Abstract：
UNLABELLED:The use of cannabis as both a therapeutic agent and recreational drug is common, and its availability is increasing as a result of legalization in many countries. Among older children, the manifestations of cannabis intoxication are numerous and include both neurological and systemic manifestations that are frequently non-specific. There have been only a few reports detailing cannabis intoxication in infants and toddlers. We describe three infants who presented to the emergency department with encephalopathic signs without prominent systemic manifestations. During the initial interview of caregivers, no history of exposure to neurotoxic agents was obtained. All three patients were subsequently diagnosed with cannabis intoxication based on urine toxic screens for delta-9-tetrahydrocannabinol (THC). The infants recovered with supportive care that included fluids and monitoring. The non-specific symptomatology of cannabis intoxication in infants together with the wide differential for unexplained acute onset encephalopathy may delay diagnosis and lead to inappropriate procedures and interventions such as antimicrobial treatments and imaging studies. CONCLUSION:Healthcare personnel of emergency rooms, urgent care centers, and general clinics should be aware of the potential risk of cannabis ingestion in young infants. A thorough medical history and toxic screen are warranted in all infants with unexplained decreased sensorium.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Lavi E,Rekhtman D,Berkun Y,Wexler Idoi
10.1007/s00431-015-2639-9subject
Has Abstractpub_date
2016-03-01 00:00:00pages
417-20issue
3eissn
0340-6199issn
1432-1076pii
10.1007/s00431-015-2639-9journal_volume
175pub_type
杂志文章abstract：:Low body mass index (BMI) z score is commonly used to define undernutrition, but faltering growth allows for a complementary dynamic assessment of nutritional status. We studied the prevalence of undernutrition and faltering growth at admission in the pediatric intensive care (PICU) setting and their impacts on outcom...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00431-017-3062-1
更新日期：2018-03-01 00:00:00
abstract：:Homeopathic globules are frequently used in children as a first-line treatment. Most of these globules are coated with sugar substitutes like xylitol; these substitutes are known for their laxative effect. Our patient shows that consumption of globules coated with xylitol does not have only laxative effects. It may ca...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-010-1249-9
更新日期：2010-12-01 00:00:00
abstract：:There has been some limited progress in the understanding of the basic defect in Wilson disease and the gene concerned has been located to the chromosome region 13q14. Treatment with zinc has emerged as a definite alternative to penicillamine administration and some shortcomings and/or hazards of both forms of therapy...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF01963553
更新日期：1991-01-01 00:00:00
abstract：:The correlation between a releasable pituitary growth hormone (GH) pool and degree of growth failure was examined in 30 children with GH deficiency (group I) and 19 children with normal short stature (group II). Based on the responsiveness of GH to GH-releasing hormone (GHRH), group I, with low GH responses (below 7 n...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442468
更新日期：1988-08-01 00:00:00
abstract：:The Kabuki (Niikawa-Kuroki) syndrome was reported in 1981 by Niikawa et al. and Kuroki et al. in a total of ten unrelated Japanese children with a characteristic array of multiple congenital anomalies and mental retardation. The syndrome is characterized by a distinct face, mild to moderate mental retardation, postnat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01983409
更新日期：1994-06-01 00:00:00
abstract：:We describe a female infant with the Schinzel-Giedion syndrome. Features present in 11 patients include coarse face, midface retraction, urogenital anomalies, poor skull vault mineralisation and variable anomalies of the long bones. Outcome is poor and mental retardation is the rule among survivors. Prenatal diagnosis...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01955902
更新日期：1993-05-01 00:00:00
abstract：:Neonatal diabetes, which may be transient or permanent, is rare. Most patients are full-term but small- for-date infants. Typical symptoms of diabetes mellitus occur within the first 4 weeks of life, requiring insulin therapy and very strict blood glucose monitoring. Subsequent growth and psychomotor development are u...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF01958635
