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Good reproducibility of heart rate variability after orthostatic challenge in patients with a history of acute coronary syndrome.

Abstract：

BACKGROUND:Several parameters of heart rate variability (HRV) have been shown to predict the risk of sudden cardiac death (SCD) in cardiac patients. There is consensus that risk prediction is increased when measuring HRV during specific provocations such as orthostatic challenge. For the first time, we provide data on reproducibility of such a test in patients with a history of acute coronary syndrome. METHODS:Sixty male patients (65 ± 8 years) with a history of acute coronary syndrome on stable medication were included. HRV was measured in supine (5 min) and standing (5 min) position on 2 occasions separated by two weeks. For risk assessment relevant time-domain [standard deviation of all R-R intervals (SDNN) and root mean squared standard differences between adjacent R-R intervals (RMSSD)], frequency domain [low-frequency power (LF), high-frequency power (HF) and LF/HF power ratio] and short-term fractal scaling component (DF1) were computed. Absolute reproducibility was assessed with the standard errors of the mean (SEM) and 95% limits of random variation, and relative reproducibility by the intraclass correlation coefficient (ICC). RESULTS:We found comparable SEMs and ICCs in supine position and after an orthostatic challenge test. All ICCs were good to excellent (ICCs between 0.636 and 0.869). CONCLUSIONS:Reproducibility of HRV parameters during orthostatic challenge is good and comparable with supine position.

journal_name

J Electrocardiol

journal_title

Journal of electrocardiology

authors

Schäfer D,Nil M,Herzig D,Eser P,Saner H,Wilhelm M

doi

10.1016/j.jelectrocard.2015.04.004

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

696-702

issue

4

eissn

0022-0736

issn

1532-8430

pii

S0022-0736(15)00111-9

journal_volume

48

pub_type

杂志文章

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