Dynamic modeling of in vitro lipid digestion: individual fatty acid release and bioaccessibility kinetics.


:The aim of this study was to gain knowledge about the role of triacylglycerol (TAG) composition in fatty acids (FA) of o/w emulsions on both the pancreatic lipolysis kinetics and the bioaccessibility of released products (i.e. contained within the bile salt micellar phase). A mathematical model was developed and its predictions were compared to a set of experimental data obtained during an in vitro digestion of a whey protein stabilized emulsion. Modeling results show that FA residues of TAG were hydrolyzed at specific rates, inducing different bioaccessibility kinetics. The estimated lipolysis rate constants of the studied FA (C8:0, C10:0≫C18:1 n-9≫C12:0>C14:0>C16:0≈C16:1 n-7>C22:6 n-3) were in close agreement with the available literature on the substrate specificity of pancreatic lipase. Results also suggest that lipolysis products are very rapidly solubilized in the bile salt mixed micelles with no fractionation according to the FA carbon chain.


Food Chem


Food chemistry


Giang TM,Gaucel S,Brestaz P,Anton M,Meynier A,Trelea IC,Le Feunteun S




Has Abstract


2016-03-01 00:00:00












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    pub_type: 杂志文章


    authors: Anjos O,Santos AJ,Estevinho LM,Caldeira I

    更新日期:2016-08-15 00:00:00

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    journal_title:Food chemistry

    pub_type: 杂志文章


    authors: Reboredo-Rodríguez P,González-Barreiro C,Cancho-Grande B,Simal-Gándara J

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    journal_title:Food chemistry

    pub_type: 杂志文章


    authors: Pano-Farias NS,Ceballos-Magaña SG,Muñiz-Valencia R,Jurado JM,Alcázar Á,Aguayo-Villarreal IA

    更新日期:2017-12-15 00:00:00

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    journal_title:Food chemistry

    pub_type: 杂志文章


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