Analysis of statistical biases in studies used to formulate guidelines: the case of arrhythmogenic right ventricular cardiomyopathy (ARVC) the case of ARVC.

Abstract:

RATIONALE AND OBJECTIVES:To analyze the statistical biases in the studies used to derive cardiac magnetic resonance-based major and minor criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC). MATERIALS AND METHODS:ARVC is a rare disorder of the heart that can lead to sudden death in young adults. Cardiac magnetic resonance imaging (CMR) plays a role in the diagnosis by contributing to the criteria set by experts. The original criteria emphasized qualitative analysis of CMR. The criteria were modified in 2010 to provide quantitative cutoffs. RESULTS:We apply the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool for systematic review of diagnostic accuracy to the studies cited in the guidelines written in 1994 and revised in 2010. We use the signaling questions in QUADAS-2 to identify different types of statistical bias. CONCLUSIONS:The studies have understandable biases that affect the sensitivity and specificity of CMR in the diagnosis of ARVC, as well as the truth of the disease state. There is potential to overdiagnose ARVC particularly in low prevalence populations.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Cook TS,Zimmerman SL,Jha S

doi

10.1016/j.acra.2015.04.009

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

1010-5

issue

8

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(15)00214-7

journal_volume

22

pub_type

杂志文章
  • Prognostic Value of Atherosclerosis Progression for Prediction of Cardiovascular Events in Patients with Nonobstructive Coronary Artery Disease.

    abstract:RATIONALE AND OBJECTIVES:Coronary CT angiography (CCTA) is a noninvasive reliable cardiovascular imaging technology to assess coronary atherosclerosis progression. However, there is limited data available to investigate the relationship between the atherosclerosis progression and cardiovascular events in patients with ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.06.038

    authors: Gu H,Lu B,Gao Y,Hou Z,Yang S,Yuan X,Zhao S,Wang X

    更新日期:2020-10-22 00:00:00

  • Comparison Between Dual-Energy Computed Tomography and Ultrasound in the Diagnosis of Gout of Various Joints.

    abstract:RATIONALE AND OBJECTIVES:Dual-energy computed tomography (DECT) and ultrasound are both used to assess gouty arthritis. The present study was designed to compare the diagnostic accuracy of DECT and ultrasound in detecting monosodium urate (MSU) crystal deposition in various joints. MATERIALS AND METHODS:This study enr...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2015.08.010

    authors: Zhu L,Wu H,Wu X,Sun W,Zhang T,Ye L,Wang W,Wang J

    更新日期:2015-12-01 00:00:00

  • Lung Mass in Smokers.

    abstract:RATIONALE AND OBJECTIVE:Emphysema is characterized by airspace dilation, inflammation, and irregular deposition of elastin and collagen in the interstitium. Computed tomographic studies have reported that lung mass (LM) may be increased in smokers, a finding attributed to inflammatory and parenchymal remodeling process...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2016.10.011

    authors: Washko GR,Kinney GL,Ross JC,San José Estépar R,Han MK,Dransfield MT,Kim V,Hatabu H,Come CE,Bowler RP,Silverman EK,Crapo J,Lynch DA,Hokanson J,Diaz AA,COPDGene Investigators.

    更新日期:2017-04-01 00:00:00

  • Cone beam CT in assessment of tibial bone defect healing: an animal study.

    abstract:RATIONALE AND OBJECTIVES:To evaluate cone beam computed tomography (CBCT) for monitoring of tibial bone defect healing in comparison to histopathological findings. MATERIALS AND METHODS:Circumscribed tibial bone defects were created in 16 mini-pigs and imaging of the tibia was performed on day 42 using a modern CBCT s...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.10.022

    authors: Kröpil P,Hakimi AR,Jungbluth P,Riegger C,Rubbert C,Miese F,Lanzman RS,Wild M,Schek A,Scherer A,Windolf J,Antoch G,Becker J,Hakimi M

    更新日期:2012-03-01 00:00:00

  • Female Representation on Radiology Journal Editorial Boards Around the World: Geographical Differences and Temporal Trends.

    abstract:RATIONALE AND OBJECTIVES:We examined the status of women's representation on radiology journal editorial boards around the world and evaluated temporal trends in female board representation. MATERIALS AND METHODS:Data on the gender of editorial board members, deputy editors, and editors-in-chief of top general radiolo...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.07.004

    authors: Joshi A,Kong W,Yu S,Balasubramanian S,Jankharia B,Agarwal PP

    更新日期:2020-08-08 00:00:00

  • Nephrogenic systemic fibrosis and management of high-risk patients.

