Abstract:
AIM:Low survival rate was previously described after cardiac arrest in cancer patients and may challenge the appropriateness of intensive care unit (ICU) admission after return of spontaneous circulation (ROSC). Objectives of this study were to report outcome and characteristics of cancer patients admitted to the ICU after cardiac arrest. METHODS:A retrospective chart review in seven medical ICUs in France, in 2002-2012. We studied consecutive patients with malignancies admitted after out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA). RESULTS:Of 133 included patients of whom 61% had solid tumors, 48 (36%) experienced OHCA and 85 (64%) IHCA. Cardiac arrest was related to the malignancy or its treatment in 47% of patients. Therapeutic hypothermia was used in 51 (41%) patients. The ICU mortality rate was 98/133 (74%). Main causes of ICU death were refractory shock or multiple organ failure (n = 64, 48%) and neurological injury (n = 27, 20%); 42 (32%) patients died in ICU after treatment-limitation decisions. Twenty-four (18%) patients were discharged alive from the hospital. Overall 6-month survival rate was 14% (18/133, 95% confidence interval, 8-21%). Survival rates at ICU discharge and after 6 months did not differ significantly across type of malignancy or between the OHCA and IHCA groups, and neither were they significantly different from those in matched controls who had cardiac arrest but no malignancy. CONCLUSIONS:Even if low, the 6-month survival rate of 14% observed in cancer patients admitted to the ICU after cardiac arrest and ROSC may support the admission of these patients to the ICU and may warrant an initial full-code ICU management.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Champigneulle B,Merceron S,Lemiale V,Geri G,Mokart D,Bruneel F,Vincent F,Perez P,Mayaux J,Cariou A,Azoulay Edoi
10.1016/j.resuscitation.2015.04.011subject
Has Abstractpub_date
2015-07-01 00:00:00pages
38-44eissn
0300-9572issn
1873-1570pii
S0300-9572(15)00164-1journal_volume
92pub_type
杂志文章,多中心研究相关文献
RESUSCITATION文献大全abstract:BACKGROUND:The association between the interval between collapse and defibrillation and outcome is well described in out of hospital cardiac arrest but not as well in in-hospital cardiac arrest. We report the outcome among patients who suffered an in-hospital cardiac arrest and were found in ventricular fibrillation (V...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.03.018
更新日期:2005-08-01 00:00:00
abstract::Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation acute myocardial infarction (STEMI). In comatose survivors of cardiac arrest, mild induced hypothermia (MIH) improves neurological recovery. In the present study, we investigated feasibility and safety of combining ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2007.01.016
更新日期:2007-08-01 00:00:00
abstract:AIM:We sought to examine whether the outcomes of out-of-hospital cardiopulmonary arrest (OHCA) patients differed between weekday and weekend/holiday admissions, or between daytime and nighttime admissions. METHODS:From a national registry of OHCA events in Japan between 2005 and 2008, 173,137 cases where the call-to-h...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2011.02.007
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:For prolonged VF, perfusion of the myocardium by pre-shock chest compressions can improve myocardial readiness for successful defibrillation. Characteristics of the VF waveform correlate with the duration of VF when there is no structural heart disease. A "smart" automated external defibrillator (AED) could ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2005.10.017
更新日期:2006-06-01 00:00:00
abstract:AIM:Each minute is crucial in the treatment of out-of-hospital cardiac arrest (CA). Immediate chest compressions and early defibrillation are keys to good outcomes. We hypothesized that a coordinated effort of alerting trained local neighborhood volunteers (vols) simultaneously with 911 activation of professional EMS p...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.09.016
更新日期:2019-11-01 00:00:00
abstract:AIM:Comparing the outcome after out-of-hospital cardiac arrest (OHCA) in men and women and to determine whether sex modifies the effect of targeted temperature management (TTM) at 33 or 36°C. METHODS:The TTM trial randomized 950 patients to TTM at 33 or 36°C for 24h. This predefined sub-study of the TTM trial assessed...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.resuscitation.2015.06.030
更新日期:2015-11-01 00:00:00
abstract:AIMS:The cerebellum is among the brain regions most vulnerable to damage caused by cardiac arrest, and cerebellar Purkinje cell loss may contribute to neurologic dysfunction, including post-hypoxic myoclonus. However, it remains unknown whether cerebellar Purkinje cells are protected by post-cardiac arrest therapeutic ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2012.05.022
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Despite a promising association between VF waveform characteristics and prognosis after resuscitation, studies with VF-guided treatment have so far not improved outcomes. While driven by the idea that the VF waveform reflects arrest duration, increasing evidence suggests that pre-existent disease-related cha...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.03.029
更新日期:2017-06-01 00:00:00
abstract::Most survival outcomes in out-of-hospital cardiac arrest (OHCA) are provided by emergency medical services (EMS) without a doctor on board. Our objective was to determine such outcomes in a whole country with public physician-led EMS. METHODS:We analyzed data from a nationwide prospective registry of OHCA cases atten...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2017.01.029
