Abstract:
PURPOSE:To correlate the accuracy of intraoperative and surgical specimen (ex vivo) ultrasound (US) with pathological margin status at partial nephrectomy. MATERIALS AND METHODS:Patients undergoing partial nephrectomy for T1 renal tumours in the period May 2010-January 2014 at a single institution who had intraoperative specimen US were included. PN was performed by standardised technique with intraoperative tumour localisation. Following excision, surgical specimen (ex vivo) US was performed and the margin status was compared to the final histopathological analysis. The specificity of US to identify margin status was calculated as was the correlation between the ultrasonographic and final pathological margin. RESULTS:Forty-five patients were included (median age 61 years). Mean tumour size was 28.1 ± 10 mm, and 89 % were renal cell carcinomas with the remainder being oncocytomas. Forty-four cases had negative surgical margins on pathological analysis, and US had a specificity of 100 %. There was a strong correlation between the margin as measured on US and final analysis (Pearson's r = 0.86, p < 0.001). CONCLUSION:Results show that intraoperative, surgical specimen (ex vivo) US control of resection margins in patients undergoing PN is feasible and efficient. It represents a promising tool to ensure margin negativity during PN.
journal_name
Int Urol Nephroljournal_title
International urology and nephrologyauthors
Veeratterapillay R,Bromby A,Patel A,Sakthivel A,Abdelbakhy A,Gowda BD,Mutton A,Nagarajan S,Naisby GP,Bhatti Adoi
10.1007/s11255-015-1083-0subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1665-9issue
10eissn
0301-1623issn
1573-2584pii
10.1007/s11255-015-1083-0journal_volume
47pub_type
杂志文章abstract::Evidence from recent studies indicates that in patients with diabetic nephropathy combined therapy with ACE inhibitors (ACEI) and AT1-receptor antagonists (ARB) results in more complete blockade of the renin-angiotensin-aldosterone system (RAS) than monotherapy, and reduces proteinuria. Most of these trials, however, ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-008-9490-0
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:B cell-targeted immunosuppression with rituximab as primary treatment or when conventional therapy is contraindicated or unsuccessful can induce remission in idiopathic membranous nephropathy (IMN). We explored the efficacy and safety of rituximab therapy in an adult population with IMN and other primary glo...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0206-0
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Hemodialysis (HD) patients are at risk of deficiency of essential trace elements and excess of toxic trace elements. The aim of the study was to evaluate the relation between the serum levels of some trace elements and heavy metals (iron, zinc, manganese, copper, magnesium, cobalt, cadmium, and lead) and endo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-011-0055-2
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Metabolic syndrome (MetS) is increasing worldwide with the continuous increase in obesity prevalence. Chronic kidney disease (CKD) is also a major public health problem, but there is controversy over whether baseline MetS is a predictor of decreased renal function among Japanese community-dwelling middle-aged a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-019-02320-0
更新日期:2019-12-01 00:00:00
abstract::Twenty-six boys were evaluated and treated for posterior urethral valves. At the time the valves were diagnosed unilateral or bilateral vesicoureteral reflux was present in 58% of the ureters and 69% of the children, while dilatation of the upper urinary tract was present in 88% and 92%, respectively. There was a vari...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549902
更新日期:1989-01-01 00:00:00
abstract::The follow-up study has been performed in 4 male patients with nephrogenic diabetes insipidus lasting for 4 to 15 years. Hydronephrosis or hydroureter appeared to be caused by polyuria with or without urinary tract obstruction. The efficacy of drainage operation is emphasized when polyuria surpasses the transporting a...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02549772
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Bladder neck contracture (BNC) following prostatectomy has been reported in 0.5-32% of cases. While the etiology of a BNC is unclear, several factors have been associated with this complication, including blood loss, devascularization of bladder neck tissue, poor mucosal apposition and urinary extravasation....
