[Detection of cyclosporin A in breast milk--is breast feeding contraindicated?].


:Cyclosporin A (CyA) was measured simultaneous in breast milk and maternal and fetal blood with a new monoclonal specific radioimmunoassay in a patient who was treated with Cyclosporin A during pregnancy because of kidney transplantation. CyA-levels in breast milk were 15 to 90% higher than in maternal blood. In case of breast feeding a child would take up less than 5 percent of an immunosuppressive dose. However, we would recommend ablactation because of the toxicity and the unknown side effects of CyA for the child's immunologic system.


Behrens O,Kohlhaw K,Günter H,Wonigeit K,Niesert S




Has Abstract


1989-02-01 00:00:00












  • [Hysterosonography and its significance in the diagnosis of endometrial cancer].

    abstract::Hysterosonography is a method which enables the macroscopic spread of endometrial carcinomas in the uterus to be demonstrated. It is not a substitute for histologic findings. It only furnishes information about conditions within the organ, not beyond it. Compared to other image-producing methods used hitherto, this is...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Becker H,Hötzinger H

    更新日期:1986-10-01 00:00:00

  • [Experiences with definitive contraception--results of a follow-up study of sterilized women].

    abstract::Within the framework of a retrospective analysis, 96 patients who had undergone sterilisation at the Department of Gynaecology at the University of Cologne between 1988 and 1991, had been questioned as to whether they were content about their former decision in favour of a definitive contraception. At present, 94% of ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Neuhaus W,Marx C,Hamm W

    更新日期:1995-03-01 00:00:00

  • [Plastic surgery correction of combination craniofacial malformations. A survey for the obstetrician].

    abstract::Complex malformations of the skeleton of the cranium and face are mostly first discovered by the obstetrician. Almost all anomalies can be corrected already at infant age by means of update craniofacial surgery, provided they are diagnosed well in time and treatment is initiated directly. Surgery should be performed b...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Mühlbauer W,Heeckt P,Anderl H,Schmidt A,Höpner F,Vertesy E,Schaarschmidt B

    更新日期:1989-11-01 00:00:00

  • [Long-term studies with an anti-androgen/estrogen combination preparation of its effectiveness, liver tolerance and lipid metabolism in females].

    abstract::The usefulness of antiandrogenic therapy with cyproterone acetate for androgenisation signs and symptoms in women, when tumours are definitely not the cause, has now been confirmed world-wide in about 100,000,000 therapy cycles using the hormonal contraceptive Diane and its follow-up preparation Diane-35, which contai...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Kaiser E,Gruner S

    更新日期:1991-04-01 00:00:00

  • Cervical Cancer Screening: Defining the Need for Research.

    abstract::With the development of a National Cancer Plan published in 2012, Germany has followed the recommendations of the WHO and the EU. The first area of action listed in Germany's National Cancer Plan is improving the early detection of cancer. Both citizens and medical specialists are encouraged to take responsibility the...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Simoes E,Brucker S,Beckmann MW,Ortmann O,Albring C,Wallwiener D

    更新日期:2013-03-01 00:00:00

  • [Interstitial and intramural pregnancy--definition and sonographic references].

    abstract::Two cases of atypical implantation are presented in order to illustrate the difference between interstitial and intramural pregnancy. Ultrasonography can provide a method of early diagnosis of heterotypic sitting before the occurrence of clinical symptoms. In cases where complications already occurred, sonography can ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Krone S,Wisser J,Nerlich A,Weissenbacher ER

    更新日期:1989-02-01 00:00:00

  • [The prognostic significance of cathepsin D in primary breast cancer].

    abstract::The prognostic significance of the lysosomal protease cathepsin D in breast cancer was evaluated in a retrospective study. Cathepsin D was measured in 346 deep-frozen (-70 degrees C) cytosol specimens of primary breast carcinomas (1982-1990). Among the established prognostic factors, only axillary lymph node involveme...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Crombach G,Ingenhorst A,Göhring UJ,Scharl A,Schaeffer HJ,Stützer H,Bolte A

    更新日期:1994-10-01 00:00:00

  • The Academization of Midwifery in the Context of the Amendment of the German Midwifery Law: Current Developments and Challenges.

    abstract::Germany faces the challenge of enforcing the academization of midwifery training in the upcoming months in order to comply with Directive 2013/55/EU. This paper outlines the related developments and challenges. At the moment, midwifery training in Germany is still predominantly carried out in technical colleges. In 20...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Plappert C,Graf J,Simoes E,Schönhardt S,Abele H

    更新日期:2019-08-01 00:00:00

  • [Sickle cell disease and pregnancy].

    abstract::Three million out of 4.5 million foreigners in Germany are from countries, where sickle cell anaemia is found. Today, this disease occurs in Germany with sufficient frequency and this makes it imperative for every physician to be familiar with it. Most of the sickle cell patients today attain the reproductive age. Dur...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章,评审


    authors: Dickerhoff R

    更新日期:1990-06-01 00:00:00

  • [Doppler ultrasound diagnosis in post-term pregnancy].

