Modeling neural activity with cumulative damage distributions.

Abstract:

:Neurons transmit information as action potentials or spikes. Due to the inherent randomness of the inter-spike intervals (ISIs), probabilistic models are often used for their description. Cumulative damage (CD) distributions are a family of probabilistic models that has been widely considered for describing time-related cumulative processes. This family allows us to consider certain deterministic principles for modeling ISIs from a probabilistic viewpoint and to link its parameters to values with biological interpretation. The CD family includes the Birnbaum-Saunders and inverse Gaussian distributions, which possess distinctive properties and theoretical arguments useful for ISI description. We expand the use of CD distributions to the modeling of neural spiking behavior, mainly by testing the suitability of the Birnbaum-Saunders distribution, which has not been studied in the setting of neural activity. We validate this expansion with original experimental and simulated electrophysiological data.

journal_name

Biol Cybern

journal_title

Biological cybernetics

authors

Leiva V,Tejo M,Guiraud P,Schmachtenberg O,Orio P,Marmolejo-Ramos F

doi

10.1007/s00422-015-0651-9

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

421-33

issue

4-5

eissn

0340-1200

issn

1432-0770

pii

10.1007/s00422-015-0651-9

journal_volume

109

pub_type

杂志文章,评审
  • Invariant recognition of feature combinations in the visual system.

    abstract::The operation of a hierarchical competitive network model (VisNet) of invariance learning in the visual system is investigated to determine how this class of architecture can solve problems that require the spatial binding of features. First, we show that VisNet neurons can be trained to provide transform-invariant di...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220100284

    authors: Elliffe MC,Rolls ET,Stringer SM

    更新日期:2002-01-01 00:00:00

  • Bayesian models of eye movement selection with retinotopic maps.

    abstract::Among the various possible criteria guiding eye movement selection, we investigate the role of position uncertainty in the peripheral visual field. In particular, we suggest that, in everyday life situations of object tracking, eye movement selection probably includes a principle of reduction of uncertainty. To evalua...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-009-0292-y

    authors: Colas F,Flacher F,Tanner T,Bessière P,Girard B

    更新日期:2009-03-01 00:00:00

  • Computational nature of human adaptive control during learning of reaching movements in force fields.

    abstract::Learning to make reaching movements in force fields was used as a paradigm to explore the system architecture of the biological adaptive controller. We compared the performance of a number of candidate control systems that acted on a model of the neuromuscular system of the human arm and asked how well the dynamics of...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050543

    authors: Bhushan N,Shadmehr R

    更新日期:1999-07-01 00:00:00

  • Pattern separability in a random neural net with inhibitory connections.

    abstract::Some interesting properties on pattern separation have been shown through researches by neural models of cerebellar cortex. It seems to us that those results are a part of the properties of pattern separation. A two layer random nerve net with inhibitory connections is given as a model of the cerebellar cortex. The mo...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00336858

    authors: Torioka T

    更新日期:1979-09-01 00:00:00

  • Investigation of transmitter-receptor interactions by analyzing postsynaptic membrane noise using stochastic kinetics.

    abstract::The stoichiometric and kinetic details of transmitter-receptor interaction (the number of conformations and the rate constants of conformation changes( in synaptic transmission have been investigated analyzing postsynaptic membrane noises by the aid of the fluctuation-dissipation theorem of stochastic chemical kinetic...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00337450

    authors: Erdi P,Ropolyi L

    更新日期:1979-02-02 00:00:00

  • A posteriori time-varying filtering of averaged evoked potentials. II. Mathematical and computational aspects.

    abstract::The problem of estimating an unknown transient signal, given an ensemble of waveforms, in which this signal appears as a nonrandom component in the presence of additive noise is considered. This problem is solved by generalizing the method of "a posteriori 'Wiener' filtering". In the new method, the ensemble average i...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00340323

    authors: de Weerd JP,Kap JI

    更新日期:1981-01-01 00:00:00

  • A minimum energy cost hypothesis for human arm trajectories.

    abstract::Many tasks require the arm to move from its initial position to a specified target position, but leave us free to choose the trajectory between them. This paper presents and tests the hypothesis that trajectories are chosen to minimize metabolic energy costs. Costs are calculated for the range of possible trajectories...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050324

    authors: Alexander RM

    更新日期:1997-02-01 00:00:00

  • Dynamic updating of distributed neural representations using forward models.

    abstract::In this paper, we present a continuous attractor network model that we hypothesize will give some suggestion of the mechanisms underlying several neural processes such as velocity tuning to visual stimulus, sensory discrimination, sensorimotor transformations, motor control, motor imagery, and imitation. All of these ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-006-0131-3

    authors: Sauser EL,Billard AG

    更新日期:2006-12-01 00:00:00

  • Multi-loop representation of the segmental muscle stretch reflex. Its risk of instability.

