Interstitial lung disease in 2015: where are we now?


BACKGROUND:Interstitial lung disease (ILD) includes a diverse group of respiratory conditions characterised by inflammation and fibrosis of the interstitium. Worsening hypoxia and respiratory failure may develop with disease progression. Disease behaviour and treatment responsiveness vary widely depending on the underlying aetiology. One of the most common types of ILD is idiopathic pulmonary fibrosis (IPF), which is associated with poor prognosis. OBJECTIVE:This article discusses recent advances in the field of ILD, including updated classification, diagnostic approach and break-through therapies. DISCUSSION:Establishing an accurate diagnosis in patients with ILD, ideally within a multidisciplinary team discussion, is critical for ensuring optimal outcomes. Recently, novel antifibrotic therapies have been shown to be effective in slowing disease progression in IPF, offering new hope for patients with the disease.


Aust Fam Physician


Troy L,Corte T


Has Abstract


2015-08-01 00:00:00










  • Structure of northern elephant seal population breeding on San Nicholas Island, California, in 1971.

    abstract::The structure of the population of northern elephant seals, Mirounga angustirostris, on San Nicolas Island, California, was studied during the 1970 and 1971 breeding season. At the population peak on 31 January 1971, there were 77 males, 306 females, 315 pups, and 6 yearlings on shore. The breeding population was subd...

    journal_title:Animal behaviour

    pub_type: 杂志文章


    authors: Odell DK

    更新日期:1977-02-01 00:00:00

  • Luteal phase support in ovarian induction cycles using human chorionic gonadotropin or oral progestagens.

    abstract:OBJECTIVE:To determine the efficacy of luteal phase support with human chorionic gonadotropin (hCG) or oral progesterone during human menopausal gonadotropin (hMG) ovulation induction. METHODS:Between September 1999 and March 2001, a total of 91 couples with infertility were recruited at Al-Hammadi Hospital, Riyadh, K...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Zayed FF,El-Jallad MF,Al-Chalabi HA

    更新日期:2003-01-01 00:00:00

  • Pest scenario of Spodoptera litura (Fab.) on groundnut under representative concentration pathways (RCPs) based climate change scenarios.

    abstract::Multi-model ensemble of Maximum (Tmax) and Minimum (Tmin) temperature data of four Representative Concentration Pathways viz., RCP 2.6, RCP 4.5, RCP 6.0 and RCP 8.5 of Coupled Model Intercomparison Project 5 (CMIP5) models were generated for ten major groundnut growing locations of the India to predict the number of g...

    journal_title:Journal of thermal biology

    pub_type: 杂志文章


    authors: Srinivasa Rao M,Rama Rao CA,Sreelakshmi P,Islam A,Subba Rao AVM,Ravindra Chary G,Bhaskar S

    更新日期:2020-12-01 00:00:00

  • In vitro and in vivo evaluation of ranitidine hydrochloride loaded hollow microspheres in rabbits.

    abstract::The objective of this investigation was to develop the hollow microspheres as a new dosage form of floating drug delivery systems with prolonged stomach retention time. Hollow microspheres containing ranitidine hydrochloride (RH) were prepared by a novel solvent diffusion-evaporation method using ethyl cellulose (EC) ...

    journal_title:Archives of pharmacal research

    pub_type: 杂志文章


    authors: Wei YM,Zhao L

    更新日期:2008-10-01 00:00:00

  • Sexually transmitted infections.

    abstract::It should be remembered that sexually transmitted infections may present with symptoms and signs not immediately referable to the genital tract. All practitioners should be aware of the changes in incidence and prevalence of these important infections. ...

    journal_title:Australian family physician

    pub_type: 杂志文章


    authors: Denham I

    更新日期:1989-04-01 00:00:00

  • Fighting with fire--how bushfire suppression can impact on fire fighters' health.

    abstract:BACKGROUND:Each year bushfire threatens Australia's rural, forest, and urban-rural areas. Australia's rural fire fighters work to curtail this threat in hot, smoky conditions, often at risk to their physical health. General practitioners, especially in rural areas, can help preserve the health of fire fighters during t...

    journal_title:Australian family physician

    pub_type: 杂志文章,评审


    authors: Aisbett B,Phillips M,Sargeant M,Gilbert B,Nichols D

    更新日期:2007-12-01 00:00:00

  • [Criteria on the legalization of abortion].

    abstract::We revised ethical concepts related to abortion from the points of view of the mothers; life, health, and considerations are made concerning the embryo or fetus as a biological, ontological, moral, and potential person. Certain religious matters on abortion are described and commented on. Effects of abortion penalizat...

