Ionic Driven Embedment of Hyaluronic Acid Coated Liposomes in Polyelectrolyte Multilayer Films for Local Therapeutic Delivery.

abstract：:Atomic hydrogen exists ubiquitously in graphene materials made by chemical methods. Yet determining the effect of hydrogen on the electrochemical performance of graphene remains a significant challenge. Here we report the experimental observations of high rate capacity in hydrogen-treated 3-dimensional (3D) graphene n...

journal_title：Scientific reports

authors： Ye J,Ong MT,Heo TW,Campbell PG,Worsley MA,Liu Y,Shin SJ,Charnvanichborikarn S,Matthews MJ,Bagge-Hansen M,Lee JR,Wood BC,Wang YM

更新日期：2015-11-05 00:00:00

abstract：:More than 20 years after the first outbreaks, the phylogenetic picture of PRRSV is still incomplete and full of gaps, especially in regards of PRRSV 1. Due to the exceptional diversity observed at the eastern borders of Europe and the low number of available sequences from Central Eastern European countries, the autho...

journal_title：Scientific reports

authors： Balka G,Podgórska K,Brar MS,Bálint Á,Cadar D,Celer V,Dénes L,Dirbakova Z,Jedryczko A,Márton L,Novosel D,Petrović T,Sirakov I,Szalay D,Toplak I,Leung FC,Stadejek T

更新日期：2018-05-17 00:00:00

abstract：:Hand preference is a conspicuous variation in human behaviour, with a worldwide proportion of around 90% of people preferring to use the right hand for many tasks, and 10% the left hand. We used the large cohort of the UK biobank (~500,000 participants) to study possible relations between early life factors and adult ...

journal_title：Scientific reports

authors： de Kovel CGF,Carrión-Castillo A,Francks C

更新日期：2019-01-24 00:00:00

abstract：:Because of its multifactorial nature, predicting the presence of cancer using a single biomarker is difficult. We aimed to establish a novel machine-learning model for predicting hepatocellular carcinoma (HCC) using real-world data obtained during clinical practice. To establish a predictive model, we developed a mach...

journal_title：Scientific reports

authors： Sato M,Morimoto K,Kajihara S,Tateishi R,Shiina S,Koike K,Yatomi Y

更新日期：2019-05-30 00:00:00

abstract：:Sepsis induced cardiac dysfunction (SIC) is a severe complication to sepsis which significantly worsens patient outcomes. It is known that bacteria have the capacity to release outer membrane vesicles (OMVs), which are nano-sized bilayered vesicles composed of lipids and proteins, that can induce a fatal inflammatory ...

journal_title：Scientific reports

authors： Svennerholm K,Park KS,Wikström J,Lässer C,Crescitelli R,Shelke GV,Jang SC,Suzuki S,Bandeira E,Olofsson CS,Lötvall J

更新日期：2017-12-12 00:00:00

abstract：:Climatic changes can induce geographic expansion and altitudinal shifts in the distribution of invasive species by offering more thermally suitable habitats. At the remote sub-Antarctic Kerguelen Islands, the predatory insect Merizodus soledadinus (Coleoptera: Carabidae), introduced in 1913, rapidly invaded coastal ha...

journal_title：Scientific reports

authors： Ouisse T,Day E,Laville L,Hendrickx F,Convey P,Renault D

更新日期：2020-01-27 00:00:00

abstract：:Development of conformal n-channel organic phototransistor (OPT) array is urgent for future applications of organic complementary circuits in portable and wearable electronics and optoelectronics. In this work, the ultrathin conformal OPT array based on air-stable n-type PTCDI-C13H27 was fabricated. The OPT array show...

journal_title：Scientific reports

authors： Liu M,Wang H,Tang Q,Zhao X,Tong Y,Liu Y

更新日期：2018-11-09 00:00:00

abstract：:Laryngeal squamous cell carcinoma is a major medical problem worldwide. Although our understanding of genetic changes and their consequences in laryngeal cancer has opened new therapeutic pathways over the years, the diagnostic as well as treatment options still need to be improved. In our previous study, we identifie...

journal_title：Scientific reports

authors： Kostrzewska-Poczekaj M,Bednarek K,Jarmuz-Szymczak M,Bodnar M,Filas V,Marszalek A,Bartochowska A,Grenman R,Kiwerska K,Szyfter K,Giefing M

更新日期：2020-01-08 00:00:00

abstract：:Seagrass meadows are threatened by coastal development and global change. In the face of these pressures, molecular techniques such as reverse transcription quantitative real-time PCR (RT-qPCR) have great potential to improve management of these ecosystems by allowing early detection of chronic stress. In RT-qPCR, the...

journal_title：Scientific reports

authors： Schliep M,Pernice M,Sinutok S,Bryant CV,York PH,Rasheed MA,Ralph PJ

更新日期：2015-11-23 00:00:00

abstract：:Survivors of childhood acute lymphoblastic leukemia (cALL) are at higher risk of developing cardiometabolic complications. We aimed at exploring the associations between biomarkers of inflammation, oxidative stress, endothelial function, endotoxemia and cardiometabolic risk factors. We conducted a cross-sectional anal...

