The Effect of Coumaric Acid on Ischemia-Reperfusion Injury of Sciatic Nerve in Rats.

abstract：:Psoriasis, a common skin inflammatory disorder, is characterized by the aberrant growth and differentiation of keratinocytes. Ar-Turmerone, a main bioactive ingredient of Curcuma longa, has been found to alleviate skin inflammation in psoriasis-like mice. However, the effects and underlying mechanism of ar-turmerone o...

journal_title：Inflammation

authors： Yang S,Liu J,Jiao J,Jiao L

更新日期：2020-04-01 00:00:00

abstract：:Human neutrophils were demonstrated to possess interleukin-2 receptor (IL-2R) beta and gamma chains, not alpha chain and the binding of IL-2 to the IL-2R beta chain on neutrophils plays an important regulatory role in neutrophil functions. We have investigated in this study the hypothesis that recombinant human IL-2 (...

journal_title：Inflammation

authors： Li J,Gyorffy S,Lee S,Kwok CS

更新日期：1996-08-01 00:00:00

abstract：:Recent studies have demonstrated that a calcium-sensitive protease converts Ca2+/phospholipid-dependent protein kinase C to a Ca2+/phospholipid-independent form during the activation of human neutrophils. In this paper, the results of the purification and characterization of a calcium-dependent cytosolic protease from...

journal_title：Inflammation

authors： Legendre JL,Jones HP

更新日期：1988-02-01 00:00:00

abstract：:Diets enriched in omega-3 fatty acids exert antiinflammatory properties by suppressing some neutrophil (PMN) functions. Changes in cytosolic Ca2+ concentration, [Ca2+]i, are important for PMN activation and are in part regulated by membrane Ca2+ ATPases. Since membrane proteins are influenced by their lipid environmen...

journal_title：Inflammation

authors： Georgilis K,Klempner MS

更新日期：1988-10-01 00:00:00

abstract：:Myeloperoxidase (MPO), next to the NO synthase2 (NOS2), and NADPH oxidase, is the key enzyme of the oxidative burst responsible for the antimicrobial immunity. Because MPO participates in the eradication of Mycobacterium tuberculosis in the in vitro model and the extracellular enzyme may activate cells to cytokine syn...

journal_title：Inflammation

authors： Koziol-Montewka M,Kolodziejek A,Oles J

更新日期：2004-04-01 00:00:00

abstract：:Praeruptorin C, D, and E (PC, PD, and PE) are three pyranocoumarins isolated from the dried root of Peucedanum praeruptorum Dunn of Umbelliferae. In the present study, we investigated the anti-inflammatory effect of these compounds in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophage cells. Pyranocoumarins signi...

journal_title：Inflammation

authors： Yu PJ,Jin H,Zhang JY,Wang GF,Li JR,Zhu ZG,Tian YX,Wu SY,Xu W,Zhang JJ,Wu SG

更新日期：2012-06-01 00:00:00

abstract：:The objective of this study was to determine nitric oxide (NO) and superoxide anion release (O-2) by neutrophils (PMNs) in the septic multiple organ dysfunction syndrome (MODS) and to compare them with the response of normal cells to lipopolysaccharide (LPS) and cytokines. NO production was measured by the release of ...

journal_title：Inflammation

authors： Carreras MC,Catz SD,Pargament GA,Del Bosco CG,Poderoso JJ

更新日期：1994-04-01 00:00:00

abstract：:Previous studies have suggested that Interleukin-6 (IL-6) acts as a marker of vasculitis. To determine the role of IL-6 in vasculitis we utilized two models of immune complex induced vascular injury (dermal Arthus and acute pulmonary alveolitis) in IL-6 deficient (IL-6(-/-)) and IL-6 sufficient (IL-6(+/+)) mice. Plasm...

journal_title：Inflammation

authors： McClintock SD,Barron AG,Olle EW,Deogracias MP,Warner RL,Opp M,Johnson KJ

更新日期：2005-12-01 00:00:00

abstract：:Dialysate and serum levels of granulocyte-colony stimulating factor (G-CSF), granulocyte macrophage colony stimulating factor (GM-CSF) and leukemia inhibitory factor (LIF) were analyzed in patients with continuous ambulatory peritoneal dialysis (CAPD). Samples from the peritoneal effluent and from serum were obtained ...

journal_title：Inflammation

authors： Brauner A,Hylander B,Lu Y

更新日期：1998-08-01 00:00:00

abstract：:We compared exhaled breath condensate (EBC) and induced sputum (IS) for assessing inflammation in pulmonary diseases in patients with obstructive lung disease (n = 20), persistent cough >6 months (n = 20), interstitial lung disease (n = 25) and controls (n = 10). EBC was collected by suspending a Teflon perfluoroalkox...