    journal_title:Gaceta medica de Mexico

    pub_type: 杂志文章


    authors: García-Romero H,González-González A,Galicia J,Garcia-Barrios C

    更新日期:2000-05-01 00:00:00

  • The adherence-associated Fdp fasciclin I domain protein of the biohydrogen producer Rhodobacter sphaeroides is regulated by the global Prr pathway.

    abstract::Expression of fdp, encoding a fasciclin I domain protein important for adherence in the hydrogen-producing bacterium Rhodobacter sphaeroides, was investigated under a range of conditions to gain insights into optimization of adherence for immobilization strategies suitable for H2 production. The fdp promoter was linke...

    journal_title:International journal of hydrogen energy

    pub_type: 杂志文章


    authors: Jeong EL,Broad SJ,Moody RG,Phillips-Jones MK

    更新日期:2020-10-16 00:00:00

  • Treatment of acne vulgaris with 2% topical tea lotion.

    abstract:OBJECTIVE:To use 2% tea lotion as natural plant remedy in the treatment of acne vulgaris. METHODS:We conducted this study in the Department of Dermatology and Venereology in Baghdad Teaching Hospital, Iraq during the period between October 2002 and October 2004. In this single blind randomly controlled therapeutic stu...

    journal_title:Saudi medical journal

    pub_type: 杂志文章,随机对照试验


    authors: Sharquie KE,Al-Turfi IA,Al-Shimary WM

    更新日期:2006-01-01 00:00:00

  • Recurrent Kawasaki disease presenting as acute airway obstruction.

    abstract::Kawasaki disease is a common paediatric vasculitide. It is usually diagnosed by its classical constellation of mucocutaneous signs. Recurrent Kawasaki disease is a rare phenomenon that occurs in approximately 3% of all patients diagnosed with Kawasaki disease. Its presentation is usually similar to the first episode o...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: See XA,Prakash V,Tan KK

    更新日期:2012-12-01 00:00:00

  • Group 2 innate lymphoid cells exhibit progressively higher levels of activation during worsening of liver fibrosis.

    abstract:INTRODUCTION:The interleukin-33/interleukin-13 pathway is involved in the immunopathology of liver fibrosis and recently characterized group 2 innate lymphoid cells (ILC2) were identified as profibrotic immune cells in the liver of mouse models. Our aim was to elucidate whether ILC2 might be present in human liver tiss...

    journal_title:Annals of hepatology

    pub_type: 杂志文章


    authors: Gonzalez-Polo V,Pucci-Molineris M,Cervera V,Gambaro S,Yantorno SE,Descalzi V,Tiribelli C,Gondolesi GE,Meier D

    更新日期:2019-01-01 00:00:00

  • The prevalence of hypertension and its modifiable risk factors among lecturers of a medical school in Port Harcourt, south-south Nigeria: implications for control effort.

    abstract:BACKGROUND:Hypertension and other noncommunicable diseases are currently responsible for at least 20% of all deaths in Nigeria, and constitute up to 60% of the patients admitted into the medical wards of most tertiary hospitals in Nigeria. Yet, the treatment outcomes for the diseases have remained very poor, prompting ...

    journal_title:Nigerian journal of clinical practice

    pub_type: 杂志文章


    authors: Ordinioha B

    更新日期:2013-01-01 00:00:00

  • [Intra-operative myelography in treatment of fractures of thoracolumbar spine].

    abstract:PURPOSE OF THE STUDY:The aim of this retrospective study was to evaluate the results of intra-operative myelography as the method used to assess the reduction of bone fragments from the posterior margin of the vertebral body. MATERIAL AND METHODS:Forty patients with 42 comminuted fractures of the thoracolumbar spine w...

    journal_title:Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca

    pub_type: 杂志文章


    authors: Tomčovčík L,Cuha R,Raši R

    更新日期:2010-08-01 00:00:00

  • High and Low Cognitive Risk For Depression: Stability From Late Adolescence to Early Adulthood.

    abstract::Negative cognitive styles are an important cognitive vulnerability for depression, but stability of high cognitive risk, once developed, is unclear. The current study examined stability of cognitive vulnerability to depression in individuals at high and low cognitive risk (extreme scores on both the CSQ and DAS) over ...