    abstract::The purpose of this work is to provide current information on the rapidly evolving subject of nephrogenic systemic fibrosis (NSF), to establish the radiologic approach to the management of high-risk patients for NSF, and to assess the probabilistic risk of NSF compared to contrast induced nephropathy (CIN), as encount...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2009.01.001

    authors: Altun E,Semelka RC,Cakit C

    更新日期:2009-07-01 00:00:00

  • CT angiography with gadolinium-based contrast media.

    abstract:RATIONALE AND OBJECTIVES:To evaluate the potential use of gadolinium (Gd)-based contrast media, especially that of Gadovist, a 1-molar Gd medium, in computed tomography (CT) and compare our findings with standard iodinated contrast media. MATERIAL AND METHODS:Using a live rabbit and an acrylic CT body phantom for comp...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2006.03.019

    authors: Bonvento MJ,Moore WH,Button TM,Weinmann HJ,Yakupov R,Dilmanian FA

    更新日期:2006-08-01 00:00:00

  • Computer-aided detection of clustered microcalcifications in digitized mammograms.

    abstract:RATIONALE AND OBJECTIVES:We investigated a computer-aided detection (CAD) scheme for clustered microcalcifications in digitized mammograms. METHODS:A multistage CAD scheme was developed and tested. To increase sensitivity, the scheme uses a Gaussian band-pass filter and nonlinear threshold. A multistage local minimum ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80431-3

    authors: Zheng B,Chang YH,Staiger M,Good W,Gur D

    更新日期:1995-08-01 00:00:00

  • The Clinical Impact of Resident-attending Discrepancies in On-call Radiology Reporting: A Retrospective Assessment.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study is to quantify the clinical impact of resident-attending discrepancies at a tertiary referral academic radiology residency program by assessing rates of intervention, discrepancy confirmation, recall rate, and management change rate; furthermore, a discrepancy categori...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2017.11.016

    authors: McWilliams SR,Smith C,Oweis Y,Mawad K,Raptis C,Mellnick V

    更新日期:2018-06-01 00:00:00

  • Continuous quality improvement for radiologists.

    abstract::Continuous quality improvement methods provide a relatively new way to improve quality in healthcare by using a systems approach with key features of customer-mindedness, data collection, experimentation, and teamwork. CQI is not meant to solve simple problems but is increasingly applied in our complex healthcare orga...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/s1076-6332(03)00670-6

    authors: Applegate KE

    更新日期:2004-02-01 00:00:00

  • Machine classification of dental images with visual search.

    abstract:RATIONALE AND OBJECTIVES:The authors performed this study to assess the performance of a computer-based classification system that uses gaze locations of observers to define the subspace for machine learning. MATERIALS AND METHODS:Thirty-two dental radiographs were classified by an expert viewer into four categories o...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/S1076-6332(03)80706-7

    authors: Carmody DP,McGrath SP,Dunn SM,van der Stelt PF,Schouten E

    更新日期:2001-12-01 00:00:00

  • Addition of the Fleischner Society Guidelines to Chest CT Examination Interpretive Reports Improves Adherence to Recommended Follow-up Care for Incidental Pulmonary Nodules.

    abstract:RATIONALE AND OBJECTIVES:The study aimed to determine whether the addition of the Fleischner Society guidelines to chest computed tomography (CT) reports identifying incidental pulmonary nodules affects follow-up care. PATIENTS AND METHODS:Beginning in 2008, a template containing the Fleischner Society guidelines was ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2016.08.026

    authors: McDonald JS,Koo CW,White D,Hartman TE,Bender CE,Sykes AG

    更新日期:2017-03-01 00:00:00

  • Longitudinal follow-up comparison of educational interventions: multimedia textbook, traditional lecture, and printed textbook.

    abstract:RATIONALE AND OBJECTIVES:The goal of this prospective, interinstitutional study was to compare the long-term instructional effectiveness of a pediatric multimedia textbook (MMTB) to that of a standard lecture and a printed textbook. MATERIALS AND METHODS:A randomized cohort of 89 3rd-year medical students from two ins...

    journal_title:Academic radiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1076-6332(97)80074-8

    authors: D'Alessandro DM,Kreiter CD,Erkonen WE,Winter RJ,Knapp HR

    更新日期:1997-11-01 00:00:00

  • Use of serial FDG PET to measure the response of bone-dominant breast cancer to therapy.

    abstract:RATIONALE AND OBJECTIVES:The authors performed this study to determine the feasibility of using quantitative 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) to monitor the response of breast cancer bone metastases to therapy. MATERIALS AND METHODS:Twenty-four women with stage IV bone-d...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80461-0

    authors: Stafford SE,Gralow JR,Schubert EK,Rinn KJ,Dunnwald LK,Livingston RB,Mankoff DA

