Improvement of Physical and Wound Adhesion Properties of Silk Sericin and Polyvinyl Alcohol Dressing Using Glycerin.

Abstract:

OBJECTIVE:This study aimed to use glycerin to improve physical and wound adhesion properties of a wound dressing made of silk sericin and polyvinyl alcohol (PVA). DESIGN:Glycerin of a natural-derived plasticizer was used to modify the properties of silk sericin/PVA scaffolds. Various concentrations of glycerin were mixed with silk sericin and PVA and then fabricated into the scaffolds by a freeze-drying technique. The control study was performed to examine the properties of the silk sericin/PVA scaffolds with and without glycerin. MAIN OUTCOME MEASURES:Physical, mechanical, wound adhesion properties, the release profile of silk sericin, and in vivo safety of the silk sericin/PVA scaffolds with and without glycerin were investigated. MAIN RESULTS:The silk sericin/PVA scaffolds with glycerin exhibited more homogenous structure, less compressive modulus, higher Young modulus and elongation percentage, and a higher degree of crosslinking compared with the scaffold without glycerin. The silk sericin/PVA scaffold with 2% wt/vol glycerin showed more controlled release of silk sericin than the other scaffolds. The sustained release of silk sericin from the scaffold with glycerin would be advantageous for long-term healing of wounds. The silk sericin/PVA scaffold with 2% (wt/vol) glycerin was less adhesive to the wound compared with the scaffold without glycerin. Furthermore, the implantation of silk sericin/PVA scaffolds with 2% (wt/vol) glycerin did not cause any irritation to the tissue. CONCLUSION:The silk sericin/PVA scaffolds with glycerin were introduced as a biocompatible, more flexible, and less adhesive wound dressing than the scaffold without glycerin.

journal_name

Adv Skin Wound Care

authors

Aramwit P,Ratanavaraporn J,Siritientong T

doi

10.1097/01.ASW.0000467304.77196.b9

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

358-67

issue

8

eissn

1527-7941

issn

1538-8654

pii

00129334-201508000-00006

journal_volume

28

pub_type

杂志文章
  • Epidermal micrografts produced via an automated and minimally invasive tool form at the dermal/epidermal junction and contain proliferative cells that secrete wound healing growth factors.

    abstract:OBJECTIVE:The aim of this scientific study was to assess epidermal micrografts for formation at the dermal-epidermal (DE) junction, cellular outgrowth, and growth factor secretion. Epidermal harvesting is an autologous option that removes only the superficial epidermal layer of the skin, considerably limiting donor sit...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000470024.81711.b8

    authors: Osborne SN,Schmidt MA,Derrick K,Harper JR

    更新日期:2015-09-01 00:00:00

  • Care of the laparoscopic colectomy patient.

    abstract::Laparoscopic bowel surgery has demonstrated patient care benefits of decreased duration of hospital stay, smaller incisions, lower risk of cardiopulmonary complications, and reduced risk of small-bowel obstruction. Resection of complicated diverticular disease and inflammatory bowel disease can be technically challeng...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/00129334-200211000-00009

    authors: Senagore AJ,Erwin-Toth P

    更新日期:2002-11-01 00:00:00

  • Proxy study on minimizing risk of sacral pressure ulcers while complying with ventilator-associated pneumonia risk reduction guidelines.

    abstract::Bed positioning poses a subtle, yet important, tradeoff in the competing needs of hospitalized patients, particularly those susceptible to lower respiratory tract infections and/or pressure ulcers. Although it is widely held that a minimum 30° incline is necessary to mitigate risk of ventilator-acquired pneumonia, it ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000471877.19459.85

    authors: Crane BA,Wininger M,Kunsman M

    更新日期:2015-12-01 00:00:00

  • Cultured keratinocytes on urinary bladder matrix scaffolds increase angiogenesis and help in rapid healing of wounds.

    abstract:INTRODUCTION:Urinary Bladder Matrix (UBM) is an extracellular matrix (ECM) scaffold. It is now used in wound care management of partial and full-thickness wounds where conventional methods for wound care usually fail to give satisfactory results. OBJECTIVE:In this study, the authors are comparing the healing of full-t...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000398665.51283.44

    authors: Eweida A,Saad M,Gabr E,Marei M,Khalil MR

    更新日期:2011-06-01 00:00:00

  • The relationship between hemoglobin A(1c) values and healing time for lower extremity ulcers in individuals with diabetes.

    abstract:PROBLEM:The diabetic population is at an increased risk, up to 15% over a lifetime, to develop leg and foot ulcers due to such factors as neuropathy, ischemia, and infection. The tight control of glucose levels as possible is necessary to prevent the diabetic complications by preventing microvascular changes that predi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000358639.45784.cd

    authors: Markuson M,Hanson D,Anderson J,Langemo D,Hunter S,Thompson P,Paulson R,Rustvang D