    journal_title:Cognitive therapy and research

    pub_type: 杂志文章


    authors: Romens SE,Abramson LY,Alloy LB

    更新日期:2009-01-01 00:00:00

  • [Longitudinal study of health related quality of life in multiple sclerosis: correlation with MRI parameters].

    abstract:INTRODUCTION:Health related quality of life (HRQOL) is often affected in multiple sclerosis (MS). Nevertheless, to our knowledge, there is no longitudinal study in the literature about the correlation between MRI parameters and HRQOL in MS patients. METHODS:We included 28 patients with clinically definite relapsing re...

    journal_title:Revue neurologique

    pub_type: 杂志文章


    authors: Cohen M,Lebrun C,Aufauvre D,Chanalet S,Filleau-Bertogliatti C,Camu W,Thomas P,Malandain G,Clavelou P

    更新日期:2010-11-01 00:00:00

  • Phenotypic and genotypic diversity of airborne fungal spores in Demänovská Ice Cave (Low Tatras, Slovakia).

    abstract::This paper is the first aero-mycological report from Demänovská Ice Cave. Fungal spores were sampled from the internal and external air of the cave in June, 2014, using the impact method with a microbiological air sampler. Airborne fungi cultured on PDA medium were identified using a combination of classical phenotypi...


    pub_type: 杂志文章


    authors: Ogórek R,Kozak B,Višňovská Z,Tančinová D

    更新日期:2018-01-01 00:00:00

  • In vivo antimalarial activities of ethanolic crude extracts and fractions of leaf and root of Carpolobia lutea.

    abstract::Carpolobia lutea (leaves and root) is used traditionally as malarial remedy by the Ibibios of Niger Delta of Nigeria and Benin. This study was aimed to investigate the antiplasmodial potentials of the crude leaf and root extracts of this plant as well as their fractions in vivo in Plasmodium berghei berghei-infected m...

    journal_title:Pakistan journal of pharmaceutical sciences

    pub_type: 杂志文章


    authors: Okokon JE,Effiong IA,Ettebong E

    更新日期:2011-01-01 00:00:00

  • A new method for experimental simulation of EMG using multi-channel independent stimulation of small groups of motor units.

    abstract::The experimental simulation method was based upon the separate activation of up to 10 small groups of motor units (MU) in an acute nerve-muscle preparation. The investigator was able to precisely control and systematically alter the features of MU pool activation strategies. No implicit assumptions were made regarding...

    journal_title:Motor control

    pub_type: 杂志文章


    authors: Hulliger M,Day SJ,Guimares A,Herzog W,Zhang YT

    更新日期:2001-01-01 00:00:00

  • Shear bond strength of resin composite to enamel and dentin submitted to a carbamide peroxide dentifrice.

    abstract:PURPOSE:To assess the shear bond strength of resin composite to human enamel and dentin after using a whitening dentifrice containing carbamide peroxide for 21 days. METHODS:Thirty enamel and 30 dentin slabs were embedded, flattened and randomly divided into three groups (n=10) that received different treatments: carb...

    journal_title:American journal of dentistry

    pub_type: 杂志文章,随机对照试验


    authors: da Silva BM,Flório FM,Basting RT

    更新日期:2007-10-01 00:00:00

  • Renal colic and recurrent urinary calculi. Management and prevention.

    abstract:BACKGROUND:Urinary calculi are a relatively common problem and up to 80% of patients with calculi who are untreated will experience one or more recurrences within five years. OBJECTIVE:This paper outlines the causes of urinary calculi and presents evidence for the less conventional treatment of renal colic with NSAIDs...

    journal_title:Australian family physician

    pub_type: 杂志文章,评审


    authors: Laerum E,Murtagh J

    更新日期:2001-01-01 00:00:00

  • Immunochemotherapy with levamisole for stage III gastric cancer patients.

    abstract::Levamisole (LMS) was given to stage III gastric cancer patients starting three days before gastrectomy, at a does of 150 mg/day for three consecutive days every other week. Survival rates of these patients were compared with those of stage III gastric cancer patients previously operated in our Department who had not r...

    journal_title:Acta medica Okayama

    pub_type: 杂志文章


    authors: Miwa H,Orita K

    更新日期:1983-12-01 00:00:00

  • [Blood culture positivity: is it pathogen or contaminant?].

    abstract::Blood culture is the gold standard for diagnosis of bloodstream infections. Many studies have shown that rapid isolation and identification of the microorganisms in blood culture and initiation of early antimicrobial therapy are critically important to reduce the mortality rate. It was found that the rate of contamina...

