当前位置： SCI文献检索 > GASTROINTESTINAL ENDOSCOPY期刊下所有文献 > Integrated diagnostic strategy for the invasion depth of early gastric cancer by conventional endoscopy and EUS.

Integrated diagnostic strategy for the invasion depth of early gastric cancer by conventional endoscopy and EUS.

Abstract：

BACKGROUND:Although conventional endoscopy (CE) and EUS are considered useful for predicting the invasion depth (T-staging) in early gastric cancer (EGC), no effective diagnostic strategy has been established. OBJECTIVE:To produce simple CE criteria and to elucidate an efficient diagnostic method by combining CE and EUS for accurate T-staging. DESIGN:Single-center retrospective analysis. SETTING:Academic university hospital. PATIENTS:Consecutive patients with EGC from April 2007 to March 2012 who underwent CE and EUS before treatment. INTERVENTIONS:Recorded endoscopic images were independently reviewed by 3 observers. The CE criteria for massive invasion were defined, and their utility and the additional value of EUS were assessed. MAIN OUTCOME MEASUREMENTS:The accuracy of CE based on the criteria and the accuracy of EUS. RESULTS:Two hundred thirty patients were enrolled: 195 with mucosal cancer or cancer in the submucosa less than 500 μm from the muscularis mucosae and 35 with invasive cancers. Multivariate analysis of the CE findings by 1 observer revealed that an irregular surface and a submucosal tumor-like marginal elevation were significantly associated with massive invasion. The simple CE criteria, consisting of those 2 features, had an overall accuracy of 73% to 82% and no significant differences in the diagnostic yield compared with EUS in all observers. CE accurately revealed mucosal cancer, and EUS efficiently salvaged the lesions that were over-diagnosed by CE. With our strategy, which involved the CE criteria and the optimal use of EUS, the comprehensive accuracy exceeded 85% in each observer. LIMITATIONS:Retrospective, single-center study. CONCLUSIONS:We demonstrated a practical strategy for T-staging in EGC using simple CE criteria and EUS.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Tsujii Y,Kato M,Inoue T,Yoshii S,Nagai K,Fujinaga T,Maekawa A,Hayashi Y,Akasaka T,Shinzaki S,Watabe K,Nishida T,Iijima H,Tsujii M,Takehara T

doi

10.1016/j.gie.2015.01.022

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

452-9

issue

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(15)00024-3

journal_volume

pub_type

杂志文章

在线工具

Integrated diagnostic strategy for the invasion depth of early gastric cancer by conventional endoscopy and EUS.