    更新日期:2002-08-01 00:00:00

  • Full field digital mammography and breast density: comparison of calibrated and noncalibrated measurements.

    abstract:RATIONALE AND OBJECTIVES:Mammographic breast density is an important and widely accepted risk factor for breast cancer. A statement about breast density in the mammographic report is becoming a requirement in many States. However, there is significant inter-observer variation between radiologists in their interpretatio...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.07.011

    authors: Heine JJ,Fowler EE,Flowers CI

    更新日期:2011-11-01 00:00:00

  • Breast DCE-MRI: influence of postcontrast timing on automated lesion kinetics assessments and discrimination of benign and malignant lesions.

    abstract:RATIONALE AND OBJECTIVES:Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) scanning protocols vary widely. The purpose of this study was to determine the effects of postcontrast timing on delayed-phase lesion kinetics assessment and ability to discriminate malignant from benign lesions. MATERIALS A...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2014.04.013

    authors: Partridge SC,Stone KM,Strigel RM,DeMartini WB,Peacock S,Lehman CD

    更新日期:2014-09-01 00:00:00

  • Mild traumatic brain injury: tissue texture analysis correlated to neuropsychological and DTI findings.

    abstract:RATIONALE AND OBJECTIVES:The aim of this study was to evaluate whether texture analysis (TA) can detect subtle changes in cerebral tissue caused by mild traumatic brain injury (MTBI) and to determine whether these changes correlate with neuropsychological and diffusion tensor imaging (DTI) findings. MATERIALS AND METH...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2010.04.009

    authors: Holli KK,Wäljas M,Harrison L,Liimatainen S,Luukkaala T,Ryymin P,Eskola H,Soimakallio S,Ohman J,Dastidar P

    更新日期:2010-09-01 00:00:00

  • Gain in signal-to-noise for first-pass contrast-enhanced abdominal MR angiography at 3 Tesla over standard 1.5 Tesla: prediction with a computer model.

    abstract:RATIONALE AND OBJECTIVES:To estimate the gain in signal-to-noise ratio (SNR) in first-pass contrast-enhanced (CE) abdominal magnetic resonance angiography (MRA) at 3.0 T compared with 1.5 T. MATERIALS AND METHODS:Three protocols were simulated using six contrast agents: gadopentetate dimeglumine (Magnevist, Berlex, Wa...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2007.03.007

    authors: Merkle EM,Dale BM,Barboriak DP

    更新日期:2007-07-01 00:00:00

  • Searching for nodules: what features attract attention and influence detection?

    abstract:RATIONALE AND OBJECTIVES:The goal of the study was to determine whether there are certain physical features of pulmonary nodules that attract visual attention and contribute to increased recognition and detection by observers. MATERIALS AND METHODS:A series of posteroanterior chest images with solitary pulmonary nodul...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)00055-2

    authors: Krupinski EA,Berger WG,Dallas WJ,Roehrig H

    更新日期:2003-08-01 00:00:00

  • A dedicated general competencies curriculum for radiology residents development and implementation.

    abstract:RATIONALE AND OBJECTIVES:The Accreditation Council on Graduate Medical Education (ACGME) through its Outcome Project requires training programs in all medical specialties to integrate six general competencies into residency training: patient care, medical knowledge, professionalism, interpersonal and communication skil...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2010.12.016

    authors: Relyea-Chew A,Talner LB

    更新日期:2011-05-01 00:00:00

  • Intraluminal air within an obstructed appendix: a CT sign of perforated or necrotic appendicitis.

    abstract:RATIONALE AND OBJECTIVES:The aim of this study was to evaluate the predictive value of intraluminal air for appendiceal necrosis and/or perforation when not apparent on imaging. Additional factors of intraluminal appendicoliths, age, and gender were also assessed. MATERIALS AND METHODS:Patients with pathologically pro...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.04.018

    authors: Azok JT,Kim DH,Munoz Del Rio A,Sonavane SK,Bhalla S,Anaya-Baez V,Menias CO

    更新日期:2012-10-01 00:00:00

  • New assistive devices for MR-guided microwave thermocoagulation of liver tumors.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to develop and test new assistive devices to aid in the performance of safe, easy, and accurate microwave thermocoagulation therapy guided by magnetic resonance (MR) imaging. MATERIALS AND METHODS:An open-configuration MR imager with an optical tracking system for...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80043-0

    authors: Morikawa S,Inubushi T,Kurumi Y,Naka S,Sato K,Tani T,Haque HA,Tokuda J,Hata N

    更新日期:2003-02-01 00:00:00

  • Marking of small pulmonary nodules before thoracoscopic resection: injection of lipiodol under CT-fluoroscopic guidance.

