Prevalence, Comorbidities, and Risk of Perioperative Complications in Human Immunodeficiency Virus-Positive Patients Undergoing Cervical Spine Surgery.


STUDY DESIGN:Retrospective database analysis. OBJECTIVE:To evaluate outcomes of human immunodeficiency virus (HIV) positive patients after cervical spine surgery. SUMMARY OF BACKGROUND DATA:Highly active antiretroviral medications have qualitatively altered the natural history of HIV, thus increasing the number of HIV-positive patients seeking treatment for chronic degenerative conditions. Minimal data exist on HIV patients undergoing degenerative cervical spine surgery. METHODS:The Nationwide Inpatient Sample was examined from 2002 to 2011. Hospitalizations were identified using International Classification of Diseases Ninth Revision, Clinical Modification (ICD-9-CM) procedural codes for cervical spine surgery and diagnoses codes for degenerative conditions of the cervical spine, and HIV. Statistical analysis was conducted to evaluate associations between HIV status and perioperative complications. RESULTS:A total of 1,602,129 patients underwent degenerative cervical spine surgery, of which 3700 patients (0.23%) had HIV. The prevalence of HIV increased over the study period from 0.19% to 0.33% (P < 0.001). Patients with HIV were younger (48.6 yrs vs. 53.4 yrs, P < 0.001) and more likely to be male (P < 0.001). HIV patients had significantly greater odds of having chronic pulmonary disease, liver disease, and drug abuse. Unadjusted analysis did not reveal increased rate of acute complications among HIV-positive patients compared with negative controls (3.8% vs. 3.7%, P = 0.62). Multivariate analysis did not identify HIV as a significant predictor of complication (odds ratio = 1.04, P = 0.84). HIV was associated with a 1.5 day increased length of stay AND 1.29 fold increase in median costs compared with controls ($14,551 vs. 18,846, P < 0.001). CONCLUSION:The prevalence of HIV patients undergoing degenerative cervical spine surgery is increasing. A diagnosis of HIV was not associated with an increased risk of perioperative complication among patients undergoing degenerative cervical spine surgery. Further clinical studies are needed to evaluate predictors of complications among HIV patients and long-term outcomes. LEVEL OF EVIDENCE:4.


Spine (Phila Pa 1976)




Lovy AJ,Guzman JZ,Skovrlj B,Cho SK,Hecht AC,Qureshi SA




Has Abstract


2015-11-01 00:00:00
















  • The effect of soft-tissue restraints after type II odontoid fractures in the elderly: a biomechanical study.

    abstract:STUDY DESIGN:A biomechanical analysis of soft-tissue restraints to passive motion in odontoid fractures. OBJECTIVE:To quantify the role of the C1-C2 facet joint capsules and anterior longitudinal ligaments (ALLs) in the setting of a type II odontoid fracture in the elderly. SUMMARY OF BACKGROUND DATA:The odontoid pro...


    pub_type: 杂志文章


    authors: McCabe CM,McLachlin SD,Bailey SI,Gurr KR,Bailey CS,Dunning CE

    更新日期:2012-05-20 00:00:00

  • Radicular pain after vertebroplasty: compression or irritation of the nerve root? Initial experience with the "cooling system".

    abstract:STUDY DESIGN:During vertebroplasty (VP), polymethylmethacrylate (PMMA) may leak into the posterior epidural venus plexus, provoking symptoms ranging from radicular pain to medullar compression. OBJECTIVES:To propose and test the feasibility of a procedure (cooling system) to prevent radicular irritation caused by fora...


    pub_type: 杂志文章


    authors: Kelekis AD,Martin JB,Somon T,Wetzel SG,Dietrich PY,Ruefenacht DA

    更新日期:2003-07-15 00:00:00

  • Hypoalbuminemia Increased the Length of Stay in the Treatment of Postoperative Acute Surgical Site Infection in Spinal Surgery.

    abstract:STUDY DESIGN:Multicenter retrospective study. OBJECTIVE:The aim of this study was to identify specific risk factors for increased length of stay (LOS) in the management of acute surgical site infection (SSI) following spinal surgery. SUMMARY OF BACKGROUND DATA:Postoperative SSI is a serious complication of spinal sur...


