Abstract:
OBJECTIVE:Extracorporeal Cardiopulmonary Resuscitation (E-CPR) is the initiation of extracorporeal life support during active chest compressions. There are no studies describing detailed neurocognitive outcomes of this population. We aim to describe the survival and neurocognitive outcomes of children who received E-CPR. METHODS:Prospective cohort study. Children who received E-CPR at the Stollery Children's Hospital between 2000 and 2010 were included. Neurocognitive follow-up, including Wechsler Preschool and Primary Scales of Intelligence, was completed at the age of 4.5 years, and at a minimum of 6 months after the E-CPR admission. RESULTS:Fifty-five patients received E-CPR between 2000 and 2010. Children with cardiac disease had a 49% survival to hospital discharge and 43% survival at age 5-years, with no survivors (n=4) in those with non-cardiac disease. Pediatric E-CPR survivors had a mean (SD) Full Scale Intelligence quotient (FSIQ) score of 76.5 (15.9); with 4 children (24%) having intellectual disability (defined as FSIQ over 2 standard deviations below the population mean; i.e., <70). Multiple Cox regression analysis found that mechanical ventilation prior to E-CPR, open chest CPR, longer duration of CPR, low pH and more red blood cells given on the first day of ECMO, and longer time for lactate to normalize on ECMO were associated with higher mortality at age 5-years. CONCLUSION:Pediatric patients with cardiac disease who required E-CPR had 43% survival at age 5 years. Of concern, the intelligence quotient in E-CPR survivors was significantly lower than the population mean, with 24% having intellectual disability.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Garcia Guerra G,Zorzela L,Robertson CM,Alton GY,Joffe AR,Moez EK,Dinu IA,Ross DB,Rebeyka IM,Lequier L,Western Canadian Complex Pediatric Therapies Follow-up Group.doi
10.1016/j.resuscitation.2015.07.034subject
Has Abstractpub_date
2015-11-01 00:00:00pages
208-13eissn
0300-9572issn
1873-1570pii
S0300-9572(15)00346-9journal_volume
96pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract:BACKGROUND:Cardiac arrest (CA) without return of spontaneous circulation can be treated with veno-arterial extracorporeal membrane oxygenation (vaECMO) implemented surgically or percutaneously. We performed a study assessing time for vaECMO percutaneous cannulation in the catheterization laboratory. METHODS:Single-cen...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.11.057
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To determine the rate of appropriate documentation of endotracheal tube (ET) position confirmation in the American Heart Association's Get With the Guidelines-Resuscitation (GWTG-R) and to determine whether outcomes of patients who experience in-hospital cardiac arrest differ in relation to documentation rat...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2012.08.329
更新日期:2013-01-01 00:00:00
abstract::Extensive research is being conducted to study the mechanism of blood flow during cardiopulmonary resuscitation (CPR). Recently, work has been published using a simple electrical model of the circulation to simulate the hemodynamics of CPR. This analog was a hard-wired circuit consisting of the heart and great vessels...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(86)90096-1
更新日期:1986-04-01 00:00:00
abstract:BACKGROUND:No previous study has investigated the safety of hand position during chest compression determined by the inter-nipple line, in which the heel of one hand is positioned on the centre of the chest between the nipples, from the standpoint of prevention of organ injury. METHODS:We measured the distance from th...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.06.030
更新日期:2009-10-01 00:00:00
abstract:AIM:Each minute is crucial in the treatment of out-of-hospital cardiac arrest (CA). Immediate chest compressions and early defibrillation are keys to good outcomes. We hypothesized that a coordinated effort of alerting trained local neighborhood volunteers (vols) simultaneously with 911 activation of professional EMS p...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.09.016
更新日期:2019-11-01 00:00:00
abstract::Consecutive admissions to two pediatric intensive care units (PICUs) in France (n = 93) and the United States (n = 248) were compared using admission demographics, and daily therapeutic and severity of illness data. Analysis of the major demographic characteristics revealed that patients in the French PICU were younge...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(89)90066-x
更新日期:1989-04-01 00:00:00
abstract:OBJECTIVE:In a previous study, ketamine suppressed Escherichia coli-induced production of the cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF). In other previous studies ketamine improved survival after E. coli inoculation. However, the relationship between cytokines and survival following ketamine tr...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2004.02.015
