Abstract：
BACKGROUND:Many reports emphasize the role of sub-lobar resections in the treatment of small peripheral lung cancer. The aim of this study was to investigate a range of prognostic factors, including the extension of resection, which may affect the prognosis in a homogeneous group of patients. METHODS:We retrospectively reviewed the clinical records of 279 patients affected by N0 small peripheral adenocarcinoma (ADK) <3 cm that underwent surgery between 2000 and 2010. Eleven patients were excluded due to non-tumour-related death. RESULTS:There were 176 (66%) males and 92 (34%) females with a median age of 74 years (range 47-93). In the series, 229 (85%) patients received a lobar resection and only 39 (15%) a sub-lobar resection. One hundred ninety-five patients (72%) resulted stage IA while 73 (28%) stage IB. No differences in 5-year survival were observed according to: age (P=0.32), sex (P=0.42), T1a vs. T1b (P=0.31), stage IA vs. IB (P=0.51) and type of resection (P=0.29). Patients affected by ADK with a predominant lepidic growth showed a better 5-year survival (91.3% vs. 81.5%; P=0.044). The multivariate analysis confirmed the growth pattern as an independent risk factor (P=0.048). In patients with visceral pleura infiltration, the sub-lobar resection was associated with a significantly lower 5-year survival compared to lobectomy (63% vs. 90%; P=0.033). The visceral pleural infiltration was independent from ADK growth pattern, predominant lepidic vs. non-lepidic (P=0.51), but it was significantly more frequent in the ADK>2 cm (P=0.012). CONCLUSIONS:Small peripheral (<3 cm) N0 lung ADK can be easily resected by wedge or anatomical segmentectomy. The lepidic growth pattern is the main prognostic factor independently from the extension of resection however, in case of visceral pleural involvement, lobectomy reduces significantly the risk of recurrence.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Luzzi L,Marulli G,DE Palma A,Meniconi F,Ghisalberti M,Stocca F,Pagliarulo V,Loizzi M,Rea F,Gotti Gsubject
Has Abstractpub_date
2016-02-01 00:00:00pages
1-7issue
1eissn
0026-4733issn
1827-1626pii
R06Y9999N00A150031journal_volume
71pub_type
杂志文章abstract：:Sorbsan is a new dressing composed of alginate fibers extracted from seaweed. It is claimed to have important hydrophilic, haemostatic and biocompatible qualities. Sorbsan was used in the treatment of the donor site of split skin grafts in 52 patients operated in this department from 1988 to 1990. The patients of this...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-06-15 00:00:00
abstract：:Twenty autotransplantations and five allotransplantations were performed in female pigs; exocrine secretion was suppressed by injecting an acrylic glue into the ductal system; pancreatic segment was transplanted extraperitoneally in the iliac fussa. We describe an original technique most suitable to the morfologic car...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-05-31 00:00:00
abstract：:Colonsphinctorometrography (CSMG) is a new, original method for the simultaneous investigation of the motility of the descending colon, sigmoid colon, rectosigmoid junction, rectum, and internal and external anal sphincters. A 60 cm open-ended tip sound with an external diameter of 10 mm is used. Three 3 cm long stimu...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-03-15 00:00:00
abstract：:Senology is going to be an independent branch, but resistances to the acknowledgement of the senologist as a devoted professional are still under way. Nevertheless, in the last 20 years an irreversible educational training was traced out. The senologist is not only the surgeon who operates on the breast: he is also a ...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:The conservative surgery is considered currently the treatment of choice for the carcinoma of the breast in the initial stage. METHODS:From 1993 to the 2000, 46 patients (median age 52 years) affected by intraductal carcinoma of the breast, have been submitted to surgical intervention. In 10 cases (21,7%) a...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:The authors evaluate effectiveness, safety and cosmetic results obtained using the new skin closing system Medizip. METHODS:At the Thoracic Surgery Department of the National Cancer Institute (Milan) between June 1999 and March 2001, in 30 patients who underwent median sternotomy for bilateral pulmonary wed...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2003-02-01 00:00:00
abstract：:Barrett's esophagus is the most serious form of gastroesophageal reflux disease. It may develop due to uncontrolled chronic duodenogastroesophageal reflux and represents a premalignant abnormality. The question of the development of Barrett's esophagus and the progression to adenocarcinoma of the esophagus is addresse...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
abstract：:The authors report their experience on 313 liver transplantations performed in 255 patients. In 51.7% the indication to liver transplant was the cirrhosis, post alcoholic in 39.5% and post-hepatitis in 24.1%. The global mortality was 34.9% (89/255) with an actuarial survival of 53% at 74 months. We registered 10 cases...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-09-30 00:00:00
abstract：BACKGROUND:High resolution magnetic resonance cholangiopancreatography (MRCP) is a non invasive imaging modality for depicting the pancreatobiliary tree. It can demonstrate dilation, stenosis and intraductal filling defects of both the biliary and the pancreatic duct. The imaging quality of high resolution MRCP is exce...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:External hemorrhoidal thrombosis is a common disease with an acute anal pain as the major symptom. It is astonishing the lack of studies which investigates the most effective treatment and there are not guidelines. Furthermore, nobody has ever evaluated this peculiar condition in an elderly population. METH...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.18.07724-6
更新日期：2020-04-01 00:00:00
abstract：:A case of spontaneous oesophageal rupture or Boerhaave syndrome is described. The absence of the typical initial vomiting together with a clinical picture that successively indicated repeated myocardial infarction, pancreatitis and pulmonary abscess delayed diagnosis by 4 days, after which emergency thoracotomy, perfo...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Reference is made to personal experience (421 lumbar sympathectomies in 1640 vascular operations carried out over the last ten years) and the results of an enquiry addressed to more than 200 Italian surgeons are cited for the proposition that the indications for this operation are still the subject of disagreement, wh...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1981-09-30 00:00:00