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To assess the impact of a formal, structured resuscitation team in the emergency department (ED) on the success rate of cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) patients. METHODS:This is a "three-phase" (organized, transitional, and re-organized), prospective study in whi...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2003.09.007
更新日期:2004-02-01 00:00:00
abstract:AIM:The American Heart Association (AHA) and the Institute of Medicine have published a national "call-to-action" to improve survival from in-hospital cardiopulmonary arrest (IHCA). Our aim was to determine if more-active hospital participation in standardized in-situ mock code (ISMC) training is associated with increa...
journal_title:Resuscitation
pub_type: 杂志文章,多中心研究
doi:10.1016/j.resuscitation.2018.09.020
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Continuous cardiac index (CCI) monitoring can provide information to assist in hemodynamic support. However, pulmonary artery catheters (PAC) pose logistic challenges in acute care settings. We hypothesized that CCI measured with a calibrated minimally invasive technique (LiDCO/PulseCO, UK) would have good...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2009.04.015
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Chest compressions before initial defibrillation attempts have been shown to increase successful defibrillation. This animal study was designed to assess whether ventricular fibrillation mean frequency after 90 s of basic life support cardiopulmonary resuscitation (CPR) may be used as an indica...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(01)00388-4
更新日期:2001-11-01 00:00:00
abstract:INTRODUCTION:Reports about the efficacy of precordial thump (PT) in the termination of ventricular arrhythmias (VA) vary widely. Very little recent data about the mechanical termination of VA induced during programmed ventricular stimulation are available. METHODS:We prospectively studied 485 consecutive patients (May...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2008.07.022
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:During normovolaemic haemodilution arterial O(2)-content decreases exponentially. Nevertheless, tissue oxygenation is first maintained initially by increased organ perfusion and O(2)-extraction. As soon as these compensatory mechanisms are exhausted, myocardial ischaemia and tissue hypoxia occur at an individ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(02)00408-2
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:We evaluated the association between nifekalant or amiodarone on hospital admission and in-hospital mortality for cardiac arrest patients with persistent ventricular fibrillation on hospital arrival. METHODS:This was a retrospective cohort study using the Japanese Diagnosis Procedure Combination inpatient d...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.08.017
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To study the changes of brain water diffusion and cerebral haemodynamics of cortical areas using magnetic resonance imaging (MRI) in canine models of cardiac arrest (CA) and restoration of spontaneous circulation (ROSC). The secondary study objective was to evaluate whether MRI can be used to observe haemodyn...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2011.10.017
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Out-of-hospital cardiac arrest (OHCA) initiates a chain of responses including emergency medical service mobilization and medical treatment, transfer and admission first to a hospital Emergency Department (ED) and then usually to an intensive care unit and ward. Costly pre- and in-hospital care may be follow...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.10.024
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Mathematical optimisation models have recently been applied to identify ideal Automatic External Defibrillator (AED) locations that maximise coverage of Out of Hospital Cardiac Arrest (OHCA). However, these fixed location models cannot relocate existing AEDs in a flexible way, and have nearly exclusively bee...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2018.01.055
更新日期:2018-04-01 00:00:00
abstract:AIM:To assess the experience, knowledge and attitudes of local primary health-care doctors towards resuscitation in out-of-hospital cardiac arrest. METHODS:We conducted a survey of general practitioners (GPs) working in both private and public sectors. The survey consisted of 29 questions and was self-administered. R...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2004.11.021
更新日期:2005-05-01 00:00:00
abstract::The quality of education, CPR guidelines and the chain of survival all contribute to patient outcome following cardiac arrest. Increasing concerns about patient safety have focused attention on the methods used to train and prepare doctors for clinical practice. Reductions in clinical exposure at both undergraduate an...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/j.resuscitation.2007.01.005
更新日期:2007-05-01 00:00:00
abstract::A 52-year-old previously healthy man experienced acute severe dyspnoea after suffering from gastroenteritis for 3 days. After arrival of the ambulance, cardiac arrest with an initial rhythm of electro mechanical dissociation occurred. Circulation was restored after 10 min of cardiopulmonary resuscitation but soon card...