    abstract:RATIONALE AND OBJECTIVES:The aim of the present study was to examine the usefulness and record the complications of preoperative lipiodol marking using computed tomographic (CT) fluoroscopy for the intraoperative localization of 107 pulmonary nodules. METHODS:Lipiodol marking was performed under CT fluoroscopic guidan...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2008.07.012

    authors: Kawanaka K,Nomori H,Mori T,Ikeda K,Ikeda O,Tomiguchi S,Yamashita Y

    更新日期:2009-01-01 00:00:00

  • Diagnostic Performance of MR Imaging-based Features and Texture Analysis in the Differential Diagnosis of Ovarian Thecomas/Fibrothecomas and Uterine Fibroids in the Adnexal Area.

    abstract:RATIONALE AND OBJECTIVES:To investigate the value of MRI-based features and texture analysis (TA) in the differential diagnosis between ovarian thecomas/fibrothecomas (OTCA/f-TCAs) and uterine fibroids in the adnexal area (UF-iaas). MATERIALS AND METHODS:This retrospective study included 16 OTCA/f-TCA and 37 UF-iaa pa...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.12.025

    authors: Wei C,Chen YL,Li XX,Li NY,Wu YY,Lin TT,Wang CB,Zhang P,Dong JN,Yu YQ

    更新日期:2020-10-01 00:00:00

  • Robust, standardized quantification of pulmonary emphysema in low dose CT exams.

    abstract:RATIONALE AND OBJECTIVES:The aim of this study was to present and evaluate a fully automated system for emphysema quantification on low-dose computed tomographic images. The platform standardizes emphysema measurements against changes in the reconstruction algorithm and slice thickness. MATERIALS AND METHODS:Emphysema...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.06.015

    authors: Ceresa M,Bastarrika G,de Torres JP,Montuenga LM,Zulueta JJ,Ortiz-de-Solorzano C,Muñoz-Barrutia A

    更新日期:2011-11-01 00:00:00

  • Asymmetry analysis in rodent cerebral ischemia models.

    abstract:RATIONALE AND OBJECTIVES:An automated method for identification and segmentation of acute/subacute ischemic stroke, using the inherent bi-fold symmetry in brain images, is presented. An accurate and automated method for localization of acute ischemic stroke could provide physicians with a mechanism for early detection ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2008.03.013

    authors: Liu SX,Imielinska C,Laine A,Millar WS,Connolly ES,D'Ambrosio AL

    更新日期:2008-09-01 00:00:00

  • Virtual Read-Out: Radiology Education for the 21st Century During the COVID-19 Pandemic.

    abstract::Technologic advances have resulted in the expansion of web-based conferencing and education. While historically video-conferencing has been used for didactic educational sessions, we present its novel use in virtual radiology read-outs in the face of the COVID-19 pandemic. Knowledge of key aspects of set-up, implement...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.04.028

    authors: Li CH,Rajamohan AG,Acharya PT,Liu CJ,Patel V,Go JL,Kim PE,Acharya J

    更新日期:2020-06-01 00:00:00

  • Effect of team training on patients' ability to complete MRI examinations.

    abstract:RATIONALE AND OBJECTIVES:Assess whether staff training in advanced rapport skills and self-hypnotic relaxation techniques reduces noncompletion rates during magnetic resonance imaging (MRI). METHODS AND MATERIALS:All staff of a free-standing MRI facility was invited to 3 hours of preparatory communication lectures. Ha...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2009.07.002

    authors: Lang EV,Ward C,Laser E

    更新日期:2010-01-01 00:00:00

  • Selection of subtle cases for observer-performance studies: the importance of knowing the true diagnosis.

    abstract:RATIONALE AND OBJECTIVES:To assess the usefulness of classifying degree of difficulty in abnormality detection and to determine the effect of knowing the true diagnosis when selecting subtle images for observer-performance studies. MATERIALS AND METHODS:A total of 529 posteroanterior chest images that had been used in...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(98)80127-x

    authors: Rockette HE,King JL,Thaete FL,Fuhrman CR,Slifko RM,Gur D

    更新日期:1998-02-01 00:00:00

  • ABR Core examination preparation: results of a survey of fourth-year radiology residents who took the 2013 examination.

    abstract:RATIONALE AND OBJECTIVES:A survey was administered to fourth-year radiology residents after receiving their results from the first American Board of Radiology (ABR) Core examination in 2013. The purpose was to gather information regarding resources and study strategies to share with program directors and future residen...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2014.07.026

    authors: Shetty AS,Grajo JR,Decker S,Heitkamp DE,DeStigter KK,Mezwa DG,Deitte L

    更新日期:2015-01-01 00:00:00