更新日期：1995-12-01 00:00:00
abstract：UNLABELLED:In acute-phase Kawasaki disease, neutrophils cause injury to the coronary arterial endothelium through the production of elastase. Previous research has demonstrated the modulation of neutrophil function and kinetics, such as development and maturation, by granulocyte colony-stimulating factor (G-CSF). To ex...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1018-5
更新日期：2002-10-01 00:00:00
abstract：UNLABELLED:Over the last few years, the importance of paediatric stroke has become more and more evident; however, there is still little known about long-term neurological and especially neuropsychological outcome of these children. By retrospective chart review, questionnaire and clinical examination with structured i...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1357-x
更新日期：2004-04-01 00:00:00
abstract：:Arterial hypertension in childhood is less frequent as compared to adulthood but is more likely to be secondary to an underlying disorder. After ruling out more obvious causes, some patients still present with strongly suspected secondary hypertension of yet unknown etiology. A number of these children have hypertensi...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-011-1440-7
更新日期：2012-10-01 00:00:00
abstract：:The Dubowitz syndrome is a rare, autosomal, recessively inherited disorder of intrauterine and postnatal growth retardation leading to microcephaly, moderate mental retardation and such characteristic facial anomalies as telecanthus, epicanthic folds, blepharophimosis, ptosis, broadening of the bridge and tip of the n...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496039
更新日期：1986-04-01 00:00:00
abstract：:Vitamin D is important for calcium homeostasis, muscle, and bone health. It has also immunomodulatory capacities in vivo and in vitro. Regulatory T cells (Treg) have been found to suppress a number of T cell-mediated immune disorders, including allergic responses and autoimmune diseases. This study aimed to investigat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1688-6
更新日期：2012-08-01 00:00:00
abstract：:Strategies for the treatment of cystathionine beta-synthase (CBS) deficiency include (1) increasing residual enzyme activity by giving pyridoxine in those patients with vitamin responsive variants, (2) reducing the load on the affected pathway with a low methionine diet and supplementing the diet with cysteine; and (3...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/pl00014308
更新日期：1998-04-01 00:00:00
abstract：:Coeliac disease and type 1 diabetes mellitus can frequently coexist, presumably due to a common genetic predisposition. The present study was designed to evaluate the frequency of coeliac disease among Hungarian diabetic children and to study the effect of gluten-free diet on glycaemic control. A total of 205 diabetic...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1103-9
更新日期：2003-01-01 00:00:00
abstract：UNLABELLED:Isolated partial 3-methylcrotonyl-CoA carboxylase (MCC) deficiency has been described to be the cause for a distinct relatively mild clinical picture in a single patient. We describe another patient with isolated partial MCC deficiency who suffered from failure to thrive, muscular hypotonia and progressive r...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050800
更新日期：1998-03-01 00:00:00
abstract：:An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02093730
更新日期：1991-04-01 00:00:00
abstract：UNLABELLED:A retrospective analysis of 218 bunk-bed accidents and a random sample survey with 991 family interviews were performed in order to establish guidelines for bunk-bed accident prevention. Falls from the top bed during sleep (35.1%) or while playing (34.4%) and falling off the ladder (23.2%) are the leading ca...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051303
更新日期：2000-06-01 00:00:00
abstract：:A 4-month-old boy was admitted for having diffuse eruption in the perianal region, legs, trunk hands, and face with failure to thrive, edema, hypoalbuminemia, and anemia. The patient was thought to have acrodermatitis enteropathica-like eruption due to malabsorption. The eruption completely resolved with enzyme supple...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-008-0825-8
更新日期：2009-01-01 00:00:00
abstract：UNLABELLED:A collaborative study, supported by the Biomed2 Programme of the European Community, was initiated to optimise the aetiological diagnosis in genetic or gonadal males with intersex disorders, a total of 67 patients with external sexual ambiguity, testicular tissue and/or a XY karyotype. In patients with gonad...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究,评审