journal_title：Scientific reports

authors： Morel S,Léveillé P,Samoilenko M,Franco A,England J,Malaquin N,Tu V,Cardin GB,Drouin S,Rodier F,Lippé S,Krajinovic M,Laverdière C,Sinnett D,Lefebvre G,Levy E,Marcil V

更新日期：2020-12-09 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic relapsing-remitting form of inflammatory bowel disease (IBD) that increases the risk of colorectal cancer, the third most common malignancy in humans. Oxidative stress is a risk factor for the development of UC. The Keap1-Nrf2-ARE pathway is one of the most important defensive mech...

journal_title：Scientific reports

authors： Lu MC,Ji JA,Jiang YL,Chen ZY,Yuan ZW,You QD,Jiang ZY

更新日期：2016-05-24 00:00:00

abstract：:A major goal of biology is to develop a quantitative ligand-binding assay that does not involve the use of radioactivity. Existing fluorescence-based assays have a serious drawback due to fluorescence quenching that accompanies the binding of fluorescently-labeled ligands to their receptors. This limitation of existin...

journal_title：Scientific reports

authors： Breen CJ,Raverdeau M,Voorheis HP

更新日期：2016-05-10 00:00:00

abstract：:Ring-opening graft polymerization (ROGP) of L-Lactide (L-LA) is a practical method of altering the physical and chemical properties of lignocellulose. Previous studies have mainly investigated cellulose and tin-based catalysts, particularly of tin(II) 2-ethylhexanoate (Sn(oct)2), at high temperatures and reported low ...

journal_title：Scientific reports

authors： Zhang X,Wang H,Liu C,Zhang A,Ren J

更新日期：2017-04-03 00:00:00

abstract：:Cell competition is a cell-cell interaction by which a cell compares its fitness to that of neighboring cells. The cell with the relatively lower fitness level is the "loser" and actively eliminated, while the cell with the relatively higher fitness level is the "winner" and survives. Recent studies have shown that ce...

journal_title：Scientific reports

authors： Chiba T,Ishihara E,Miyamura N,Narumi R,Kajita M,Fujita Y,Suzuki A,Ogawa Y,Nishina H

更新日期：2016-06-21 00:00:00

abstract：:Immunoglobulin A is the dominant antibody isotype found in mucosal secretions and enforces host-microbiota symbiosis in mice, yet selective IgA-deficiency (sIgAd) in humans is often described as asymptomatic. Here, we determined the effects of IgA deficiency on human gut microbiota composition and evaluated the possib...

journal_title：Scientific reports

authors： Catanzaro JR,Strauss JD,Bielecka A,Porto AF,Lobo FM,Urban A,Schofield WB,Palm NW

更新日期：2019-09-19 00:00:00

abstract：:Much attention has been given in the literature to the effects of astrophysical events on human and land-based life. However, little has been discussed on the resilience of life itself. Here we instead explore the statistics of events that completely sterilise an Earth-like planet with planet radii in the range 0.5-1....

journal_title：Scientific reports

authors： Sloan D,Alves Batista R,Loeb A

更新日期：2017-07-14 00:00:00

abstract：:Ghrelin is the only orexigenic peptide currently known and a potent prokinetic by promoting gastric motility but novel insights suggest that its role extends beyond satiety regulation. Whereas ghrelin was shown to provide somatic and colonic antinociception, its impact on gastric sensitivity is unknown even though sto...

journal_title：Scientific reports

authors： Meleine M,Mounien L,Atmani K,Ouelaa W,Bôle-Feysot C,Guérin C,Depoortere I,Gourcerol G

更新日期：2020-06-19 00:00:00

abstract：:Optogenetics allows precise, fast and reversible intervention in biological processes. Light-sheet microscopy allows observation of the full course of Drosophila embryonic development from egg to larva. Bringing the two approaches together allows unparalleled precision into the temporal regulation of signaling pathway...

journal_title：Scientific reports

authors： Kaur P,Saunders TE,Tolwinski NS

更新日期：2017-11-30 00:00:00

abstract：:Two polar vessels, Akademik Shokalskiy and Xuelong, were trapped by thick sea ice in the Antarctic coastal region just to the west of 144°E and between 66.5°S and 67°S in late December 2013. This event demonstrated the rapid establishment of extreme Antarctic sea ice conditions on synoptic time scales. The event was a...

journal_title：Scientific reports

authors： Wang Z,Turner J,Sun B,Li B,Liu C

更新日期：2014-06-17 00:00:00

abstract：:Chrysopidae (green lacewings) is the second largest family in Neuroptera, and it includes medium-size lacewings largely recognized by the presence of golden-colored eyes, bright green bodies and delicate wings with dense venation patterns. The subfamily Chrysopinae includes 97% of the species diversity in the family a...