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9239-1
更新日期:2008-01-01 00:00:00
abstract::Infertility may occur in patients with unilateral testicular torsion whose contralateral testis is intact. Depending on this observation, the physicians have begun to examine the contralateral testis. In the present prospective study we aimed to examine the histopathologic alterations occurring in the contralateral te...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550935
更新日期:1997-01-01 00:00:00
abstract::Register and Multicenter Study for Testicular Tumours Bonn was founded in September 1976. Until August 1981, from 46 institutions participating in Austria and the Federal Republic of Germany the data from a total of 1508 patients with testicular tumours have been collected and evaluated. This paper gives an overview o...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082779
更新日期:1984-01-01 00:00:00
abstract:PURPOSE:Our aim was to compare the different characteristics and outcomes of the Amplatz sheaths and single-step metallic dilators which were used for mini-PCNL procedure in a single institution. METHODS:Retrospective medical records of 236 patients who underwent mini-PCNL were reviewed and divided into Amplatz (n = 1...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-017-1516-z
更新日期:2017-04-01 00:00:00
abstract::Semen analysis and immunofluorescent antisperm antibodies were tested in 65 patients with varicocele. The mean sperm count and motility values in our study were 36.8 +/- 2.9 million per ml and 38.4 +/- 2.5 per cent, respectively. Both parameters were found not to differ significantly in three grades of varicocele. Imm...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02089408
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:The growth of solid tumors requires angiogenesis. Evidence indicates that mast cells (MCs) play an important role in tumor angiogenesis but results are not definitive. The aim of this study is to investigate the possible effects of angiogenesis and the presence of MCs on the prognosis of renal cell carcinoma ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9577-2
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Recently, there have been a few reports on the decrease in the incidence of severe Henoch-Schönlein purpura nephritis (HSPN) in Japan. To evaluate the incidence and the severity of HSPN, we examined the epidemiology and clinical manifestations of HSPN in Fukushima Prefecture over a 22-year period. METHODS:W...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-009-9701-3
更新日期:2010-12-01 00:00:00
abstract::This paper describes the case of a patient with HCV, without previous evidence of nephropathy, who following two well-tolerated cycles of treatment with interferon alone developed nephrotic syndrome after a third attempt with ribavirin associated with peginterferon alfa 2b. The patient exhibited a total remission when...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9241-7
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the clinical value of detected prostate-specific antigen (PSA) mRNA expression levels in circulating cells in patients with prostate cancer by quantitative real-time polymerase chain reaction (qRT-PCR) and to determine the effect of surgical manipulation on hematogenous dissemination. METHODS:Blo...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-008-9416-x
更新日期:2009-01-01 00:00:00
abstract::Renal oncocytoma represents a special category of renal tumours and accounts for 3-5% of renal neoplasms. Usually they are incidental findings. Most reports have demonstrated their benign nature but a few cases of high-grade oncocytomas were reported to have metastasized. In Poland, between 1971 and 1991, 7 patients (...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02768007
更新日期:1994-01-01 00:00:00
abstract::Considering the aging dialysis population of today, increasing our knowledge about the nature, diagnosis and the treatment of bone mineral density (BMD) problems in end-stage renal disease (ESRD) patients deserves more attention. Osteoporosis is basicly defined as a decrease in bone mass. Large epidemiological studies...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-006-9109-2
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Medication adherence plays an essential role in slowing the progression of chronic kidney disease (CKD). This review aims to summarise factors affecting medication adherence among these pre-dialysis CKD patients. METHODS:A systematic review of the literature was performed in Medline®, Embase®, SCOPUS® and C...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-020-02452-8
更新日期:2020-05-01 00:00:00
abstract:AIM:Skin test anergy is common in patients with uremia and during maintenance hemodialysis treatment. However, up to date only one study concerning skin test in peritoneal dialysis patients has focused on the issue. Our cross-sectional controlled study was conducted to analyze the correlation of purified protein deriva...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-020-02467-1