    更新日期:2009-08-01 00:00:00

  • Bitter Melon Extract Promotes Granulation Tissue Growth and Angiogenesis in the Diabetic Wound.

    abstract:OBJECTIVE:Bitter melon is a plant fruit that has been shown to exert a hypoglycemic effect when used systemically in patients with diabetes. This study was designed to investigate the topical effect of bitter melon on diabetic wounds using the wound chamber model in rats. DESIGN:Two bilateral wound chambers were impla...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000504758.86737.76

    authors: Singh R,Garcia-Gomez I,Gudehithlu KP,Singh AK

    更新日期:2017-01-01 00:00:00

  • Gene Expression of Angiotensin-Converting Enzyme 2 Receptor in Skin and the Implications for COVID-19.

    abstract:BACKGROUND:Binding to the angiotensin-converting enzyme 2 (ACE2) receptor is a critical step for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter target cells. This enzyme is expressed in many human tissues including the lungs, but no research has demonstrated that SARS-CoV-2 can infect human skin ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000722748.73437.7d

    authors: Al-Benna S

    更新日期:2021-01-01 00:00:00

  • The Use of Allograft Skin for the Treatment of Darier Disease.

    abstract::Darier disease is an autosomal dominant skin disorder characterized by keratotic papules. After their appearance, these lesions tend to grow over time, producing large and exudative plaques that compromise the general condition of the affected patient's skin. The authors report the clinical case of a patient affected ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000694144.13825.59

    authors: D'Acunto C,Orlandi C,Purpura V,Melandri D

    更新日期:2020-10-01 00:00:00

  • Cancers mimicking fungal infections.

    abstract::Primary and metastatic malignancies may occasionally mimic or coexist with cutaneous fungal infections. The authors report 3 cases of cancers that were initially presumed to be cutaneous fungal infections. Dermatologists should maintain a low threshold for skin biopsy in patients with persistent or refractory fungal i...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000446864.26807.43

    authors: Ladizinski B,Alavi A,Jambrosic J,Mistry N,Sibbald RG

    更新日期:2014-07-01 00:00:00

  • Pressure Ulcer Prevalence by Level of Paralysis in Patients With Spinal Cord Injury in Long-term Care.

    abstract:OBJECTIVE:Scientific literature suggests pressure ulcer (PU) risk increases as immobility increases, indicating that more extensive paralysis confers a greater risk of PU. Yet the specific level of paralysis (ie, hemiplegia vs paraplegia vs quadriplegia), apart from neurodegenerative diagnoses, has never been examined ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000553109.70752.bf

    authors: Cowan LJ,Ahn H,Flores M,Yarrow J,Barks LS,Garvan C,Weaver MT,Stechmiller J

    更新日期:2019-03-01 00:00:00

  • The Ears of a Hippopotamus: Quality of Venous Leg Ulcer Care in Gauteng, South Africa.

    abstract:OBJECTIVE:To describe venous ulcer care and wound care practices in Gauteng, a province of South Africa, according to the Donabedian structure-process-outcome quality improvement model. METHODS:Forty-eight facilities were selected randomly from public and private wound care practices in Gauteng. Structured interviews ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000617848.46377.ae

    authors: Bruwer FA,Botma Y,Mulder M

    更新日期:2020-02-01 00:00:00

  • Validation of the Healthy Foot Screen: A Novel Assessment Tool for Common Clinical Abnormalities.

    abstract:GENERAL PURPOSE:The purpose of this learning activity is to provide information about the Healthy Foot Screen, a new tool for assessment of common foot abnormalities. TARGET AUDIENCE:This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000530686.16243.d5

    authors: Persaud R,Coutts PM,Brandon A,Verma L,Elliott JA,Sibbald RG

    更新日期:2018-04-01 00:00:00

  • A Quantitative Analysis of Microcirculation in Skin Defects Covered with Topical Wound Dressings or a Newly Developed Collagen Matrix.

    abstract:OBJECTIVE:Innovative skin substitutes and temporary wound dressings are frequently used in the treatment of superficial and partial-thickness wounds. The aim of this study was to compare 2 commonly used temporary skin dressings with a newly developed collagen matrix to determine changes in microcirculation as measured ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000525848.21221.b8

    authors: Held M,Medved F,Petersen W,Tolzmann DS,Rahmanian-Schwarz A,Schaller HE,Rothenberger J

    更新日期:2017-11-01 00:00:00

  • Evaluation of the incidence of pressure ulcers using hill-rom versacare surfaces.

