The expanding spectrum of human infections caused by Kocuria species: a case report and literature review.

abstract：:GRP78/BiP is an endoplasmic reticulum (ER) chaperone protein with the important function of maintaining ER homeostasis, and the overexpression of GRP78/BiP alleviates ER stress. Our previous studies showed that infection with enterovirus 71 (EV71), a (+)RNA picornavirus, induced GRP78/BiP upregulation; however, ectopi...

journal_title：Emerging microbes & infections

authors： Jheng JR,Wang SC,Jheng CR,Horng JT

更新日期：2016-03-23 00:00:00

abstract：:In March 2013, a patient infected with a novel avian influenza A H7N9 virus was reported in China. Since then, there have been 458 confirmed infection cases and 177 deaths. The virus contains several human-adapted markers, indicating that H7N9 has pandemic potential. The outbreak of this new influenza virus highlighte...

journal_title：Emerging microbes & infections

authors： Leung HC,Chan CC,Poon VK,Zhao HJ,Cheung CY,Ng F,Huang JD,Zheng BJ

更新日期：2015-04-01 00:00:00

abstract：:Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses are not of immedia...

journal_title：Emerging microbes & infections

authors： Amanat F,Meade P,Strohmeier S,Krammer F

更新日期：2019-01-01 00:00:00

abstract：:Human papillomaviruses (HPV) contribute to most cervical cancers and are considered to be sexually transmitted. However, papillomaviruses are often found in cancers of internal organs, including the stomach, raising the question as to how the viruses gain access to these sites. A possible connection between blood tran...

journal_title：Emerging microbes & infections

authors： Cladel NM,Jiang P,Li JJ,Peng X,Cooper TK,Majerciak V,Balogh KK,Meyer TJ,Brendle SA,Budgeon LR,Shearer DA,Munden R,Cam M,Vallur R,Christensen ND,Zheng ZM,Hu J

更新日期：2019-01-01 00:00:00

abstract：:Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province of China. This host switch was followed by multiple reassortment events between these H1N1 and previously circul...

journal_title：Emerging microbes & infections

authors： Wang G,Dos Anjos Borges LG,Stadlbauer D,Ramos I,Bermúdez González MC,He J,Ding Y,Wei Z,Ouyang K,Huang W,Simon V,Fernandez-Sesma A,Krammer F,Nelson MI,Chen Y,García-Sastre A

更新日期：2019-01-01 00:00:00

abstract：:We report the discovery and confirmation of 23 novel mutations with previously undocumented role in isoniazid (INH) drug resistance, in catalase-peroxidase (katG) gene of Mycobacterium tuberculosis (Mtb) isolates. With these mutations, a synonymous mutation in fabG1 (g609a), and two canonical mutations, we were able t...

journal_title：Emerging microbes & infections

authors： Torres JN,Paul LV,Rodwell TC,Victor TC,Amallraja AM,Elghraoui A,Goodmanson AP,Ramirez-Busby SM,Chawla A,Zadorozhny V,Streicher EM,Sirgel FA,Catanzaro D,Rodrigues C,Gler MT,Crudu V,Catanzaro A,Valafar F

更新日期：2015-07-01 00:00:00

abstract：:Molecular epidemiology of Clostridium difficile infection (CDI) has been extensively studied in North America and Europe; however, limited data on CDI are available in the Asia-Pacific region. A multicentre retrospective study was conducted in this region. C. difficile isolates were subjected to multilocus sequence ty...

journal_title：Emerging microbes & infections

authors： Luo Y,Cheong E,Bian Q,Collins DA,Ye J,Shin JH,Yam WC,Takata T,Song X,Wang X,Kamboj M,Gottlieb T,Jiang J,Riley TV,Tang YW,Jin D

更新日期：2019-01-01 00:00:00

abstract：:Human enteroviruses frequently cause severe diseases in children. Human enteroviruses are transmitted via the fecal-oral route and respiratory droplets, and primary replication occurs in the gastro-intestinal and respiratory tracts; however, how enteroviruses infect these sites is largely unknown. Human intestinal org...

journal_title：Emerging microbes & infections

authors： van der Sanden SMG,Sachs N,Koekkoek SM,Koen G,Pajkrt D,Clevers H,Wolthers KC

更新日期：2018-05-09 00:00:00

abstract：:Histoplasmosis caused by the fungus Histoplasma capsulatum is often lethal in patients with AIDS. Urine antigen testing is highly sensitive and much quicker for diagnosis than culture. Histoplasmosis has a patchy and incompletely appreciated distribution around the world especially in South East Asia. We conducted a s...

journal_title：Emerging microbes & infections

authors： Baker J,Setianingrum F,Wahyuningsih R,Denning DW

更新日期：2019-01-01 00:00:00

abstract：:Saffold virus (SAFV), a newly discovered human cardiovirus of the Picornaviridae family, causes widespread infection among children, as shown by previous seroprevalence studies. To determine the host cell range of SAFV and its cytopathogenicity, eight mammalian cell lines that were available in the laboratory were scr...

