Abstract:
:An assessment of the role of marrow fat as a source of error in single energy quantitative CT (SEQCT) measurements of the spine is presented. Fat-induced shifts and spreads in SEQCT findings are discriminated and quantified. Studies using chemical analysis have reported an average vertebral bone mineral (MIN) loss of approximately 1.3 mg/ml (0.9%) per year from a peak MIN of 150 mg/ml at age 30 years with a standard error of the estimate (SEE) of approximately 23 mg/ml [coefficient of variation (CV) = 20%]; intraosseous vertebral fat content increases by approximately 2.4 mg/ml (1.4%) per year from a fat density of 175 mg/ml at age 30 years with an SEE of approximately 87.5 mg/ml (CV = 36%). If one does not adjust for the average age-related fat change, SEQCT underestimates MIN and overestimates MIN loss by 10-30% (at a scanner setting of approximately 80 kVp). Application of correction procedures reduces the average underestimation to 1-3%. The impact of residual vertebral fat variability on the accuracy of MIN measurements accounts for only 12-24% of the total accuracy error of typically 10-15 mg/ml. The impact of fat changes between zero and twice the normal age-related rate on MIN loss measurements on individual patients and patient groups (treatment versus control) accounts for only 1-2% of the total precision error of typically 1.5-3 mg/ml. From 94 to 99% of the spread of SEQCT versus age data is caused by sources of variability other than fat. All fat-related errors are higher than the above estimates by a factor of approximately 1.5-2.5 when scanning at higher voltages of up to 130 kVp. Given the limited impact of fat variability, we conclude that for most clinical applications, MIN and bone loss measurements should use SEQCT. Adjustment for the average under/overestimation (by either explicitly correcting SEQCT findings or by comparing them with normative data obtained on a similar scanner), measuring at low voltages of approximately 80 kVp, and strict compliance to quality assurance procedures are highly recommended to achieve optimum accuracy.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Glüer CC,Genant HKdoi
10.1097/00004728-198911000-00015subject
Has Abstractpub_date
1989-11-01 00:00:00pages
1023-35issue
6eissn
0363-8715issn
1532-3145journal_volume
13pub_type
杂志文章abstract::Masses arising in the adrenal gland may be simulated on computed tomography (CT) by a number of anatomical structures and variations, and by certain pathological conditions in adjacent organs. These adrenal pseudotumors include the following: fluid-filled gastric fundus, prominent splenic lobulations, upper pole renal...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198204000-00009
更新日期:1982-04-01 00:00:00
abstract:OBJECTIVE:We compared MRI with two-dimensional echocardiography (2dE) and Doppler echocardiography to determine the diagnostic role of MRI in hypertrophic cardiomyopathy (HCM). MATERIALS AND METHODS:Twenty-three patients with 2dE diagnosis of HCM were examined with MRI; 12 of 23 patients were also studied by color (cD...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199311000-00005
更新日期:1993-11-01 00:00:00
abstract::Maple syrup urine disease (MSUD) is an inherited metabolic disorder due to decreased decarboxylation of branched chain keto acids triggering an accumulation of leucine, isoleucine, and valine. We describe two infants with biochemically confirmed MSUD in whom computed tomography (CT) revealed cerebral edema. In one of ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198406000-00007
更新日期:1984-06-01 00:00:00
abstract:OBJECTIVE:The goal of this study was twofold: first, to quantify the influence of magnetic field strength (B0) on T2* and T2susceptibility relaxation rates in vertebral bone marrow; and second, to determine the significance of in-phase/out-of-phase phenomena in GE MRI as a function of TEs at different B0 values. MATER...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199505000-00023
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) on T2-weighted magnetic resonance imaging of liver parenchyma. METHODS:Forty-six patients with suspected hepatic tumors (group 1) underwent breath-hold T2-weighted fast spin echo imaging before and after 4 minu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181bc961b
更新日期:2010-03-01 00:00:00
abstract::Of 700 neonates examined by computed tomography (CT) in a 4 years period, 17 were found to have a posterior fossa hemorrhage. Eleven were born at term, and six were premature. Delivery was traumatic in 12 babies. The hematoma was in the subdural space in nine and within the cerebellum in eight. The CT diagnosis of ext...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198102000-00013