    abstract::The capability of Doppler flow velocimetry to predict intrauterine growth retardation is well known. The increased morbidity and mortality rate of postterm newborns is also well known. The aim of our study was to examine if Doppler flow velocimetry is able to indicate foetal jeopardy in the postterm period. Flow veloc...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Jörn H,Funk A,Fendel H

    更新日期:1993-09-01 00:00:00

  • [Pelviscopic ovarian surgery: a new method of safe organ preserving surgery].

    abstract::For pelviscopic removal of ovarian tumours, a puncture or morcellation of the tumour used to be necessary, frequently causing the peritoneal cavity to be contaminated with contents of cysts or tumourous material. This contamination can be avoided safely by placing the intact tumour into a bag, provided that the tumour...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Volz J,Köster S,Potempa D,Volz E,Wischnik A,Melchert F

    更新日期:1993-02-01 00:00:00

  • [Retroperitoneal lipoma-aspects on differential diagnosis (author's transl)].

    abstract::A laparotomy has been performed in a 49 years old woman. Preoperatively a large ovarian cystoma has been diagnosed. Factitiously a retroperitoneal lipoma was extirpated with a weight of 12,5 kg. ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Emmrich J

    更新日期:1979-02-01 00:00:00

  • [Tuberculous mastitis--a rare differential diagnosis of non-puerperal mastitis].

    abstract::Tuberculosis in a case of non-puerperal mastitis is a rare clinical finding. A special case of a 28-year old Thai patient was diagnosed and successfully treated with an antituberculous chemotherapy. The most important diagnostic procedure was the microbiological and histological investigation to enable the diagnosis t...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Seufert R,Casper F,Herzog RE,Bauer H

    更新日期:1993-01-01 00:00:00

  • [Hereditary prolonged QT interval (Romano Ward syndrome) in obstetric management].

    abstract::In the Romano-Ward syndrome, an inherited form of abnormally prolonged QT duration is a matter for concern. The frequency-corrected QTc value in the ECG amounts to more than 0.44 s. Persons suffering from Romano-Ward syndrome are vitally endangered by attacks of arrhythmia, syncope and cardiac arrest which are trigger...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Heidegger H,von Hugo R,Plötz J

    更新日期:1993-03-01 00:00:00

  • [The significance of prenatal diagnosis of twins (author's transl)].

    abstract::By means of ultrasound and fetal electrocardiography the diagnosis of twin pregnancies can be made prenatally without any reservation; the diagnosis is even possible in the first half of pregnancy. Comparative analysis of two approximately equal collectives of in all 602 twin pregnancies--1,45% of all births in the ye...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Bolte A,Zippel HH,Berendes R,Meyer V

    更新日期:1978-04-01 00:00:00

  • [Incomplete uterine inversion in the late puerperium in placental polyp].

    abstract::The author reports on a rare case of chronic uterine inversion during the puerperium resulting in severe and dangerous haemorrhage six weeks post partum, caused by a large placental polyp. A case of this kind has so far not been described in international medical literature. ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Hübscher B

    更新日期:1986-07-01 00:00:00

  • [Intraepithelial carcinoma of the cervix uteri in young women (author's transl)].

    abstract::78 cases of cervical carcinoma in situ in women aged thirty years or less treated at the 1st Universitäts-Frauenklinik in Vienna in the period 1960-1974 are being reported. This number represents 10,7% of all 729 cases of cervical carcinoma in situ in this period. It was surprising to notice a distinct increase in the...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Kubista E,Kucera H,Krupka S

    更新日期:1977-01-01 00:00:00

  • [Cervix cytology and primary malignancies of the gastrointestinal tract].

    abstract::During the cancer check-up of a 46-year-old woman a PAP V was diagnosed in the cervical scrapings. The atypical cells of the abrasion specimens from the corpus uteri arouse strong suspicion of malignancy. Connected with the clinical data, this finding primarily indicated a metastatic involvement of the inner genitals....

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Jaluvka V,Engelhardt W

    更新日期:1987-12-01 00:00:00

  • [Intensive monitoring of the fetus sub partu--value and false interpretation].

    abstract::The past 30 years have seen dramatic advances concerning safety of the unborn child unsurpassed during 2400 years before, i.e. since the time of Hippocrates. Part of these advances is fetal monitoring during labor. It has recently been recognized that severe brain damage due to intrapartum fetal hypoxia is more rare t...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章,评审


    authors: Saling E

    更新日期:1995-11-01 00:00:00

  • C-Section Prevalence Among Obese Mothers and Neonatal Hypoglycemia: a Cohort Analysis of the Department of Gynecology and Obstetrics of the University of Lübeck.

    abstract:INTRODUCTION:Data from the World Health Organization (WHO) demonstrates an increasing prevalence of obesity in Western countries. This study investigates the influence of obesity on the mode of delivery and the occurrence of hypoglycemia in newborns. MATERIALS AND METHODS:A retrospective analysis of all deliveries at ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Neumann K,Indorf I,Härtel C,Cirkel C,Rody A,Beyer DA