abstract：:In a previous study, we have shown that caerulein relieves biliary colic pain in gallstone patients. This study was initiated to determine gallbladder and sphincter of Oddi behaviour during biliary colic and their response to caerulein. In 10 gallstone patients gallbladder volume was measured by real-time ultrasonogra...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:Anal squamous dysplasia is recognized as a spectrum of disease that ranges from low-grade intraepithelial lesions (LSIL) to high-grade squamous intraepithelial lesions (HSIL) to invasive anal squamous cell carcinoma (SCC). Recent reports have shown a significant increase in both the incidence and prevalence of both HS...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2008-10-01 00:00:00
abstract：:Pancreatoblastoma is a very rare tumor of the pancreas, affecting children in the first decade of life. Ultrasound and CT scan may be useful but pre-operative diagnosis is often quite difficult. High level of seric alpha-fetoprotein could be suggestive of pancreatoblastoma. The definitive diagnosis is however made by ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Thirty-four patients who underwent carotid-subclavian bypass (64.7%), aorto-carotid bypass (17.6%), endarterectomy of subclavian artery (5.8%) or endarterectomy of innominate artery for "subclavian" or "innominate steal" syndromes, had a follow-up studies 3-8 years since surgery. All patients demonstrated originally a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-08-15 00:00:00
abstract：:A case of intestinal occlusion is reported caused by volvulus of Meckel's diverticulum. The etiological and clinical aspects are discussed together with their implications in terms of suitable surgical therapy. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-06-30 00:00:00
abstract：:The authors report their experience concerning the outpatient echo Doppler mapping of peripheral venous circulation in the lower limbs. Out of a total of 240 patients examined, 190 showed monolateral venous insufficiency and 50 bilateral. These results were correlated to the age of the patients and showed that sapheno...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:The use of an external oblique muscle-cutaneous flap in the reconstruction of large chest wall defects after mastectomy is described. The flap is drown as a V-Y advancement-rotation flap, laterally based, on the ipsilateral abdominal wall. The flap extends from the posterior axillary line to the linea alba, vascular s...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：:A series of cases of acute pancreatitis treated between 1-XI-1972 and 1-XI-1975 is presented. A division is made between cases acute ab initio and postoperative pancreatitis, the latter further subdivided into pancreatic necroses, oedemas, and slight affections. The question of diagnosis is examined and elements indic...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1976-10-31 00:00:00
abstract：:Cholangiography carried out in laparoscopic surgery is a diagnostic exam considered by many authors to be very important for the anatomy and the research pre-existent pathologies of the biliary tree. Such are the effective advantages that many Schools suggest it be carried out any case as the risks, the costs and the ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:Surgical correction of pectus excavatum et carinatum in a series of adult patients is described. The relationship between deformity of the anterior chest wall and cardiac, respiratory and digestive disturbances is assessed. The indications for surgical management are explained. Reference is also made to the satisfacto...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1975-02-15 00:00:00
abstract：AIM:Patients undergoing excision for breast lumps prefer general anesthesia or local anesthesia plus sedation, because of the fear of pain for local anesthesia alone. The aim of this study is to show the efficacy of an eutectic mixture of local anesthetic lignocaine and prilocaine (EMLA®) in these patients. METHODS:Th...
journal_title：Minerva chirurgica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-04-01 00:00:00
abstract：:Abdomen and pelvic radiation therapy, as a complement to medical and surgery therapy in malignancies, may determine acute and chronic intestinal injuries. The acute intestinal effects of ionizing radiation are the necrosis of crypt epithelial cells and the cessation of the intestinal epithelium; late radiation injury ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：INTRODUCTION:Bronchogenic carcinomas involving the carina or the tracheo-bronchial angle represents a challenging surgical procedure because of difficult surgical techniques and complex ventilation procedures. Even though surgical outcomes for this type of procedure has improved over time, the need for surgical managem...
journal_title：Minerva chirurgica
pub_type： 杂志文章,meta分析
doi：10.23736/S0026-4733.17.07382-5
更新日期：2018-10-01 00:00:00
abstract：AIM:The aim of this article is to present a new method for treating spontaneous pneumothorax, the one window plus puncture method (1WP) in which a thin endoscope is used. METHODS:With the patient in the lateral position and under one-lung ventilation, a one-window working port was created on the ventral side. An intro...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：:In the orbital region the variety of tumors is so vast that even an expert oculoplastic surgeon may be deceived. The various tumors may be classified as benign, precancerous and malignant. Approximately 5-10% of all skin cancers occur in the eyelids. Incidence studies indicate that basal cell carcinoma is the most fre...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2013-12-01 00:00:00
abstract：:Askin's tumour is a rare malignant small cell neoplasia of the thoracic wall; it most often effects females during childhood and is characterised by limited survival. The authors report a recent case of Askin's tumour in a young adult male. The case was characterised by multiple recidivation but a long survival. The a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:The authors report the own experience about the experimental use of tissue adhesive in the colonic surgery, on 14 rabbits, with quite satisfactory result. Therefore they evince that this tissue adhesive, althought it can't replace the surgical suture, yet it can help the surgeon out of a hard colonic anastomosis. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-05-15 00:00:00
abstract：:The finding of Merkel cell carcinoma is a rare but important event owing to the highly aggressive nature of this neoplasm. The authors report three cases of Merkel cell carcinoma with different onsets which were representative of the possible range of clinical symptoms and the prognosis of this pathology. In two cases...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
