Abstract:
OBJECTIVE:The consumption of hyperlipidic diets has grown markedly in recent decades, and several studies have linked this consumption with the development of neurodegenerative diseases. Conversely, hyperlipidic diets have been used as an alternative therapy for refractory epilepsy. The purpose of this study was to evaluate the effects of a hyperlipidic diet on brain electrical activity before and during status epilepticus (SE) using computational and mathematical methods. METHODS:Electrocorticogram (ECoG) was recorded in Wistar rats fed with standard and hyperlipidic diets. Each recording was obtained during 30-minute period (baseline), after this time, the SE was induced by pilocarpine, and recording was continued for another 30 minutes. The ECoG signals were analyzed by the following methods: power spectrum, Lempel-Ziv complexity (LZC), and fractal dimension of the phase space. RESULTS:Hyperlipidic diet in normal animals caused a decrease in the theta, alpha, and beta rhythm, and reduced the LZC of the brain electrical activity. However, when the animals were induced to SE, these differences between nutritional groups were not observed. SE caused in both dietary groups increase in theta, alpha, and beta rhythm values, and increase in the complexity of brain electrical activity. DISCUSSION:Hyperlipidic diet consumption attenuated the brain's electrical activity, suggesting that healthy individuals who habitually eat a hyperlipidic diet may develop dysfunctions such as cognitive decline and memory impairment. Furthermore, the antagonistic effect between hyperlipidic diet and SE suggests that this diet could protect against seizures.
journal_name
Nutr Neuroscijournal_title
Nutritional neuroscienceauthors
Pessoa D,Cruz R,Machado B,Tenorio B,Nogueira Rdoi
10.1179/1476830515Y.0000000033subject
Has Abstractpub_date
2016-06-01 00:00:00pages
206-12issue
5eissn
1028-415Xissn
1476-8305journal_volume
19pub_type
杂志文章abstract:OBJECTIVES:Genistein is a plant-derived estrogenic isoflavone commonly found in dietary and therapeutic supplements, due to its potential health benefits. Growth hormone-releasing hormone (GHRH) and somatostatin (SS) are neurosecretory peptides synthesized in neurons of the hypothalamus and regulate the growth hormone ...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830514Y.0000000143
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:The green seaweed Ulva sp. contains a large amount of ulvans, a family of sulphated polysaccharides. The present study was designed to investigate in rats the antidepressant- and anxiolytic-like effects of a hydrophilic extract of Ulva sp. (MSP) containing about 45% of ulvans. METHODS:After a 14-day adminis...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2016.1276704
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the nutritional status of children with SMA types II and III in a Chinese population. METHODS:We performed a retrospective medical record review of prospectively collected data from children with SMA types II and III in a single centre. We analysed data including clinical parameters, anthropometr...
journal_title:Nutritional neuroscience
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doi:10.1080/1028415X.2020.1871212
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830512Y.0000000048
更新日期:2013-09-01 00:00:00
abstract::Background and objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder for which no treatments exist. Fragile X syndrome (FXS) is the most common form of inherited mental retardation and the most frequent monogenic cause of ASD. Given the lack of pharmacological treatments for ASD, increasin...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2020.1819107
更新日期:2020-09-11 00:00:00
abstract::Objective: Possible effects of the vagus inhibition and stimulation on the hypothalamic nuclei, myenteric plexes and the vagus nerve were investigated. Methods: The female rats divided to the inhibition (INH), stimulation (STI) and, sham (SHAM) groups were fed with high fat diet (including 40% of energy from animal fa...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2020.1809875
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abstract::Insulin resistance is implicated in the pathophysiological changes associated with Alzheimer's disease, and pharmaceutical treatments that overcome insulin resistance improve memory function in subjects with mild cognitive impairment (MCI) and early Alzheimer's disease. Chromium (Cr) supplementation improves glucose d...
journal_title:Nutritional neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.1179/147683010X12611460764084
更新日期:2010-06-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.1179/1476830515Y.0000000023
更新日期:2016-11-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2016.1180859
更新日期:2017-10-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/147683009X423328
更新日期:2009-08-01 00:00:00
abstract::A debate is open in the literature concerning the safety of low (dietary) versus high (intoxicating or addicting) alcohol consumption. Epidemiological data do indeed suggest that moderate ethanol intake may have beneficial effects, at least at cardiovascular level. On the other hand there are few data on the effect of...
journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.1998.11747224
更新日期:1998-01-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
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更新日期:2019-01-01 00:00:00
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journal_title:Nutritional neuroscience
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doi:10.1080/1028415X.2018.1492772
更新日期:2020-03-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/147683010X12611460763481
更新日期:2010-02-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1179/1476830513Y.0000000094
更新日期:2014-11-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1707396
更新日期:2020-01-03 00:00:00
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journal_title:Nutritional neuroscience
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更新日期:2017-07-01 00:00:00
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journal_title:Nutritional neuroscience
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doi:10.1179/1476830511Y.0000000023
更新日期:2012-01-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
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journal_title:Nutritional neuroscience
pub_type: 信件
doi:10.1080/1028415X.2020.1728473
更新日期:2020-02-19 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.1998.11747231
更新日期:1998-01-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1423268
更新日期:2019-09-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2016.1203125
更新日期:2017-11-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1651105
更新日期:2019-08-09 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2017.1374033
更新日期:2019-04-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2018.1478653
更新日期:2020-02-01 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章
doi:10.1080/1028415X.2019.1660486
更新日期:2019-09-03 00:00:00
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journal_title:Nutritional neuroscience
pub_type: 杂志文章,评审
doi:10.1080/1028415X.2016.1236174
更新日期:2018-02-01 00:00:00