships, but also those established between third-parties. Primates hav...

journal_title：Scientific reports

authors： Whitehouse J,Meunier H

更新日期：2020-06-17 00:00:00

abstract：:The present study tested whether the LPS/TLR4 signal pathway in endometrial stromal cells is essential for the pathogenesis of adenomyosis. We tested the expression of TLR4, MD2 in the endometrium without adenomyosis (CE), the eutopic endometrium with adenomyosis (EuE) and the ectopic endometrium with adenomyosis (EE)...

journal_title：Scientific reports

authors： Guo J,Chen L,Luo N,Li C,Chen R,Qu X,Liu M,Kang L,Cheng Z

更新日期：2016-02-22 00:00:00

abstract：:One fundamental question in prey luring systems is to understand how visual signals are interpreted by the receiver. Predators lure prey by falsely imitating the signal of a model, or may exploit sensory preferences of the receivers, which search for rewarding signals. Crab spiders reflect ultraviolet (UV) light, ambu...

journal_title：Scientific reports

authors： Vieira C,Ramires EN,Vasconcellos-Neto J,Poppi RJ,Romero GQ

更新日期：2017-08-23 00:00:00

abstract：:Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, ...

journal_title：Scientific reports

authors： Dai M,Khan K,Zhang S,Jiang K,Zhang X,Wang W,Liang L,Cao H,Wang P,Wang P,Miao L,Qin H,Jiang J,Xue L,Chu J

更新日期：2016-06-14 00:00:00

abstract：:The aim of this study was to develop a novel method to detect circulating histones H3 and H2B in plasma based on multiple reaction monitoring targeted mass spectrometry and a multiple reaction monitoring approach (MRM-MS) for its clinical application in critical bacteriaemic septic shock patients. Plasma samples from ...

journal_title：Scientific reports

authors： García-Giménez JL,Romá-Mateo C,Carbonell N,Palacios L,Peiró-Chova L,García-López E,García-Simón M,Lahuerta R,Gimenez-Garzó C,Berenguer-Pascual E,Mora MI,Valero ML,Alpízar A,Corrales FJ,Blanquer J,Pallardó FV

更新日期：2017-09-06 00:00:00

abstract：:Drug addiction is a long-lasting disease characterized by compulsive drug intake mediated in part by neuronal and biological adaptations in key brain areas, such as the nucleus accumbens (NAc). While we previously demonstrated involvement of the activin 2a receptor in drug taking, the role of its ligand, activin A, in...

journal_title：Scientific reports

authors： Wang ZJ,Martin JA,Gancarz AM,Adank DN,Sim FJ,Dietz DM

更新日期：2017-03-08 00:00:00

abstract：:This study provides a pore-scale investigation of two-phase flow dynamics during primary drainage in a realistic heterogeneous rock sample. Using the lattice Boltzmann (LB) method, a series of three-dimensional (3D) immiscible displacement simulations are conducted and three typical flow patterns are identified and ma...

journal_title：Scientific reports

authors： Bakhshian S,Hosseini SA,Shokri N

更新日期：2019-03-04 00:00:00

abstract：:To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits. We iden...

journal_title：Scientific reports

authors： Polimanti R,Jensen KP,Gelernter J

更新日期：2017-04-21 00:00:00

abstract：:Polyphenol oxidases (PPOs) comprise tyrosinases (TYRs) and catechol oxidases (COs), which catalyse the initial reactions in the biosynthesis of melanin. TYRs hydroxylate monophenolic (monophenolase activity) and oxidize diphenolic (diphenolase activity) substrates, whereas COs react only with diphenols. In order to el...

journal_title：Scientific reports

authors： Panis F,Kampatsikas I,Bijelic A,Rompel A

更新日期：2020-02-03 00:00:00

abstract：:Mortuary practices in human evolution record cognitive, social changes and technological innovations. The Neolithic Revolution in the Levant was a watershed in this domain that has long fascinated the archaeological community. Plaster modelled skulls are well known at Jericho and several other Neolithic sites, and in ...

journal_title：Scientific reports

authors： Solazzo C,Courel B,Connan J,van Dongen BE,Barden H,Penkman K,Taylor S,Demarchi B,Adam P,Schaeffer P,Nissenbaum A,Bar-Yosef O,Buckley M

更新日期：2016-08-09 00:00:00

abstract：:Photoacoustic (optoacoustic) imaging can visualize vasculature deep in tissue using the high contrast of hemoglobin to light, with the high-resolution possible with ultrasound detection. Since angiogenesis, one of the hallmarks of cancer, leads to increased vascularity, photoacoustics holds promise in imaging breast c...

journal_title：Scientific reports

authors： Heijblom M,Piras D,Brinkhuis M,van Hespen JC,van den Engh FM,van der Schaaf M,Klaase JM,van Leeuwen TG,Steenbergen W,Manohar S

更新日期：2015-07-10 00:00:00

abstract：:Multishelled NiO hollow microspheres for high-performance supercapacitors have been prepared and the formation mechanism has been investigated. By using resin microspheres to absorb Ni(2+) and subsequent proper calcinations, the shell numbers, shell spacing and exterior shell structure were facilely controlled via var...

journal_title：Scientific reports

authors： Qi X,Zheng W,Li X,He G

更新日期：2016-09-12 00:00:00

abstract：:Noninvasive, safe and cost-effective cell viability assay is important in many fields of biological research such as cell culture and counting. We examined ten typical natural pigments extracted from food to find that Monascus pigment (MP) or anthocyanin pigment (AP: purple sweet potato and purple cabbage) with Tris (...

journal_title：Scientific reports

authors： Yamashita K,Tokunaga E

更新日期：2020-07-03 00:00:00

abstract：:Semi-arid ecosystems are key contributors to the global carbon cycle and may even dominate the inter-annual variability (IAV) and trends of the land carbon sink, driven largely by the El Niño-Southern Oscillation (ENSO). The linkages between dynamics of semi-arid ecosystems and climate at the hemispheric scale however...

journal_title：Scientific reports

authors： Zhang A,Jia G,Epstein HE,Xia J

更新日期：2017-02-09 00:00:00