Prevalence, Comorbidities, and Risk of Perioperative Complications in Human Immunodeficiency Virus-Positive Patients Undergoing Cervical Spine Surgery.


STUDY DESIGN:Retrospective database analysis. OBJECTIVE:To evaluate outcomes of human immunodeficiency virus (HIV) positive patients after cervical spine surgery. SUMMARY OF BACKGROUND DATA:Highly active antiretroviral medications have qualitatively altered the natural history of HIV, thus increasing the number of HIV-positive patients seeking treatment for chronic degenerative conditions. Minimal data exist on HIV patients undergoing degenerative cervical spine surgery. METHODS:The Nationwide Inpatient Sample was examined from 2002 to 2011. Hospitalizations were identified using International Classification of Diseases Ninth Revision, Clinical Modification (ICD-9-CM) procedural codes for cervical spine surgery and diagnoses codes for degenerative conditions of the cervical spine, and HIV. Statistical analysis was conducted to evaluate associations between HIV status and perioperative complications. RESULTS:A total of 1,602,129 patients underwent degenerative cervical spine surgery, of which 3700 patients (0.23%) had HIV. The prevalence of HIV increased over the study period from 0.19% to 0.33% (P < 0.001). Patients with HIV were younger (48.6 yrs vs. 53.4 yrs, P < 0.001) and more likely to be male (P < 0.001). HIV patients had significantly greater odds of having chronic pulmonary disease, liver disease, and drug abuse. Unadjusted analysis did not reveal increased rate of acute complications among HIV-positive patients compared with negative controls (3.8% vs. 3.7%, P = 0.62). Multivariate analysis did not identify HIV as a significant predictor of complication (odds ratio = 1.04, P = 0.84). HIV was associated with a 1.5 day increased length of stay AND 1.29 fold increase in median costs compared with controls ($14,551 vs. 18,846, P < 0.001). CONCLUSION:The prevalence of HIV patients undergoing degenerative cervical spine surgery is increasing. A diagnosis of HIV was not associated with an increased risk of perioperative complication among patients undergoing degenerative cervical spine surgery. Further clinical studies are needed to evaluate predictors of complications among HIV patients and long-term outcomes. LEVEL OF EVIDENCE:4.


Spine (Phila Pa 1976)




Lovy AJ,Guzman JZ,Skovrlj B,Cho SK,Hecht AC,Qureshi SA




Has Abstract


2015-11-01 00:00:00
















  • Discography and magnetic resonance imaging in the diagnosis of lumbar disc disruption.

    abstract::Four cases of patients with normal magnetic resonance (MR) studies of the lumbar spine and abnormal discography are presented to illustrate that normal lumbar disc signal intensity does not necessarily rule out disc degeneration. ...


    pub_type: 杂志文章


    authors: Kornberg M

    更新日期:1989-12-01 00:00:00

  • Prophylactic stabilization of vertebral body metastasis at risk of imminent fracture using balloon kyphoplasty.

    abstract:STUDY DESIGN:Case report. OBJECTIVE:Presentation of the previously unreported technique of balloon kyphoplasty being used to prophylactically stabilize a vertebral body metastasis at risk of imminent fracture. SUMMARY OF BACKGROUND DATA:Many patients with spinal metastases are not suitable for a total en bloc resecti...


    pub_type: 杂志文章


    authors: Langdon J,Bernard J,Molloy S

    更新日期:2009-06-01 00:00:00

  • Differences in the work-up and treatment of conditions associated with low back pain by patient gender and ethnic background.

    abstract:STUDY DESIGN:Retrospective review comparing physician workup of degenerative lumbosacral pathologies between different genders and ethnic groups. OBJECTIVES:To investigate whether patient ethnicity and gender influence the workup and treatment of degenerative spinal pathologies. SUMMARY OF BACKGROUND DATA:Data from n...


    pub_type: 杂志文章,多中心研究


    authors: Taylor BA,Casas-Ganem J,Vaccaro AR,Hilibrand AS,Hanscom BS,Albert TJ

    更新日期:2005-02-01 00:00:00

  • Usefulness of electromyography compared to computed tomography scans in pedicle screw placement.