    pub_type: 杂志文章


    authors: Yamamoto Y,Shigematsu H,Iwata E,Nakajima H,Tanaka M,Okuda A,Kawasaki S,Suga Y,Masuda K,Tanaka Y

    更新日期:2020-12-01 00:00:00

  • Primary tumors of the spine.

    abstract::Eighty-two cases of primary neoplasms of the spine, diagnosed and treated at the University of Iowa, were reviewed in an attempt to identify features of diagnostic and prognostic importance, and to evaluate the effectiveness of surgical treatment with respect to survival. Thirty-one benign and 51 malignant tumors were...


    pub_type: 杂志文章


    authors: Weinstein JN,McLain RF

    更新日期:1987-11-01 00:00:00

  • MMPI disability profile: the least known, most useful screen for psychopathology in chronic occupational spinal disorders.

    abstract:STUDY DESIGN:Prospective study on predicting psychopathology in chronic occupational spinal disorders (COSDs). OBJECTIVE:To assess prevalence of specific profiles on the Minnesota Multiphasic Personality Inventory (MMPI) and their ability to predict psychopathology in a COSD cohort. SUMMARY OF BACKGROUND DATA:In the ...


    pub_type: 杂志文章


    authors: Gatchel RJ,Mayer TG,Eddington A

    更新日期:2006-12-01 00:00:00

  • Iliac Crest Bone Graft for Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Prospective Analysis of Inpatient Pain, Narcotics Consumption, and Costs.

    abstract:STUDY DESIGN:Retrospective Analysis OBJECTIVE.: The aim of this study was to determine whether an association between increased acute pain, postoperative time, and direct hospital costs exists between the use of iliac crest bone grafting (ICBG) and bone morphogenic protein (BMP)-2 following a primary, single-level mini...


    pub_type: 杂志文章


    authors: Haws BE,Khechen B,Narain AS,Hijji FY,Cardinal KL,Guntin JA,Singh K

    更新日期:2018-09-15 00:00:00

  • Trauma to anomalous cervical spine.

    abstract::A case of aplastic arch of the atlas (Keller's type) with severe injury to the cervical spine is presented. The impact of the accident was intense enough to produce bony compression of the C7 vertebra, but no injury occurred to the neural elements in the upper cervical spine. The presence of the ligamentous apparatus ...


    pub_type: 杂志文章


    authors: Weisz GM

    更新日期:1983-04-01 00:00:00

  • Does Sacral Slanting Affect Distal Adding-on in Lenke Type 1A Adolescent Idiopathic Scoliosis?

    abstract:STUDY DESIGN:A retrospective clinical study. OBJECTIVE:The purpose of this study was to identify risk factors for postoperative distal adding-on in Lenke 1A adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA:Distal adding-on is a postoperative complication associated with the Lenke type 1A curve. Although va...


    pub_type: 杂志文章


    authors: Joo YS,Hwang CJ,Cho JH,Baik JM,Cho NI,Lee DH,Lee MY,Yoon SJ,Lee CS

    更新日期:2018-09-01 00:00:00

  • Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc.

    abstract::The management of herniated lumbar intervertebral disc for patients not responding to an initial trial of conservative therapy is generally surgical. Little is known about the effect of continued conservative therapy on patients who have not improved or have deteriorated within the first 3 months. This study assessed ...


    pub_type: 杂志文章


    authors: Shvartzman L,Weingarten E,Sherry H,Levin S,Persaud A

    更新日期:1992-02-01 00:00:00

  • Do PROMIS Physical Function, Pain Interference, and Depression Correlate to the Oswestry Disability Index and Neck Disability Index in Spine Trauma Patients?

    abstract:STUDY DESIGN:Correlational study. OBJECTIVE:In spine trauma patients, we aimed to assess the correlation of patient-reported outcome measurement information system (PROMIS) physical function (PF), pain interference (PI), and Depression scores with Oswestry Disability Index (ODI) and Neck Disability Index (NDI) ODI/NDI...


