Exogenous expression of IL-1Ra and TGF-β1 promotes in vivo repair in experimental rabbit osteoarthritis.

abstract：OBJECTIVE:Infectious brain lesions (IBLs) are life-threatening in patients with systemic lupus erythematosus (SLE). The aim of this study was to determine the prevalence of IBL in SLE patients and the clinical characteristics of SLE patients with IBL. METHODS:Medical charts of 15 consecutive SLE patients with IBL admi...

journal_title：Scandinavian journal of rheumatology

authors： Xu Y,Xu D,Zhang T,Leng XM,Zhang FC,Zeng XF

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:FURIN is a proprotein convertase enzyme that inhibits the proinflammatory function of T cells and myeloid cells. Elevated FURIN expression levels have been reported in immune-mediated diseases, such as primary Sjögren's syndrome. Here, we investigated the levels of FURIN in peripheral blood (PB) and synovial ...

journal_title：Scandinavian journal of rheumatology

authors： Valli A,Ranta N,Grönholm A,Silvennoinen O,Pesu M,Isomäki P

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of adalimumab, etanercept, and infliximab in patients with established rheumatoid arthritis (RA) taking concomitant methotrexate (MTX) by calculating the number needed to treat (NNT) using three different methods. METHODS:A systematic literature search of the Cochrane Library, MEDLINE...

journal_title：Scandinavian journal of rheumatology

authors： Kristensen LE,Christensen R,Bliddal H,Geborek P,Danneskiold-Samsøe B,Saxne T

更新日期：2007-11-01 00:00:00

abstract：:The subclass distribution of IgG and IgA plasma cells, and in IgG and IgA rheumatoid factor (RF) producing cells was studied in sections of synovial tissue from seropositive RA and various types of seronegative arthritis, including ankylosing spondylitis, psoriatic arthritis, and Reiter's syndrome. The study was perfo...

journal_title：Scandinavian journal of rheumatology

authors： Mellbye OJ,Vartdal F,Pahle J,Mollnes TE

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of interstitial lung disease (ILD) in patients with different forms of connective tissue disease (CTD) using non-invasive procedures including high-resolution computed tomography (HRCT) and to evaluate the relationship between the imaging and functional status of the patients. METHO...

journal_title：Scandinavian journal of rheumatology

authors： Afeltra A,Zennaro D,Garzia P,Gigante A,Vadacca M,Ruggiero A,Dardes N,Navajas MF,Zobel BB,Amoroso A

更新日期：2006-09-01 00:00:00

abstract：:Patients with post-venereal Reiter's syndrome, living in the districts of Egedesminde and Jakobshavn in Greenland, were ascertained from medical records and patient examinations. Fifty-one patients were found to have definite Reiter's syndrome according to the ARA proposed criteria. The prevalence of the disease is 1....

journal_title：Scandinavian journal of rheumatology

authors： Bardin T,Enel C,Lathrop M,Becker-Christensen F

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Chronic renal disease other than scleroderma renal crisis (SRC) is not well documented in systemic sclerosis (SSc). We examined the occurrence of decreased glomerular filtration rate (GFR) in a large consecutive SSc cohort and analysed whether it was related to SSc or could be related to other causes. METHOD...

journal_title：Scandinavian journal of rheumatology

authors： Scheja A,Bartosik I,Wuttge DM,Hesselstrand R

更新日期：2009-01-01 00:00:00

abstract：:Biopsy specimens of human articular cartilage were taken from the caudal summits and from the posterior part of both epicondyles of the right lower femoral epiphysis of 20 individuals within 12 hours post mortem. 12 articular surfaces were normal and 8 included changes attributable to osteoarthrosis. In one individual...

journal_title：Scandinavian journal of rheumatology

authors： Bjelle A

更新日期：1977-01-01 00:00:00

abstract：:In 9 patients with active rheumatoid arthritis we studied gastrointestinal blood loss during well tolerated therapy with the non-steroidal anti-inflammatory drug naproxen, 500 mg twice daily. The mean gastrointestinal blood loss, assessed with reinfused autologous 51Cr-labelled erythrocytes, was 1.4 +/- 0.6 ml/day (me...

journal_title：Scandinavian journal of rheumatology

authors： van den Ouweland FA,Corstens FH,van de Putte LB,Gribnau FW

更新日期：1987-01-01 00:00:00

abstract：:The distribution of messenger RNA coding for substance P receptor (NK1) in rheumatoid synovia and the relationship between signal intensity of NK1 mRNA and clinical parameters of disease activity were investigated. The synovia from 10 patients with rheumatoid arthritis (RA) and 7 patients with osteoarthritis was inves...

