Shaping a Subwavelength Needle with Ultra-long Focal Length by Focusing Azimuthally Polarized Light.

abstract：:Influenza virus evolves constantly in an unpredictable fashion, making it necessary to vaccinate people annually for effective prevention and control of influenza. In general, however, during the first wave of an influenza outbreak caused by a newly emerging virus strain, influenza morbidity and mortality have been ob...

journal_title：Scientific reports

authors： Zheng M,Qu D,Wang H,Sun Z,Liu X,Chen J,Li C,Li X,Chen Z

更新日期：2016-06-29 00:00:00

abstract：:Psoriatic skin differs distinctly from normal skin by its thickened epidermis. Most gene expression comparisons utilize full-thickness biopsies, with substantial amount of dermis. We assayed the transcriptomes of normal, lesional, and non-lesional psoriatic epidermis, sampled as split-thickness skin grafts, with 5'-en...

journal_title：Scientific reports

authors： Tervaniemi MH,Katayama S,Skoog T,Siitonen HA,Vuola J,Nuutila K,Sormunen R,Johnsson A,Linnarsson S,Suomela S,Kankuri E,Kere J,Elomaa O

更新日期：2016-03-15 00:00:00

abstract：:Numerous studies have investigated the association between eosinophilia and clinical outcome of patients with chronic obstructive pulmonary disease (COPD) but the evidence is conflicting. We conducted a pooled analysis of outcome measures comparing eosinophilic and non-eosinophilic COPD patients. We searched articles ...

journal_title：Scientific reports

authors： Ho J,He W,Chan MTV,Tse G,Liu T,Wong SH,Leung CCH,Wong WT,Tsang S,Zhang L,Chan RYP,Gin T,Leung J,Lau BWM,Wu WKK,Ngai SPC

更新日期：2017-10-18 00:00:00

abstract：:The cation diffusion facilitator (CDF) is a conserved family of divalent d-block metal cation transporters that extrude these cations selectively from the cytoplasm. CDF proteins are composed of two domains: the transmembrane domain, through which the cations are transported, and a regulatory cytoplasmic C-terminal do...

journal_title：Scientific reports

authors： Barber-Zucker S,Shahar A,Kolusheva S,Zarivach R

更新日期：2020-08-20 00:00:00

abstract：:Dysfunction of energy metabolism is involved in inflammatory bowel disease (IBD). This study was designed to investigate the potential of astragaloside IV (ASIV), an active ingredient of Radix Astragalus, to ameliorate colonic mucosal injury, with focusing on the implication of energy restoration in the underlying mec...

journal_title：Scientific reports

authors： Jiang XG,Sun K,Liu YY,Yan L,Wang MX,Fan JY,Mu HN,Li C,Chen YY,Wang CS,Han JY

更新日期：2017-02-02 00:00:00

abstract：:Many chemical reactions in biological cells occur at very low concentrations of constituent molecules. Thus, transcriptional gene-regulation is often controlled by poorly expressed transcription-factors, such as E.coli lac repressor with few tens of copies. Here we study the effects of inherent concentration fluctuati...

journal_title：Scientific reports

authors： Pulkkinen O,Metzler R

更新日期：2015-12-04 00:00:00

abstract：:Terrestrial microbial ecosystems are exposed to many types of disturbances varying in their spatial and temporal characteristics. The ability to cope with these disturbances is crucial for maintaining microbial ecosystem functions, especially if disturbances recur regularly. Thus, understanding microbial ecosystem dyn...

journal_title：Scientific reports

authors： König S,Worrich A,Banitz T,Centler F,Harms H,Kästner M,Miltner A,Wick LY,Thullner M,Frank K

更新日期：2018-06-22 00:00:00

abstract：:p-Alkoxyphenols (AOPs) are a class of ethers that are widely used in industrial and agricultural productions and daily necessities. p-Phenoxyphenol (PhOP) and p-pentyloxyphenol (PeOP) belong to this class and have been reported to be estrogenic in vitro. However, their in vivo estrogenic activities have rarely been of...

journal_title：Scientific reports

authors： Wang Y,Xiao H,Yang L,Jia X,Guo X,Zhang Z

更新日期：2020-10-14 00:00:00

abstract：:Baiyacha (BYC) is a kind of wild tea plant growing and utilizing in the remote mountain area of Fujian province, Southeastern China. However, scientific studies on this plant remain limited. Our results showed that BYC exhibits the typical morphological characteristics of Camellia gymnogyna Chang, a closely related sp...

