Abstract:
:The number of large neurons in the lateral vestibular nucleus of the mouse brain decreases in number after 25 months of age, from 488 at 25 months to 298 at 31 months. The number of small neurons in the nucleus remains constant up to 31 months of age. Large neurons accumulate lipofuscin from 25 months and their mean nuclear diameter increases significantly between 25 and 28 months of age. Small neurons contain very little lipofuscin even at 31 months of age and their mean nuclear diameter remains constant between 6 and 31 months. The difference in response of the two types of neurons to ageing may be due to their connections. Large neurons project to spinal motor neurons which decline in number with age and they receive projections from Purkinje cells in the anterior lobe of the cerebellum which also decline in number with age. Small neurons mainly project to the oculogyric nuclei in at least one of which (the abducens) there is no loss of neurons up to 31 months of age.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Sturrock RRsubject
Has Abstractpub_date
1989-10-01 00:00:00pages
227-32eissn
0021-8782issn
1469-7580journal_volume
166pub_type
杂志文章abstract::This paper reports on the development of a theoretical model to simulate the growth and repair of microdamage in bone. Unlike previous theories, which use simplified descriptions of damage, this approach models each individual microcrack explicitly, and also models the basic multicellular units (BMUs) that repair crac...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00194.x
更新日期:2003-08-01 00:00:00
abstract::Keratinocytes, in response to irritants, secrete pro-inflammatory mediators which recruit and activate immune and mesenchymal cells, including fibroblasts, to repair the skin. Fibroblasts respond by synthesising collagen and promoting the crosslinking extracellular matrix (ECM). We recently showed that the deletion of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12442
更新日期:2016-05-01 00:00:00
abstract::The knee joint consists of multiple interacting tissues that are prone to injury- and disease-related degeneration. Although much is known about the structure and function of the knee's constituent tissues, relatively little is known about their cellular origin and the mechanisms governing their segregation. To invest...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00966.x
更新日期:2008-11-01 00:00:00
abstract::Ultrasound of the calcaneus may be used as a cheap, ionising radiation-free and easy to use indicator of skeletal status, and hence of osteoporotic fracture risk. At present ultrasound is not widely used as it suffers from high precision errors. As ultrasound parameters are determined in part by bone mineral density (...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1998.19330449.x
更新日期:1998-10-01 00:00:00
abstract::The examination of endocranial data of archosauriforms has led to advances on the evolution of body size, nerve pathways, and sensory abilities. However, much of that research has focused on bird-line archosaurs, resulting in a skewed view of Archosauria. Phytosauria, a hypothesized sister taxon to or early-branching ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12668
更新日期:2017-11-01 00:00:00
abstract::Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::A defining feature of dentitions in modern sharks and rays is the regulated pattern order that generates multiple replacement teeth. These are arranged in labio-lingual files of replacement teeth that form in sequential time order both along the jaw and within successively initiated teeth in a deep dental lamina. Two ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12796
更新日期:2018-06-01 00:00:00
abstract::Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophage...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Motor control circuitry of the central nervous system must be flexible so that motor behaviours can be adapted to suit the varying demands of different states, developmental stages, and environments. Flexibility in motor control is largely provided by neuromodulatory systems which can adjust the output of motor circui...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12063
更新日期:2014-01-01 00:00:00
abstract::The hooked element in the pes of turtles was historically identified by most palaeontologists and embryologists as a modified fifth metatarsal, and often used as evidence to unite turtles with other reptiles with a hooked element. Some recent embryological studies, however, revealed that this element might represent a...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12103
更新日期:2013-11-01 00:00:00
abstract::This study was prompted by the prospect of transgenic pigs providing donor hearts for transplantation in human recipients. Autonomic innervation is important for the control of cardiac dynamics, especially in the conduction system. Our objective was to assess the relative distribution of autonomic nerves in the pig he...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19530341.x
更新日期:1999-10-01 00:00:00
abstract::The bioavailability of polystyrene particles (1 microns) labelled with FITC (3M Company, Düsseldorf) was tested in rats after enteral administration. Since macromolecules and particles are preferentially transported in the lymph, the number of particles was counted in the lymph of the thoracic duct over a 6 h period. ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Proximal femoral morphology and associated musculature are of special relevance to the understanding of hominoid locomotor systems. Knowledge of bone-muscle correspondence in extant hominoids forms an important comparative basis for inferring structure-function relationships in fossil hominids. However, there is still...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12270
更新日期:2015-03-01 00:00:00