    journal_title:Mikrobiyoloji bulteni

    pub_type: 杂志文章


    authors: Balıkçı A,Belas Z,Eren Topkaya A

    更新日期:2013-01-01 00:00:00

  • Acute low back pain: assessment and management.

    abstract:BACKGROUND:Back pain is a common presenting problem in Australian general practice. Serious causes, however, are rare. Tumours, infections and fractures account for less than 1% of cases and can usually can be recognised or excluded by taking a careful history. Patients should expect a good outcome. OBJECTIVE:This art...

    journal_title:Australian family physician

    pub_type: 杂志文章,评审


    authors: Wilk V

    更新日期:2004-06-01 00:00:00

  • Psychosocial aspects of repeat abortions in Singapore--a preliminary report.

    abstract::The rate of repeat abortions in Singapore has risen from 10% of all abortions in 1975 to 42% in 1982. This study sought to identify psychosocial characteristics of 100 Chinese women 15-44 years of age who requested a repeat abortion; 100 antenatal patients and 100 1st-time abortees, matched with subjects for age and ...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Tsoi WF,Ratnam SS,Tay GE

    更新日期:1984-04-01 00:00:00

  • [Dermatologists facing the risk of viral transmission. Analysis of the precautionary measures of 472 practitioners].

    abstract::On the occasion of the "Journées Dermatologiques de Paris", in March 1988 we designed a survey to evaluate the sterile practices of French dermatologists in the "AIDS era". During the two days meeting, attended by 2,584 participants, 472 questionnaire forms were filled in (answer rate 18.5 p. 100). Among responders 43...

    journal_title:Annales de dermatologie et de venereologie

    pub_type: 杂志文章,评审


    authors: Caumes E,Baspeyras M,Touraine R,Roujeau JC

    更新日期:1990-01-01 00:00:00

  • [Peripheral neuropathies in human immunodeficiency virus infection. A prospective study of 56 patients].

    abstract::Neurologic disorders are common in patients infected with HIV1. Judging from reported cases, the central nervous system would be more frequently involved than the peripheral nervous system (PNS). The purpose of the present prospective study was to ascertain the incidence and the nature of PNS disorders in patients inf...

    journal_title:Revue neurologique

    pub_type: 杂志文章


    authors: Gastaut JL,Gastaut JA,Pellissier JF,Tapko JB,Weill O

    更新日期:1989-01-01 00:00:00

  • Leo Kanner: his years in Berlin, 1906-24. The roots of autistic disorder.

    abstract::By providing the first description of infantile autism Leo Kanner (1894-1981) has substantially influenced the field of child and adolescent psychiatry. The classification of the disorder seems to be evolving with progress in clinical and diagnostic research, epidemiology and genetics. In the current classification sy...

    journal_title:History of psychiatry

    pub_type: 传,历史文章,杂志文章


    authors: Neumärker KJ

    更新日期:2003-06-01 00:00:00

  • Fecundity above the Species Level: Ovule Number and Brood Size in the Genisteae (Fabaceae: Papilionoideae).

    abstract::Per-fruit components of fecundity (ovules per ovary, seeds per fruit, seed : ovule ratio, and patterns of seed maturation within pods) were studied in 33 species of the Genisteae, a legume tribe of mostly Mediterranean shrubs, e.g., Cytisus, Ulex, that also includes more widespread herbs such as Lupinus. Species ident...

    journal_title:International journal of plant sciences

    pub_type: 杂志文章


    authors: Herrera J

    更新日期:1999-09-01 00:00:00

  • Chemical pollution assessment and prioritisation model for the Upper and Middle Vaal water management areas of South Africa.

    abstract::A chemical pollution assessment and prioritisation model was developed for the Upper and Middle Vaal water management areas of South Africa in order to provide a simple and practical Pollution Index to assist with mitigation and rehabilitation activities. Historical data for 2003 to 2008 from 21 river sites were cubic...

    journal_title:Journal of water and health

    pub_type: 杂志文章


    authors: Dzwairo B,Otieno FA

    更新日期:2014-12-01 00:00:00

  • Association between self-rated health and incident severe hypertension among men: a population-based cohort study.

    abstract:INTRODUCTION:Self-rated health (SRH) is a consistent predictor of cardiovascular disease and mortality. However, the intermediate biological mechanisms behind this association are not clear. We examined the longitudinal relationship between SRH and incident severe hypertension. METHODS:We studied a population-based co...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Shankar A,Wang JJ,Rochtchina E,Mitchell P

    更新日期:2008-11-01 00:00:00