Abstract：
BACKGROUND:Linguistic, cultural and genetic characteristics of the Malagasy suggest that both Africans and Island Southeast Asians were involved in the colonization of Madagascar. Populations from the Indonesian archipelago played an especially important role because linguistic evidence suggests that the Malagasy language branches from the Southeast Barito language family of southern Borneo, Indonesia, with the closest language spoken today by the Ma'anyan. To test for a genetic link between Malagasy and these linguistically related Indonesian populations, we studied the Ma'anyan and other Indonesian ethnic groups (including the sea nomad Bajo) that, from their historical and linguistic contexts, may be modern descendants of the populations that helped enact the settlement of Madagascar. RESULT:A combination of phylogeographic analysis of genetic distances, haplotype comparisons and inference of parental populations by linear optimization, using both maternal and paternal DNA lineages, suggests that Malagasy derive from multiple regional sources in Indonesia, with a focus on eastern Borneo, southern Sulawesi and the Lesser Sunda islands. CONCLUSION:Settlement may have been mediated by ancient sea nomad movements because the linguistically closest population, Ma'anyan, has only subtle genetic connections to Malagasy, whereas genetic links with other sea nomads are more strongly supported. Our data hint at a more complex scenario for the Indonesian settlement of Madagascar than has previously been recognized.
journal_name
BMC Genomicsjournal_title
BMC genomicsauthors
Kusuma P,Cox MP,Pierron D,Razafindrazaka H,Brucato N,Tonasso L,Suryadi HL,Letellier T,Sudoyo H,Ricaut FXdoi
10.1186/s12864-015-1394-7subject
Has Abstractpub_date
2015-03-17 00:00:00pages
191issn
1471-2164pii
10.1186/s12864-015-1394-7journal_volume
16pub_type
杂志文章相关文献
BMC GENOMICS文献大全abstract：BACKGROUND:Understanding the genetic basis of adaptive evolution is one of the major goals in evolutionary biology. Recently, it has been revealed that gene copy number variations (GCNVs) constitute significant proportions of genomic diversities within natural populations. However, it has been unclear whether GCNVs are...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-15-735
更新日期：2014-08-29 00:00:00
abstract：BACKGROUND:Fungal plant pathogens belonging to the genus Venturia cause damaging scab diseases of members of the Rosaceae. In terms of economic impact, the most important of these are V. inaequalis, which infects apple, and V. pirina, which is a pathogen of European pear. Given that Venturia fungi colonise the sub-cuti...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-017-3699-1
更新日期：2017-05-02 00:00:00
abstract：BACKGROUND:Bacteroides thetaiotaomicron, a predominant member of the human gut microbiota, is characterized by its ability to utilize a wide variety of polysaccharides using the extensive saccharolytic machinery that is controlled by an expanded repertoire of transcription factors (TFs). The availability of genomic seq...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-14-873
更新日期：2013-12-12 00:00:00
abstract：BACKGROUND:Matrix attachment regions (MAR) are the sites on genomic DNA that interact with the nuclear matrix. There is increasing evidence for the involvement of MAR in regulation of gene expression. The unsuitability of experimental detection of MAR for genome-wide analyses has led to the development of computational...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-8-418
更新日期：2007-11-15 00:00:00
abstract：BACKGROUND:Williams syndrome transcription factor (WSTF) is a multifaceted protein that is involved in several nuclear processes, including replication, transcription, and the DNA damage response. WSTF participates in a chromatin-remodeling complex with the ISWI ATPase, SNF2H, and is thought to contribute to the mainte...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-14-740
更新日期：2013-10-29 00:00:00
abstract：BACKGROUND:Atlantic salmon have been subject to domestication for approximately ten generations, beginning in the early 1970s. This process of artificial selection will have created various genetic differences between wild and farmed stocks. Each year, hundreds of thousands of farmed fish escape into the wild. These es...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-15-884
更新日期：2014-10-09 00:00:00
abstract：BACKGROUND:Sugarcane is a major sugar and biofuel crop, but genomic research and molecular breeding have lagged behind other major crops due to the complexity of auto-allopolyploid genomes. Sugarcane cultivars are frequently aneuploid with chromosome number ranging from 100 to 130, consisting of 70-80 % S. officinarum,...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-016-2817-9
更新日期：2016-06-10 00:00:00