    abstract::The multi-channel system of the segmental muscle stretch reflex arc is modelled as an arrangement of two or three parallel "component" loops coupled to each other at spinal and at muscle level. Such a model is thought to be more realistic than the usually adopted representation of the stretch reflex as a single negati...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00337401

    authors: Koehler W,Windhorst U

    更新日期:1980-01-01 00:00:00

  • Torque-stiffness-controlled dynamic walking with central pattern generators.

    abstract::Walking behavior is modulated by controlling joint torques in most existing passivity-based bipeds. Controlled Passive Walking with adaptable stiffness exhibits controllable natural motions and energy efficient gaits. In this paper, we propose torque-stiffness-controlled dynamic bipedal walking, which extends the conc...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-014-0625-3

    authors: Huang Y,Vanderborght B,Van Ham R,Wang Q

    更新日期:2014-12-01 00:00:00

  • Depth, contrast and view-based homing in outdoor scenes.

    abstract::Panoramic image differences can be used for view-based homing under natural outdoor conditions, because they increase smoothly with distance from a reference location (Zeil et al., J Opt Soc Am A 20(3):450-469, 2003). The particular shape, slope and depth of such image difference functions (IDFs) recorded at any one p...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-007-0147-3

    authors: Stürzl W,Zeil J

    更新日期:2007-05-01 00:00:00

  • On the respresentation of multi-input systems: computational properties of polynomial algorithms.

    abstract::This paper introduces a theoretical frame-work for characterizing and classifying simple parallel algorithms and systems with many inputs, for example an array of photoreceptors. The polynomial representation (Taylor series development) of a large class of operators is introduced and its range of validity discussed. T...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00355455

    authors: Poggio T,Reichardt W

    更新日期:1980-01-01 00:00:00

  • Topography of alpha and theta oscillatory responses upon auditory and visual stimuli in humans.

    abstract::Brain resonance phenomena and induced rhythms in the brain recently gained importance in electroencephalographic, magnetoencephalographic and cellular studies (Başar and Bullock 1992). It was hypothesized that evoked potentials are superpositions of induced rhythms caused by resonance phenomena in neural populations (...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00205980

    authors: Schürmann M,Başar E

    更新日期:1994-01-01 00:00:00

  • Contrast Discrimination by the human visual system.

    abstract::In vision of everyday scenes, features requiring detection are frequently observed in the presence of suprathreshold background structures. Detection of such features is a contrast discrimination task and is often necessary for the subsequent process of recognition. In order to provide a description of this task, cont...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00326678

    authors: Burton GJ

    更新日期:1981-01-01 00:00:00

  • Reduced order multiport parallel and multidirectional neural associative memories.

    abstract::This paper proposes multiport parallel and multidirectional intraconnected associative memories of outer product type with reduced interconnections. Some new reduced order memory architectures such as k-directional and k-port parallel memories are suggested. These architectures are, also, very suitable for implementat...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-009-0310-0

    authors: Bhatti AA

    更新日期:2009-05-01 00:00:00

  • A pacemaker cell pair model based on the phase response curve.

    abstract::A pacemaker cell pair model and the dynamic interaction between the two pacemaker cells is described in this paper. It is an extension of our single pacemaker cell model, in which we studied its response to repetitive external depolarization stimulations. This model is a simple model based on the two most important fu...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050460

    authors: Abramovich-Sivan S,Akselrod S

    更新日期:1998-07-01 00:00:00

  • Relevance of the single ommatidium performance in determining the oscillatory response of the Limulus retina.

    abstract::The response of a healthy lateral eye of Limulus to constant, uniform and sufficiently intense light stimulation, consists of a sustained oscillatory discharge, all ommatidia firing synchronously in bursts, at intervals of about 0.2s (Barlow and Fraioli, 1978). This response has been analysed by a computer simulation,...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00336944

    authors: Barbi M,Ferdeghini EM

    更新日期:1980-01-01 00:00:00

  • Hierarchical Bayesian models of cognitive development.

    abstract::This article provides an introductory overview of the state of research on Hierarchical Bayesian Modeling in cognitive development. First, a brief historical summary and a definition of hierarchies in Bayesian modeling are given. Subsequently, some model structures are described based on four examples in the literatur...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/s00422-016-0686-6

    authors: Glassen T,Nitsch V

    更新日期:2016-06-01 00:00:00

  • A dynamic model of thoracic differentiation for the control of turning in the stick insect.

    abstract::Leg movements of stick insects (Carausius morosus) making turns towards visual targets are examined in detail, and a dynamic model of this behaviour is proposed. Initial results suggest that front legs shape most of the body trajectory, while the middle and hind legs just follow external forces (Rosano H, Webb B, in T...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-007-0170-4

    authors: Rosano H,Webb B

    更新日期:2007-09-01 00:00:00

  • Amplification and latency in photoreceptors: integrated or separated phenomena?

    abstract::It is shown that the models for the transduction process in photoreceptors which treat latency and amplification as integrated phenomena ("integrated models") yield time scales for single photon signals ("quantum bumps") which distinctly conflict with the experimentally observed ones for the ventral nerve photorecepto...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00204697

    authors: Schnakenberg J

    更新日期:1989-01-01 00:00:00

  • Schema-based learning of adaptable and flexible prey- catching in anurans II. Learning after lesioning.

