Abstract:
BACKGROUND:Impaired spirometric parameters have been reported in patients with stage C heart failure and portend worse outcomes in these patients. The impact of spirometric parameters on outcomes in patients with stage D heart failure listed for heart transplantation is unknown. METHODS:We collected data on consecutive subjects listed for heart transplantation and examined the association of FEV1, FVC, and FEV1/FVC with (1) death or left ventricular assist device implantation (primary end point) and (2) death, left ventricular assist device implantation, or urgent transplantation (secondary end point). In a secondary analysis, we examined the association of baseline spirometry with post-transplant outcomes. RESULTS:Among 187 subjects (53 ± 10 y old, 17.1% women, 69.5% white subjects, 28.9% black subjects), there were 19 deaths, 28 left ventricular assist device implantations, and 74 urgent transplantations (primary end point of 25.1%, secondary end point of 64.7%) after a median of 5.5 months (interquartile range of 2.3-15.2). For FEV1, the hazard ratios for the primary and secondary end points were 0.93 (95% CI 0.61-1.41, P = .72) and 0.94 (95% CI 0.72-1.21, P = .62) per L, respectively. The hazard ratios of FVC were 0.90 (95% CI 0.65-1.25, P = .52) and 0.92 (95% CI 0.76-1.13, P = .43) per L, respectively. Impairment patterns (obstructive, restrictive, mixed) were not associated with risk for events. There was no interaction of spirometric parameters with smoking or lung disease for outcomes. Baseline spirometry was not associated with perioperative 30-d mortality (1.4%) and 1-y post-transplant survival (97.1%). CONCLUSIONS:In contrast to stage C subjects with heart failure, spirometric parameters were not associated with outcomes in this homogeneous stage D heart failure population.
journal_name
Respir Carejournal_title
Respiratory careauthors
Georgiopoulou VV,Deka A,Li S,Niazi AA,Farooq K,Kalogeropoulos AP,Butler J,Alexopoulos Ddoi
10.4187/respcare.03709subject
Has Abstractpub_date
2015-05-01 00:00:00pages
731-9issue
5eissn
0020-1324issn
1943-3654pii
respcare.03709journal_volume
60pub_type
杂志文章相关文献
Respiratory Care文献大全abstract:BACKGROUND:Confirmation of endotracheal tube (ETT) tip position and timely identification and correction of malposition is an essential component of care for endotracheally intubated and mechanically ventilated children. We evaluated the ability of a prototype optoacoustic medical device to determine ETT tip position. ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.06140
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Critically ill mechanically ventilated patients experience impaired airway clearance due to ineffective cough and impaired secretion mobilization. Cough augmentation techniques, including mechanical insufflation-exsufflation (MI-E), manually assisted cough, and lung volume recruitment, improve cough efficien...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04775
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Adaptive pressure control is a mode of mechanical ventilation where inflation pressure is adjusted by the ventilator to achieve a target tidal volume (VT). This means that as patient effort increases, inflation pressure is reduced, which may or may not be clinically appropriate. The purpose of this study was...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Field walking tests are commonly used in patients with chronic pulmonary diseases for assessment of functional capacity. However, the physiological demands and magnitude of desaturation on 6-min walk test (6MWT), incremental shuttle walk test (ISWT), and endurance shuttle walk test (ESWT) have not been inves...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.07171
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Diaphragm excursion is limited during respiratory maneuvers after a stroke. How the diaphragm is limited during reflexive coughs and affects the effectiveness of cough in stroke patients is unclear. This study aimed to measure reflexive cough strength by cough peak flow (CPF) induced by citric acid nebulizat...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.05488
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Users of home mechanical ventilation encounter major psychological and physiologic challenges. To ensure well-functioning home mechanical ventilation, users' experiences of care and treatment are important knowledge to supplement clinical perspectives. This systematic review aimed to summarize current qualit...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:10.4187/respcare.06855
更新日期:2019-09-01 00:00:00
abstract::Ventilator circuits should not be changed routinely for infection control purposes. The maximum duration of time that circuits can be used safely is unknown. Evidence is lacking related to ventilator-associated pneumonia (VAP) and issues of heated versus unheated circuits, type of heated humidifier, method for filling...
