Abstract：
:Variation in axial formulae (i.e., number and identity of vertebrae) is an important feature in the evolution of vertebrates. Vertebrae at different axial positions exhibit a region-specific morphology. Key determinants for the establishment of particular vertebral shapes are the highly conserved Hox genes. Here, we analyzed Hox gene expression in the presacral vertebral column in the Nile crocodile in order to complement and extend a previous examination in the alligator and thus establish a Hox code for the axial skeleton of crocodilians in general. The newly determined expression of HoxA-4, C-5, B-7, and B-8 all revealed a crocodilian-specific pattern. HoxA-4 and HoxC-5 characterize cervical morphologies and the latter furthermore is associated with the position of the forelimb relative to the axial skeleton. HoxB-7 and HoxB-8 map exclusively to the dorsal vertebral region. The resulting expression patterns of these two Hox genes is the first description of their exact expression in the archosaurian embryo. Our comparative analyses of the Hox code in several amniote taxa provide new evidence that evolutionary differences in the axial skeleton correspond to changes in Hox gene expression domains. We detect two general processes: (i) expansion of a Hox gene's expression domain as well as (ii) a shift of gene expression. We infer that the ancestral archosaur Hox code may have resembled that of the crocodile. In association with the evolution of morphological traits, it may have been modified to patterns that can be observed in birds.
journal_name
Evol Devjournal_title
Evolution & developmentauthors
Böhmer C,Rauhut OW,Wörheide Gdoi
10.1111/ede.12136subject
Has Abstractpub_date
2015-09-01 00:00:00pages
258-69issue
5eissn
1520-541Xissn
1525-142Xjournal_volume
17pub_type
杂志文章abstract：:Morphological transformations can be generated by evolutionary changes in the sequence of developmental events. In this study, we examined the evolutionary dynamics of the developmental sequence on a macroevolutionary scale in teleosts. Using the information from previous reports describing the development of 31 speci...
journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12288
更新日期：2019-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章,评审
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journal_title：Evolution & development
pub_type： 杂志文章
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1046/j.1525-142x.2003.03057.x
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2011.00527.x
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2007.00181.x
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142x.1999.t01-3-.x
更新日期：1999-07-01 00:00:00
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journal_title：Evolution & development
pub_type： 历史文章,杂志文章
doi：10.1111/j.1525-142X.2011.00518.x
更新日期：2012-01-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
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更新日期：2009-07-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
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更新日期：2011-03-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2011.00513.x
更新日期：2011-11-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1046/j.1525-142x.2000.00055.x
更新日期：2000-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2008.00283.x
更新日期：2008-11-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章,评审
doi：10.1111/ede.12335
更新日期：2020-11-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12222
更新日期：2017-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12278
更新日期：2019-03-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1046/j.1525-142x.2001.01050.x
更新日期：2001-11-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2010.00405.x
更新日期：2010-03-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
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更新日期：2000-07-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2009.00319.x
更新日期：2009-03-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
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更新日期：2016-07-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12323
更新日期：2020-01-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12187
更新日期：2016-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1046/j.1525-142x.2002.01057.x
更新日期：2002-01-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2005.05020.x
更新日期：2005-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12110
更新日期：2015-01-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
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更新日期：2006-09-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2006.00108.x
更新日期：2006-07-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/ede.12287
更新日期：2019-05-01 00:00:00
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journal_title：Evolution & development
pub_type： 杂志文章
doi：10.1111/j.1525-142X.2008.00299.x
更新日期：2009-01-01 00:00:00
