Autoimmune myelofibrosis and systemic lupus erythematosus in a middle-aged male presenting only with severe anemia: a case report.

Abstract:

:Autoimmune myelofibrosis is a distinct clinicopathologic entity that occasionally occurs with autoimmune disorders such as systemic lupus erythematosus (SLE) and rheumatoid arthritis. Most cases of autoimmune myelofibrosis have been reported in female patients with a known history of SLE. We report a case of a middle-aged male patient with an unusual presentation of SLE and autoimmune myelofibrosis who presented only with severe anemia initially and was later diagnosed with SLE and autoimmune myelofibrosis. The patient's condition improved dramatically after treatment with corticosteroids.SLE and autoimmune myelofibrosis is a rare but potentially devastating condition. Anemia maybe the only presenting symptom in addition to bone marrow fibrosis and careful clinical and laboratory assessment is imperative. Corticosteroids maybe useful and spare patients from bone marrow transplantation.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Pundole X,Konoplev S,Oo TH,Lu H

doi

10.1097/MD.0000000000000741

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

e741

issue

19

eissn

0025-7974

issn

1536-5964

pii

00005792-201505030-00002

journal_volume

94

pub_type

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