journal_title：Emerging microbes & infections

authors： Xu Y,Victorio CB,Ng Q,Tan YJ,Chua KB

更新日期：2014-02-01 00:00:00

abstract：:Interferon-induced transmembrane protein 3 (IFITM3) as an antiviral factor can inhibit replication of several viruses including influenza virus. A single-nucleotide polymorphism rs12252-C of IFITM3 results in a truncated IFITM3 protein lacking its first 21 amino acids, which is much higher in the Han Chinese populatio...

journal_title：Emerging microbes & infections

authors： Lei N,Li Y,Sun Q,Lu J,Zhou J,Li Z,Liu L,Guo J,Qin K,Wang H,Zhao J,Li C,Sun L,Wang D,Zhao Z,Shu Y

更新日期：2020-12-01 00:00:00

abstract：:Accumulating evidence indicates that bacterial metabolism plays an important role in virulence. Acetyl phosphate (AcP), the high-energy intermediate of the phosphotransacetylase-acetate kinase pathway, is the major acetyl donor in E. coli. PhoP is an essential transcription factor for bacterial virulence. Here, we sho...

journal_title：Emerging microbes & infections

authors： Ren J,Sang Y,Qin R,Su Y,Cui Z,Mang Z,Li H,Lu S,Zhang J,Cheng S,Liu X,Li J,Lu J,Wu W,Zhao GP,Shao F,Yao YF

更新日期：2019-01-01 00:00:00

abstract：:Dengue virus (DENV) is a mosquito-borne Flavivirus that is endemic in many tropical and sub-tropical countries where the transmission vectors Aedes spp. mosquitoes resides. There are four serotypes of the virus. Each serotype is antigenically different, meaning they elicit heterologous antibodies. Infection with one s...

journal_title：Emerging microbes & infections

authors： Uno N,Ross TM

更新日期：2018-10-10 00:00:00

abstract：:Lentiviruses harbour high genetic variability for efficient evasion from host immunity. An attenuated equine infectious anaemia (EIA) vaccine was developed decades ago in China and presented remarkably robust protection against EIA. The vaccine was recently proven to have high genomic diversity, particular in env. How...

journal_title：Emerging microbes & infections

authors： Lin Y,Wang XF,Wang Y,Du C,Ren H,Liu C,Zhu D,Chen J,Na L,Liu D,Yang Z,Wang X

更新日期：2020-12-01 00:00:00

abstract：:Although a number of standardized human immunodeficiency virus 1 (HIV-1) pseudoviruses have been generated to assess neutralizing antibodies, subtype B/B' has not been comprehensively characterized either genotypically or phenotypically. Full-length env genes were isolated from plasma samples derived from B/B'-infecte...

journal_title：Emerging microbes & infections

authors： Xie H,Nie J,Chen Q,Huang W,Wang Y

更新日期：2018-05-16 00:00:00

abstract：:The first imported case of Middle East respiratory syndrome (MERS) in China recently occurred, allowing for the characterization of antibody titers in a series of the patient's sera using the following methods based on recombinant viral structural antigens: inactivated MERS coronavirus (MERS-CoV) enzyme-linked immunos...

journal_title：Emerging microbes & infections

authors： Wang W,Wang H,Deng Y,Song T,Lan J,Wu G,Ke C,Tan W

更新日期：2016-11-09 00:00:00

abstract：:Zika virus (ZIKV) has become a threat to global health since the outbreak in Brazil in 2015. Although ZIKV is generally considered an Aedes-transmitted pathogen, new evidence has shown that parts of the virus closely resemble Culex-transmitted viruses. Therefore, it is important to evaluate the competence of Culex spe...

journal_title：Emerging microbes & infections

authors： Guo XX,Li CX,Deng YQ,Xing D,Liu QM,Wu Q,Sun AJ,Dong YD,Cao WC,Qin CF,Zhao TY

更新日期：2016-09-07 00:00:00

abstract：:From September 2015 to March 2016, hepatitis A notifications in Germany increased by 45% to 699 cases compared to 482 cases in the same period of the previous year. Children aged five to nine years were predominantly affected (22% of all cases in this period). We hypothesized that this increase could be explained by t...

journal_title：Emerging microbes & infections

authors： Michaelis K,Wenzel JJ,Stark K,Faber M

更新日期：2017-04-26 00:00:00

abstract：:The progressive anthropization of caves for food resources or economic purposes increases human exposure to pathogens that naturally infect cave-dwelling animals. The presence of wild or domestic animals in the immediate surroundings of caves also may contribute to increasing the risk of emergence of such pathogens. S...

journal_title：Emerging microbes & infections

authors： Obame-Nkoghe J,Leroy EM,Paupy C

更新日期：2017-04-12 00:00:00

abstract：:Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, were isolated during a surveillance of pigs from private farms in Russia from 2016 to 2017. Ther...