    abstract:OBJECTIVE:This study was conducted to: (1) determine the clinical effectiveness of a low-air-loss surface, VersaCare P500, in the prevention of pressure ulcers in surgical patients; (2) determine differences in the adjusted Braden scores between those using VersaCare and VersaCare P500 mattress surfaces; and (3) explor...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000396303.13582.70

    authors: Korniewicz DM,Siegel J,Fajardo V,El-Masri M

    更新日期:2011-04-01 00:00:00

  • The effect of salivary gland extract of Lucilia sericata maggots on human dermal fibroblast proliferation within collagen/hyaluronan membrane in vitro: transmission electron microscopy study.

    abstract:BACKGROUND:Lucilia sericata maggots are applied to chronic wounds to aid healing when conventional treatments have failed. After their application into a necrotic wound, they potentially influence wound healing with a combination of specific proteinases that are involved in the remodeling of extracellular matrix. These...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000461260.03630.a0

    authors: Polakovičova S,Polák Š,Kuniaková M,Čambal M,Čaplovičová M,Kozánek M,Danišovič L,Kopáni M

    更新日期:2015-05-01 00:00:00

  • Physical assessment of the diabetic foot.

    abstract:PURPOSE:To provide physicians and nurses with an overview of diabetic foot assessment. TARGET AUDIENCE:This continuing-education activity is intended for physicians and nurses with an interest in learning about proper diabetic foot assessment. OBJECTIVES:After reading the article and taking the test, the participant ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/00129334-200303000-00007

    authors: Kravitz SR,McGuire J,Shanahan SD

    更新日期:2003-03-01 00:00:00

  • An Introduction to Skin as an Interface: Implications for Interprofessional Collaboration and Whole-Person Care.

    abstract:GENERAL PURPOSE:To increase health care professionals' awareness and perceptions of the skin as one of the largest body organs with multidimensional aspects and significant implications for interprofessional collaboration in whole-person care. TARGET AUDIENCE:This continuing education activity is intended for physicia...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000557830.01516.6b

    authors: Sherman DW,Kamel G

    更新日期:2019-06-01 00:00:00

  • Keloid Management: A Retrospective Case Review on a New Approach Using Surgical Excision, Platelet-Rich Plasma, and In-office Superficial Photon X-ray Radiation Therapy.

    abstract:OBJECTIVE:The objective of this retrospective study was to evaluate the efficacy of the authors' combination therapy protocol for keloid treatment. DESIGN:Retrospective. SETTING:Plastic surgery office-based outpatient setting in New York City. PATIENTS:Forty patients with 44 keloid scars requiring surgical excision....

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000482993.64811.74

    authors: Jones ME,Hardy C,Ridgway J

    更新日期:2016-07-01 00:00:00

  • Improvement of periulcer skin condition in venous leg ulcer patients: prospective, randomized, controlled, single-blinded clinical trial comparing a biosynthetic cellulose dressing with a foam dressing.

    abstract:OBJECTIVES:The aim of this study was to investigate the influence of a biosynthetic cellulose wound dressing (BWD) to stimulate wound healing in patients with a venous leg ulcer on periulcer skin condition when compared with standard care using a foam dressing. METHODS:Each patient with a venous ulcer received compres...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.ASW.0000431237.22658.15

    authors: Dini V,Romanelli M,Andriessen A,Barbanera S,Bertone MS,Brilli C,Abel M

    更新日期:2013-08-01 00:00:00

  • Effectiveness of Arginine Supplementation on Wound Healing in Older Adults in Acute and Chronic Settings: A Systematic Review.

    abstract:OBJECTIVE:To examine the effect of arginine supplementation on wound healing, as measured by wound size and healing rate, in older adults in acute and long-term care (LTC) settings. DATA SOURCES:PubMed, CINAHL Plus, Google Scholar, and OpenGrey databases. STUDY SELECTION:Randomized clinical trials and clinical studie...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000579700.20404.56

    authors: Schneider KL,Yahia N

    更新日期:2019-10-01 00:00:00

  • The Use of a Novel Canister-free Negative-Pressure Device in Chronic Wounds: A Retrospective Analysis.

    abstract:OBJECTIVE:Negative-pressure wound therapy (NPWT) is a mainstay in the treatment of acute and chronic wounds. Following the success of the Vacuum-Assisted Closure system (Kinetic Concepts Inc [KCI], an Acelity Company, San Antonio, Texas), many similar systems were developed with minor variations. However, these systems...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000481188.31032.52

    authors: Serena TE,Buan JS

    更新日期:2016-04-01 00:00:00

  • Development of a Nutrition Screening Tool for an Outpatient Wound Center.

