Epigenetic regulation of DNA repair machinery in Helicobacter pylori-induced gastric carcinogenesis.

abstract：AIM:To determine if exacerbation of pre-existing chronic colitis in Winnie (Muc2 mutant) mice induces colonic dysplasia. METHODS:Winnie mice and C57BL6 as a genotype control, were administered 1% w/v dextran sulphate sodium (DSS) orally, followed by drinking water alone in week-long cycles for a total of three cycles....

journal_title：World journal of gastroenterology

authors： Randall-Demllo S,Fernando R,Brain T,Sohal SS,Cook AL,Guven N,Kunde D,Spring K,Eri R

更新日期：2016-10-07 00:00:00

abstract：AIM:To retrospectively analyze the fields of application, diagnostic yields and findings of OMOM capsule endoscopy in Chinese patients. METHODS:A database including 2400 Chinese patients who received OMOM capsule endoscopy in 27 endoscopy centers in China was retrieved from the Jianshan Science and Technology Ltd. OMO...

journal_title：World journal of gastroenterology

authors： Liao Z,Gao R,Li F,Xu C,Zhou Y,Wang JS,Li ZS

更新日期：2010-06-07 00:00:00

abstract：AIM:To determine the resistance patterns of Helicobacter pylori (H. pylori) strains isolated from patients in Beijing and monitor the change of antibiotic resistance over time. METHODS:In this prospective, serial and cross-sectional study, H. pylori cultures were successfully obtained from 371 and 950 patients (never ...

journal_title：World journal of gastroenterology

authors： Zhang YX,Zhou LY,Song ZQ,Zhang JZ,He LH,Ding Y

更新日期：2015-03-07 00:00:00

abstract：AIM:Taurine has been shown to be an effective scavenger of hypochlorous acid (HOCl). The role of HOCl is well established in tissue damage associated with inflammation and injury. In the present study, the effect of HOCl on nuclear nucleoside triphosphatase of hepatocytes and the ability of taurine to prevent this effe...

journal_title：World journal of gastroenterology

authors： Li JX,Pang YZ,Tang CS,Li ZQ

更新日期：2004-03-01 00:00:00

abstract：AIM:To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound. METHODS:TE, ultrasound, laboratory parameters and cutaneous liver signs were assessed in 291 consecutive patients with chronic liver d...

journal_title：World journal of gastroenterology

authors： Göbel T,Schadewaldt-Tümmers J,Greiner L,Poremba C,Häussinger D,Erhardt A

更新日期：2015-01-21 00:00:00

abstract：BACKGROUND:Autophagy is an evolutionarily conserved biological process in eukaryotic cells that involves lysosomal-mediated degradation and recycling of related cellular components. Recent studies have shown that autophagy plays an important role in the pathogenesis of Crohn's disease (CD). Herbal cake-partitioned moxi...

journal_title：World journal of gastroenterology

authors： Wang SY,Zhao JM,Zhou CL,Zheng HD,Huang Y,Zhao M,Zhang ZY,Wu LY,Wu HG,Liu HR

更新日期：2020-10-21 00:00:00

abstract：AIM:To evaluate safety and effect on hepatitis B virus (HBV) suppression of a long-term treatment with lamivudine (LAM) at standard (100 mg/d) or double (200 mg/d) dose in chronic hepatitis B. METHODS:This was a case study with matched controls (1:3) in patients with chronic hepatitis B with anti-HBe antibodies. RESU...

journal_title：World journal of gastroenterology

authors： Stornaiuolo G,Stanzione M,Brancaccio G,Cuomo G,Precone V,Di Biase S,Felaco FM,Piccinino F,Gaeta GB

更新日期：2007-11-14 00:00:00

abstract：AIM:To explore the role and potential mechanism of miR-30b regulation of autophagy in hepatic ischemia-reperfusion injury (IRI). METHODS:An animal model of hepatic IRI was generated in C57BL/6 mice. For in vitro studies, AML12 cells were immersed in mineral oil for 1 h and then cultured in complete Dulbecco's Modified...

