Abstract:
:Millions of people are blind worldwide. Sensory substitution (SS) devices (e.g., vOICe) can assist the blind by encoding a video stream into a sound pattern, recruiting visual brain areas for auditory analysis via crossmodal interactions and plasticity. SS devices often require extensive training to attain limited functionality. In contrast to conventional attention-intensive SS training that starts with visual primitives (e.g., geometrical shapes), we argue that sensory substitution can be engaged efficiently by using stimuli (such as textures) associated with intrinsic crossmodal mappings. Crossmodal mappings link images with sounds and tactile patterns. We show that intuitive SS sounds can be matched to the correct images by naive sighted participants just as well as by intensively-trained participants. This result indicates that existing crossmodal interactions and amodal sensory cortical processing may be as important in the interpretation of patterns by SS as crossmodal plasticity (e.g., the strengthening of existing connections or the formation of new ones), especially at the earlier stages of SS usage. An SS training procedure based on crossmodal mappings could both considerably improve participant performance and shorten training times, thereby enabling SS devices to significantly expand blind capabilities.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Stiles NR,Shimojo Sdoi
10.1038/srep15628subject
Has Abstractpub_date
2015-10-22 00:00:00pages
15628issn
2045-2322pii
srep15628journal_volume
5pub_type
杂志文章abstract::In this retrospective study, we investigated the impact of diabetes mellitus (DM) on patients with head and neck cancer (HNC) undergoing concurrent chemoradiotherapy (CCRT). We analyzed the demographic and clinical characteristics, treatment tolerance, and toxicities of patients with HNC undergoing primary or adjuvant...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64844-1
更新日期:2020-05-07 00:00:00
abstract::Delphinidin is a flavonoid belonging to dietary anthocyanidin family that has been reported to possess diverse anti-tumoral activities. However, the effects of delphinidin on colorectal cancer (CRC) cells and the underlying mechanisms are not fully understood. Thus, we aimed to investigate the anti-cancer activity of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55505-z
更新日期:2019-12-12 00:00:00
abstract::Raman spectroscopy is a powerful analytical method that allows deposited and/or immobilized cells to be evaluated without complex sample preparation or labeling. However, a main limitation of Raman spectroscopy in cell analysis is the extremely weak Raman intensity that results in low signal to noise ratios. Therefore...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13150
更新日期:2015-08-27 00:00:00
abstract::The selective arterial calcium injection (SACI) test is useful for patients with functional pancreatic neuroendocrine tumors (F-PNETs). This study evaluated which patients with F-PNETs would benefit from the SACI test. We retrospectively analyzed the preoperative findings of patients on computed tomography (CT), magne...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80538-0
更新日期:2021-01-08 00:00:00
abstract::The function of most long noncoding RNAs (lncRNAs) is unknown. However, recent studies reveal important roles of lncRNAs in regulating cancer-related pathways. Human antisense lncRNA-NKX2-1-AS1 partially overlaps the NKX2-1/TTF1 gene within chromosomal region 14q13.3. Amplification of this region and/or differential e...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32793-5
更新日期:2018-09-26 00:00:00
abstract::Sacha inchi (Plukenetia volubilis L.) is a shrub native to Amazon rainforests that's of commercial interest as its seeds contain 35-60% edible oil (dry weight). This oil is one of the healthiest vegetable oils due to its high polyunsaturated fatty acid content and favourable ratio of omega-6 to omega-3 fatty acids. De...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77177-w
更新日期:2020-11-24 00:00:00
abstract::CD4+Foxp3+ regulatory T cells (Tregs) are the main immune suppressors with subpopulation of inflamed-tissue related memory Tregs (mTregs) and non-related resting Treg (rTregs). Previously, Treg was proposed to be the cause of chronicity of hepatitis B virus (HBV) infection but with controversies. We then investigated ...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-017-15527-x
更新日期:2017-11-10 00:00:00
abstract::We have demonstrated a 45 μm core diameter Neodymium-doped all-solid silicate glass photonic crystal fiber laser with a single mode laser output. The structure parameters and modes information of the fiber are both demonstrated by theoretical calculations using Finite Difference Time Domain (FDTD) method and experimen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12547
更新日期:2015-07-24 00:00:00
abstract::CRISPR/Cas9-mediated genome editing is a next-generation strategy for genetic modifications. Typically, sgRNA is constitutively expressed relying on RNA polymerase III promoters. Polymerase II promoters initiate transcription in a flexible manner, but sgRNAs generated by RNA polymerase II promoter lost their nuclease ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06216-w
更新日期:2017-07-19 00:00:00
abstract::Separation of CO2 from other gasses offers environmental benefits since CO2 gas is the main contributor to global warming. Recently, graphene oxide (GO) based gas separation membranes are of interest due to their selective barrier properties. However, maintaining selectivity without sacrificing permeance is still chal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00433-z
更新日期:2017-03-28 00:00:00
abstract::Alternative tillage and rice establishment options should aim at less water and labor to produce similar or improved yields compared with traditional puddled-transplanted rice cultivation. The relative performance of these practices in terms of yield, water input, and economics varies across rice-growing regions. A gl...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-017-09742-9
更新日期:2017-08-24 00:00:00
abstract::TiNb6O17 and TiNb2O7 were synthesized using a solid-state method. The techniques were used to assess the electrochemical performance and lithium diffusion kinetics of TiNb6O17 related to the unit cell volume with TiNb2O7. The charge-discharge curves and cyclic voltammetry revealed TiNb6O17 to have a similar redox pote...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16711-9
更新日期:2017-11-30 00:00:00
abstract::Species generalization in the profound, modality-specific effects of Hedgehog pathway inhibition (HPI) in taste organ homeostasis and sensation is shown. With the HPI, cancer drug sonidegib, we demonstrate that the rat taste system, in addition to mouse, is regulated by Hedgehog signaling. After sonidegib treatment fo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34399-3
