The association between manual mode defibrillation, pre-shock pause duration and appropriate shock delivery when employed by basic life support paramedics during out-of-hospital cardiac arrest.

Abstract:

BACKGROUND:Pre-shock pause duration of <20s is associated with improved survival after cardiac arrest. Manual mode defibrillation has been associated with the shortest duration of pre-shock pause but is largely practiced by advanced life support paramedics (ALS) whereas defibrillator only paramedics (basic life support or BLS) routinely use the defibrillator in automatic mode. OBJECTIVE:We sought to explore the relationship between manual mode defibrillation, pre-shock pause duration and rate of inappropriate shocks when defibrillation is provided by ALS vs. BLS trained in manual mode defibrillation. METHODS:We performed a retrospective review of all treated non-traumatic adult out-of-hospital cardiac arrest (OHCA) presenting in a shockable rhythm over a one year period beginning January 1, 2012. Our primary outcome measure was the proportion of manual mode shocks delivered by BLS with pre-shock pause duration of <20s when compared to ALS. Our secondary outcome measures were the duration of pre-, post- and peri-shock pause and the proportion of appropriate shocks (defined as correct identification and shock delivery to patients in a shockable rhythm) delivered by either level of paramedic. This study had a power of 90% to detect an absolute difference of 15% between paramedic levels in proportion of shocks delivered with pre-shock pause duration <20s. RESULTS:Among 2019 treated OHCA, 335 (20%) presented in a shockable rhythm. Manual defibrillation was performed in 155 (46%) of these cases (196 shocks by ALS, 143 shocks by BLS). There were no differences in the proportion of shocks delivered with pre-shock pause duration <20s (ALS 82.8% vs. BLS 84.8%, p=.65) nor pre-shock pause duration (s) (median, Q1, Q3); ALS: 12.0 (7.0,17.0) vs. BLS: 11.0 (5.0,17.0), p=.13 while BLS had a significantly shorter peri-shock pause duration (s) (median, Q1, Q3); ALS: 17.0 (12.0, 23.0) vs. BLS: 15.0 (9.0, 22.0), p=.05. There were no differences in the rate of inappropriate shocks (ALS 1.0% vs. BLS 0.7%), p=1.0 between levels of paramedics. CONCLUSIONS:Manual mode defibrillation by BLS paramedics produced similar measures of pre-shock pause duration when compared to ALS paramedics without increasing the incidence of inappropriate shocks. Further study is required to determine the potential impact of BLS manual mode defibrillation on clinical outcomes.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Cheskes S,Hillier M,Byers A,Verbeek PR,Drennan IR,Zhan C,Morrison LJ

doi

10.1016/j.resuscitation.2015.02.022

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

61-6

eissn

0300-9572

issn

1873-1570

pii

S0300-9572(15)00090-8

journal_volume

90

pub_type

杂志文章
  • Physicians' own preferences to the limitation and withdrawal of life-sustaining therapy.

    abstract::While limiting and forgoing therapy at the end of life is now accepted on medical, ethical, moral and legal grounds, many Americans continue to die with heroic measures being taken to prevent their death. Recent studies have demonstrated that physicians frequently attend to their patients without knowledge of their pr...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/s0300-9572(99)00114-8

    authors: Marik PE,Varon J,Lisbon A,Reich HS

    更新日期:1999-11-01 00:00:00

  • A comparison of European Trauma Registries. The first report from the EuroTARN Group.

    abstract:UNLABELLED:Trauma management systems have grown in response to regional variations in trauma population, geographical conditions and the provisions of care. National Trauma Registries are being established to improve patient outcomes. However international comparisons could provide the potential to record regional perf...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2007.06.023

    authors: Edwards A,Di Bartolomeo S,Chieregato A,Coats T,Della Corte F,Giannoudis P,Gomes E,Groenborg H,Lefering R,Leppaniemi A,Lossius HM,Ortenwal P,Roise O,Rusnak M,Sturms L,Smith M,Bondegaard Thomsen A,Willett K,Woodford M,

    更新日期:2007-11-01 00:00:00

  • Elevation of serum pancreatic secretory trypsin inhibitor following serious injury.