abstract：BACKGROUND:The bulldog calf syndrome is a lethal form of the inherited congenital chondrodysplasias. Among the progeny of the polled Holstein bull Energy P cases of lethal chondrodysplasia were observed. Pedigrees of the cases and the frequency of 3/8 cases among the offspring of Energy P at our teaching and experiment...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-017-4153-0
更新日期：2017-10-10 00:00:00
abstract：BACKGROUND:Pekin duck products have become popular in Asia over recent decades and account for an increasing market share. However, the genetic mechanisms affecting carcass growth in Pekin ducks remain unknown. This study aimed to identify quantitative trait loci affecting body size and carcass yields in Pekin ducks. ...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-018-5379-1
更新日期：2019-01-03 00:00:00
abstract：BACKGROUND:S. aureus is one of the main pathogens responsible for the intra-mammary infection in dairy ruminants. Although much work has been carried out to understand the complex physiological and cellular events that occur in the mammary gland in response to S. aureus, the protective mechanisms are still poorly under...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-13-540
更新日期：2012-10-09 00:00:00
abstract：BACKGROUND:Crustacean moulting is a complex process involving many regulatory pathways. A holistic approach to examine differential gene expression profiles of transcripts relevant to the moulting process, across all moult cycle stages, was used in this study. Custom cDNA microarrays were constructed for Portunus pelag...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-12-147
更新日期：2011-03-12 00:00:00
abstract：BACKGROUND:High throughput experiments resulted in many genomic datasets and hundreds of candidate disease genes. To discover the real disease genes from a set of candidate genes, computational methods have been proposed and worked on various types of genomic data sources. As a single source of genomic data is prone of...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-13-S7-S27
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Sclerotinia Stem Rot (SSR), caused by the fungal pathogen Sclerotinia sclerotiorum, is ubiquitous in cooler climates where soybean crops are grown. Breeding for resistance to SSR remains challenging in crops like soybean, where no single gene provides strong resistance, but instead, multiple genes work toget...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-017-4160-1
更新日期：2017-11-07 00:00:00
abstract：BACKGROUND:Soybean (Glycine max (L. Merr.)) resistance to any population of Heterodera glycines (I.), or Fusarium virguliforme (Akoi, O'Donnell, Homma & Lattanzi) required a functional allele at Rhg1/Rfs2. H. glycines, the soybean cyst nematode (SCN) was an ancient, endemic, pest of soybean whereas F. virguliforme caus...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-13-368
更新日期：2012-08-02 00:00:00
abstract：BACKGROUND:Improving fiber quality is a major challenge in cotton breeding, since the molecular basis of fiber quality traits is poorly understood. Fine mapping and candidate gene prediction of quantitative trait loci (QTL) controlling cotton fiber quality traits can help to elucidate the molecular basis of fiber quali...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-016-2605-6
更新日期：2016-04-19 00:00:00
abstract：BACKGROUND:The problem of supervised DNA sequence classification arises in several fields of computational molecular biology. Although this problem has been extensively studied, it is still computationally challenging due to size of the datasets that modern sequencing technologies can produce. RESULTS:We introduce CLA...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-015-1419-2
更新日期：2015-03-25 00:00:00
abstract：BACKGROUND:Transcription factors (TFs) play essential roles during plant development and response to environmental stresses. However, the relationships among transcription factors, cis-acting elements and target gene expression under endo- and exogenous stimuli have not been systematically characterized. RESULTS:Here,...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-018-4469-4
更新日期：2018-05-09 00:00:00
abstract：BACKGROUND:Major changes in gene expression occur in the fetal brain to modulate the function of this organ postnatally. Thus, factors can alter the genomics of the fetal brain, predisposing to neurological disorders later in life. We hypothesized that the physiological dynamics of the immune system transcriptome of th...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-15-1001
更新日期：2014-11-19 00:00:00
abstract：BACKGROUND:Lateral gene transfer (LGT) is an important evolutionary process in microbial evolution. In sewage treatment plants, LGT of antibiotic resistance and xenobiotic degradation-related proteins has been suggested, but the role of LGT outside these processes is unknown. Microbial communities involved in Enhanced ...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-015-1752-5