更新日期:2004-08-01 00:00:00
abstract::Public access defibrillation (PAD) is a promising strategy to fight sudden cardiac death. The Austrian Red Cross provided automated external defibrillators (AEDs) and basic life support (BLS) training as an "all inclusive package" combined with on site consultation and maintenance with annual retraining as a part of a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.07.026
更新日期:2006-05-01 00:00:00
abstract:AIM:The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response. The expression of urokinase plasminogen activator receptor (uPAR) is known to be induced after hypoxia and increased levels of soluble form suPAR have been measured after hypoxia and ischaemia. Our a...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.08.017
更新日期:2014-11-01 00:00:00
abstract::Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation acute myocardial infarction (STEMI). In comatose survivors of cardiac arrest, mild induced hypothermia (MIH) improves neurological recovery. In the present study, we investigated feasibility and safety of combining ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.01.016
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:the objective was to determine clinical characteristics that can quickly distinguish sudden death from massive pulmonary embolism (MPE) from other causes of sudden death. METHODS AND RESULTS:all medical examiner reports from Charlotte, NC from 1992 to 1999 (n=4926) were hand-searched for cases of sudden dea...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(00)00374-9
更新日期:2001-06-01 00:00:00
abstract:AIM OF THE STUDY:Sternal and rib fractures are frequent complications caused by chest compressions during cardiopulmonary resuscitation (CPR). This study aimed to investigate the potential association of CPR-related thoracic and abdominal injuries and compression depth measured with an accelerometer. METHODS:We analys...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.02.015
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Early defibrillation clearly improves survival from malignant arrhythmia. However, in some cases the cause of death will only be altered from arrhythmic to nonarrhythmic. We evaluated the impact of left ventricular ejection fraction (LVEF) on trend and recovery profile of beat-to-beat cardiac output (CO) and...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.06.004
更新日期:2010-09-01 00:00:00
abstract::Myocardial perfusion pressure, defined as the aortic diastolic pressure minus the right atrial diastolic pressure, correlates with coronary blood flow during cardiopulmonary resuscitation (CPR) and predicts initial resuscitation success. Whether this hemodynamic parameter can predict 24-h survival is not known. We exa...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(88)90111-6
更新日期:1988-10-01 00:00:00
abstract:INTRODUCTION:Some major trauma patients in metropolitan Perth (area 5000 km(2)) are initially transported to a secondary hospital (non-trauma centre), rather than directly to a tertiary hospital (trauma centre). They are subsequently transferred to a tertiary hospital. We compared outcomes from these different systems ...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2011.01.016
更新日期:2011-05-01 00:00:00
abstract::The purpose of this study was to compare the rewarming effectiveness of a radio frequency coil (13.56 MHz) at a specific absorption rate (SAR) of 2.5 W/kg (RF) with warm water immersion (40 degrees C) (WW) and an insulated mummy-type insulating sack (IS) under simulated field conditions. Four male subjects, ages 24-35...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章
doi:10.1016/0300-9572(94)00845-7
更新日期:1995-06-01 00:00:00
abstract:AIM:Survival after out-of-hospital cardiac arrest (OOHCA) varies between regions, but the contribution of different factors to this variability is unknown. This study examined whether survival to hospital discharge was related to receiving hospital characteristics, including bed number, capability of performing cardiac...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.12.006
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:Chest compressions are often performed at a variable rate during cardiopulmonary resuscitation (CPR). The effect of compression rate on other chest compression quality variables (compression depth, duty-cycle, leaning, performance decay over time) is unknown. This randomised controlled cross-over manikin study ...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2011.07.012