journal_title：Inflammation

authors： Fireman E,Shtark M,Priel IE,Shiner R,Mor R,Kivity S,Fireman Z

更新日期：2007-04-01 00:00:00

abstract：:D-limonene epoxidation generates (+)-limonene epoxide, an understudied compound in the pharmacologically point of view. Herein, we investigated the anti-inflammatory and antinociceptive potentialities of (+)-limonene epoxide and suggested a mechanism of action. The anti-inflammatory potential was analyzed using agents...

journal_title：Inflammation

authors： de Almeida AA,Silva RO,Nicolau LA,de Brito TV,de Sousa DP,Barbosa AL,de Freitas RM,Lopes LD,Medeiros JR,Ferreira PM

更新日期：2017-04-01 00:00:00

abstract：:Thromboxane (Tx) A2 generation and subsequent selective pulmonary sequestration of neutrophils (PMNs) is characteristic of several forms of the adult respiratory distress syndrome (ARDS). Therefore, we examined PMN-dependent adhesion to cultured pulmonary microvessel and aortic endothelium (EC) in response to U46,619 ...

journal_title：Inflammation

authors： Wiles ME,Welbourn R,Goldman G,Hechtman HB,Shepro D

更新日期：1991-06-01 00:00:00

abstract：:High-mobility group box 1 (HMGB1) plays a key role in the development of acute lung injury (ALI). Propofol, a general anesthetic with anti-inflammatory properties, has been suggested to be able to modulate lipopolysaccharide (LPS)-induced ALI. In this study, we investigated the effects of propofol on the expression of...

journal_title：Inflammation

authors： Wang X,Liu C,Wang G

更新日期：2016-06-01 00:00:00

abstract：:1-O-Alkyl-2-O-acetyl-sn-glycerol-3-phosphorylcholine (i.e., platelet-activating factor) was prepared and confirmed to possess potent platelet aggregating activity. It was also potent in aggregating and degranulating rabbit and human neutrophils. When injected into rabbits, the lipid induced profound neutropenia, throm...

journal_title：Inflammation

authors： O'Flaherty JT,Miller CH,Lewis JC,Wykle RL,Bass DA,McCall CE,Waite M,DeChatelet LR

更新日期：1981-09-01 00:00:00

abstract：:The present study was performed to explore the effect of aqueous extract of Aloe vera on behavioural parameters of pain. Pain assessment was performed by the tail-flick and formalin tests. A. vera (100 mg/kg, per oral (p.o.)) produced an insignificant decrease in the pain response in the tail-flick and formalin tests....

journal_title：Inflammation

authors： Rathor N,Mehta AK,Sharma AK,Mediratta PK,Sharma KK

更新日期：2012-12-01 00:00:00

abstract：:Our study showed that S-methylisothiourea (SMT) had anti-inflammatory effects in treating herpes simplex encephalitis in mice, and SMT also induced apoptosis of herpes simplex virus (HSV-1)-infected microglial cells. Both animal and cell models were employed in this study. Both models included the following five group...

journal_title：Inflammation

authors： Guo YJ,Li W,Li XF,Zhao L,Zhang SL,Zhou Y,Dong JH,Mei YW

更新日期：2011-10-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) with exogenous cassette DNA containing the methicillin-resistant gene mecA (SCCmec) poses a problem as a drug-resistant bacterium responsible for hospital- and community-acquired infections. The frequency of MRSA detection has recently been increasing rapidly in Japan...

journal_title：Inflammation

authors： Nihonyanagi S,Kanoh Y,Okada K,Uozumi T,Kazuyama Y,Yamaguchi T,Nakazaki N,Sakurai K,Hirata Y,Munekata S,Ohtani S,Takemoto T,Bandoh Y,Akahoshi T

更新日期：2012-06-01 00:00:00

abstract：:Polymorphonuclear neutrophil (PMN) function is thought to be critical in resistance to infectious agents and this implies that the PMN must be able to migrate into, and to function in, environments that may have high levels of bacterial lipopolysaccharide (LPS). Therefore, we have evaluated the effect of LPS on the in...

journal_title：Inflammation

authors： Creamer HR,Hunter N,Bullock WW,Gabler WL

更新日期：1991-06-01 00:00:00

abstract：:To investigate patients with severe acute pancreatitis (SAP) by dynamic levels of pro-/anti-inflammatory cytokines and endotoxin (ET) in plasma and the relationship between immunity and infection, organ dysfunction. Seventy-two patients with SAP were recruited. The ET, tumor necrosis factor-α (TNF-α), interleukin-6 (I...

journal_title：Inflammation

authors： Shen Y,Cui N,Miao B,Zhao E

更新日期：2011-02-01 00:00:00

abstract：:The aim of our study was to evaluate the pro- and anti-inflammatory cytokine response during acute pancreatitis and its predictive value on severity of disease. A hospital-based prospective clinical study was conducted. Twenty patients with acute pancreatitis were enrolled during a 12-month period. Plasma concentratio...