更新日期：2015-07-16 00:00:00
abstract：BACKGROUND:Reliable indicators for the onset of flowering are not available for most perennial monocarpic species, representing a drawback for crops such as bamboo, agave and banana. The ability to predict and control the transition to the reproductive stage in A. tequilana would represent an advantage for field manage...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-019-5808-9
更新日期：2019-06-10 00:00:00
abstract：BACKGROUND:Litchi (Litchi chinensis Sonn.) is an economically important evergreen fruit tree widely cultivated in subtropical areas. Low temperature is absolutely required for floral induction of litchi, but its molecular mechanism is not fully understood. Leaves of litchi played a key role during floral induction and ...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-017-3747-x
更新日期：2017-05-10 00:00:00
abstract：BACKGROUND:High-throughput sequencing has opened up exciting possibilities in population and conservation genetics by enabling the assessment of genetic variation at genome-wide scales. One approach to reduce genome complexity, i.e. investigating only parts of the genome, is reduced-representation library (RRL) sequenc...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-15-16
更新日期：2014-01-10 00:00:00
abstract：BACKGROUND:We have previously reported on paucity of mitochondrial DNA (mtDNA) haplogroups J and K among Finnish endurance athletes. Here we aimed to further explore differences in mtDNA variants between elite endurance and sprint athletes. For this purpose, we determined the rate of functional variants and the mutatio...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-019-6171-6
更新日期：2019-10-29 00:00:00
abstract：BACKGROUND:The AP2/ERF transcription factor, one of the largest gene families in plants, plays a crucial role in the regulation of growth and development, metabolism, and responses to biotic and abiotic stresses. Castor bean (Ricinus communis L., Euphobiaceae) is one of most important non-edible oilseed crops and its s...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-14-785
更新日期：2013-11-13 00:00:00
abstract：BACKGROUND:Gaucher disease is caused by defective glucocerebrosidase activity and the consequent accumulation of glucosylceramide. The pathogenic pathways resulting from lipid laden macrophages (Gaucher cells) in visceral organs and their abnormal functions are obscure. RESULTS:To elucidate this pathogenic pathway, de...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-12-20
更新日期：2011-01-11 00:00:00
abstract：BACKGROUND:Evolutionary theory indicates that the dynamics of aging in the soma and reproductive tissues may be distinct. This difference arises from the fact that only the germline lineage establishes future generations. In the soma, changes in the landscape of heterochromatin have been proposed to have an important r...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-019-5668-3
更新日期：2019-04-23 00:00:00
abstract：BACKGROUND:Animals are thought to achieve lignocellulose digestion via symbiotic associations with gut microbes; this view leads to significant focus on bacteria and fungi for lignocellulolytic systems. The presence of biomass conversion systems hardwired into animal genomes has not yet been unequivocally demonstrated....
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-018-4861-0
更新日期：2018-06-20 00:00:00
abstract：BACKGROUND:Fusarium head blight (FHB), caused mainly by Fusarium graminearum (Fg) Schwabe (teleomorph: Gibberellazeae Schwble), brings serious damage to wheat production. Chinese wheat landrace Wangshuibai is one of the most important resistance sources in the world. The knowledge of mechanism underlying its resistance...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-14-197
更新日期：2013-03-21 00:00:00
abstract：BACKGROUND:The P1B-ATPase subfamily is an important group involved in transporting heavy metals and has been extensively studied in model plants, such as Arabidopsis thaliana and Oryza sativa. Emerging evidence indicates that one homolog in Glycine max is also involved in cadmium (Cd) stress, but the gene family has no...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/s12864-016-2730-2
更新日期：2016-05-20 00:00:00
abstract：BACKGROUND:The sequence of the pathogen Mycobacterium tuberculosis (Mtb) strain H37Rv has been available for over a decade, but the biology of the pathogen remains poorly understood. Genome sequences from other Mtb strains and closely related bacteria present an opportunity to apply the power of comparative genomics to...
journal_title：BMC genomics
pub_type： 杂志文章
doi：10.1186/1471-2164-13-120
更新日期：2012-03-28 00:00:00