    abstract::The previous companion paper describes the initial (seed) schema architecture that gives rise to the observed prey-catching behavior. In this second paper in the series we describe the fundamental adaptive processes required during learning after lesioning. Following bilateral transections of the hypoglossal nerve, an...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-005-0014-z

    authors: Corbacho F,Nishikawa KC,Weerasuriya A,Liaw JS,Arbib MA

    更新日期:2005-12-01 00:00:00

  • A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions.

    abstract::Nicotinic acetylcholine receptors are transmembrane oligomeric proteins that mediate interconversions between open and closed channel states under the control of neurotransmitters. Fast in vitro chemical kinetics and in vivo electrophysiological recordings are consistent with the following multi-step scheme. Upon bind...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s004220050302

    authors: Edelstein SJ,Schaad O,Henry E,Bertrand D,Changeux JP

    更新日期:1996-11-01 00:00:00

  • Estimating position and velocity of a submerged moving object by the clawed frog Xenopus and by fish--a cybernetic approach.

    abstract::The lateral-line system is a unique facility of aquatic animals to locate predator, prey, or conspecifics. We present a detailed model of how the clawed frog Xenopus, or fish, can localize submerged moving objects in three dimensions by using their lateral-line system. In so doing we develop two models of a slightly d...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-005-0005-0

    authors: Franosch JM,Sichert AB,Suttner MD,van Hemmen JL

    更新日期:2005-10-01 00:00:00

  • Internally coupled ears: mathematical structures and mechanisms underlying ICE.

    abstract::In internally coupled ears (ICE), the displacement of one eardrum creates pressure waves that propagate through air-filled passages in the skull, causing a displacement of the opposing eardrum and vice versa. In this review, a thorough mathematical analysis of the membranes, passages, and propagating pressure waves re...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/s00422-016-0696-4

    authors: Vedurmudi AP,Young BA,van Hemmen JL

    更新日期:2016-10-01 00:00:00

  • Visual-vestibular interaction in the control of eye movement: mathematical modelling and computer simulation.

    abstract::After a brief description of the main anatomical structures subserving the oculomotor responses during combined vestibular and optokinetic stimulations, a mathematical model is presented. With respect to a previous model by Schmid et al. (1980), a more accurate definition of the roles of the neural mechanisms involved...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00319980

    authors: Buizza A,Schmid R

    更新日期:1982-01-01 00:00:00

  • Topological maps of protein sequences.

    abstract::A new method based on neural networks to cluster proteins into families is described. The network is trained with the Kohonen unsupervised learning algorithm, using matrix pattern representations of the protein sequences as inputs. The components (x, y) of these 20 x 20 matrix patterns are the normalized frequencies o...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00204658

    authors: Ferrán EA,Ferrara P

    更新日期:1991-01-01 00:00:00

  • On the description of neuronal output properties using spike train data.

    abstract::Neuronal output properties for input stimuli that evoke a deterministic response can be efficiently described by the interspike-interval function (Awiszus 1988a). It is shown in this paper that there are stimuli for which both the Hodgkin-Huxley (HH-) model of an action potential encoding membrane (Hodgkin and Huxley ...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/BF00204770

    authors: Awiszus F

    更新日期:1989-01-01 00:00:00

  • Phase reduction and phase-based optimal control for biological systems: a tutorial.

    abstract::A powerful technique for the analysis of nonlinear oscillators is the rigorous reduction to phase models, with a single variable describing the phase of the oscillation with respect to some reference state. An analog to phase reduction has recently been proposed for systems with a stable fixed point, and phase reducti...

    journal_title:Biological cybernetics

    pub_type: 杂志文章,评审

    doi:10.1007/s00422-018-0780-z

    authors: Monga B,Wilson D,Matchen T,Moehlis J

    更新日期:2019-04-01 00:00:00

  • Visual localization of briefly presented peripheral targets.

    abstract::Reported here are the results from two experiments designed to investigate Mateeff and Gourevich's (1983, 1984) claim that adult observers make large constant errors when judging the direction of briefly presented peripheral targets, with respect to a continuously visible scale. Experiment 1 involved a virtually exact...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/BF00204123

    authors: Mapp AP,Barbeito R,Bedell HE,Ono H

    更新日期:1989-01-01 00:00:00

  • Predictive feedback in human simulated pendulum balancing.

    abstract::In studies of human balance, it is common to fit stimulus-response data by tuning the time-delay and gain parameters of a simple delayed feedback model. Many interpret this fitted model, a simple delayed feedback model, as evidence that predictive processes are not required to explain existing data on standing balance...

    journal_title:Biological cybernetics

    pub_type: 杂志文章

    doi:10.1007/s00422-009-0325-6

    authors: Gawthrop P,Loram I,Lakie M

    更新日期:2009-08-01 00:00:00