Abstract：
:A new compound, 1,4,5-trihydroxy-7-methoxy-9H-fluoren-9-one, has been isolated together with two known fluorenones, dendroflorin and denchrysan A, from the whole plant of Dendrobium chrysotoxum, a plant of Dendrobium genus, used as a health-food. The structure of the fluorenones has been determined on the basis of spectroscopic studies. The isolated compounds were evaluated in vitro for their inhibitory ability against the growth of human leukaemia cell lines K562 and HL-60, human lung adenocarcinoma A549, human hepatoma BEL-7402 and human stomach cancer SGC-7901. All three fluorenones displayed selective cytotoxicity against BEL-7402 with IC50 values of 1.49, 0.97 and 1.38μg/ml, respectively.
journal_name
Food Chemjournal_title
Food chemistryauthors
Chen Y,Li Y,Qing C,Zhang Y,Wang L,Liu Ydoi
10.1016/j.foodchem.2007.12.007subject
Has Abstractpub_date
2008-06-01 00:00:00pages
973-6issue
3eissn
0308-8146issn
1873-7072pii
S0308-8146(07)01263-0journal_volume
108pub_type
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