    abstract::Twenty-six of 31 seriously injured patients (84%) showed a marked elevation of serum pancreatic secretory trypsin inhibitor (PSTI) to more than twice the initial level within the first 2 weeks after admission. Serum PSTI rose from the second or third post-traumatic day and reached the maximum at day 5.8 on average. In...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(88)90043-3

    authors: Shibata T,Ogawa M,Takata N,Niinobu T,Uda K,Ukai T,Ohta M,Mori T

    更新日期:1988-07-01 00:00:00

  • Association of health insurance with post-resuscitation care and neurological outcomes after return of spontaneous circulation in out-of-hospital cardiac arrest patients in Korea.

    abstract:BACKGROUND:We investigated the association of health insurance status with post-resuscitation care and neurological recovery in out-of-hospital cardiac arrest (OHCA) and whether the effects changed with age or gender. METHODS:Adult OHCAs with presumed cardiac etiology who had sustained ROSC from 2013 to 2016 were enro...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2018.12.023

    authors: Kim TH,Ro YS,Shin SD,Song KJ,Hong KJ,Park JH,Kong SY

    更新日期:2019-02-01 00:00:00

  • PERK is activated differentially in peripheral organs following cardiac arrest and resuscitation.

    abstract::Visceral organs display differential sensitivity to ischemia and reperfusion injury, but the cellular mechanisms underlying these differential responses are not completely understood. A significant response to ischemia identified in brain is stress to the endoplasmic reticulum (ER), as indicated by PKR-like endoplasmi...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2005.03.014

    authors: Montie HL,Haezebrouck AJ,Gutwald JC,DeGracia DJ

    更新日期:2005-09-01 00:00:00

  • Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock.

    abstract::The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular e...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/0300-9572(89)90019-1

    authors: Miller VM,Vanhoutte PM

    更新日期:1989-12-01 00:00:00

  • No difference in mortality between men and women after out-of-hospital cardiac arrest.

    abstract:AIM:Comparing the outcome after out-of-hospital cardiac arrest (OHCA) in men and women and to determine whether sex modifies the effect of targeted temperature management (TTM) at 33 or 36°C. METHODS:The TTM trial randomized 950 patients to TTM at 33 or 36°C for 24h. This predefined sub-study of the TTM trial assessed...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.resuscitation.2015.06.030

    authors: Winther-Jensen M,Kjaergaard J,Wanscher M,Nielsen N,Wetterslev J,Cronberg T,Erlinge D,Friberg H,Gasche Y,Horn J,Hovdenes J,Kuiper M,Pellis T,Stammet P,Wise MP,Åneman A,Hassager C

    更新日期:2015-11-01 00:00:00

  • Statistical analysis of joint short-term and long-term survival in resuscitation research.

    abstract:OBJECTIVE:To develop statistical tools that use combined initial survival data and post-resuscitation survival data to test the null hypothesis that true, population-wide outcomes following experimental CPR interventions are not different from control. METHOD:A new test statistic, d(2), for evaluating Type 1 error is ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2007.04.026

    authors: Babbs CF

    更新日期:2007-11-01 00:00:00

  • The changes of brain water diffusion and blood flow on diffusion-weighted and perfusion-weighted imaging in a canine model of cardiac arrest.

    abstract:OBJECTIVE:To study the changes of brain water diffusion and cerebral haemodynamics of cortical areas using magnetic resonance imaging (MRI) in canine models of cardiac arrest (CA) and restoration of spontaneous circulation (ROSC). The secondary study objective was to evaluate whether MRI can be used to observe haemodyn...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2011.10.017

    authors: Liu R,Li X,Hu CL,Jiang L,Dai G,Wu GF,Huang GQ,Wei HY,Liao XX

    更新日期:2012-05-01 00:00:00

  • Comparison of brain computed tomography and diffusion-weighted magnetic resonance imaging to predict early neurologic outcome before target temperature management comatose cardiac arrest survivors.