    更新日期:2017-05-01 00:00:00

  • [Systemic therapy in recurrent and primary advanced cervix cancer].

    abstract::Therapeutic results in advanced cervical cancer have not been showing any progress for more than 30 years. Only by means of systemic therapy does it seem possible, that further treatment results may be obtained similar to those in squamous cell carcinoma of the head and neck. Therefore, between 1985 and 1990 we tried ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Kaufmann M,Schmid H,Junkermann H,Schönig T,von Fournier D,Bastert G

    更新日期:1991-06-01 00:00:00

  • [Comparison of the clinical value of 2 frequently used indices of fetal blood flow analysis (pulsatility index PI and resistance index RI)].

    abstract::249 blood-flow measurements were carried out with pulsed Doppler-ultrasound in the umbilical arteries and the descending aorta of 188 fetuses. The PI and the RI of the recorded flowpatterns were calculated. In a retrospective study we then calculated the validity of the prediction of a pathological fetal outcome, i.e....

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Hecher K,Ertl U,Spernol R,Haselbach H,Szalay S

    更新日期:1988-11-01 00:00:00

  • [Microinjection of spermatozoa into the oocyte. An experimental model for assisted conjugation in oligo-asthenozoospermia as a cause of sterility].

    abstract::This study investigates the possibilities to treat oligo-asthenozoospermia, a cause of sterility, by assisted conjugation. After completing acrosome reaction, normal motile spermatozoa are microinjected into mouse oocytes. After 2 hours of incubation time in medium with lactate and albumins, spermatozoa are put into d...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Mettler L,Yamada K,Kuranty A

    更新日期:1988-09-01 00:00:00

  • [Postoperative pain in patients after conventional abdominal and endoscopic surgery hysterectomy--a comparative study].

    abstract::The purpose of the present study is to determine differences in the postoperative character of pain between two study groups undergoing different techniques of hysterectomy. Therefore we examined 42 women. 21 women underwent combined laparoscopic and vaginal hysterectomy and 21 abdominal hysterectomies have been perfo...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Malik E,Scheidel P

    更新日期:1994-11-01 00:00:00

  • [Effect of pregnancy and perinatal parameters--including mode of delivery--on survival rate of "low birth weight premature infants" (less than 1,500 g)].

    abstract::A retrospective analysis of 225 very low birth weight infants (less than 1500 g) was made, to assess the influence of the mode of delivery on the survival rate. In 186 preterm deliveries which could not be prevented by therapeutic measures, we included additionally certain gestational and perinatological parameters. G...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Ruckhäberle KE,Viehweg B,Vogtmann C,Faber R,Robel R,Forberg J

    更新日期:1991-05-01 00:00:00

  • [Irradiation therapy of recurrent cervical carcinoma (author's transl)].

    abstract::A report is presented of 141 irradiated cases of recurrent cervical carcinoma, 48 (34%) of the patients have survived for more than 2 years and 21 (15%) have survived yet more than 5 years. It is noticed, that the survival-rate is neither dependent on the localisation of recurrence, nor the beginning date nor the meth...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Kucera H,Riss P,Weghaupt K

    更新日期:1980-11-01 00:00:00

  • [Sonographic diagnosis of a case of type 1 achondrogenesis in the 2d trimester].

    abstract::The authors report on a prenatal ultrasonic diagnosis of lethal osteochondrodysplasia achondrogenesis type I (Parenti-Fraccaro) in the 17th week of pregnancy. The prenatal findings were confirmed by necropsy after termination of the pregnancy. The possibility to recognize lethal skeletal disorders early in pregnancy i...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Schramm T,Nerlich A

    更新日期:1989-10-01 00:00:00

  • [The diagnostic value of lymphography in invasive carcinoma of the cervix stage 1B (author's transl)].

    abstract::In invasive carcinoma of the cervix stage 1B our investigations showed 19% lymph node metastases (n = 47) which were verified by operation and microscopic examination. In all of these patients no lympographic evidence of metastases was observed. The value of lymphography in stage 1B invasive carcinoma of the cervix is...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Zwicker H,Alder W

    更新日期:1979-04-01 00:00:00

  • [Initial experiences with a levonorgestrel-ethinyl estradiol combination for interception].

    abstract::Several authors have reported on reliable postcoital contraception, using an estrogen/gestagen combination. These studies in more than a hundred women showed, that the unprotected intercourse in less than 50% took place around ovulation. Pregnancy rates from 0.7 to 2.6% were observed. From October 1987 to July 88, 50 ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: Fitz R,Grünberger W,Vytiska-Binstorfer E

    更新日期:1989-12-01 00:00:00

  • [The risk of yeast infection, of the newborn during and after delivery (author's transl)].

    abstract::The importance of yeast infections in obstetrics was investigated in 200 pregnant women and their newborns. In the maternity patients the vagina was tested shortly before the delivery and the mouth of the neonates was tested 1 day prior to the discharge from the hospital. In 22% of the pregnant women and in 8,4% of th...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章


    authors: van Maillot K,Leipold W

    更新日期:1975-05-01 00:00:00