doi：10.1007/s00431-001-0854-z
更新日期：2002-01-01 00:00:00
abstract：UNLABELLED:Sjögren syndrome (SS) is a common disorder in adults and involves both glandular and extraglandular systems. We report here four cases of childhood SS complicated by chronic thyroiditis, interstitial nephritis or sweat gland inflammation. Additionally, in one of these cases, the central nervous system was in...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02282840
更新日期：1996-10-01 00:00:00
abstract：:To clarify the relationship between hyperbilirubinaemia and abnormal results of biochemical liver function tests in infants with breast milk jaundice (BMJ), 58 breast-fed infants with indirect hyperbilirubinaemia were enrolled in this study. Sera obtained from the above infants were subjected to routine liver function...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01955928
更新日期：1991-03-01 00:00:00
abstract：:Children affected with acute myocarditis may progress rapidly into profound ventricular dysfunction and ventricular arrhythmias. The objective of this study is to assess the impact of ventricular arrhythmias on in-hospital mortality and the use of mechanical circulatory support in patients with myocarditis. Pediatric ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03687-4
更新日期：2020-11-01 00:00:00
abstract：:Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections and hospitalizations in children aged < 2 years. The aim of this retrospective, single-centre study was to examine the characteristics of patients admitted to a paediatric intensive care unit (PICU) with RSV infection followin...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-010-1376-3
更新日期：2011-07-01 00:00:00
abstract：UNLABELLED:Hypotension is a commonly diagnosed and treated complication of extremely low gestational age newborns (ELGAN), but enormous variation in diagnosis, management and clinical practice has been documented. We sought to evaluate practice regarding the management of hypotension in ELGANs and developed a web-based...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00431-013-2251-9
更新日期：2014-06-01 00:00:00
abstract：:We studied, in vitro, different commercially available components for pneumothorax drainage, i.e. drainage tubes, Heimlich flutter valve and vacuum control units. The drainage of a pneumothorax by a drainage tube was, as expected, directly dependent on Poiseuille's law and was influenced more by diameter than length. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02024337
更新日期：1989-10-01 00:00:00
abstract：UNLABELLED:In very low birth weight (VLBW) infants, colloid infusion is associated with impaired perinatal lung function and increased oxygen dependency duration. The aim of this study was to determine whether perinatal colloid infusion was associated with abnormal neurodevelopmental outcome. All perinatal fluid input ...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00431-002-0950-8
更新日期：2002-06-01 00:00:00
abstract：:Screening for coeliac disease (CD) with serum antigliadin antibodies (AGA) was performed in 1032 diabetic children and adolescents. In 8 children CD had been diagnosed before study entry. Of the remaining 1024 children, 33 had an elevated AGA titre in the first serum sample. On follow-up an elevated AGA titre was conf...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/BF00445915
更新日期：1988-11-01 00:00:00
abstract：:The clinical and biochemical response to 25-hydroxycholecalciferol (25-HCC) and vitamin D3, 150 microgram/day for 20 days has been compared in infants aged 3--18 months with nutritional rickets. The infants were allocated at random to Group I (11 infants) treated with 25HCC and Group II (9 infants) treated with vitami...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00465565
更新日期：1977-12-30 00:00:00
abstract：:To access outcome following hypoxic ischemic encephalopathy (HIE), survivors without cerebral palsy were invited for formal developmental assessment. Children aged ≥ 42 months were assessed using the NEPSY-2, Movement Assessment Battery for Children 2 (Movement ABC-2), Behavior Rating Inventory of Executive Function, ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3028-3
更新日期：2018-01-01 00:00:00
abstract：UNLABELLED:Improved surgical care during the last decades, together with advances in medical management, led to a remarkable increase in survival of patients with congenital heart disease (CHD). However, aging of the CHD population brings new challenges, and loss of follow-up of adolescents and adults with CHD is a maj...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-015-2557-x
更新日期：2015-07-01 00:00:00