    abstract:STUDY DESIGN:This is a retrospective analysis of 30 pediatric deformity surgeries. OBJECTIVE:The purpose of this study was to evaluate the accuracy of neuromonitoring in comparison to postoperative computed tomography scans for pedicle screw position. SUMMARY OF BACKGROUND DATA:Triggered electromyography potentials i...


    pub_type: 杂志文章


    authors: Duffy MF,Phillips JH,Knapp DR,Herrera-Soto JA

    更新日期:2010-01-15 00:00:00

  • Commonly adopted postures and their effect on the lumbar spine.

    abstract::The activity of the erector spinae muscles and the changes in lumbar curvature were measured in 11 subjects in a range of commonly adopted postures to see if there were any consistent trends. Surface electrodes were used to measure back muscle activity and lumbar curvature was measured using electronic inclinometers. ...


    pub_type: 杂志文章


    authors: Dolan P,Adams MA,Hutton WC

    更新日期:1988-02-01 00:00:00

  • Surgery for lumbar spinal stenosis. Attempted meta-analysis of the literature.

    abstract::A meta-analysis was undertaken to determine the effects of surgery for lumbar spinal stenosis on pain and disability. Seventy-four journal articles met inclusion criteria and were independently reviewed by two readers. On average, 64% of patients treated surgically for lumbar spinal stenosis were reported to have good...


    pub_type: 杂志文章,meta分析


    authors: Turner JA,Ersek M,Herron L,Deyo R

    更新日期:1992-01-01 00:00:00

  • Anterior cervical screw extrusion leading to acute upper airway obstruction: case report.

    abstract:STUDY DESIGN:Case report of late postoperative complication. SUMMARY OF BACKGROUND DATA:There have been a number of reports of migration and extrusion of cervical fusion instrumentation. The majority of such cases have a benign outcome. To our knowledge, cervical instrumentation extrusion resulting in prevertebral abs...


    pub_type: 杂志文章


    authors: Wong DT,Fehlings MG,Massicotte EM

    更新日期:2005-11-15 00:00:00

  • Validity and reproducibility of self-report measures of walking capacity in lumbar spinal stenosis.

    abstract:STUDY DESIGN:Measurement (validity) study. OBJECTIVE:Examine validity and reproducibility of self-report measures of walking capacity for use in patients with lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA:Treatment outcomes in patients with LSS are often determined using data from self-report questionnaire...


    pub_type: 杂志文章


    authors: Tomkins-Lane CC,Battié MC

    更新日期:2010-11-01 00:00:00

  • Sagittal Alignment Profile Following Selective Thoracolumbar/Lumbar Fusion in Patients With Lenke Type 5C Adolescent Idiopathic Scoliosis.

    abstract:STUDY DESIGN:A retrospective case series. OBJECTIVE:This study aimed to report the sagittal outcome measures in patients with Lenke type 5C adolescent idiopathic scoliosis (AIS) undergoing thoracolumbar/lumbar (TL/L) fusion surgery. SUMMARY OF BACKGROUND DATA:Previous studies have demonstrated coronal correction of L...


    pub_type: 杂志文章


    authors: Tauchi R,Kawakami N,Ohara T,Saito T,Tanabe H,Morishita K,Yamauchi I

    更新日期:2019-09-01 00:00:00

  • Dual Time-Point 18F-FDG PET/CT in Spinal Sarcoidosis: A Single Institution Case Series.

    abstract:STUDY DESIGN:A case series of dual time-point F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of spinal cord sarcoidosis. OBJECTIVE:The aim of this study was to illustrate three cases of spinal sarcoidosis with occult presentation and subsequent identificati...


    pub_type: 杂志文章


    authors: Ordóñez-Rubiano EG,Solano-Noguera DF,Row W,Weinberg J,Tatsui CE,Johnson JM,Gule-Monroe MK

    更新日期:2019-11-01 00:00:00

  • Surgical treatment of vertebral osteomyelitis with recombinant human bone morphogenetic protein-2.

    abstract:STUDY DESIGN:A retrospective clinical study. OBJECTIVE:To evaluate the use of recombinant human bone morphogenetic protein-2 (rhBMP-2) as the primary graft material for the surgical treatment of vertebral osteomyelitis. SUMMARY OF BACKGROUND DATA:The clinical and radiographic results using allograft, autograft, and v...