journal_title:Respiratory care
pub_type: 指南,杂志文章,实务指引
doi:
更新日期:2003-09-01 00:00:00
abstract::High-frequency oscillation (HFO), applied to either the airway or chest wall, has been associated with changes in sputum attributes and clearance. The evolution of evidence, both in vitro and in vivo, supporting the use of HFO is reviewed. Devices that apply HFO to the airway range from the relatively simple mechanica...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:True arterial blood samples are essential in making clinical decisions for respiratory patients. Previous studies using only the Portex Pro-Vent arterial sampler have shown a significant difference between arterial and venous filling times. The goal of this study was to determine whether there is a statistic...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.03480
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Readmission of mechanically ventilated patients to an ICU within 7 d reflects not only patient safety but also the quality of care of the ICU. This study aimed to investigate the risk and related factors for readmission to an ICU within 7 d in mechanically ventilated subjects. METHODS:A total of 658,452 mec...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.03868
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Current literature has been inconsistent in demonstrating that minimizing the duration of mechanical ventilation in very-low-birth-weight (VLBW) newborns reduces lung damage. OBJECTIVE:To determine if introduction of bubble nasal CPAP (bnCPAP), early surfactant treatment, and rapid extubation (combined bnCP...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01998
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Definite diagnosis of transudative or exudative pleural fluids often presents a diagnostic dilemma. The aim of this study was to evaluate whether amino-terminal brain natriuretic peptide (NT-proBNP) levels in pleural fluid has a diagnostic value for discriminating heart-failure-related pleural effusions from...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01818
更新日期:2013-02-01 00:00:00
abstract::Although some clinicians still believe that cystic fibrosis (CF) lung disease is largely due to hypersecretion of very viscous mucus, it has never been demonstrated that there is mucus hypersecretion in CF and it is clear that there is almost no intact mucin (the principal polymeric component of normal mucus) in CF sp...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:10.4187/002013209790983269
更新日期:2009-06-01 00:00:00
abstract::Computer-age technology is changing the face of respiratory therapy as it is that of nearly every other technical field. In some hospital respiratory therapy departments computers are presently being used for a wide range of functions such as blood gas result reporting, billing, budgeting, purchasing, hemodynamic calc...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract:BACKGROUND:Smoking is a serious problem in prisons. This work aimed to assess smoking-related behaviors and the effectiveness of tobacco cessation therapy in prison. METHODS:This study includes four visits to a prison in Bolvadin-Afyon, Turkey. Pharmacologic options for tobacco cessation were offered to the participan...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04122
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To investigate the predictive value of the maximal inspiratory pressure obtained by a digital vacuometer using a unidirectional valve (P(ImaxUV)) as to weaning outcome, and to compare its performance with the respiratory drive using airway occlusion pressure at 0.1 second (P(0.1)), and P(0.1)/P(ImaxUV). METH...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01489
更新日期:2012-08-01 00:00:00
abstract:HYPOTHESIS:We hypothesized that aerosol distribution in the lungs of patients with cystic fibrosis changes with positive expiratory pressure (PEP). METHODS:Eight patients were randomized to one of 2 conditions. On one study day, patients inhaled saline aerosol containing 99mtechnetium generated by a Pari LC Plus nebul...
journal_title:Respiratory care
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2005-11-01 00:00:00
abstract::Tracheostomy is one of the most common intensive care unit procedures performed. The advantages include patient comfort, safety, ability to communicate, and better oral and airway care. Patients may have shorter intensive care unit stays, days of mechanical ventilation, and hospital stays. There are risks, long-term a...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:The prevalence of obesity in developed countries is rising. Currently, Europe has a prevalence of 9-30% with significant impact on public health systems. Obese patients in ICUs require special management and treatment. Altered anatomy in obese patients complicates procedures such as mechanical ventilation. O...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04333
更新日期:2016-05-01 00:00:00
abstract:INTRODUCTION:There is no published standard for the ratio of staff to patients during exercise sessions in outpatient pulmonary rehabilitation. This lack of a standard raises concern about patient safety and the ability to monitor patients adequately. OBJECTIVE:Determine a staff-to-patient ratio standard by examining ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract:INTRODUCTION:Respiratory care is expensive and time-intensive, inappropriate care wastes resources, and failure to provide necessary and appropriate respiratory care may adversely affect patient outcomes. OBJECTIVE:To determine the appropriateness of basic respiratory care delivered at a 450-bed Veterans Affairs hospi...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Inhaled sedation is efficient and easily controllable; in low concentrations it causes minimal changes in the patient and very little interference with hemodynamics. Awakening after inhaled sedation is quick and predictable. The major reason inhaled sedation has not become widely used in intensive care is th...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:Improving quality of life (QOL) is a key goal in the care of patients with COPD. Pulmonary rehabilitation (PR) has clearly been shown to improve QOL, but is not accessible to many eligible patients. There is a need for alternative programs designed to improve patient well-being that are accessible to all pat...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04984
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Healthy individuals without respiratory symptoms can sometimes present with low FEV1/FVC. The objective of this study was to characterize and compare subjects without symptoms and with reduced FEV1/FVC but normal FEV1 with subjects with mild obstructive lung disease. METHODS:Fifty healthy subjects with FEV1...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.06131
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Emphysema and fibrosis, typically the idiopathic pulmonary fibrosis (IPF) form of usual interstitial pneumonia (UIP), can co-exist as combined pulmonary fibrosis emphysema (CPFE). It is unknown whether there is a pathobiologic basis for CPFE beyond the coexistence of fibrosis and emphysema. The aim of this s...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.03389
更新日期:2015-02-01 00:00:00
abstract::Functional residual capacity (FRC) is essentially the alveolar volume and a determinant of both oxygenation and respiratory system compliance (CRS). ARDS decreases FRC, and sufficient PEEP restores FRC; thus, assessments of PEEP by its impact on oxygenation and CRS are intimately linked. PEEP also can ameliorate or ag...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:10.4187/respcare.04657
更新日期:2016-06-01 00:00:00
abstract::The indications for heliox during mechanical ventilation are lower-airway obstruction, especially with hypercarbia; need to enhance aerosol delivery to lung periphery; and need to facilitate weaning from mechanical ventilation. Certain ventilators perform relatively well with heliox and are not substantially affected ...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Metered-dose inhalers with valved holding chambers (MDI-VHCs) have been shown to be equivalent to small-volume nebulizers (SVNs) for the delivery of bronchodilators in children. At Seattle Children's Hospital and Regional Medical Center we sought to implement the conversion from SVN to MDI-delivered albutero...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:COPD is one of the most common respiratory diseases. Patients with COPD experience and suffer from various physical and psychological symptoms. We performed this study to identify symptom clusters and the effects on quality of life (QOL) in patients with COPD. METHODS:A total of 130 COPD subjects were recru...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.05374
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Dynamic airway resistance from obstructive disease causes a concavity in the mid-expiratory portion of the spirometric flow-volume loop. We developed a simple model to measure the exponential decay in air flow during forced exhalation to quantify the extent of dynamic airway obstruction and facilitate the de...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04850
更新日期:2017-07-01 00:00:00