Cytomegalovirus as an Insidious Pathogen Causing Duodenitis.

Abstract:

:A 60-year-old woman with rheumatoid arthritis treated with methotrexate for a decade complained of slight epigastric discomfort. A positive cytomegalovirus (CMV) antigenemia test indicated the probability of CMV-related gastrointestinal infection, for which esophagogastroduodenoscopy was performed. Endoscopic findings showed a non-specific duodenal mucosal lesion;however, pathological investigation revealed evidence of CMV duodenitis. There is scarce information on the clinical and pathological features of CMV-related duodenitis, likely due to its low prevalence. CMV infection in the upper gastrointestinal tract should be considered as a differential diagnosis in high-risk individuals, particularly those with symptoms relating to the digestive system. Biopsy examinations are preferable for the definitive diagnosis of CMV gastrointestinal infection, even without specific endoscopic features.

journal_name

Acta Med Okayama

journal_title

Acta medica Okayama

authors

Hagiya H,Iwamuro M,Tanaka T,Hanayama Y,Otsuka F

doi

10.18926/AMO/53679

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

319-23

issue

5

eissn

0386-300X

journal_volume

69

pub_type

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