The zDHHC family of S-acyltransferases.

Abstract:

:The discovery of the zDHHC family of S-acyltransferase enzymes has been one of the major breakthroughs in the S-acylation field. Now, more than a decade since their discovery, major questions centre on profiling the substrates of individual zDHHC enzymes (there are 24 ZDHHC genes and several hundred S-acylated proteins), defining the mechanisms of enzyme-substrate specificity and unravelling the importance of this enzyme family for cellular physiology and pathology.

journal_name

Biochem Soc Trans

authors

Lemonidis K,Werno MW,Greaves J,Diez-Ardanuy C,Sanchez-Perez MC,Salaun C,Thomson DM,Chamberlain LH

doi

10.1042/BST20140270

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

217-21

issue

2

eissn

0300-5127

issn

1470-8752

pii

BST20140270

journal_volume

43

pub_type

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