abstract::This study was carried out on 208 Nigerian bony palates in dried skulls and on 30 palates obtained from Nigerian cadavers. Out of 208 dried skulls examined, there was a unilateral spine in 21.1% of cases, a bilateral spine in 36.5% and a bony canal in 5.7%. Of the dissected palates 30% revealed the presence of an osse...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::Scarring, leading to impaired function, growth and appearance, is a major problem following many forms of surgery. Fetal wounds, unlike those in the adult, are characterised by a reduced growth factor profile and the absence of scar tissue (Whitby & Ferguson, 1991 a, b). The antiparasitic drug, suramin (a heparin anal...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::Lateral nasal glands of 12-15 weeks old pups are immature. Gland acini of pups and mature dogs contain numerous electron-lucent vacuoles with basophilic, electron-dense cores. The vacuoles contain both acid and neutral glycoproteins, sialated glycoproteins being the dominant acidic moiety. Lateral and basal cytoplasmi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::The formation of a placenta is critical for successful mammalian pregnancy and requires remodelling of the uterine epithelium. In eutherian mammals, remodelling involves specific morphological changes that often correlate with the mode of embryonic attachment. Given the differences between marsupial and eutherian plac...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12610
更新日期:2017-07-01 00:00:00
abstract::The unusual occurrence of skeletal muscle in the pineal gland of the bat Rhinopoma microphyllum is described. Individual muscle fibres were centrally placed and were incompletely encapsulated by a labyrinthine network of widened spaces filled with electron-dense material. The 2.4 micron long sarcomeres consisted of we...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-02-01 00:00:00
abstract::Extended aggregates of intracellular axonemal derivatives can be seen within the apical cytoplasm of ciliated cells of apparently healthy domestic pigs. Such alterations were observed in 15 out of 20 animals. Complete (9 + 2) or incomplete (8 + 2 - 5 + 2) intracellular axonemes were found which sometimes arose from ma...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::A morphometric analysis was made of nuclei and cytoplasmic structures in electron micrographs of chondrocytes in the non-calcified layer of articular cartilage of the femoral condyles in adult mouse and dog and of the human incus. Mitochondrial volume density (% cytoplasm) was lower in dog than in mouse cells or cells...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::It is currently thought that New World monkeys, prosimians, and humans are the only primates to possess vomeronasal organs (VNOs) as adults. Recent studies of the human VNO suggest that previous investigations on Old World primates may have missed the VNO. We examined nasal septa from the chimpanzee (Pan troglodytes) ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19810077.x
更新日期:2001-01-01 00:00:00
abstract::The ACTH cells form a layer 1-8 cells thick, dorsal to the prolactin cells in the rostral pars distalis. They react only mildly with a variety of stains including PAS-lead haematoxylin. Their nuclear diameters vary seasonally in a manner that closely parallels that of the prolactin cells. The relative volumes of the A...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::A vomeronasal organ and patent nasopalatine ducts were found in adult specimens of Aotus trivirgatus, Arctocebus calabarensis, Ateles geoffroyi and Saguinus fuscicollis. The vomeronasal complex appeared to be functional except in Ateles. However, the relative size of the organ in the Platyrrhini is much reduced compar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract::Two cases with anomalous fascicles in abductor digiti minimi, noted in the course of dissecting 62 adult postmortem forearms, are described. Both fascicles arose from the flexor retinaculum and the antebrachial fascia; one was inserted into abductor digiti minimi and the other on the proximal phalanx of the 5th finger...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::A total histological grade does not necessarily distinguish between different manifestations of cartilage damage or degeneration. An accurate and reliable histological assessment method is required to separate normal and pathological tissue within a joint during treatment of degenerative joint conditions and to sub-cl...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01513.x
更新日期:2012-07-01 00:00:00
abstract::The fine structure of the intercellular junctions of the hen parathyroid gland was studied using freeze-fracture replicas and thin sections. In the conventional thin sections, desmosomes, intermediate junctions (maculae adherentes) and gap junctions were observed, and in the lanthanum-fixed sections, tight junctions (...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::In recent years, there has been increasing demand for personalized anatomy modelling for medical and industrial applications, such as ergonomics device development, clinical radiological exposure simulation, biomechanics analysis, and 3D animation character design. In this study, we constructed deformable torso phanto...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12815
更新日期:2018-07-01 00:00:00
abstract::Distinguishing arteries from veins in vivo has a great significance in clinical practices and preclinical studies. Optical imaging methods such as two-photon microscopy can provide high-resolution morphological information of tissue and are therefore extremely suitable for imaging small blood vessels. However, few opt...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13080
更新日期:2020-01-01 00:00:00
abstract::In a prospective cross-sectional ultrasound study the size of the fetal lumbar spinal canal was evaluated to determine reference values for the lumbar part of the vertebral canal. One hundred and sixty-seven pregnant women undergoing routine obstetric ultrasound were studied between 16 and 41 weeks of gestation. Exclu...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2002.00048.x
更新日期:2002-05-01 00:00:00
abstract::Internal cranial anatomy is a challenging area to study in fossilized skulls because of small sample sizes and varied post-mortem preservational alterations. This difficulty has led to the lack of correspondence between results obtained from direct osteological observation and from more indirect reconstruction methods...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2011.01427.x
更新日期:2011-12-01 00:00:00