    pub_type: 杂志文章,多中心研究


    authors: O'Shaughnessy BA,Kuklo TR,Ondra SL

    更新日期:2008-03-01 00:00:00

  • Anatomical and pathological considerations in percutaneous vertebroplasty and kyphoplasty: a reappraisal of the vertebral venous system.

    abstract:OBJECTIVES:To focus attention of the clinician on the anatomy and (patho)physiology of the vertebral venous system, so as to offer a tool to better understand and anticipate (potential) complications that are related to the application of percutaneous vertebroplasty and kyphoplasty. BACKGROUND:Percutaneous vertebropla...


    pub_type: 杂志文章,评审


    authors: Groen RJ,du Toit DF,Phillips FM,Hoogland PV,Kuizenga K,Coppes MH,Muller CJ,Grobbelaar M,Mattyssen J

    更新日期:2004-07-01 00:00:00

  • Automated percutaneous discectomy.

    abstract::Automated percutaneous discectomy is a new, safe procedure for treating herniated lumbar discs still contained by the annulus or posterior longitudinal ligament. In 1985, one of the authors reported a percutaneous nucleus aspiration technique using a 2-mm aspiration probe. This small probe produced minimal tissue dama...


    pub_type: 杂志文章


    authors: Davis GW,Onik G,Helms C

    更新日期:1991-03-01 00:00:00

  • Accuracy of magnetic resonance imaging signal intensity ratio measurements in the evaluation of multifidus muscle injury and atrophy relative to that of histological examinations.

    abstract:STUDY DESIGN:A matched-pairs animal study. OBJECTIVE:To confirm the accuracy of magnetic resonance imaging (MRI) as a means of evaluating edema and fat degeneration of the multifidus muscle by comparing measurements made using MRI with those made using histological examination. SUMMARY OF BACKGROUND DATA:MRI is consi...


    pub_type: 杂志文章


    authors: Zhi-Jun H,Wen-Bin X,Shuai C,Zhi-Jie Z,Feng-Dong Z,Xiao-Jing Y,Ji-Ying W,Li-Li H,Feng J,Guo-Xiang F,Dan-Ju W,Shun-Wu F,Xiang-Qian F

    更新日期:2014-05-01 00:00:00

  • Decompression Surgery Alone Versus Decompression Plus Fusion in Symptomatic Lumbar Spinal Stenosis: A Swiss Prospective Multicenter Cohort Study With 3 Years of Follow-up.

    abstract:STUDY DESIGN:Retrospective analysis of a prospective, multicenter cohort study. OBJECTIVE:To estimate the added effect of surgical fusion as compared to decompression surgery alone in symptomatic lumbar spinal stenosis patients with spondylolisthesis. SUMMARY OF BACKGROUND DATA:The optimal surgical management of lumb...


    pub_type: 杂志文章,多中心研究


    authors: Ulrich NH,Burgstaller JM,Pichierri G,Wertli MM,Farshad M,Porchet F,Steurer J,Held U,LSOS Study Group.

    更新日期:2017-09-15 00:00:00

  • Reliability and validity of lumbosacral spine radiograph reading by chiropractors, chiropractic radiologists, and medical radiologists.

    abstract:STUDY DESIGN:A cross-sectional diagnostic study was conducted in two sessions. OBJECTIVE:To determine and compare the reliability and validity of contraindications to chiropractic treatment (infections, malignancies, inflammatory spondylitis, and spondylolysis-listhesis) detected by chiropractors, chiropractic radiolo...


    pub_type: 杂志文章


    authors: de Zoete A,Assendelft WJ,Algra PR,Oberman WR,Vanderschueren GM,Bezemer PD

    更新日期:2002-09-01 00:00:00

  • Surgical anatomy of the vertebral arteries.

    abstract:STUDY DESIGN:This study compared direct measurements of the distances between the vertebral arteries in the cervical spines of human cadaver specimens with data obtained from axial computed tomography images of these specimens. OBJECTIVE:To determine whether the information obtained from a computed tomography scan can...


    pub_type: 杂志文章


    authors: Heary RF,Albert TJ,Ludwig SC,Vaccaro AR,Wolansky LJ,Leddy TP,Schmidt RR

    更新日期:1996-09-15 00:00:00

  • Automatic localization of target vertebrae in spine surgery: clinical evaluation of the LevelCheck registration algorithm.