    pub_type: 杂志文章


    authors: Bernstein DN,Greenstein AS,D'Amore T,Mesfin A

    更新日期:2020-06-01 00:00:00

  • Preoperative Opioid Weaning Before Major Spinal Fusion: Simulated Data, Real-World Insights.

    abstract:STUDY DESIGN:Retrospective cohort. OBJECTIVE:To identify gaps in opioid prescription immediately prior to spinal fusion and to study the effect of such simulated "opioid weaning/elimination" on risk of long-term postoperative opioid use. SUMMARY OF BACKGROUND DATA:Numerous studies have described preoperative opioid d...


    pub_type: 杂志文章


    authors: Jain N,Phillips FM,Malik AT,Khan SN

    更新日期:2021-01-15 00:00:00

  • Salvage of lumbar pseudarthrosis with customized large-diameter pedicle screws: report of two cases.

    abstract:STUDY DESIGN:A report of two cases using custom-manufactured pedicle screws for revision spinal arthrodesis for pseudarthrosis in the setting of widely dilated pedicle screw tracts. OBJECTIVE:To present surgical outcomes of a previously unreported treatment for pseudarthrosis with widely dilated pedicle screw tracts. ...


    pub_type: 杂志文章


    authors: Huang RC,Meredith DS,Kepler CK,Tropiano P

    更新日期:2011-10-15 00:00:00

  • Direct application of the TNF-alpha inhibitor, etanercept, does not affect CGRP expression and phenotypic change of DRG neurons following application of nucleus pulposus onto injured sciatic nerves in rats.

    abstract:STUDY DESIGN:Immunohistological and behavioral analysis of the effect of a tumor necrosis factor alpha (TNF-alpha) inhibitor in an injured-nerve model. OBJECTIVE:To examine the effect of direct application of a TNF-alpha inhibitor (etanercept) on injured-nerve pain caused by nucleus pulposus. SUMMARY AND BACKGROUND D...


    pub_type: 杂志文章


    authors: Norimoto M,Ohtori S,Yamashita M,Inoue G,Yamauchi K,Koshi T,Suzuki M,Orita S,Eguchi Y,Sugiura A,Ochiai N,Takaso M,Takahashi K

    更新日期:2008-10-15 00:00:00

  • Cross-cultural adaptation, reliability, and validity of the Chinese version of the STarT Back Screening Tool in patients with low back pain.

    abstract:STUDY DESIGN:Translation and psychometric testing. OBJECTIVE:The study aims to investigate the reliability and validity of the Chinese version of the STarT Back Screening Tool (STarT) in Chinese-speaking patients with low back pain (LBP) after translation and cultural adaptation. SUMMARY OF BACKGROUND DATA:To date, n...


    pub_type: 杂志文章


    authors: Luan S,Min Y,Li G,Lin C,Li X,Wu S,Ma C,Hill JC

    更新日期:2014-07-15 00:00:00

  • Patent foramen ovale and brain microembolization during scoliosis surgery in adolescents.

    abstract:STUDY DESIGN:A case series is reported. OBJECTIVE:To improve understanding of the potential mechanisms associated with cerebral microemboli during scoliosis surgery in adolescents. SUMMARY OF BACKGROUND DATA:Paradoxical cerebral fat microembolization during scoliosis surgery has been associated with right-to-left shu...


    pub_type: 杂志文章


    authors: Rodriguez RA,Sinclair B,Weatherdon D,Letts M

    更新日期:2001-08-01 00:00:00

  • Short-term Outcomes Following Cervical Laminoplasty and Decompression and Fusion With Instrumentation.

    abstract:STUDY DESIGN:Retrospective review of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database years 2010 to 2015. OBJECTIVE:Investigate which short-term outcomes differ for cervical laminoplasty and laminectomy and fusion surgeries. SUMMARY OF BACKGROUND DATA:Conflicting rep...


    pub_type: 杂志文章


    authors: Boniello A,Petrucelli P,Kerbel Y,Horn S,Bortz CA,Brown AE,Pierce KE,Alas H,Khalsa A,Passias P

