The Impact of Misuse and Diversion of Opioid Substitution Treatment Medicines: Evidence Review and Expert Consensus.

abstract：:Alcohol and illicit drug use has a significant impact on global health. Alcohol consumption is increasing worldwide, particularly in developing countries and countries in transition, leading to an increasing number of health and social problems, both acute and chronic. Illicit drug use is also increasing, particularly...

journal_title：European addiction research

authors： Monteiro MG

更新日期：2001-08-01 00:00:00

abstract：:In Spain, detoxification in general hospitals plays an important role in the medical care of patients. We aim to provide clinicians with information on the prevalence and correlates of psychiatric co-morbidity in drug abusers in detoxification. A sample of 115 substance-abuse inpatients (mean age 31.9 +/- 6.4 years) i...

journal_title：European addiction research

authors： Nocon A,Bergé D,Astals M,Martín-Santos R,Torrens M

更新日期：2007-01-01 00:00:00

abstract：:Data were collected on 1,074 opiate detoxifications conducted with lofexidine, from 40 drug dependency units in the United Kingdom. 671 patients (62.5%) attempted a detoxification in the community, with the remainder attempting an inpatient detoxification. Patients completing the detoxification started on a mean dose ...

journal_title：European addiction research

authors： Akhurst JS

更新日期：1999-03-01 00:00:00

abstract：:A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for ...

journal_title：European addiction research

authors： Soyka M,Bondy B,Benda E,Preuss U,Hegerl U,Möller H

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND/AIM:Heroin dependence is a chronic relapsing disorder characterized by the compulsion to seek and use heroin. Stress and craving are seen as key factors for heroin use. Moreover, altered hypothalamic-pituitary-adrenal (HPA) axis function has been frequently reported. However, the acute effects of diacetylmor...

journal_title：European addiction research

authors： Gerber H,Borgwardt SJ,Schmid O,Gerhard U,Joechle W,Riecher-Rössler A,Wiesbeck GA,Walter M

更新日期：2012-01-01 00:00:00

abstract：:Both heroin abuse and early life stress (ELS) affect the immune system and the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, accelerated aging due to mild inflammation has been indicated in these conditions. The present study aims to compare plasma levels of apoptosis markers, inflammatory markers, and stre...

journal_title：European addiction research

authors： Moeini M,Esmaeil N,Mokhtari HR,Eskandari N,Banafshe HR

更新日期：2020-01-01 00:00:00

abstract：:This longitudinal study of 600 families concentrates on the influence of parental anti-smoking socialization by examining both (a) the effects of eight indicators of anti-smoking socialization on adolescent smoking and (b) the influence of parental smoking on the effectiveness of their anti-smoking socialization. Robu...

journal_title：European addiction research

authors： den Exter Blokland EA,Hale WW 3rd,Meeus W,Engels RC

更新日期：2006-01-01 00:00:00

abstract：:In Europe, adolescent substance misuse increased during the 1990s. Ireland has among the highest rates of substance misuse among schoolchildren in Europe. We sought to describe the socio-demographic and drug misuse profile of children presenting to addiction treatment services in Dublin during the 1990s. Of the 9,874 ...

journal_title：European addiction research

authors： Smyth BP,O'Brien M

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Buprenorphine has already been registered in 27 European countries for maintenance therapy in opioid-dependent patients. In our office-based prescription study we applied sublingual buprenorphine, initiating the treatment at the addiction clinic with subsequent treatment at the offices of general practitio...

journal_title：European addiction research

authors： Ortner R,Jagsch R,Schindler SD,Primorac A,Fischer G,General Practitioner Addiction Team.

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...

journal_title：European addiction research

authors： Agaku IT,Filippidis FT,Vardavas CI

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. METHODS:This prospective pilot study included 332 patie...

journal_title：European addiction research

authors： Welter S,Lücke C,Lam AP,Custal C,Moeller S,Sörös P,Thiel CM,Philipsen A,Müller HHO

更新日期：2017-01-01 00:00:00

abstract：AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...

journal_title：European addiction research

authors： Dammann G,Walter M,Gremaud-Heitz D,Wolfersdorf M,Hartmann S,Wurst FM

更新日期：2012-01-01 00:00:00

abstract：:In the article the growing interest of studies on treatment systems rather than specific treatment modalities is taken as a starting point for a discussion and outlook on how the research agenda of drug treatment research will develop in the near future. The relative absence of research that provides substantial guida...

journal_title：European addiction research

authors： Bergmark A

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription...

journal_title：European addiction research

authors： Dupouy J,Maumus-Robert S,Mansiaux Y,Pariente A,Lapeyre-Mestre M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Two forms of institutionalized pressure to treatment can be distinguished in Switzerland: civil commitment and court referral. In court referral, the referred patient has the right to refuse treatment. OBJECTIVES:To compare court referrals for inpatient treatment to voluntary therapy. METHODS:Comparison of...