更新日期:1981-02-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility of a time-efficient, high-resolution magnetic resonance lymphangiography (HR MRL) protocol without image subtraction for the detection of lymphatic vessels in patients with primary and secondary lymphedema. METHODS:Three consecutive patients with lymphedema of the lower extremities ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章
doi:10.1097/01.rct.0000237814.33925.32
更新日期:2007-03-01 00:00:00
abstract::Although acute appendicitis is the most common disease of the appendix, the appendix can be involved by a wide range of diseases. Diseases other than acute appendicitis may produce signs and symptoms indistinguishable from those of acute appendicitis. Computed tomography (CT) can provide important information for diag...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200305000-00001
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVES:To characterize diffusion tensor imaging (DTI) tensor eigenvalues (λ1, λ2, λ3), fractional anisotropy, mean diffusivity, and radial diffusivity in healthy lumbar musculature. METHODS:Seventeen healthy subjects (10 men, 7 women; mean age, 28 ± 7 years) were scanned using a 3.0-T magnetic resonance imaging. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182772d66
更新日期:2013-01-01 00:00:00
abstract::The subarachnoid space continues into the orbit as part of the optic nerve sheath. This space varies in size but is usually tiny. Occasionally, prominent (one case in our experience) enhancement of the optic nerve as part of metrizamide computed tomography (CT) cisternography is seen on transverse and coronal scans pr...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197910000-00015
更新日期:1979-10-01 00:00:00
abstract::A 31-year-old woman with an aneurysmal bone cyst of the L1 vertebral body proved by biopsy and studied by plain lumbar spine roentgenography, radionuclide studies, myelography, and CT is presented. The unusual location of involvement of the vertebral body alone and the difficulty in differential diagnosis between aneu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198412000-00031
更新日期:1984-12-01 00:00:00
abstract::We report a case of nocardia choroid plexitis with extension into the parenchyma of the left parietal lobe in a previously well 13-year-old girl. The neuroimaging findings mimicked those of an intracranial neoplasm. This case illustrates the importance of including infectious etiologies in the differential diagnosis o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199405000-00025
更新日期:1994-05-01 00:00:00
abstract::We conducted a prospective evaluation of the normal vermiform appendix in 203 patients. Conventional CT techniques were utilized with an 8 mm slice thickness and 10 mm slice interval. The normal appendix was definitely identified in 51% of the patients studied. Computed tomographic appearance of the normal appendix is...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199107000-00009
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:Our goal was to elucidate the computed tomographic (CT) and clinicopathological features of inflammatory pseudotumor of the spleen. METHODS:Computed tomographic findings and clinic materials of 4 patients with inflammatory pseudotumor of the spleen were reviewed and compared with pathologic findings. RESULT...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000215
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the characteristics of lung cancers in patients with tuberculous fibrothorax or empyema. METHODS:We retrospectively evaluated 138 consecutive patients with a diagnosis of lung cancer combined with fibrothorax (n = 127) or empyema (n = 11) from January 2005 to May 2015. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000608
更新日期:2017-09-01 00:00:00
abstract::Helical CT is being increasingly used for the evaluation of suspected tracheal diseases. Although nonneoplastic and noninfectious diseases of the trachea are rare, their appearance on CT images may be highly suggestive of the diagnosis. High quality multiplanar and 3D reconstructions including 3D surface-shaded displa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200105000-00012
更新日期:2001-05-01 00:00:00
abstract::We present a case series of the MR findings of destructive tears of the Achilles tendon secondary to overlying soft tissue ulcerations. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200011000-00016
更新日期:2000-11-01 00:00:00
abstract::In children it is often necessary to ligate the splenic artery and the main collateral supply to the spleen during liver transplantation. The complication of splenic infarction has been observed on postoperative CT in such patients. The purpose of our study was to determine the incidence and CT appearance of splenic i...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199005000-00007
更新日期:1990-05-01 00:00:00