journal_title：World journal of gastroenterology

authors： Li SP,He JD,Wang Z,Yu Y,Fu SY,Zhang HM,Zhang JJ,Shen ZY

更新日期：2016-05-14 00:00:00

abstract：AIM:To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS:Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 ...

journal_title：World journal of gastroenterology

authors： Abd El-Haleim EA,Bahgat AK,Saleh S

更新日期：2016-03-14 00:00:00

abstract：AIM:To evaluate the effectiveness and safety of different portal vein branch embolization agents in inducing compensatory hypertrophy of the remnant liver and to offer a theoretic basis for clinical portal vein branch embolization. METHODS:Forty-one adult dogs were included in the experiment and divided into four grou...

journal_title：World journal of gastroenterology

authors： Huang JY,Yang WZ,Li JJ,Jiang N,Zheng QB

更新日期：2006-01-21 00:00:00

abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...

journal_title：World journal of gastroenterology

authors： Lin CH,Yu JC,Chen TW,Chan DC,Chen CJ,Hsieh CB

更新日期：2005-09-14 00:00:00

abstract：:Good preparation before endoscopic procedures is essential for successful visualization. The small bowel is difficult to evaluate because of its length and complex configuration. A meta-analysis was conducted of studies comparing small bowel visualization by capsule endoscopy with and without preparation. Medical data...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2008-03-07 00:00:00

abstract：:A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasonography. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endoscopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The ...

journal_title：World journal of gastroenterology

authors： Nakajima Y,Takagi H,Sohara N,Sato K,Kakizaki S,Nomoto K,Suzuki H,Suehiro T,Shimura T,Asao T,Kuwano H,Mori M,Nishikura K

更新日期：2006-03-21 00:00:00

abstract：AIM:To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS:We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the relationship between A...

journal_title：World journal of gastroenterology

authors： Abdel-Rahman WM,Al-Khayyal NA,Nair VA,Aravind SR,Saber-Ayad M

更新日期：2017-05-21 00:00:00

abstract：AIM:To investigate protective effects and molecular mechanisms of green tea polyphenols (GTP) on non-alcoholic fatty liver disease (NAFLD) in Zucker fatty (ZF) rats. METHODS:Male ZF rats were fed a high-fat diet (HFD) for 2 wk then treated with GTP (200 mg/kg) or saline (5 mL/kg) for 8 wk, with Zucker lean rat as thei...

journal_title：World journal of gastroenterology

authors： Tan Y,Kim J,Cheng J,Ong M,Lao WG,Jin XL,Lin YG,Xiao L,Zhu XQ,Qu XQ

更新日期：2017-06-07 00:00:00

abstract：AIM:To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS:20 dogs of both sexes were used in this study. After laparotomy under anesthesia, 2 cm section of cecal end was clamped and ligated, then 1 cm cecum...

journal_title：World journal of gastroenterology

authors： Wang XC,Gui CQ,Zheng QS

更新日期：2003-03-01 00:00:00

abstract：AIM:To investigate the correlation between the serum soluble intercellular adhesion molecule-1 (sICAM-1) and the clinicopathologic features and to evaluate the possible prognostic significance of sICAM-1 concentration in colorectal cancer. METHODS:A total of 56 patients (mean age 57.3 years) having transitional cell c...

journal_title：World journal of gastroenterology

authors： Kang X,Wang F,Xie JD,Cao J,Xian PZ

更新日期：2005-07-21 00:00:00

abstract：AIM:To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis (UC), and their effect on inflammatory mediators and nuclear factor (NF)-kappaB activation in these patients. METHODS:Thirty patients with mild to moderate UC were randomly classified into two groups: sulfasalazine group, who r...

journal_title：World journal of gastroenterology

authors： Hegazy SK,El-Bedewy MM

更新日期：2010-09-07 00:00:00

abstract：:Intraductal papillary mucinous neoplasms (IPMNs) are a well-characterized group of mucin-producing cystic neoplasms of the clear malignant potential type. We report here two cases of intraductal papillary mucinous carcinoma (IPMC) with atypical manifestations. In one case, we discussed a pseudomyxoma peritonei caused ...

