Abstract：
:As the extracellular matrix at the original site of a neuromuscular junction seems to play a major part in the specificity of synaptic regeneration, considerable attention has been paid to unique molecules localized to this region. Here we describe an extracellular matrix glycoprotein of the elasmobranch electric organ that is localized near the nerve endings. By immunological criteria, it is synthesized in the cell bodies, transported down the axons and is related to a glycoprotein in the synaptic vesicles of the neurones that innervate the electric organ. It is apparently specific for these neurones, as it cannot be detected elsewhere in the nervous system of the fish. Therefore, neurones seem to contribute unique extracellular matrix glycoproteins to the synaptic region. Synaptic vesicles could be involved in transporting these glycoproteins to or from the nerve terminal surface.
journal_name
Naturejournal_title
Natureauthors
Caroni P,Carlson SS,Schweitzer E,Kelly RBdoi
10.1038/314441a0subject
Has Abstractpub_date
1985-04-04 00:00:00pages
441-3issue
6010eissn
0028-0836issn
1476-4687journal_volume
314pub_type
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