abstract::A method is outlined for obtaining direct longitudinal computed tomograms of the forearm using a conventional total body scanner. A case is described in which longitudinal scanning helped define a soft tissue tumor of the forearm and thereby assisted in surgical planning. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198102000-00029
更新日期:1981-02-01 00:00:00
abstract::Seven patients with polypoid mucoceles of the ethmoid sinuses were examined by computed tomography (CT). The findings in all cases were remarkably similar. This unique CT appearance has not been seen with malignancies and should be considered characteristic of this benign entity. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198208000-00010
更新日期:1982-08-01 00:00:00
abstract:PURPOSE:To retrospectively investigate the effect of the section thickness used for quantifying dual-energy perfusion computed tomography (DEpCT) during 2- and 3-dimensional evaluation. METHODS:Sixty-six patients (22 males and 44 females; mean age, 59.3 years) suspected of having an acute pulmonary embolism underwent ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000148
更新日期:2014-11-01 00:00:00
abstract::The diagnosis of abdominal actinomycosis is difficult because of its relative infrequency and imitation of other diseases. We present four cases in which these difficulties in diagnosis were experienced and show the utility of CT in suggesting this disease. Aspiration, biopsy, and proper culture technique, in conjunct...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198705000-00018
更新日期:1987-05-01 00:00:00
abstract::The magnetic resonance characteristics of 16 intracranial arachnoid cysts were evaluated and several features identified that allowed the differentiation from other cystic lesions. Uncomplicated arachnoid cyst contents respond like CSF to both T1 and T2 weighted sequences. Signal from the contiguous brain is of normal...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198703000-00007
更新日期:1987-03-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to evaluate the dependence of diffusion parameters on the b values adopted for intravoxel incoherent motion diffusion-weighted magnetic resonance imaging and to investigate the application value of multiple diffusion parameters obtained from monoexponential and biexponential models...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000569
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to study the role of multidetector computed tomography (MDCT) in the analysis of foreign objects found within or on the royal Egyptian mummies. METHODS:We studied MDCT images of 15 royal Egyptian mummies (1493-1156 BC) for the presence of foreign objects. We studied each found...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182ab2221
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:This study attempts to establish a quantitative link between a patient's body mass index (BMI), the delivered radiation dose, and the image noise. METHODS:The CARE Dose4D computed tomography (CT) acquisitions from 206 patients undergoing "eyes-to-thighs" contrast-enhanced positron emission tomography/CT studie...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318293d507
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:There is an ongoing debate about how to handle incidental findings (IF) detected in healthy individuals who participate in research-driven magnetic resonance imaging (MRI) studies. There are currently no established guidelines regarding their management. METHODS:We prospectively assessed the frequency of IF ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181d9c2bb
更新日期:2010-07-01 00:00:00
abstract::We present the case of a young man with compression of both renal arteries by the crura of the diaphragm. Correct diagnosis of renal artery entrapment is difficult but crucial. The investigations rely on an high index of suspicion and include Doppler ultrasound and spiral computed tomography angiography, which permits...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000250114.72338.5a
更新日期:2007-05-01 00:00:00
abstract::The primitive trigeminal artery is the most common of the persistent carotid-basilar anastomoses with an angiographic incidence of 0.6%. Fifteen cases of aneurysms of a persistent primitive trigeminal artery have been reported in the literature. A 16th patient is presented in whom an incidental trigeminal artery aneur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-198809010-00022
更新日期:1988-09-01 00:00:00
abstract:PURPOSE:Information regarding prostate blood flow as determined by positron emission tomography (PET) with H 0 may provide useful information about tumor diagnosis; however, PET requires a cyclotron for the production of an extremely short half-life (2 minutes) tracer. Therefore, the aim of this study was to propose a ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200207000-00005
更新日期:2002-07-01 00:00:00