    更新日期:2019-09-01 00:00:00

  • Patients with adult spinal deformity treated operatively report greater baseline pain and disability than patients treated nonoperatively; however, deformities differ between age groups.

    abstract:STUDY DESIGN:Multicenter, prospective analysis of consecutive patients with adult spinal deformity (ASD). OBJECTIVE:Identify age-related radiographical parameters associated with poor health-related quality of life (HRQOL) and treatment preferences for ASD. SUMMARY OF BACKGROUND DATA:Patients with ASD report discrepa...


    pub_type: 杂志文章


    authors: Fu KM,Bess S,Shaffrey CI,Smith JS,Lafage V,Schwab F,Burton DC,Akbarnia BA,Ames CP,Boachie-Adjei O,Deverin V,Hart RA,Hostin R,Klineberg E,Gupta M,Kebaish K,Mundis G,Mummaneni PV,International Spine Study Group.

    更新日期:2014-08-01 00:00:00

  • Clinical efficacy of spinal instrumentation in lumbar degenerative disc disease.

    abstract::In review of 871 lumbar fusion procedures performed during the last 8 years, the theoretical advantages of lumbar spinal instrumentation are not borne out in simple discogenic disease. Four groups of 30-35 patients without previous surgery who underwent fusion by different techniques were matched for age, sex, length ...


    pub_type: 杂志文章


    authors: Zucherman J,Hsu K,Picetti G 3rd,White A,Wynne G,Taylor L

    更新日期:1992-07-01 00:00:00

  • The Impact of Metastatic Spinal Tumor Location on 30-Day Perioperative Mortality and Morbidity After Surgical Decompression.

    abstract:STUDY DESIGN:A retrospective cohort study from 2011 to 2014 was performed using the American College of Surgeons National Surgical Quality Improvement Program database. OBJECTIVE:The purpose of this study was to assess the impact of tumor location in the cervical, thoracic, or lumbosacral spine on 30-day perioperative...


    pub_type: 杂志文章


    authors: Hussain AK,Vig KS,Cheung ZB,Phan K,Lima MC,Kim JS,Kaji DA,Arvind V,Cho SK

    更新日期:2018-06-01 00:00:00

  • An unusual cause of sciatica. A case report.

    abstract:STUDY DESIGN:This case report illustrates the need to be aware of extraspinal causes of sciatica. A patient with a strangulated sciatic hernia showed the clinical features of sciatic leg pain, intestinal obstruction, and a left gluteal abscess. OBJECTIVE:To highlight the need to examine the course of the sciatic nerve...


    pub_type: 杂志文章


    authors: Servant CT

    更新日期:1998-10-01 00:00:00

  • Disturbed paraspinal reflex following prolonged flexion-relaxation and recovery.

    abstract:STUDY DESIGN:Repeated measures experimental study of the effect of flexion-relaxation, recovery, and gender on paraspinal reflex dynamics. OBJECTIVE:To determine the effect of prolonged flexion-relaxation and recovery time on reflex behavior in human subjects. SUMMARY OF BACKGROUND DATA:Prolonged spinal flexion has b...


    pub_type: 杂志文章


    authors: Rogers EL,Granata KP

    更新日期:2006-04-01 00:00:00

  • New uses and refinements of the paraspinal approach to the lumbar spine.

    abstract::The paraspinal approach was described by our group in 1968. It differs from the approach described by Melvin Watkins in 1953 in that it is a longitudinal separation of the sacrospinalis group between the multifidus and longissimus, and not between the lateral border of the entire sacrospinalis group and quadratus lumb...


    pub_type: 杂志文章


    authors: Wiltse LL,Spencer CW

    更新日期:1988-06-01 00:00:00

  • Measuring physical and psychosocial function in patients with low-back pain.

    abstract::Techniques for assessing daily function in Patients with back pain are generally crude and limited in scope. We therefore examined a "health status" questionnaire, the Sickness Impact Profile (SIP) to assess its measurement characteristics in such patients. Eighty patients with mechanical low-back pain completed the S...


