Prediabetes, diagnosed and undiagnosed diabetes, their risk factors and association with knowledge of diabetes in rural Bangladesh: The Bangladesh Population-based Diabetes and Eye Study.

abstract：:Observations from clinical studies suggest that low serum levels of testosterone in men are often associated with obesity, insulin resistance, and metabolic compromise. Indeed, the clinical symptoms of late-onset hypogonadism are markedly similar to those of Type 2 diabetes mellitus (T2DM) and metabolic syndrome, and ...

journal_title：Journal of diabetes

authors： Jones TH

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:  Diabetic peripheral neuropathy (DPN) is one of the complications of type 2 diabetes mellitus (T2DM) that decreases the quality of life of T2DM patients. Very few studies have found an association between the development and progression of DPN in T2DM and angiotensin-converting enzyme (ACE) gene insertion/d...

journal_title：Journal of diabetes

authors： Mansoor Q,Javaid A,Bilal N,Ismail M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Intrahepatic expression of dipeptidyl peptidase-4 (DPP4), and circulating DPP4 (cDPP4) levels and its enzymatic activity, are increased in non-alcoholic fatty liver disease (NAFLD) and in type 2 diabetes mellitus and/or obesity. DPP4 has been implicated as a causative factor in NAFLD progression but few stud...

journal_title：Journal of diabetes

authors： Williams KH,Vieira De Ribeiro AJ,Prakoso E,Veillard AS,Shackel NA,Brooks B,Bu Y,Cavanagh E,Raleigh J,McLennan SV,McCaughan GW,Keane FM,Zekry A,Gorrell MD,Twigg SM

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a prevalent complication of diabetes, and oxidative stress is an important feature of diabetic ED. Oxidative stress-induced damage plays a pivotal role in the development of tissue alterations. However, the deleterious effects of oxidative stress in the corpus cavernosum with the...

journal_title：Journal of diabetes

authors： Castela A,Gomes P,Domingues VF,Paíga P,Costa R,Vendeira P,Costa C

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Currently, there is no consensus regarding the medical treatment of chronic Charcot neuroarthropathy (CN) of foot, except for effective off-loading. Because tarsal bones are predominantly trabecular, teriparatide may improve the macroarchitecture of foot bones in chronic CN. METHODS:People with diabetes and...

journal_title：Journal of diabetes

authors： Rastogi A,Hajela A,Prakash M,Khandelwal N,Kumar R,Bhattacharya A,Mittal BR,Bhansali A,Armstrong DG

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have supported the association among depression, obesity, and type 2 diabetes, but the causality remains controversial in Chinese adults. In this longitudinal study, we evaluated the synergistic effect of depression and obesity on the risk of type 2 diabetes. METHODS:This study inclu...

journal_title：Journal of diabetes

authors： Ning F,Zhang D,Xue B,Zhang L,Zhang J,Zhu Z,Zhang D,Gao R,Pang Z,Qiao Q,Qingdao Diabetes Prevention Program.

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Atherosclerosis may be stimulated by the increased presence of insulin and tumor necrosis-factor-α (TNFα) with subsequent expression of vascular cell adhesion molecule-1 (VCAM-1). We hypothesized that extracellular signal-regulated kinase-5 (ERK5) plays an important role in insulin and TNFα-stimulated total ...

journal_title：Journal of diabetes

authors： Mackesy DZ,Goalstone ML

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Although diabetes is associated with ethnicity and worse cardiac surgery outcomes, no research has been done to study the effect of both diabetes and ethnicity on cardiac surgery outcomes in a multiethnic Southeast Asian cohort. Hence, this study aimed to delineate the association of ethnicity on outcomes af...

journal_title：Journal of diabetes

authors： Moorthy V,Liu W,Chan SP,Chew STH,Ti LK

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is highly prevalent worldwide, and its individual components obesity, diabetes, and hypertension have been identified as risk factors to develop severe coronavirus disease 2019 (COVID-19); however, data on MetS and clinical outcomes in COVID-19 are scarce. This study aims to determi...

journal_title：Journal of diabetes

authors： Lohia P,Kapur S,Benjaram S,Pandey A,Mir T,Seyoum B

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Brown adipose tissue (BAT) has been regarded as a potential target organ to combat obesity and related metabolic disorders. However, the effect of BAT activation on the development of diabetic kidney disease (DKD) remains unclear. METHODS:Diabetic mice were induced by streptozotocin (STZ) combined with a hi...