journal_title：Emerging microbes & infections

authors： Sobolev I,Kurskaya O,Leonov S,Kabilov M,Alikina T,Alekseev A,Yushkov Y,Saito T,Uchida Y,Mine J,Shestopalov A,Sharshov K

更新日期：2019-01-01 00:00:00

abstract：:Zika virus (ZIKV) infection during pregnancy is associated with congenital brain abnormalities, a finding that highlights the urgent need to understand mother-to-fetus transmission mechanisms. Human umbilical cord mesenchymal stem cells (hUCMSCs) are susceptible to ZIKV infection but the underlying mechanisms of viral...

journal_title：Emerging microbes & infections

authors： Seong RK,Lee JK,Cho GJ,Kumar M,Shin OS

更新日期：2020-12-01 00:00:00

abstract：:Occult hepatitis B virus infection (OBI) is a low-level asymptomatic phase of HBV infection. Evidence of OBI clinical relevance is emerging but the mechanisms of its occurrence remain unclear. In this study, the molecular characteristics of 97 confirmed OBI from Chinese blood donors were analyzed and relevant mutation...

journal_title：Emerging microbes & infections

authors： Zhang L,Chang L,Laperche S,Ji H,Zhao J,Jiang X,Wang L,Candotti D

更新日期：2019-01-01 00:00:00

abstract：:Shiga toxin (Stx)-producing Escherichia coli (STEC) can cause a wide range of symptoms from asymptomatic carriage, mild diarrhea to bloody diarrhea (BD) and hemolytic uremic syndrome (HUS). Intimin, encoded by the eae gene, also plays a critical role in STEC pathogenesis. Herein, we investigated the prevalence and gen...

journal_title：Emerging microbes & infections

authors： Hua Y,Bai X,Zhang J,Jernberg C,Chromek M,Hansson S,Frykman A,Yang X,Xiong Y,Wan C,Matussek A

更新日期：2020-12-01 00:00:00

abstract：:Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens causing severe gastroenteritis, which may lead to hemolytic uremic syndrome. The Locus of Enterocyte Effacement (LEE), a Pathogenicity Island (PAI), is a major determinant of intestinal epithelium attachment of a group of STEC strains; however, the ...

journal_title：Emerging microbes & infections

authors： Montero DA,Canto FD,Velasco J,Colello R,Padola NL,Salazar JC,Martin CS,Oñate A,Blanco J,Rasko DA,Contreras C,Puente JL,Scheutz F,Franz E,Vidal RM

更新日期：2019-01-01 00:00:00

abstract：:Avian influenza A(H7N9) virus (A(H7N9)) emerged in February 2013. Liver impairment of unknown cause is present in 29% of patients with A(H7N9) infection, some of whom experience severe liver injury. Hypoxic hepatitis (HH) is a type of acute severe liver injury characterized by an abrupt, massive increase in serum amin...

journal_title：Emerging microbes & infections

authors： Zhang Y,Liu J,Yu L,Zhou N,Ding W,Zheng S,Shi D,Li L

更新日期：2016-01-06 00:00:00

abstract：:Nontuberculous mycobacterial (NTM) infections in humans have increased in prevalence in recent decades. Mycobacterium kansasii is one of the most prevalent human pathogenic NTM species worldwide. Herein, we report the first isolation of M. kansasii from an indoor domestic cat in Japan. Comparative genome sequence anal...

journal_title：Emerging microbes & infections

authors： Fukano H,Terazono T,Hirabayashi A,Yoshida M,Suzuki M,Wada S,Ishii N,Hoshino Y

更新日期：2021-01-19 00:00:00

abstract：:Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries represent up to 95% of recent clinical isolates. Knowledge on the effect...

journal_title：Emerging microbes & infections

authors： Hovingh ES,Mariman R,Solans L,Hijdra D,Hamstra HJ,Jongerius I,van Gent M,Mooi F,Locht C,Pinelli E

更新日期：2018-03-21 00:00:00

abstract：:Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In ...

journal_title：Emerging microbes & infections

authors： Jin W,Dong C

更新日期：2013-09-01 00:00:00

abstract：:A 78-year-old woman with a long-term ankle spacer with antibacterials developed an intra-articular Candida auris infection. Treatment with systemic antifungal therapy plus an amphotericin B moulded cement spacer was successful. ...

journal_title：Emerging microbes & infections

authors： Roberts SC,Zembower TR,Bolon MK,Kadakia AR,Gilley JH,Ko JH,Clark J,Ward-Fore S,Taiwo BO

更新日期：2019-01-01 00:00:00

abstract：:MERS-CoV infection emerged in the Kingdom of Saudi Arabia (KSA) in 2012 and has spread to 26 countries. However, 80% of all cases have occurred in KSA. The largest outbreak outside KSA occurred in South Korea (SK) in 2015. In this report, we describe an epidemiological comparison of the two outbreaks. Data from 1299 c...

journal_title：Emerging microbes & infections

authors： Chen X,Chughtai AA,Dyda A,MacIntyre CR

更新日期：2017-06-07 00:00:00