journal_title：Inflammation

authors： Gunjaca I,Zunic J,Gunjaca M,Kovac Z

更新日期：2012-04-01 00:00:00

abstract：:Calgranulins are small calcium-binding proteins with several immunological functions involved in inflammatory processes. Calgranulin A is reported to be mainly associated with acute inflammation while calgranulin B seems to play a role in chronic inflammatory disorders. In this study we used a proteomic approach to an...

journal_title：Inflammation

authors： Bargagli E,Olivieri C,Prasse A,Bianchi N,Magi B,Cianti R,Bini L,Rottoli P

更新日期：2008-10-01 00:00:00

abstract：:Exposure to ultraviolet (UV) light impairs the function of inflammatory cells. Urocanic acid (UCA) in an stratum corneum has been suggested as a mediator in the immunosuppression of lymphoid cells detected after irradiation with UVB (UV wavelengths 280-320 nm). In this study, we examined the effects of the two UCA iso...

journal_title：Inflammation

authors： Kivistö K,Punnonen K,Toppari J,Leino L

更新日期：1996-10-01 00:00:00

abstract：:The widely used mouse air pouch model of acute inflammation is inducible in a variety of inbred strains, but the potential influence of genetic background and gender on inflammation severity has never been examined. We directly compared the degree of inflammation induced in the air pouch model across four commonly uti...

journal_title：Inflammation

authors： Delano DL,Montesinos MC,D'Eustachio P,Wiltshire T,Cronstein BN

更新日期：2005-02-01 00:00:00

abstract：:In this study, we aimed to investigate the effect of electro-acupuncture (EA) pretreatment at zusanli (ST36) acupoint on lipopolysaccharide (LPS)-induced endotoxemic rat model and explore the underlying molecular mechanisms. Rats were treated with EA at ST36 for 7 days before being subjected to LPS. Two hours post-LPS...

journal_title：Inflammation

authors： Chen T,Xiong Y,Long M,Zheng D,Ke H,Xie J,Yin N,Chen Z

更新日期：2019-02-01 00:00:00

abstract：:Endothelial-neutrophil adhesion is a critical step in acute inflammatory diseases, which is mediated in part by P-selectin and platelet-activating factor (PAF). Nitric oxide (NO) is well known as an endogenous second messenger derived from endothelial cells, and regulates many important physiological events, however, ...

journal_title：Inflammation

authors： Okayama N,Coe L,Itoh M,Alexander JS

更新日期：1999-02-01 00:00:00

abstract：:Mastitis is a major disease in humans and other animals and is characterized by mammary gland inflammation. It is a major disease of the dairy industry. Bergenin is an active constituent of the plants of genus Bergenia. Research indicates that bergenin has multiple biological activities, including anti-inflammatory an...

journal_title：Inflammation

authors： Gao XJ,Guo MY,Zhang ZC,Wang TC,Cao YG,Zhang NS

更新日期：2015-01-01 00:00:00

abstract：:By the use of the nuclear microprobe technique, the concentrations of zinc in isolated erythrocytes, platelets, and granulocytes were measured in patients with rheumatoid arthritis, other inflammatory arthritides, and scleroderma. Markedly reduced cellular zinc values were found compared to those measured in healthy s...

journal_title：Inflammation

authors： Svenson KL,Hällgren R,Johansson E,Lindh U

更新日期：1985-06-01 00:00:00

abstract：:Enzyme-inducing drugs such as phenobarbital (PB) increase serum concentrations of an acute-phase protein, alpha 1-acid glycoprotein (AGP), in man, dogs, and rats via an unknown mechanism. We studied the effects of PB on components of an acute inflammatory reaction in rats in order to determine if PB acts only on this ...

journal_title：Inflammation

authors： Levy FE,Chauvelot-Moachon L,Florentin I,Forest M,Poüs C,Fournier C,Giroud JP

更新日期：1991-12-01 00:00:00

abstract：:Numerous cytokines, including vascular endothelial growth factor (VEGF), are implicated in the pathogenesis of sepsis. While overexpression of VEGF produces pulmonary capillary leak, the role of VEGF in sepsis is less clear. We investigated VEGF in sepsis, utilizing a VEGF trap (VEGF(T)). Polymicrobial sepsis was indu...

journal_title：Inflammation

authors： Nolan A,Weiden MD,Thurston G,Gold JA

更新日期：2004-10-01 00:00:00

abstract：:Acute lung injury (ALI) is a serious disease with morbidity and mortality in patients. Engeletin (dihydrokaempferol 3-rhamnoside) is a flavanonol glycoside. It can be found in the skin of white grapes and white wine and is widely distributed in southeast Asia. In our study, we evaluated the protective and therapeutic ...

journal_title：Inflammation

authors： Jiang X,Chen L,Zhang Z,Sun Y,Wang X,Wei J

更新日期：2018-08-01 00:00:00