更新日期:2018-11-01 00:00:00
abstract::Plants are key determinants of soil microbial community (SMC). Legumes and grasses are distinct groups in various ecosystems; however, how they differentially shape SMC structure and functioning has yet to be explored. Here, we investigate SMC in soils grown with stylo (legume) or bahiagrass (grass). Soil metagenomic ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10613-6
更新日期:2017-08-31 00:00:00
abstract::L-selectin on T-cells is best known as an adhesion molecule that supports recruitment of blood-borne naïve and central memory cells into lymph nodes. Proteolytic shedding of the ectodomain is thought to redirect activated T-cells from lymph nodes to sites of infection. However, we have shown that activated T-cells re-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41811-z
更新日期:2019-04-02 00:00:00
abstract::Rivers are an important aquatic conduit that connects terrestrial sources of dissolved inorganic carbon (DIC) and other elements with oceanic reservoirs. The Mekong River, one of the world's largest rivers, is firstly examined to explore inter-annual fluxes of dissolved and particulate constituents during 1923-2011 an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16005
更新日期:2015-11-02 00:00:00
abstract::Microalgae and plankton can be a rich source of bioactivity. However, induction of secondary metabolite production in lab conditions can be difficult. One simple way of bypassing this issue is to collect biomass in the field and screen for bioactivity. Therefore, bulk net samples from three areas along the coast of no...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15980-8
更新日期:2017-11-20 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-54609-w
更新日期:2019-11-27 00:00:00
abstract::Three-dimensional models of kidney tissue that recapitulate human responses are needed for drug screening, disease modeling, and, ultimately, kidney organ engineering. Here, we report a bioprinting method for creating 3D human renal proximal tubules in vitro that are fully embedded within an extracellular matrix and h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34845
更新日期:2016-10-11 00:00:00
abstract::Enterovirus A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group. EV-A71 causes hand, foot and mouth disease (HFMD), with virulent variants exhibiting polio-like acute flaccid paralysis and other central nervous system manifestations. We analysed all enterovirus A71 complete genomes with collection ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41662-8
更新日期:2019-04-01 00:00:00
abstract::Coriander foliage is a distinctive spice employed on a daily basis in curry and other Indian traditional food preparations mainly for the unique flavour attributes and health benefits. Radical scavenging activity has been demonstrated previously for coriander foliage. However, specific molecules responsible were not i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-35836-z
更新日期:2018-11-27 00:00:00
abstract::The distribution of corals in Japan covers a wide range of latitudes, encompassing tropical to temperate zones. However, coral communities in temperate zones contain only a small subset of species. Among the parameters that determine the distribution of corals, temperature plays an important role. We tested the resili...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18467
更新日期:2015-12-18 00:00:00
abstract::Metamaterial full-sized absorber structures are numerically and experimentally investigated in GHz region and then examined in THz frequency. By manipulating monitoring the number and the position of the defect elements in conventional unit cells, the optimal integrative absorber structures are generated. The proposed...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27920-1
更新日期:2018-06-22 00:00:00
abstract::The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons in the lateral hypothalamus and zona incerta. MCHergic neurons project throughout the central nervous system, indicating the involvements of many physiological functions, but the role in pain has yet to be determined. In thi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19145-z
更新日期:2018-01-15 00:00:00
abstract::Liposomes or biological vesicles can be created from cholesterol, phospholipid, and water. Their stability is affected by their phospholipid composition which can influence disease treatment and drug delivery efficacy. In this study, the effect of phospholipid type on the formation and stability of liposomes using coa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58730-z
更新日期:2020-02-04 00:00:00
abstract::The objective of this study is to investigate the performance of a serpentine channel for acoustically driven selective particle filtering. The channel consists of sharp corners and straight sections, and the acoustic field is affecting the particles throughout the channel. A prototype of the separator channel is manu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43711-8
更新日期:2019-05-09 00:00:00
abstract::Rapid changes observed today in mountain glaciers need to be put into a longer-term context to understand global sea-level contributions, regional climate-glacier systems and local landscape evolution. In this study we determined volume changes for 400 mountain glaciers across the Southern Alps, New Zealand for three ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70276-8
更新日期:2020-08-07 00:00:00
abstract::MCR-1 is a phosphoethanolamine (pEtN) transferase that modifies the pEtN moiety of lipid A, conferring resistance to colistin, which is an antibiotic belonging to the class of polypeptide antibiotics known as polymyxins and is the last-line antibiotic used to treat multidrug resistant bacterial infections. Here we det...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38793
更新日期:2016-12-13 00:00:00
abstract::The association between blood urea nitrogen to creatinine ratio (UCR) and survival is uncertain in hemodialysis patients. We examined the influence of UCR on mortality and morbidity in hemodialysis patients. A total of 3,401 hemodialysis patients were prospectively followed for 4 years. The association between UCR wit...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14205-2
更新日期:2017-11-02 00:00:00
abstract::Serotonin 5-HT2C receptor is a G-protein coupled excitatory receptor that regulates several biochemical pathways and has been implicated in obesity, mental state, sleep cycles, autism, neuropsychiatric disorders and neurodegenerative diseases. The activity of 5-HT2CR is regulated via alternative splicing and A to I ed...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39940-6
更新日期:2019-03-12 00:00:00