    abstract:AIM:We previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest (CA). We compared the efficacy of brain computed tomography (CT) and DW-MRI ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2017.06.021

    authors: Jeon CH,Park JS,Lee JH,Kim H,Kim SC,Park KH,Yi KS,Kim SM,Youn CS,Kim YM,Lee BK

    更新日期:2017-09-01 00:00:00

  • Predictive power of serum NSE and OHCA score regarding 6-month neurologic outcome after out-of-hospital ventricular fibrillation and therapeutic hypothermia.

    abstract:AIM OF THE STUDY:To determine the predictive power of the out-of-hospital cardiac arrest (OHCA) score and serum neuron-specific enolase (NSE) in patients resuscitated from ventricular fibrillation treated with therapeutic hypothermia (TH) and glucose control. METHODS:An analysis of prospectively collected data of 90 T...

    journal_title:Resuscitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.resuscitation.2008.08.017

    authors: Oksanen T,Tiainen M,Skrifvars MB,Varpula T,Kuitunen A,Castrén M,Pettilä V

    更新日期:2009-02-01 00:00:00

  • Body mass index and outcomes of in-hospital ventricular tachycardia and ventricular fibrillation arrest.

    abstract:BACKGROUND:Due to higher transthoracic impedance, obese patients may be less likely to be successfully defibrillated from ventricular tachycardia or ventricular fibrillation (VT/VF) arrest. However, the association between patient body mass index (BMI), defibrillation success, and survival outcomes of VT/VF arrest are ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2016.05.028

    authors: Ogunnaike BO,Whitten CW,Minhajuddin A,Melikman E,Joshi GP,Moon TS,Schneider PM,Bradley SM,American Heart Association's Get With The Guidelines(®)-Resuscitation Investigators.

    更新日期:2016-08-01 00:00:00

  • Improving paediatric and newborn life support training by the use of modified manikins allowing airway occlusion.

    abstract::Manikins currently used in newborn and paediatric resuscitation training are limited in their effectiveness by an inability to allow instructors control over airway patency. This means that attempts to introduce situations that require interventions, other than just appropriate head positioning to achieve successful l...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/s0300-9572(02)00124-7

    authors: Madar J,Richmond S

    更新日期:2002-09-01 00:00:00

  • Determination of heart rate in the baby at birth.

    abstract::The International Liaison Committee on Resuscitation (ILCOR) publishes guidelines on neonatal resuscitation, which are evidence-based where possible. Initial assessment of heart rate, breathing and colour is an essential part of newborn resuscitation and the guidelines state that heart rate may be assessed using a ste...

    journal_title:Resuscitation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.resuscitation.2003.10.002

    authors: Owen CJ,Wyllie JP

    更新日期:2004-02-01 00:00:00

  • A new evaluation method for instructors of advanced cardiac life support.

    abstract::This study evaluated the ability of a specific educational program to teach instructors of advanced cardiac life support (ACLS) how to identify errors committed by team leaders of cardiac arrest simulations. The design compared experimental and control groups for differences in identification of critical performance e...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(86)90121-8

    authors: Goldman SL,Thompson B,Whitcomb J

    更新日期:1986-11-01 00:00:00

  • Effects of BLS training on factors associated with attitude toward CPR in college students.

    abstract:AIM:In order to elucidate the factors for willingness to perform CPR, we evaluated the responses of college students to questionnaires before and after basic life support (BLS) training. METHODS:Before and after participating in a small group BLS course, 259 students completed questionnaires. A logistic regression mod...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2008.11.023

    authors: Hamasu S,Morimoto T,Kuramoto N,Horiguchi M,Iwami T,Nishiyama C,Takada K,Kubota Y,Seki S,Maeda Y,Sakai Y,Hiraide A

    更新日期:2009-03-01 00:00:00

  • Neuroprotection with delayed initiation of prolonged hypothermia after in vitro transient global brain ischemia.

    abstract::Prolonged therapeutic hypothermia (32-34 degrees C for 12-24 h) improves the functional outcome of comatose cardiac arrest survivors. It is generally believed that rapidly achieving target temperature optimizes neuroprotection. However, this hypothesis has not been tested systematically. In this study, we compared the...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.07.016

    authors: Lawrence EJ,Dentcheva E,Curtis KM,Roberts VL,Siman R,Neumar RW

    更新日期:2005-03-01 00:00:00

  • Frequency and number of resuscitation related rib and sternum fractures are higher than generally considered.