journal_title：World journal of gastroenterology

authors： Lee SE,Jang JY,Yang SH,Kim SW

更新日期：2007-03-14 00:00:00

abstract：:Gastrointestinal duplication is an uncommon congenital abnormality in two-thirds of cases manifesting before the age of 2 years. Ileal duplication is common while colonic duplication, either cystic or tubular, is a rather unusual clinical entity that remains asymptomatic and undiagnosed in most cases. Mostly occurring...

journal_title：World journal of gastroenterology

authors： Fotiadis C,Genetzakis M,Papandreou I,Misiakos EP,Agapitos E,Zografos GC

更新日期：2005-08-28 00:00:00

abstract：AIM:To determine the prevalence, histologic types and clinical features of primary epithelial tumours of the vermiform appendix in a predominantly black population. METHODS:All cases of primary tumours of the appendix identified by review of the histopathology records at the University of the West Indies between Janua...

journal_title：World journal of gastroenterology

authors： Graham RP,Williams NP,West KA

更新日期：2009-03-28 00:00:00

abstract：:Chronic intestinal pseudo-obstruction (CIPO) is a rare disease due to a severe gastrointestinal motility disorder which may mimic, on both clinical and radiological grounds, mechanical obstruction. We report a case of a 26-year-old woman who presented to our institution for plain abdominal radiography for referred lon...

journal_title：World journal of gastroenterology

authors： Camera L,Calabrese M,Sarnelli G,Longobardi M,Rocco A,Cuomo R,Salvatore M

更新日期：2011-06-28 00:00:00

abstract：:Hepatitis C virus (HCV) infection is estimated to affect 130-150 million people globally which corresponds to 2%-3% of the total world population. It remains the leading indication for liver transplant worldwide and has been demonstrated to negatively impact both patient and graft survival following non-hepatic organ ...

journal_title：World journal of gastroenterology

authors： Belga S,Doucette KE

更新日期：2016-01-28 00:00:00

abstract：:The liver is the commonest site of distant metastasis of colorectal cancer and nearly half of the patients with colorectal cancer ultimately develop liver involved during the course of their diseases. Surgery is the only therapy that offers the possibility of cure for patients with hepatic metastatic diseases. Five-ye...

journal_title：World journal of gastroenterology

authors： Liu LX,Zhang WH,Jiang HC

更新日期：2003-02-01 00:00:00

abstract：:Increased numbers of mucosa-associated Escherichia coli are observed in both of the major inflammatory bowel diseases, Crohn d' disease (CD) and ulcerative colitis (UC). A potential pathophysiological link between the presence of pathogenic invasive bacteria and genetic host susceptibility of patients with ileal CD is...

journal_title：World journal of gastroenterology

authors： Barnich N,Darfeuille-Michaud A

更新日期：2007-11-14 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate that both the neuronal function of the contractile system and structural apparatus of the gastrointestinal tract are affected in patients with longstanding diabetes and auto mic neuropathy. METHODS:The evoked esophageal and duodenal contractile activity to standardized bag distension was assessed us...

journal_title：World journal of gastroenterology

authors： Frokjaer JB,Andersen SD,Ejskjaer N,Funch-Jensen P,Drewes AM,Gregersen H

更新日期：2007-09-28 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：BACKGROUND:Pancreatic endocrine insufficiency after acute pancreatitis (AP) has drawn increasing attention in recent years. AIM:To assess the impact of risk factors on the development of pancreatic endocrine insufficiency after AP. METHODS:This retrospective observational long-term follow-up study was conducted in a ...

journal_title：World journal of gastroenterology

authors： Yu BJ,Li NS,He WH,He C,Wan JH,Zhu Y,Lu NH

更新日期：2020-06-21 00:00:00

abstract：AIM:To investigate the clinical efficacy and toxic effects of neoadjuvant chemotherapy using docetaxel combined with oxaliplatin and fluorouracil for treating stage III/IV gastric cancer. METHODS:A total of 53 stage III/IV gastric cancer patients were enrolled into the study and treated with neoadjuvant chemotherapy. ...

journal_title：World journal of gastroenterology

authors： Yu YJ,Sun WJ,Lu MD,Wang FH,Qi DS,Zhang Y,Li PH,Huang H,You T,Zheng ZQ

更新日期：2014-12-28 00:00:00