journal_title：Scandinavian journal of rheumatology

authors： Sakai K,Matsuno H,Tsuji H,Tohyama M

更新日期：1998-01-01 00:00:00

abstract：:To study the symptoms of NSAID-associated gastroduodenal bleeding, 94 patients (median age 71 years, range 19-90), were included in a prospective, clinical trial where hematemesis or melena from gastroduodenal ulceration or haemorrhagic/erosive gastritis were the inclusion criteria. NSAID use within one month was stud...

journal_title：Scandinavian journal of rheumatology

authors： Aabakken L,Weberg R,Lygren I,Eidsvoll B,Stray N,Osnes M

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Progressive destruction of synovial joint cartilage and bone occurs in pathological conditions such as rheumatoid arthritis (RA) because of the overproduction of pro-inflammatory cytokines and activation of nuclear factor kappa B (NF-κB). Through the screening of NF-κB inhibitors by a luciferase reporter gen...

journal_title：Scandinavian journal of rheumatology

authors： Liu Q,Zhao J,Tan R,Zhou H,Lin Z,Zheng M,Romas E,Xu J,Sims NA

更新日期：2015-05-01 00:00:00

abstract：:With improved disease survival, arterial thromboembolism has become an important cause of morbidity in patients with systemic lupus erythematosus (SLE). A number of conventional and non-conventional risk factors are associated with accelerated atherosclerosis. Regular surveillance and control of traditional risk facto...

journal_title：Scandinavian journal of rheumatology

authors： Mok CC

更新日期：2006-03-01 00:00:00

abstract：:We evaluated the efficacy and toxicity of cyclosporine A (CsA) in combination with methotrexate (MTX) or hydroxychloroquine (HCQ) in patients with refractory rheumatoid arthritis (RA). Fourteen patients with active RA who had failed to respond adequately to injectable MTX and 14 who had failed to respond to oral HCQ h...

journal_title：Scandinavian journal of rheumatology

authors： Salaffi F,Carotti M,Cervini C

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:In 2010, the American College of Rheumatology (ACR) proposed new criteria for the diagnosis of fibromyalgia (FM) in the context of objections to components of the criteria of 1990. The new criteria consider the Widespread Pain Index (WPI) and the Symptom Severity Score (SSS). This study evaluated the implica...

journal_title：Scandinavian journal of rheumatology

authors： Egloff N,von Känel R,Müller V,Egle UT,Kokinogenis G,Lederbogen S,Durrer B,Stauber S

更新日期：2015-01-01 00:00:00

abstract：:Levels of cyclic adenosine 3',5'-monophosphate (cAMP) and cyclic guanosine 3',5'-monophosphate (cGMP) have been investigated in joint fluid in inflammatory arthropathies. A disturbed balance between cAMP and cGMP due to a depressed level of cAMP was found in rheumatoid arthritis (RA) and Reiter's syndrome, in comparis...

journal_title：Scandinavian journal of rheumatology

authors： Trang LE,Lövgren O,Roch-Norlund AE,Horn RS,Walaas O

更新日期：1979-01-01 00:00:00

abstract：:The objective was to study the long-term effect (2 years) of different training programs in patients with rheumatoid arthritis. The method was a randomized trial with 75 patients participating. The measured variables included morning stiffness, a pain score, number of swollen joints, a health assessment score, a funct...

journal_title：Scandinavian journal of rheumatology

authors： Hansen TM,Hansen G,Langgaard AM,Rasmussen JO

更新日期：1993-01-01 00:00:00

abstract：:We studied HLA antigens in 105 unrelated American Caucasian patients with rheumatoid arthritis (RA), 70 of them with familial disease. HLA-DR4 was observed in 71% of familial RA, 63% of non-familial RA, and 27% of normal controls, confirming the already well-established association between HLA-DR4 and both familial an...

journal_title：Scandinavian journal of rheumatology

authors： Khan MA,Wolfe F,Kleinheksel SM,Molta C

更新日期：1987-01-01 00:00:00

abstract：:Rituximab is a genetically engineered chimeric monoclonal immunoglobulin (Ig)G1 antibody. It binds the CD20 trans-membrane surface antigen expressed by mature B cells but not by antibody secreting plasma cells, and removes the cells by activating complement, inducing cell-mediated lysis, and by apoptosis. Mainly used ...

journal_title：Scandinavian journal of rheumatology

authors： Omdal R,Wildhagen K,Hansen T,Gunnarsson R,Kristoffersen G

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:Platelets are thought to participate in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis (RA). We showed recently an in vivo increase in platelet-endothelial cell interactions in mice with antigen-induced arthritis (AiA). The underlying mechanisms are not yet clear. The aim of th...

journal_title：Scandinavian journal of rheumatology

authors： Schmitt-Sody M,Metz P,Klose A,Gottschalk O,Zysk S,Hausdorf J,Veihelmann A,Jansson V

