Abstract:
BACKGROUND:Epidemiological and objective studies report an association between sedentary time and lower risk of the metabolic syndrome (MetS) and its risk factors in young and middle-age adults. To date, there is a lack of objective data on the association between sedentary time and MetS among older adults. METHODS:The association between objectively measured sedentary time (accelerometry) with MetS and MetS components was examined in a large sample of older adults with mobility limitations (N=1198; mean age=78.7 ± 5.3 years) enrolled in the Lifestyle Interventions and Independence for Elders (LIFE) study. Participants were divided into tertiles according to percentage of daily sedentary time, and the relation between sedentary time with MetS and MetS components was examined after adjusting for age, sex, ethnicity, and BMI. RESULTS:Participants in the highest sedentary time tertile had significantly higher odds of MetS (OR=1.54) (95% CI 1.13 to 2.11) in comparison with participants in the lowest tertile (p=0.03). Participants in the highest sedentary time tertile had larger waist circumference (p=0.0001) and lower HDL-C (p=0.0003) than participants in the lowest sedentary time tertile. CONCLUSIONS:Sedentary time was strongly related to higher odds of MetS. These results, based on objectively measured sedentary time, suggest that sedentary time may represent an important risk factor for the development of MetS in older adults with high likelihood for disability.
journal_name
Exp Gerontoljournal_title
Experimental gerontologyauthors
Mankowski RT,Aubertin-Leheudre M,Beavers DP,Botoseneanu A,Buford TW,Church T,Glynn NW,King AC,Liu C,Manini TM,Marsh AP,McDermott M,Nocera JR,Pahor M,Strotmeyer ES,Anton SD,LIFE Research Group.doi
10.1016/j.exger.2015.06.018subject
Has Abstractpub_date
2015-10-01 00:00:00pages
32-6eissn
0531-5565issn
1873-6815pii
S0531-5565(15)30004-8journal_volume
70pub_type
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