Pseudallescheria boydii with Aspergillus fumigatus and Aspergillus terreus in a Critically Ill Hematopoietic Stem Cell Recipient with ARDS.

Abstract:

:Pseudallescheria boydii is a fungal organism known to affect immunocompromised patients. This organism is known to cause, in severe cases, invasive infection of various organs such as the central nervous, cardiovascular, and respiratory systems. We report an unusual case of pulmonary P. boydii pneumonia in an immunocompromised critically ill patient with a co-infection of Aspergillus fumigatus and Aspergillus terreus with ARDS. This case highlights the importance of a high index of suspicion for superimposed fungal infections in patients who are critically ill and immunocompromised. Uncommon fungal pathogens should be considered in the differential diagnosis of respiratory failure, especially if diagnostic markers such as galactomannan (from BAL and serum) or 1,3-beta-D-glucan are elevated. Further diagnostic interventions are warranted when insufficient clinical improvement is observed to prevent treatment failure and adverse outcomes.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Lahmer T,Messer M,Ehmer U,Eser S,Beitz A,Fekecs L,Schmid RM,Huber W

doi

10.1007/s11046-015-9952-8

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

267-71

issue

3-4

eissn

0301-486X

issn

1573-0832

pii

10.1007/s11046-015-9952-8

journal_volume

181

pub_type

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