    abstract:AIM OF THE STUDY:This study aimed to establish the incidence, number and location of CPR-related skeletal chest injuries (SCI) and to investigate the influence of age, gender, changes in resuscitation guidelines and technique of resuscitation. METHODS:We analysed SCI in 2148 patients who had undergone resuscitation fo...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2015.02.034

    authors: Kralj E,Podbregar M,Kejžar N,Balažic J

    更新日期:2015-08-01 00:00:00

  • The predictive value of soluble urokinase plasminogen activator receptor (SuPAR) regarding 90-day mortality and 12-month neurological outcome in critically ill patients after out-of-hospital cardiac arrest. Data from the prospective FINNRESUSCI study.

    abstract:AIM:The whole body ischaemia-reperfusion after cardiac arrest (CA) induces a systemic inflammation-reperfusion response. The expression of urokinase plasminogen activator receptor (uPAR) is known to be induced after hypoxia and increased levels of soluble form suPAR have been measured after hypoxia and ischaemia. Our a...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2014.08.017

    authors: Jalkanen V,Vaahersalo J,Pettilä V,Kurola J,Varpula T,Tiainen M,Huhtala H,Alaspää A,Hovilehto S,Kiviniemi O,Kuitunen A,Tenhunen J,FINNRESUSCI LAB STUDY GROUP.

    更新日期:2014-11-01 00:00:00

  • The epidemiology of non-traumatic prehospital sudden death in Macau.

    abstract:OBJECTIVE:To understand the epidemiology of non-traumatic prehospital sudden death (NPSD) in Macau, and to discuss potential diseases related to NPSD. METHODS:We analysed the epidemiological characteristics of 605 NPSD cases occurred between January 1, 2003 and December 31, 2005 in Macau. Four hundred NPSD victims' me...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2007.01.011

    authors: Wang H,Lei W,Li Y,Xu T

    更新日期:2007-08-01 00:00:00

  • Systematic review and meta-analysis of hemodynamic-directed feedback during cardiopulmonary resuscitation in cardiac arrest.

    abstract:BACKGROUND/OBJECTIVE:Physiologic monitoring of resuscitative efforts during cardiac arrest is gaining in importance, as it provides a real-time window into the cellular physiology of patients. The aim of this review is to assess the quality of evidence surrounding the use of physiologic monitoring to guide cardiopulmon...

    journal_title:Resuscitation

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.resuscitation.2016.01.025

    authors: Chopra AS,Wong N,Ziegler CP,Morrison LJ

    更新日期:2016-04-01 00:00:00

  • Lightning, sudden cardiac death, simulation and an automated external defibrillator: the perfect storm.

    abstract::This is a report of an 11-year-old boy who had sudden cardiac death after a lightning strike while playing lacrosse at summer camp. The camp staff had performed weekly drills to prepare for various medical emergencies and quickly activated their "Emergency Activation System". The child received immediate cardiopulmona...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2007.02.005

    authors: Nelson KL,Mills W Jr,Umbel S,Crosson JE,Shaffner DH,Hunt EA

    更新日期:2007-09-01 00:00:00

  • Compression characteristics of CPR manikins.

    abstract::We evaluated the force-depth compression characteristics of 8 different CPR manikins during mechanical cardiopulmonary resuscitation by a thumper. The force required to compress the manikin's thorax of 1, 2, 3, 4 and 5 cm was measured. It ranged between 6.3 and 14 kp at a depth of 1 cm, 11.6-30 kp at 2 cm, 17-38 kp at...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(95)00874-s

    authors: Baubin MA,Gilly H,Posch A,Schinnerl A,Kroesen GA

    更新日期:1995-10-01 00:00:00

  • The immediate life support (ILS) course--the Italian experience.