journal_title：Scientific reports

authors： Jiang Y,Garzón-Orduña IJ,Winterton SL,Yang F,Liu X

更新日期：2017-08-03 00:00:00

abstract：:Transcranial focused ultrasound (US) has been demonstrated to stimulate neurons in animals and humans, but the mechanism of this effect is unknown. It has been hypothesized that US, a mechanical stimulus, may mediate cellular discharge by activating mechanosensitive ion channels embedded within cellular membranes. To ...

journal_title：Scientific reports

authors： Kubanek J,Shi J,Marsh J,Chen D,Deng C,Cui J

更新日期：2016-04-26 00:00:00

abstract：:Previous etiologic studies have indicated that both environmental and genetic factors play important roles in the occurrence and development of chronic Achilles tendinopathy (AT). A recent study documented the results of the largest genome-wide association study for chronic AT to date, indicating that MPP7, TIMP2 and ...

journal_title：Scientific reports

authors： Kang X,Tian B,Zhang L,Ge Z,Zhao Y,Zhang Y

更新日期：2019-11-26 00:00:00

abstract：:The gene PFKFB3 encodes for inducible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced intestine inflammation. However, it is unclear how nutrient overload regulates PFKFB3 expression and inflammatory responses in intestinal epithelial cells (IECs). In the present study, prim...

journal_title：Scientific reports

authors： Botchlett R,Li H,Guo X,Qi T,Zhao J,Zheng J,Woo SL,Pei Y,Liu M,Hu X,Chen G,Guo T,Yang S,Li Q,Xiao X,Huo Y,Wu C

更新日期：2016-07-08 00:00:00

abstract：:Peritoneal fibrosis (PF) is a severe complication of peritoneal dialysis, but there are few effective therapies for it. Recent studies have revealed a new biological function of trehalose as an autophagy inducer. Thus far, there are few reports regarding the therapeutic effects of trehalose on fibrotic diseases. There...

journal_title：Scientific reports

authors： Miyake T,Sakai N,Tamai A,Sato K,Kamikawa Y,Miyagawa T,Ogura H,Yamamura Y,Oshima M,Nakagawa S,Sagara A,Shinozaki Y,Toyama T,Kitajima S,Hara A,Iwata Y,Shimizu M,Furuichi K,Kaneko S,Wada T

更新日期：2020-08-31 00:00:00

abstract：:Identification of novel brominated contaminants in the environment, especially the derivatives and byproducts of brominated flame retardants (BFRs), has become a wide concern because of their adverse effects on human health. Herein, we qualitatively and quantitatively identified three byproducts of tetrabromobisphenol...

journal_title：Scientific reports

authors： Liu AF,Tian Y,Yin NY,Yu M,Qu GB,Shi JB,Du YG,Jiang GB

更新日期：2015-07-01 00:00:00

abstract：:Identifying the occurrence mechanism of drug-induced side effects (SEs) is critical for design of drug target and new drug development. The expression of genes in biological processes is regulated by transcription factors(TFs) and/or microRNAs. Most of previous studies were focused on a single level of gene or gene se...

journal_title：Scientific reports

authors： Jia X,Jin Q,Liu X,Bian X,Wang Y,Liu L,Ma H,Tan F,Gu M,Chen X

更新日期：2017-07-20 00:00:00

abstract：:Although early diagnosis and treatment reduce the risk of blindness from glaucoma, the decision on whether or not to begin treatment in patients with suspected glaucoma is often a dilemma because the majority of patients never develop definite glaucoma. A growing body of evidences suggests that posterior bowing of the...

journal_title：Scientific reports

authors： Kim JA,Kim TW,Weinreb RN,Lee EJ,Girard MJA,Mari JM

更新日期：2018-01-15 00:00:00

abstract：:Studies of morphological integration and modularity, and of anatomical complexity in human evolution typically focus on skeletal tissues. Here we provide the first network analysis of the musculoskeletal anatomy of both the fore- and hindlimbs of the two species of chimpanzee and humans. Contra long-accepted ideas, ne...

journal_title：Scientific reports

authors： Diogo R,Molnar JL,Rolian C,Esteve-Altava B

更新日期：2018-05-02 00:00:00

abstract：:Concerns related to pulmonary toxicity and non-specificity of nanoparticles have limited their clinical applications for aerosol delivery of chemotherapeutics in lung cancer. We hypothesized that pulmonary surfactant mimetic nanoparticles that offer pH responsive release specifically in tumor may be a possible solutio...

journal_title：Scientific reports

authors： Joshi N,Shirsath N,Singh A,Joshi KS,Banerjee R

更新日期：2014-11-18 00:00:00

abstract：:The large and complex genome of Pseudomonas aeruginosa, which consists of significant portions (up to 20%) of transferable genetic elements contributes to the rapid development of antibiotic resistance. The whole genome sequences of 22 strains isolated from eye and cystic fibrosis patients in Australia and India betwe...

journal_title：Scientific reports

authors： Subedi D,Vijay AK,Kohli GS,Rice SA,Willcox M

更新日期：2018-10-23 00:00:00