journal_title:Resuscitation
pub_type: 杂志文章,评审
doi:10.1016/s0300-9572(98)00066-5
更新日期:1998-07-01 00:00:00
abstract::Sudden cardiac arrest remains an important health care problem. If survival rates of all regions would equal those of the best performers, literally thousands of lives would be saved. Similar to injury, there is a need for an epidemiology-based approach for planning and execution of countermeasures. In this policy pap...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2014.01.032
更新日期:2014-05-01 00:00:00
abstract:AIM:Approximately 5% of newborns receive positive pressure ventilation (PPV) for successful transition. Guidelines urge providers to ensure effective PPV for 30-60s before considering chest compressions and intravenous therapy. Pauses in this initial PPV may delay recovery of spontaneous respiration. The aim was to fin...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2016.07.231
更新日期:2016-10-01 00:00:00
abstract::Recent reports suggest that endorphins may contribute to hemodynamic depression in septic and hemorrhagic shock. There is also evidence that reversal of endorphin effects with high dose naloxone may improve hemodynamic function and improve survival in shock states. The purpose of this study was to examine the effects ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/0300-9572(86)90076-6
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to determine the causes and the prognosis of consecutive patients resuscitated from cardiac arrest occurring in a general hospital. We assessed 28 females and 94 males (aged 13-82 years) who were resuscitated from cardiac arrest not attributable to acute myocardial infarction. V...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(03)00154-0
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Measuring survival from sudden out-of-hospital cardiac arrest (OOH-CA) is often used as a benchmark of the quality of a community's emergency medical service (EMS) system. The definition of OOH-CA survival rates depends both upon the numerator (surviving cases) and the denominator (all cases). PURPOSE:The p...
journal_title:Resuscitation
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.resuscitation.2004.02.007
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:During cardiac arrest and after successful resuscitation a continuum of ischaemia-reperfusion injury develops. Mild hypothermia exerts protective effects in the postresuscitation phase but also alters CO₂ production and solubility, which may lead to deleterious effects if overlooked when adjusting the ventil...
journal_title:Resuscitation
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.resuscitation.2011.04.022
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:We studied how effectively a mixed group of helpers could ventilate a manikin with a new rescue breathing device after a short period of instruction. The device consists of a mouthcap, a "glossopalatinal tube" (GPT) reaching between tongue and palate and a connector for a bag, ventilator or the rescuers mo...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/s0300-9572(03)00205-3
更新日期:2003-11-01 00:00:00
abstract:AIM:The aim of this study was to describe patient characteristics, event characteristics, and outcomes for patients with in-hospital cardiac arrest in Denmark. METHODS:Data was obtained from DANARREST. DANARREST is a nationwide registry that covers all in-hospital cardiac arrests in Denmark with a clinical indication ...
journal_title:Resuscitation
pub_type: 杂志文章
doi:10.1016/j.resuscitation.2019.04.046
更新日期:2019-07-01 00:00:00