    abstract:AIM OF THE STUDY:The 1-day immediate life support course (ILS) was started in the United Kingdom and adopted by the ERC to train healthcare professionals who attend cardiac arrests only occasionally. Currently, there are no reports about the ILS course from outside the UK. In this paper we describe our initial Italian ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2006.07.024

    authors: Scapigliati A,Sanna T,Zamparelli R,Sandroni C,Colizzi C,Fenici P,Arlotta G,Nuzzo C,Bonarrigo C,Bellocci F,Schiavello R,Possati G

    更新日期:2007-03-01 00:00:00

  • Cold water submersion and cardiac arrest in treatment of severe hypothermia with cardiopulmonary bypass.

    abstract::In the paediatric population, submersion injury with drowning or near-drowning represents a significant cause of morbidity and mortality. This study reviews retrospectively our own experiences and the literature on the use of cardiopulmonary bypass (CPB) to rewarm paediatric victims of cold water submersion who suffer...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/s0300-9572(01)00474-9

    authors: Wollenek G,Honarwar N,Golej J,Marx M

    更新日期:2002-03-01 00:00:00

  • Does lying in the recovery position increase the likelihood of not delivering cardiopulmonary resuscitation?

    abstract:BACKGROUND:Resuscitation guidelines endorse unconscious and normally breathing out-of-hospital victims to be placed in the recovery position to secure airway patency, but recently a debate has been opened as to whether the recovery position threatens the cardiac arrest victim's safety assessment and delays the start of...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2017.03.008

    authors: Freire-Tellado M,Navarro-Patón R,Pavón-Prieto MDP,Fernández-López M,Mateos-Lorenzo J,López-Fórneas I

    更新日期:2017-06-01 00:00:00

  • The beneficial effect of basic life support on ventricular fibrillation mean frequency and coronary perfusion pressure.

    abstract:BACKGROUND AND OBJECTIVE:Chest compressions before initial defibrillation attempts have been shown to increase successful defibrillation. This animal study was designed to assess whether ventricular fibrillation mean frequency after 90 s of basic life support cardiopulmonary resuscitation (CPR) may be used as an indica...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/s0300-9572(01)00388-4

    authors: Achleitner U,Wenzel V,Strohmenger HU,Lindner KH,Baubin MA,Krismer AC,Mayr VD,Amann A

    更新日期:2001-11-01 00:00:00

  • Efficacy of therapeutic hypothermia after out-of-hospital cardiac arrest due to ventricular fibrillation.

    abstract:AIM OF THE STUDY:We investigated implementation and efficacy of mild therapeutic hypothermia in the treatment of out-of-hospital cardiac arrest due to ventricular fibrillation. MATERIALS AND METHODS:Two periods were compared, an historical one (36 patients) between 2000 and 2002 where therapeutic hypothermia was never...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2007.04.014

    authors: Belliard G,Catez E,Charron C,Caille V,Aegerter P,Dubourg O,Jardin F,Vieillard-Baron A

    更新日期:2007-11-01 00:00:00

  • Aerosol generation during chest compression and defibrillation in a swine cardiac arrest model.

    abstract:AIM:It remains unclear whether cardiac arrest (CA) resuscitation generates aerosols that can transmit respiratory pathogens. We hypothesize that chest compression and defibrillation generate aerosols that could contain the SARS-CoV-2 virus in a swine CA model. METHODS:To simulate witnessed CA with bystander-initiated ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2020.12.004

    authors: Hsu CH,Tiba MH,Boehman AL,McCracken BM,Leander DC,Francalancia SC,Pickell Z,Sanderson TH,Ward KR,Neumar RW

    更新日期:2020-12-15 00:00:00

  • Should there be a change in the teaching of airway management in the medical school curriculum?

    abstract:OBJECTIVE:To evaluate the use of the Laryngeal Mask Airway (LMA), the oesophageal-tracheal combitube (ETC) and the tracheal tube (TT) by medical students, with a view to recommend changes to the medical school curriculum. METHODS:A prospective cohort study of 93 third-year medical students were taught the use of LMA, ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.07.011

    authors: Tiah L,Wong E,Chen MF,Sadarangani SP

    更新日期:2005-01-01 00:00:00