[Detection of cyclosporin A in breast milk--is breast feeding contraindicated?].

Abstract:

:Cyclosporin A (CyA) was measured simultaneous in breast milk and maternal and fetal blood with a new monoclonal specific radioimmunoassay in a patient who was treated with Cyclosporin A during pregnancy because of kidney transplantation. CyA-levels in breast milk were 15 to 90% higher than in maternal blood. In case of breast feeding a child would take up less than 5 percent of an immunosuppressive dose. However, we would recommend ablactation because of the toxicity and the unknown side effects of CyA for the child's immunologic system.

authors

Behrens O,Kohlhaw K,Günter H,Wonigeit K,Niesert S

doi

10.1055/s-2008-1026581

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

207-9

issue

2

eissn

0016-5751

issn

1438-8804

journal_volume

49

pub_type

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