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:In cardiac arrest patients (in hospital and pre hospital) does resuscitation produce a good Quality of Life (QoL) for survivors after discharge from the hospital? METHODS:Embase, Medline, The Cochrane Database of Systematic Reviews, Academic Search Premier, the Central Database of Controlled Trials and the ...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2010.10.030
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:Recommendations for extracorporeal cardiopulmonary resuscitation (ECPR) state that appropriate patient selection is important for the sake of efficacy and cost-effectiveness of ECPR. It is not known whether first documented rhythm plays a prominent role in economic outcomes of patients with cardiac arrest wh...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.05.013
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Current cardiopulmonary resuscitation (CPR) guidelines do not define the optimal type of CPR (chest compression-only CPR [CCCPR] or conventional CPR with rescue breathing [CCRB]) to be performed by bystanders when they witness someone collapse. METHODS:Using a nationwide database of 1.17 million patients wh...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2018.02.017
更新日期:2018-05-01 00:00:00
abstract:AIM:To compare the time-dependent changes in the quality of chest compressions in 30:2 cardiopulmonary resuscitation (CPR) and hands-only cardiopulmonary resuscitation (HO-CPR) and to evaluate how individual rescuer factors affect the quality of chest compressions over time for both CPR techniques. METHODS:Total 1028 ...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2011.11.006
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine whether cardiopulmonary resuscitation (CPR) volume is associated with survival to discharge rate for out-of hospital cardiac arrest (OHCA) victims. METHODS:This study was performed in an emergency medical service (EMS) system with single-tiered basic to intermediate service leve...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2010.08.031
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:Associations between neighbourhood environments and survival outcomes after out-of-hospital cardiac arrests (OHCAs) have been proposed. The purpose of this study was to examine the association between county-level cardiopulmonary resuscitation (CPR) training rates and improvements in survival outcomes afte...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.01.012
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Public access of automated external defibrillator (AED) is an important public health strategy for improving survival of cardiac arrest. Major metropolitan cities in China are increasingly investing and implementing public access defibrillator programs, but the effectiveness of these programs remains unclear...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.05.015
更新日期:2019-07-01 00:00:00
abstract::Using the stable xenon-enhanced computed tomography (Xe-CT) method in dogs, we studied local, regional and global cerebral blood flow (LCBF, rCBF and gCBF) in two sham experiments and nine cardiac arrest experiments. Within the same experiments without arrest, gCBF and rCBF values were reproducible and stable. LCBF va...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(92)90171-8
更新日期:1992-08-01 00:00:00
abstract:AIM:Cardiopulmonary resuscitation (CPR) quality affects survival after cardiac arrest. We aimed to investigate if a smartwatch with real-time feedback can improve CPR quality by healthcare professionals. METHODS:An app providing real-time audiovisual feedback was developed for a smartwatch. Emergency Department (ED) p...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2019.04.050
更新日期:2019-07-01 00:00:00
abstract::This study compares the retention of basic life support (BLS) skills after 6 and 12 months by lay persons trained either in a conventional manner, or using a staged approach. Three classes, each of 2h, were offered to volunteers over a period of 4 months. For the conventional group, the second and third classes consis...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2003.12.014
更新日期:2004-04-01 00:00:00
abstract:AIM:To analyze the relationship between the depth of the chest compressions and the fluctuation caused in the thoracic impedance (TI) signal in out-of-hospital cardiac arrest (OHCA). The ultimate goal was to evaluate whether it is possible to identify compressions with inadequate depth using information of the TI wavef...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2013.12.035
更新日期:2014-05-01 00:00:00
abstract:AIM:To describe the relationship of gag and cough reflexes to Glasgow coma score (GCS) in Chinese adults requiring critical care. METHOD:Prospective observational study of adult patients requiring treatment in the trauma or resuscitation rooms of the Emergency Department, Prince of Wales Hospital, Hong Kong. A long co...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.07.017
更新日期:2012-01-01 00:00:00