The GHSG Approach to Treating Hodgkin's Lymphoma.

Abstract:

:Hodgkin's lymphoma (HL) is a relatively rare disease accounting for 15 % of all lymphoma. This disease has developed from an incurable disease to the adult malignancy with the most favorable prognosis. With current therapeutic approaches consisting of polychemo- and small-field radiotherapy, up to 80 % of all patients can be cured long term. In refractory or relapsed HL, intensified treatment including high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) is associated with progression-free survival (PFS) of 50 %. Evaluation of novel drugs in multiple relapsed or refractory cases, better treatment options for elderly patients and reducing treatment-related side effects are the main focus of current research. Recent clinical developments and future approaches in the treatment of HL will be discussed in this review.

journal_name

Curr Hematol Malig Rep

authors

Bröckelmann PJ,Engert A

doi

10.1007/s11899-015-0262-5

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

256-65

issue

3

eissn

1558-8211

issn

1558-822X

journal_volume

10

pub_type

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