journal_title：Journal of diabetes

authors： Cai YY,Zhang HB,Fan CX,Zeng YM,Zou SZ,Wu CY,Wang L,Fang S,Li P,Xue YM,Guan MP

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:In people with chronic kidney disease (CKD), HbA1c may be a problematic measure of glycemic control. Glycated albumin and fructosamine have been proposed as better markers of hyperglycemia in CKD. In the present study we investigated associations of HbA1c, glycated albumin, and fructosamine with fasting gluc...

journal_title：Journal of diabetes

authors： Jung M,Warren B,Grams M,Kwong YD,Shafi T,Coresh J,Rebholz CM,Selvin E

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Diabetes is a risk factor for various cancers, but its prognostic role in renal cell carcinoma (RCC) is controversial and understudied. This study investigated the prognostic value of type 2 diabetes (T2D) in RCC patients. METHODS:The clinicopathological and follow-up data of 451 RCC patients undergoing rad...

journal_title：Journal of diabetes

authors： Yang H,Yin K,Wang Y,Xia M,Zhang R,Wang W,Chen J,Wang C,Shuang W

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Obesity and shorter telomeres increase the risk for diabetes complications and mortality. However, the relationship between obesity and telomere length in diverse Asian populations with type 2 diabetes (T2D) is not well understood. This study examined the association of baseline and changes in obesity indice...

journal_title：Journal of diabetes

authors： Gurung RL,M Y,Liu S,Liu JJ,Chan SM,Moh MC,Ang K,Tang WE,Sum CF,Tavintharan S,Lim SC,SMART2D Study.

更新日期：2019-05-01 00:00:00

abstract：:Highlights A large retrospective study indicates no association between GDM and most types of cancer; this is in contrast to a few smaller studies that have suggested an association with cancer. An increased risk of thyroid cancer in mothers with GDM was demonstrated. While this risk requires further investigation, it...

journal_title：Journal of diabetes

authors： Pace R,Rahme E,Dasgupta K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...

journal_title：Journal of diabetes

authors： Chatterjee S,Chatterjee S

更新日期：2014-05-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) is the primary incretin hormone secreted from the intestine upon uptake of food to stimulate insulin secretion from pancreatic β-cells. GLP-1 exerts its effects by binding to its G-protein coupled receptors and subsequently activating adenylate cyclase, leading to generation of cyclic a...

journal_title：Journal of diabetes

authors： Ma X,Guan Y,Hua X

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:To investigate the effect of hydroxypropyl methylcellulose (HPMC) on weight loss and metabolic disorders associated with obesity using a high-fat diet-induced obese mouse model under a high-fat diet regimen. METHODS: Obese male C57BL/6J (B6) mice were fed either a high-fat (60% kcal), low-fat (10% kcal), or...

journal_title：Journal of diabetes

authors： Hung SC,Anderson WH,Albers DR,Langhorst ML,Young SA

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Liver X receptors (LXRs) including LXRα and LXRβ are members of the nuclear hormone receptor superfamily of ligand activated transcription factors, which serve as lipid sensors to regulate expression of genes controlling many aspects of cholesterol and fatty acid metabolism. The liver is the central organ in...

journal_title：Journal of diabetes

authors： Zhang X,Liu J,Su W,Wu J,Wang C,Kong X,Gustafsson JÅ,Ding J,Ma X,Guan Y

更新日期：2014-05-01 00:00:00

abstract：:This article reviews the known pathophysiological mechanisms of comorbid gastroesophageal reflux disease (GERD) in the diabetic patient, discusses therapeutic options in care, and provides an approach to its evaluation and management. We searched for review articles published in the past 10 years through a PubMed sear...

journal_title：Journal of diabetes

authors： Punjabi P,Hira A,Prasad S,Wang X,Chokhavatia S

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) analogues have emerged as insulin secretagogues and are widely used in type 2 diabetic patients. GLP-1 analogues also demonstrate a promotion of beta cell proliferation and reduction of apoptosis in rodents. In the present study, we investigated the protection of pancreatic be...