    abstract:STUDY DESIGN:A 3-dimensional-2-dimensional (3D-2D) image registration algorithm, "LevelCheck," was used to automatically label vertebrae in intraoperative mobile radiographs obtained during spine surgery. Accuracy, computation time, and potential failure modes were evaluated in a retrospective study of 20 patients. OB...


    pub_type: 杂志文章


    authors: Lo SF,Otake Y,Puvanesarajah V,Wang AS,Uneri A,De Silva T,Vogt S,Kleinszig G,Elder BD,Goodwin CR,Kosztowski TA,Liauw JA,Groves M,Bydon A,Sciubba DM,Witham TF,Wolinsky JP,Aygun N,Gokaslan ZL,Siewerdsen JH

    更新日期:2015-04-15 00:00:00

  • Treatment of unstable thoracolumbar and lumbar spine injuries using Cotrel-Dubousset instrumentation.

    abstract:STUDY DESIGN:In this prospective study, the results of treating unstable thoracolumbar and lumbar injuries with Cotrel-Dubousset instrumentation were investigated. OBJECTIVE:To determine the pain and work status of the patients, to evaluate neurologic status, and to assess the efficacy of instrumentation in the short ...


    pub_type: 杂志文章


    authors: Katonis PG,Kontakis GM,Loupasis GA,Aligizakis AC,Christoforakis JI,Velivassakis EG

    更新日期:1999-11-15 00:00:00

  • 2000 Young Investigator Research Award winner. Evaluation of OP-1 as a graft substitute for intertransverse process lumbar fusion.

    abstract:STUDY DESIGN:An established rabbit intertransverse process lumbar fusion model was used to evaluate osteogenic protein (OP)-1 as a potential graft substitute. OBJECTIVES:To determine whether OP-1 is effective in producing intertransverse process lumbar fusion in a rabbit model. SUMMARY OF BACKGROUND DATA:Autogenous i...


    pub_type: 杂志文章


    authors: Grauer JN,Patel TC,Erulkar JS,Troiano NW,Panjabi MM,Friedlaender GE

    更新日期:2001-01-15 00:00:00

  • Does plate fixation prevent disc degeneration after a lateral anulus tear?

    abstract:STUDY DESIGN:The sheep model was used to investigate the development of disc degeneration after outer anular tearing. OBJECTIVES:The authors determined whether plate fixation promotes healing of peripheral anular tears and thereby minimizes disc degeneration. SUMMARY OF BACKGROUND DATA:A limited outer anular tear (si...


    pub_type: 杂志文章


    authors: Moore RJ,Latham JM,Vernon-Roberts B,Fraser RD

    更新日期:1994-12-15 00:00:00

  • Rosai-Dorman disease causing cervical myelopathy.

    abstract:STUDY DESIGN:A case report of a rare disease entity and review of the literature. OBJECTIVES:To illustrate the occurrence of an unusual disease affecting the spine and spinal canal. SUMMARY OF BACKGROUND DATA:Rosai-Dorman disease is considered an idiopathic benign lymphoproliferative disease that typically occurs in ...


    pub_type: 杂志文章,评审


    authors: Hollowell JP,Wolfla CE,Shah NC,Mark LP,Whittaker MH

    更新日期:2000-06-01 00:00:00

  • "July Effect" Revisited: July Surgeries at Residency Training Programs are Associated with Equivalent Long-term Clinical Outcomes Following Lumbar Spondylolisthesis Surgery.

    abstract:STUDY DESIGN:Retrospective analysis of a prospective registry. OBJECTIVE:We utilized the Quality Outcomes Database (QOD) registry to investigate the "July Effect" at QOD spondylolisthesis module sites with residency trainees. SUMMARY OF BACKGROUND DATA:There is a paucity of investigation on the long-term outcomes fol...


    pub_type: 杂志文章


    authors: Chan AK,Patel A,Bisson EF,Bydon M,Glassman SD,Foley KT,Shaffrey CI,Potts EA,Shaffrey ME,Coric D,Knightly JJ,Park P,Wang MY,Fu KM,Slotkin JR,Asher AL,Virk MS,Kerezoudis P,Alvi MA,Guan J,Choy W,Haid RW,Mummaneni