更新日期：2007-07-01 00:00:00

abstract：:Psychological and emotional status was assessed in 36 patients with systemic lupus erythematosus (SLE) with the General Health Questionnaire-30 (GHQ-30) and Minnesota Multiphasic Personality Inventory (MMPI) questionnaires. The two tests were found to measure different aspects of psychological functioning. More than 5...

journal_title：Scandinavian journal of rheumatology

authors： Waterloo K,Omdal R,Husby G,Mellgren SI

更新日期：1998-01-01 00:00:00

abstract：:106 women and 38 men suffering from definite or classical rheumatoid arthritis underwent a pulmonary function test. The results were correlated to the duration and various clinical activity parameters of the disease. Pulmonary diffusion capacity was found to be reduced compared with the predicted values (p less than 0...

journal_title：Scandinavian journal of rheumatology

authors： Oxholm P,Madsen EB,Manthorpe R,Rasmussen FV

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:To assess 12-month changes in nutritional status and quality of life (QoL) in systemic sclerosis (SSc) patients requiring home parenteral nutrition (HPN). METHOD:We conducted a retrospective, single-centre database analysis of SSc patients regarding a 12-month period of HPN at an interdisciplinary Universit...

journal_title：Scandinavian journal of rheumatology

authors： Stanga Z,Aeberhard C,Schärer P,Kocher A,Adler S,Villiger PM

更新日期：2016-01-01 00:00:00

abstract：:Corneal chrysiasis is a common consequence of parenteral chrysotherapy in patients affected by rheumatoid arthritis. Concerning the factors and conditions that could be determinant for the gold accumulation in the cornea, there are contradictory opinions. Total or weekly gold dose and its accumulation quota, and the f...

journal_title：Scandinavian journal of rheumatology

authors： Mathieu A,Pala R,Carta S,Orzalesi N,Balestrieri A

更新日期：1985-01-01 00:00:00

abstract：:The changes in MR-determined synovial membrane volume, early synovial enhancement, and cartilage and bone erosions after osmic acid knee synovectomy were studied. Gadolinium-DTPA enhanced magnetic resonance imaging (MRI) of 18 knees with persistent arthritis was performed before and 1 month after treatment. The synovi...

journal_title：Scandinavian journal of rheumatology

authors： Ostergaard M,Stoltenberg M,Gideon P,Wieslander S,Sonne-Holm S,Kryger P,Sonne M

更新日期：1995-01-01 00:00:00

abstract：:'Arthroscopic volume' and resorption of normal saline was measured in 35 young males during routine arthroscopic examination. The average mean volume of the knee joint cavity was 103.4 ml and this volume was observed to correlate with the midpatellar circumference of the knee and the height of the patients. Mean resor...

journal_title：Scandinavian journal of rheumatology

authors： Visuri T,Kiviluoto O

更新日期：1986-01-01 00:00:00

abstract：:Four patients with systemic sclerosis (scleroderma) were treated with (D)-penicillamine (1.2-1.8 g/d) for 18-60 months. All patients improved. Vital capillary microscopy demonstrated that the number of visible skin capillaries increased during therapy, thus indicating a more efficient nutritional circulation. ...

journal_title：Scandinavian journal of rheumatology

authors： Mellstedt H,Fagrell B,Holm G,Björkholm M

更新日期：1977-01-01 00:00:00

abstract：:A case of gold-induced enterocolitis in a 69-year-old female with rheumatoid arthritis who had received the new gold compound by oral administration (Auranofin (AF) for 4 weeks) is reported. Mild diarrhoea is a commonly described side effect accompanying AF, but in this case a severe colitis developed. The course of t...

journal_title：Scandinavian journal of rheumatology

authors： Jarner D,Nielsen AM

更新日期：1983-01-01 00:00:00

abstract：:The initial evaluation of 25 patients suspected of suffering from Sjögren's syndrome (SS) disclosed that sialopenia and glandular atrophy without focal sialo-adenitis was the second most common cause, after SS itself, of patient complaints. This emphasizes the importance of conclusive diagnostic criteria to prevent ov...

journal_title：Scandinavian journal of rheumatology

authors： Malmström MJ,Segerberg-Konttinen M,Tuominen TS,Hietanen JH,Wolf JE,Sane JI,Konttinen YT

更新日期：1988-01-01 00:00:00

abstract：:Sixty-eight patients with giant cell arteritis (GCA) are described. In 42, histological evidence of arteritis was recorded at biopsy of a temporal artery. Twenty-six patients were included according to clinical criteria. In 20 patients the onset of illness was associated with an infection. The first symptom was: in 30...

journal_title：Scandinavian journal of rheumatology

authors： Malmvall BE,Bengtsson BA

更新日期：1978-01-01 00:00:00