journal_title：Journal of diabetes

authors： Luo X,Pan L,Nie A,Wang Q,Gu Y,Li F,Zhang H,Li W,Li X

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Primary care physicians frequently encounter people with type 2 diabetes mellitus (T2DM) with discordant values for fasting glucose and HbA1c. The aim of this study was to identify the prevalence and characteristics of people in whom blood glucose and HbA1c did not match. METHODS:Overall, 64 553 people with...

journal_title：Journal of diabetes

authors： Rathmann W,Bongaerts B,Kostev K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The aims of the present study were to examine the association of cigarette smoking and alcohol consumption with impaired β-cell function in Chinese men, particularly the interaction of smoking and alcohol consumption on impaired insulin secretion. METHODS:A population-based cross-sectional study was perform...

journal_title：Journal of diabetes

authors： Xu M,Zhou Y,Xu B,Sun J,Wang T,Lu J,Lai S,Bi Y,Wang W,Ning G

更新日期：2016-05-01 00:00:00

abstract：:Crossover design has been widely used in late-phase clinical studies, as well as in pharmacokinetic and pharmacodynamic, bioequivalence, and medical device studies; however, its interpretability and applicability continue to be debated. Herein we provide discussions around a crossover design's scientific benefit, appl...

journal_title：Journal of diabetes

authors： Wang T,Malone J,Fu H,Heilmann C,Qu Y,Huster WJ

更新日期：2016-09-01 00:00:00

abstract：:Following on from impressive economic development and urbanization, China is currently experiencing a high prevalence of metabolic syndrome. Patients with metabolic syndrome suffer from the "The Deadly Quartet" of hyperglycemia, hypertriglyceridemia, hypertension, and central (or upper body) obesity. Current treatment...

journal_title：Journal of diabetes

authors： Xia X,Weng J

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Limited information exists regarding the efficacy of pregabalin in Chinese patients with painful diabetic peripheral neuropathy (pDPN). METHODS:An 11-week double-blind placebo-controlled trial was performed in Chinese pDPN patients randomized (1 : 1) to 300 mg/day pregabalin or placebo. The primary outcome ...

journal_title：Journal of diabetes

authors： Mu Y,Liu X,Li Q,Chen K,Liu Y,Lv X,Xu X,Fan D,Shang N,Yang R,Pauer L,Pan C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Insulin therapy should be strongly considered in newly diagnosed type 2 diabetic (T2D) patients with severe hyperglycemia. However, whether insulin be continued or patients switched to an oral antidiabetic drug (OAD) after short-term intensive insulin therapy (ITT) is not clear. METHODS:After ITT for 10-14 ...

journal_title：Journal of diabetes

authors： Cheng Q,Yang S,Zhao C,Wang Z,Feng Z,Li R,Ye P,Zhang S,Deng H,Zhou B,Long J,Gong L,Qing H,Luo C,Li Q

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Women with previous gestational diabetes mellitus (pGDM) are at increased risk of developing type 2 diabetes later in life. The aim of this study was to determine if circulating levels of metabolic hormones 12 weeks following a GDM pregnancy are associated with an increased risk of type 2 diabetes 8-10 years...

journal_title：Journal of diabetes

authors： Lappas M,Jinks D,Ugoni A,Louizos CC,Permezel M,Georgiou HM

更新日期：2015-07-01 00:00:00

abstract：:Skin autofluorescence is increased in diabetes, rises with age, and predicts diabetes-related complications. Exposure to secondhand smoke, because one or more family members are smokers, further increases skin autofluorescence in children and young adults with type 1 diabetes. Elimination of passive smoking should be ...

journal_title：Journal of diabetes

authors： Vollenbrock CE,Van Waateringe RP,Veeze HJ,Aanstoot HJ,Wolffenbuttel BH

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...

journal_title：Journal of diabetes

authors： Patel V,Joharapurkar A,Gandhi T,Patel K,Dhanesha N,Kshirsagar S,Dhote V,Detroja J,Bahekar R,Jain M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:With the current obesity epidemic, the search for effective weight loss approaches is required. In the present study, changes in weight, body composition and cardiovascular (CV) risk in response to a low-fat, reduced-energy diet (LFRE), a low-carbohydrate/high-protein diet (LCHP), or a commercially available...

journal_title：Journal of diabetes

authors： Rolland C,Hession M,Murray S,Wise A,Broom I

更新日期：2009-09-01 00:00:00