    pub_type: 杂志文章


    authors: Deyo RA,Diehl AK

    更新日期:1983-09-01 00:00:00

  • Back impairment and disability determination. Another attempt at objective, reliable rating.

    abstract::Present disability evaluation schedules for the low back are not scientifically based and produce very great interexaminer differences. The authors have developed a new impairment schedule based on a comprehensive review of the medical literature and the collected opinions of a large number of back specialists. Tests ...


    pub_type: 杂志文章


    authors: Clark WL,Haldeman S,Johnson P,Morris J,Schulenberger C,Trauner D,White A

    更新日期:1988-03-01 00:00:00

  • Validity and reproducibility of self-report measures of walking capacity in lumbar spinal stenosis.

    abstract:STUDY DESIGN:Measurement (validity) study. OBJECTIVE:Examine validity and reproducibility of self-report measures of walking capacity for use in patients with lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA:Treatment outcomes in patients with LSS are often determined using data from self-report questionnaire...


    pub_type: 杂志文章


    authors: Tomkins-Lane CC,Battié MC

    更新日期:2010-11-01 00:00:00

  • Congenital dumbbell neuroblastoma.

    abstract:STUDY DESIGN:New babies with neurologic deficits resulting from intraspinal extension of congenital neuroblastoma is very unusual. Two patients with congenital dumbbell neuroblastoma with paraplegia are described, and 16 other cases are reviewed. OBJECTIVE:To study the clinical features and prognosis of congenital dum...


    pub_type: 杂志文章,评审


    authors: Shimada Y,Sato K,Abe E,Suzuki T,Ishihara Y

    更新日期:1995-06-01 00:00:00

  • Morphometric evaluation of the cervico-thoracic junction. Practical considerations for posterior fixation of the spine.

    abstract:STUDY DESIGN:Linear and angular measurements were performed on 128 vertebrae (16 spines) from C5 to T5. OBJECTIVES:Vertebrae were studied to characterize vertebral shape and size changes in the cervico-thoracic region. SUMMARY OF BACKGROUND DATA:Analysis of vertebral anatomy has been extensive and well characterized....


    pub_type: 杂志文章


    authors: Stanescu S,Ebraheim NA,Yeasting R,Bailey AS,Jackson WT

    更新日期:1994-09-15 00:00:00

  • Single-level instrumented posterolateral fusion of lumbar spine with beta-tricalcium phosphate versus autograft: a prospective, randomized study with 3-year follow-up.

    abstract:STUDY DESIGN:A prospective, randomized clinical study comparing beta-tricalcium phosphate (beta-TCP) with autograft bone graft with follow-up of 3 years. OBJECTIVE:To determine the efficacy of beta-TCP as a bone graft substitute combined with local autograft obtained from decompression compared with the use of autolog...


    pub_type: 杂志文章,随机对照试验


    authors: Dai LY,Jiang LS

    更新日期:2008-05-20 00:00:00

  • Effects of subject position on measurements of flexion, extension, and lateral flexion of the spine.

    abstract::Effects of subject positions on range and repeatability of thoracic and lumbar forward flexion, extension, and lateral flexion were studied. Inclinometric methods were used, and 27 subjects were measured by two trained testers. No great differences in repeatability and range of movements were found between measurement...


    pub_type: 杂志文章


    authors: Mellin G,Kiiski R,Weckström A

    更新日期:1991-09-01 00:00:00

  • Fear of movement/(re)injury predicting chronic disabling low back pain: a prospective inception cohort study.

    abstract:STUDY DESIGN:Prospective inception cohort study. OBJECTIVE:To investigate prospectively whether pain-related fear predicts future perceived disability and participation in patients with acute low back pain (LBP). SUMMARY OF BACKGROUND DATA:There are indications that fear of movement/(re)injury, as measured by the Tam...


    pub_type: 杂志文章


    authors: Swinkels-Meewisse IE,Roelofs J,Schouten EG,Verbeek AL,Oostendorp RA,Vlaeyen JW

    更新日期:2006-03-15 00:00:00