Small island, big genetic discoveries.

Abstract:

:Three new studies have identified new genes and sequence variants implicated in blood lipids, inflammatory markers, hemoglobin levels and adult height variation in Sardinia. These reports highlight the usefulness of large-scale genotype imputation based on whole-genome sequencing, particularly in isolated populations, in studying the genetics of complex human phenotypes.

journal_name

Nat Genet

journal_title

Nature genetics

authors

Lettre G,Hirschhorn JN

doi

10.1038/ng.3426

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

1224-5

issue

11

eissn

1061-4036

issn

1546-1718

pii

ng.3426

journal_volume

47

pub_type

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