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Limited numbers of literatures have focused on the association between γ-glutamyltransferase (GGT) and chronic kidney disease (CKD), and their results were controversial. Therefore, in this study, we set up a large-scale cohort of Chinese population to discover and verify the association between serum GGT and C...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-016-1429-2
更新日期:2017-02-01 00:00:00
abstract::Administration of intravenous iron to supplement erythropoiesis stimulating agents (ESAs) has become a common practice in the management of anemia in patients with end-stage renal disease. Randomized clinical trials of anemia correction in this population have shown more adverse outcomes in CKD and ESRD patients assig...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-011-0028-5
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To investigate the effects of thermochemotherapy with mitomycin C (MMC) on normal rabbit bladder urothelium and to compare it with standard intravesical MMC and hyperthermia with normal saline. METHODS:Twenty-four male New Zealand rabbits, with a mean weight of 2.7 kg (in weight of 2.1–4.3 kg), were divided in...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-015-1139-1
更新日期:2016-01-01 00:00:00
abstract::Experience in the treatment of urinary bladder cancer based upon observation of 306 cases has been presented. Two hundred and thirteen patients were treated surgically by performing in 151 cases partial cystectomy and in 62 cases total cystectomy. Conservative treatment was applied in 75 patients. In the authors' opin...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082168
更新日期:1977-01-01 00:00:00
abstract::Primary CNS lymphoma (PCNSL) is a rare B cell variant non-Hodgkins lymphoma that is confined to the brain, leptomeninges, spinal cord and eyes. Its incidence is increasing, primarily due to increase in the number of organ transplantations being undertaken. The majority of the PTLD (post-transplant lymphoproliferative ...
journal_title:International urology and nephrology
pub_type: 杂志文章,评审
doi:10.1007/s11255-012-0146-8
更新日期:2013-08-01 00:00:00
abstract::In our center between 1992 and 1994 penile Mondor's disease (superficial dorsal penile vein thrombosis) was diagnosed in 5 patients aged 20-39 years. In all patients the thromboses were noted 24-48 hours after a prolonged sexual act with or without an intercourse. the main symptom was a cord-like thickening of the sup...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02550502
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:Anastomotic stricture (AS) is a well-described complication of radical retropubic prostatectomy (RRP) despite all the refinements in surgical technique. We aimed to define and discuss the role of postoperative urinary drainage on AS development. PATIENTS AND METHODS:A total of 136 patients with localized pr...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-007-9309-4
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Smooth muscle fibres are found within the superficial lamina propria of urinary bladder (Muscularis Mucosa). These muscle fibres of muscularis mucosa should be distinguished from the muscularis propria in cases with urothelial carcinoma, because the depth of infiltration affects prognosis and therapy modaliti...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/a:1024493518202
更新日期:2002-01-01 00:00:00
abstract::A study was carried out to verify the clinical usefulness of the elaborated method for the measurement of antistreptococcal antibody in revealing the streptococcal etiology of glomerulonephritis. In 158 patients with glomerulonephritis antistreptococcal antibody (ASA), circulating immune complexes (CIC) and haemolytic...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/BF02082387
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between preoperative detrusor underactivity (DU) and symptomatic bladder neck contracture (BNC) in patients undergoing radical retropubic prostatectomy (RRP), in order to identify a possible new risk factor in the etiopathogenic mechanisms of BNC after RRP. METHODS:A total of 100...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1007/s11255-013-0426-y
更新日期:2013-06-01 00:00:00
abstract::Five characteristics of neonate renal physiology, namely glomerular hypofiltration, low renal blood flow and alterations in water, sodium and potassium management, disappear during the first year of life but reoccur during senescence. However, the underlying mechanisms are different during the two periods. ...
journal_title:International urology and nephrology
pub_type: 杂志文章
doi:10.1023/b:urol.0000034681.60457.84
更新日期:2004-01-01 00:00:00