    abstract:OBJECTIVE:To construct a quickly and easily administered nutrition screening tool using variables believed to be predictive of malnutrition risk in the wound patient population. DESIGN:A prospective pilot study assessed patients on a list of suspected variables, as well as the Scored Patient-Generated Subjective Globa...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000479803.09658.cb

    authors: Fulton J,Evans B,Miller S,Blasiole KN,Leone R,Beinlich N,Meehan A,Loose C

    更新日期:2016-03-01 00:00:00

  • In vitro activity of the Qoustic Wound Therapy System against planktonic and biofilm bacteria.

    abstract:OBJECTIVE:The purpose of this study was to determine whether the Qoustic Wound Therapy System (Arobella Medical, LLC, Minnetonka, Minnesota) kills planktonic bacterial cells and/or removes bacterial biofilms. DESIGN:The Qoustic Wound Therapy System was evaluated against Pseudomonas aeruginosa, Staphylococcus epidermid...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000363557.45726.41

    authors: Karau MJ,Piper KE,Steckelberg JM,Kavros SJ,Patel R

    更新日期:2010-07-01 00:00:00

  • Suspected deep tissue injury profile: a pilot study.

    abstract:PURPOSE:To enhance the learner's competence with knowledge of the results of research examining suspected deep tissue injury profiles. TARGET AUDIENCE:This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:After participating in this educational ac...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000443267.25288.87

    authors: Honaker J,Brockopp D,Moe K

    更新日期:2014-03-01 00:00:00

  • Smoking Is a Risk Factor for Wound Complications after Direct Anterior Hip Arthroplasty with Mesh Tape Closure.

    abstract:OBJECTIVE:To determine what factors increase the risk of early wound complications in patients undergoing direct anterior total hip arthroplasty whose wounds were closed with 2-octyl cyanoacrylate with mesh. METHODS:This study was a retrospective review of 75 consecutive patients who underwent direct anterior total hi...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000613544.11947.8b

    authors: Pachter CS,Garfinkel JH,Cochrane NH,Romness DW,Gladnick BP

    更新日期:2020-01-01 00:00:00

  • Reliability and predictive validity of Inlow's 60-Second Diabetic Foot Screen Tool.

    abstract:OBJECTIVE:: The purpose of this study was to assess Inlow's 60-Second Diabetic Foot Screen Tool to ascertain consistency of risk recognition for development of ulceration independent of specific assessor and practice setting. Screening tools that assist clinicians in identifying risk require validation. The objectives ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000415343.45178.91

    authors: Murphy CA,Laforet K,Da Rosa P,Tabamo F,Woodbury MG

    更新日期:2012-06-01 00:00:00

  • Outcomes in Patients Treated with a Novel, Simple Method for Hemostasis of Dermal Avulsion Injuries.

    abstract:OBJECTIVE:A recently described technique proposes a simple method to achieve permanent hemostasis of distal fingertip dermal avulsion injuries. It is simple to learn and easy to perform with readily available materials found in most emergency departments. However, long-term outcomes for patients treated with this techn...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000521049.72160.37

    authors: Dowling ST,Lin BW

    更新日期:2017-10-01 00:00:00

  • Transdermal oxygen delivery to diabetic wounds: a report of 6 cases.

    abstract:OBJECTIVE:To evaluate the use of a transdermal sustained oxygen delivery system to promote the healing of chronic lower extremity wounds in patients with diabetes. METHODS:Six patients (5 men, 1 woman; age range, 32-77 years) with diabetes and chronic lower extremity wounds unresponsive to previous multimodal therapy ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章,评审

    doi:10.1097/01.ASW.0000343722.22943.40

    authors: Hirsh F,Berlin SJ,Holtz A

    更新日期:2009-01-01 00:00:00

  • Susceptibility of Trichopyton mentagrophytes to Visible Light Wavelengths.

    abstract:OBJECTIVE:To determine whether a blue light (405 nm) could inhibit the growth of Trichopyton mentagrophytes without using a photosensitizing material as part of the treatment protocol. DESIGN:Basic physiologic randomized trial using laboratory specimens (T mentagrophytes). INTERVENTIONS/METHODS:Plated on a growth med...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000512271.19164.ef

    authors: Guffey JS,Payne W,Buchanan B,Daugherty J,Meurer L,Hensley P

    更新日期:2017-05-01 00:00:00

  • Diagnosing and treating moisture-associated skin damage.

    abstract::Certain types of moisture can cause debilitating damage to the skin. Terms such as perineal dermatitis, diaper rash, incontinence-associated dermatitis, or moisture-associated skin damage describe some of the conditions caused by moisture from wound drainage, fecal and/or urinary incontinence, and perspiration. It is ...

    journal_title:Advances in skin & wound care

    pub_type: 杂志文章

    doi:10.1097/01.ASW.0000414707.33267.92

    authors: Zulkowski K

    更新日期:2012-05-01 00:00:00