journal_title：Scientific reports

authors： Jin JQ,Jiang CK,Yao MZ,Chen L

更新日期：2020-06-16 00:00:00

abstract：:Working with a large temporal dataset spanning several decades often represents a challenging task, especially when the record is heterogeneous and incomplete. The use of statistical laws could potentially overcome these problems. Here we apply Benford's Law (also called the "First-Digit Law") to the traveled distance...

journal_title：Scientific reports

authors： Joannes-Boyau R,Bodin T,Scheffers A,Sambridge M,May SM

更新日期：2015-07-09 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep30212. ...

journal_title：Scientific reports

authors： Xu H,Chen X,Xu X,Shi R,Suo S,Cheng K,Zheng Z,Wang M,Wang L,Zhao Y,Tian B,Hua Y

更新日期：2017-05-26 00:00:00

abstract：:Water is an important constituent in an abundant number of chemical systems; however, its presence complicates the analysis of in situ 1H MAS NMR investigations due to water's ease of solidification and vaporization, the large changes in mobility, affinity for hydrogen bonding interactions, etc., that are reflected by...

journal_title：Scientific reports

authors： Jaegers NR,Wang Y,Hu JZ

更新日期：2020-04-08 00:00:00

abstract：:We present a detailed experimental and theoretical study of the acoustic phonon modes in rolled-up multilayers with thickness of the layers in the nanometre and diameters in the micrometre range. We compare our results to planar, unrolled multilayers grown by molecular beam epitaxy. For the planar multilayers the expe...

journal_title：Scientific reports

authors： Brick D,Engemaier V,Guo Y,Grossmann M,Li G,Grimm D,Schmidt OG,Schubert M,Gusev VE,Hettich M,Dekorsy T

更新日期：2017-07-14 00:00:00

abstract：:Arrestins desensitize G protein-coupled receptors (GPCRs) and act as mediators of signalling. Here we investigated the interactions of arrestin-1 with two functionally distinct forms of the dim-light photoreceptor rhodopsin. Using unbiased scanning mutagenesis we probed the individual contribution of each arrestin res...

journal_title：Scientific reports

authors： Peterhans C,Lally CC,Ostermaier MK,Sommer ME,Standfuss J

更新日期：2016-06-28 00:00:00

abstract：:It is rigorously proved that ideal memcapacitors and meminductors are not passive or cyclo-passive devices. Equivalently, this implies that there exist excitation profiles that allow to extract more energy from the device than it is supplied with; so that their energy conversion efficiency exceeds 100%. This means tha...

journal_title：Scientific reports

authors： Jeltsema D,van der Schaft A

更新日期：2020-10-07 00:00:00

abstract：:Metal pollution in drinking water source has been under scrutiny as it seriously affects human health. This work examined 12 dissolved metals in the surface and overlying water of the Xiangjiang River, an important drinking water source in southern China, and characterized their distribution, identified their possible...

journal_title：Scientific reports

authors： Huang Z,Zheng S,Liu Y,Zhao X,Qiao X,Liu C,Zheng B,Yin D

更新日期：2021-01-08 00:00:00

abstract：:Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...

journal_title：Scientific reports

authors： Koide M,Yamashita T,Murakami K,Uehara S,Nakamura K,Nakamura M,Matsushita M,Ara T,Yasuda H,Penninger JM,Takahashi N,Udagawa N,Kobayashi Y

更新日期：2020-08-13 00:00:00

abstract：:Human parainfluenza type-3 virus (hPIV-3) is one of the principal aetiological agents of acute respiratory illness in infants worldwide and also shows high disease severity in the elderly and immunocompromised, but neither therapies nor vaccines are available to treat or prevent infection, respectively. Using a multid...

journal_title：Scientific reports

authors： Bailly B,Dirr L,El-Deeb IM,Altmeyer R,Guillon P,von Itzstein M

更新日期：2016-04-07 00:00:00

abstract：:Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations because of pain, the characteristics of pain and effects on activities of daily living (ADL) have not been preci...

journal_title：Scientific reports

authors： Hirai T,Yoshii T,Ushio S,Mori K,Maki S,Katsumi K,Nagoshi N,Takeuchi K,Furuya T,Watanabe K,Nishida N,Watanabe K,Kaito T,Kato S,Nagashima K,Koda M,Ito K,Imagama S,Matsuoka Y,Wada K,Kimura A,Ohba T,Katoh H,Mats