    更新日期:2020-12-24 00:00:00

  • Progression of vertebral wedging in an asymmetrically loaded rat tail model.

    abstract:STUDY DESIGN:A rat tail model was used to test the hypothesis that angulation and asymmetric axial compressive loading would lead to vertebral wedging because of asymmetric longitudinal growth in the physes. OBJECTIVES:To study the effect of angulation and asymmetric loading on the progression of spinal curvature in a...


    pub_type: 杂志文章


    authors: Mente PL,Stokes IA,Spence H,Aronsson DD

    更新日期:1997-06-15 00:00:00

  • Studies in the modified Scoliosis Research Society Outcomes Instrument in adults: validation, reliability, and discriminatory capacity.

    abstract:STUDY DESIGN:Observational study of patients with scoliosis and matched controls. OBJECTIVES:To determine the validity and reliability of the modified Scoliosis Research Society Outcomes Instrument (SRS-22) for use in the assessment of deformity in adults. To demonstrate the discriminate validity of the SRS-22 in diff...


    pub_type: 杂志文章


    authors: Berven S,Deviren V,Demir-Deviren S,Hu SS,Bradford DS

    更新日期:2003-09-15 00:00:00

  • Posterior extensive simultaneous multisegment decompression with posterolateral fusion for cervical myelopathy with cervical instability and kyphotic and/or S-shaped deformities.

    abstract::From June 1978 to May 1988, posterior decompression with posterolateral fusion was performed at Tenri Hospital on 63 cases of cervical myelopathy with instability and/or malalignment including kyphotic and/or S-shaped deformities. Among 46 cases followed up for more than 1 year, 41 cases (89.1%) improved; 21 cases (45...


    pub_type: 杂志文章


    authors: Miyazaki K,Tada K,Matsuda Y,Okuno M,Yasuda T,Murakami H

    更新日期:1989-11-01 00:00:00

  • Histological study of chordoma origin from fetal notochordal cell rests.

    abstract:STUDY DESIGN:The histological comparative study was performed on chordoma and notochordal cell rests (NCRs). OBJECTIVE:To understand the histological similarity and homology of chordoma and NCRs, further supplying direct evidence of chordoma origin from NCRs. SUMMARY OF BACKGROUND DATA:Although many studies supported...


    pub_type: 杂志文章


    authors: Shen J,Shi Q,Lu J,Wang DL,Zou TM,Yang HL,Zhu GQ

    更新日期:2013-12-01 00:00:00

  • Does Sacral Slanting Affect Distal Adding-on in Lenke Type 1A Adolescent Idiopathic Scoliosis?

    abstract:STUDY DESIGN:A retrospective clinical study. OBJECTIVE:The purpose of this study was to identify risk factors for postoperative distal adding-on in Lenke 1A adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA:Distal adding-on is a postoperative complication associated with the Lenke type 1A curve. Although va...


    pub_type: 杂志文章


    authors: Joo YS,Hwang CJ,Cho JH,Baik JM,Cho NI,Lee DH,Lee MY,Yoon SJ,Lee CS

    更新日期:2018-09-01 00:00:00

  • Changes in bone mineral density in the intertransverse fusion mass after instrumented single-level lumbar fusion: a prospective 1-year follow-up.

    abstract:STUDY DESIGN:Prospective cohort. OBJECTIVE:The purpose of this study was to evaluate changes in bone mineral density (BMD) in the intertransverse fusion mass as representative for the process of bone remodeling after spinal fusion. SUMMARY OF BACKGROUND DATA:Intertransverse bone graft is frequently applied to facilit...


    pub_type: 杂志文章


    authors: Hagenmaier F,Kok D,Hol A,Rijnders T,Oner FC,van Susante JL

    更新日期:2013-04-15 00:00:00

  • Outpatient lumbar myelography. Analysis of complications after myelography comparing outpatients with inpatients.

    abstract::Over a 2-year period, 92 patients were submitted as outpatients to lumbar myelography using lopamidol, a new nonionic water-soluble contrast medium. The incidence and severity of adverse reactions associated with myelography in these cases were compared with those in 116 patients who underwent lopamidol myelography as...


    pub_type: 杂志文章


    authors: Postacchini F,Massobrio M

    更新日期:1985-07-01 00:00:00