journal_title：European addiction research

authors： Grichting E,Uchtenhagen A,Rehm J

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:There is a high prevalence of smoking among heavy drinkers, which is often forgotten even though it has important health consequences. AIM:To evaluate the effects that providing an intensive tobacco cessation treatment simultaneously with alcohol dependence treatment versus delayed treatment (first alcoho...

journal_title：European addiction research

authors： Nieva G,Ortega LL,Mondon S,Ballbè M,Gual A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The aim of the study was to examine the practicability and implementation efficacy of an alcohol outpatient detoxification model and the concomitant 'motivational' psychotherapeutic approach. METHOD:This was an open prospective study to examine the implementation efficacy, practicability and medical safety ...

journal_title：European addiction research

authors： Soyka M,Horak M

更新日期：2004-01-01 00:00:00

abstract：:The primary source for evaluating treatment outcome in alcoholism is usually verbal self-report. Because the validity of self-report is often doubted, more objective markers for treatment outcome are needed. In this study, we compared self-report data from 238 male alcohol-dependent patients participating in a combine...

journal_title：European addiction research

authors： Mundle G,Ackermann K,Günthner A,Munkes J,Mann K

更新日期：1999-06-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...

journal_title：European addiction research

authors： Grzywacz A,Małecka I,Suchanecka A,Bieńkowski P,Samochowiec J

更新日期：2013-01-01 00:00:00

abstract：:We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...

journal_title：European addiction research

authors： Lucht M,Jahn U,Barnow S,Freyberger HJ

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METH...

journal_title：European addiction research

authors： François C,Laramée P,Rahhali N,Chalem Y,Aballéa S,Millier A,Bineau S,Toumi M,Rehm J

更新日期：2014-01-01 00:00:00

abstract：:The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other ...

journal_title：European addiction research

authors： Lieb R,Isensee B,von Sydow K,Wittchen HU

更新日期：2000-12-01 00:00:00

abstract：:Treatment of alcohol-dependent patients was primarily focused on inpatient settings in the past decades. The efficacy of these treatment programs has been evaluated in several studies and proven to be sufficient. However, with regard to the increasing costs in public healthcare systems, questions about alternative tre...

journal_title：European addiction research

authors： Bottlender M,Soyka M

更新日期：2005-01-01 00:00:00

abstract：:γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...

journal_title：European addiction research

authors： Bhattacharya IS,Watson F,Bruce M

更新日期：2011-01-01 00:00:00

abstract：:This study investigates whether antismoking peer pressure and/or nonsmoking peers are protective factors and decrease young adults' likelihood to smoke. An experiment was conducted among 59 daily-smoking young adults aged 16-24 years. The experiment consisted of four conditions. During the session, the confederate and...

journal_title：European addiction research

authors： Harakeh Z,Vollebergh WA

更新日期：2011-01-01 00:00:00

abstract：:The combination of intoxication and criminal responsibility has been a problem field for legal theory and practice for quite some time. While it has been argued in certain contexts that intoxication reduces or denies criminal responsibility, elsewhere it has been reasoned that intoxicated offenders should be held as (...

journal_title：European addiction research

authors： Fischer B,Rehm J

更新日期：1998-09-01 00:00:00

abstract：AIMS:There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness o...

journal_title：European addiction research

authors： Philips B,Wennberg P,Konradsson P,Franck J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:It has been determined that cannabis has adverse effects on brain tissue, and that increased S100 calcium binding protein B (S100B) blood levels are markers of neuronal damage. Therefore, the aim of this study was to evaluate the S100B levels in cannabis use disorder. METHOD:Thirty-two patients with cannabi...

journal_title：European addiction research

authors： Bayazit H,Cicek E,Selek S,Aksoy N,Karababa IF,Kandemir H,Basmaci Kandemir S

更新日期：2016-01-01 00:00:00

abstract：:Depression is a common co-morbid disorder in substance use disorder (SUD) patients. Hence, valid instruments are needed to screen for depression in this subpopulation. In this study, the predictive validity of the Depression, Anxiety and Stress Scale (DASS-21) for the presence of a depressive disorder was investigated...

journal_title：European addiction research

authors： Beaufort IN,De Weert-Van Oene GH,Buwalda VAJ,de Leeuw JRJ,Goudriaan AE

更新日期：2017-01-01 00:00:00

abstract：AIM:The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics was also examined. METHODS:The role of polymorphisms in the serotonin receptor 1A (5-HT1A), sero...

journal_title：European addiction research

authors： Lee YS,Choi SW,Han DH,Kim DJ,Joe KH

更新日期：2009-01-01 00:00:00