更新日期：2020-03-26 00:00:00

abstract：:We propose a novel scheme to realize an optical waveguide induced by an active Raman gain (ARG) process in a four-level N-type atomic system. Because of the nature of the ARG, there are two distinct features related to the waveguide: i) It is not absorptive, on the contrary, weak gain is presented; ii) It can be impro...

journal_title：Scientific reports

authors： Cui N,Gan Z,Zhang L

更新日期：2017-10-27 00:00:00

abstract：:The sensitivity of many ion channels to phosphatidylinositol-4,5-bisphosphate (PIP2) levels in the cell membrane suggests that PIP2 fluctuations are important and general signals modulating neuronal excitability. Yet the PIP2 dynamics of central neurons in their native environment remained largely unexplored. Here, we...

journal_title：Scientific reports

authors： Hackelberg S,Oliver D

更新日期：2018-08-28 00:00:00

abstract：:In this study we describe a new methodology to physically probe individual complexes formed between proteins and DNA. By combining nanoscale, high speed physical force measurement with sensitive fluorescence imaging we investigate the complex formed between the prokaryotic DNA repair protein UvrA2 and DNA. This approa...

journal_title：Scientific reports

authors： Simons M,Pollard MR,Hughes CD,Ward AD,Van Houten B,Towrie M,Botchway SW,Parker AW,Kad NM

更新日期：2015-12-22 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Zhu B,Liu W,Liu Y,Zhao X,Zhang H,Luo Z,Jin Y

更新日期：2020-05-27 00:00:00

abstract：:Atherosclerosis is a chronic inflammatory disease characterized by the infiltration of pro-inflammatory macrophages into a lipid-laden plaque. ITCH is an E3 ubiquitin ligase that has been shown to polarize macrophages to an anti-inflammatory phenotype. We therefore investigated the effect of ITCH deficiency on the dev...

journal_title：Scientific reports

authors： Stöhr R,Mavilio M,Marino A,Casagrande V,Kappel B,Möllmann J,Menghini R,Melino G,Federici M

更新日期：2015-03-17 00:00:00

abstract：:Taste receptors on enteroendocrine cells sense nutrients and transmit signals that control gut hormone release. This study aimed to investigate the amino acid (AA) sensing mechanisms of the ghrelin cell in a gastric ghrelinoma cell line, tissue segments and mice. Peptone and specific classes of amino acids stimulate g...

journal_title：Scientific reports

authors： Vancleef L,Van Den Broeck T,Thijs T,Steensels S,Briand L,Tack J,Depoortere I

更新日期：2015-10-29 00:00:00

abstract：:Microscopic swimming devices hold promise for radically new applications in lab-on-a-chip and microfluidic technology, diagnostics and drug delivery etc. In this paper, we demonstrate the experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and controlled solely by an oscilla...

journal_title：Scientific reports

authors： Hamilton JK,Petrov PG,Winlove CP,Gilbert AD,Bryan MT,Ogrin FY

更新日期：2017-03-09 00:00:00

abstract：:Mutations in fused in sarcoma (FUS), a DNA/RNA binding protein, are associated with familial amyotrophic lateral sclerosis (ALS). However, little is known about how ALS-causing mutations alter protein-protein and protein-RNA complexes and contribute to neurodegeneration. In this study, we identified protein arginine m...

journal_title：Scientific reports

authors： Jun MH,Ryu HH,Jun YW,Liu T,Li Y,Lim CS,Lee YS,Kaang BK,Jang DJ,Lee JA

更新日期：2017-01-17 00:00:00

abstract：:Diarrhea is a leading cause of death among young mammals, especially during weaning. Here, we investigated the effects of Cathelicidin-WA (CWA) on diarrhea, intestinal morphology, inflammatory responses, epithelial barrier and microbiota in the intestine of young mammals during weaning. Piglets with clinical diarrhea ...

journal_title：Scientific reports

authors： Yi H,Zhang L,Gan Z,Xiong H,Yu C,Du H,Wang Y

更新日期：2016-05-16 00:00:00

abstract：:Canine distemper virus (CDV) is the cause of a multisystem disease in domestic dogs and wild animals, infecting more than 20 carnivore and non-carnivore families and even infecting human cell lines in in vitro conditions. Phylogenetic classification based on the hemagglutinin gene shows 17 lineages with a phylogeograp...

journal_title：Scientific reports

authors： Duque-Valencia J,Forero-Muñoz NR,Díaz FJ,Martins E,Barato P,Ruiz-Saenz J

更新日期：2019-10-31 00:00:00