Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels.

abstract：:For nearly a century, researchers have tried to understand the swimming of aquatic animals in terms of a balance between the forward thrust from swimming movements and drag on the body. Prior approaches have failed to provide a separation of these two forces for undulatory swimmers such as lamprey and eels, where most...

journal_title：Scientific reports

authors： Bale R,Shirgaonkar AA,Neveln ID,Bhalla AP,MacIver MA,Patankar NA

更新日期：2014-12-10 00:00:00

abstract：:We developed a time-efficient semi-automated axon quantification method using freeware in human cranial nerve sections stained with paraphenylenediamine (PPD). It was used to analyze a total of 1238 facial and masseteric nerve biopsies. The technique was validated by comparing manual and semi-automated quantification ...

journal_title：Scientific reports

authors： Engelmann S,Ruewe M,Geis S,Taeger CD,Kehrer M,Tamm ER,Bleys RLAW,Zeman F,Prantl L,Kehrer A

更新日期：2020-02-06 00:00:00

abstract：:Lophatheri Herba (LH), dried leaf of Lophatherum gracile Brongn, has long been used to reduce thirst and treat fever and inflammation in Chinese medicine. Recent studies have shown that LH has anti-viral, anti-bacterial, anti-cancer, anti-oxidant, diuretic, and hyperglycemic properties. However, the effects of an etha...

journal_title：Scientific reports

authors： Kim A,Im M,Gu MJ,Ma JY

更新日期：2016-11-03 00:00:00

abstract：:Fourier ptychographic microscopy (FPM) is a novel computational coherent imaging technique for high space-bandwidth product imaging. Mathematically, Fourier ptychographic (FP) reconstruction can be implemented as a phase retrieval optimization process, in which we only obtain low resolution intensity images correspond...

journal_title：Scientific reports

authors： Bian L,Suo J,Chung J,Ou X,Yang C,Chen F,Dai Q

更新日期：2016-06-10 00:00:00

abstract：:Endoluminal surgery for the treatment of colorectal neoplasia is typically carried out using electrocautery tools which imply limited precision and the risk of harm through collateral thermal damage to the adjacent healthy tissue. As a potential alternative, we present the successful colonic epithelial laser ablation ...

journal_title：Scientific reports

authors： Beck RJ,Bitharas I,Hand DP,Maisey T,Moore AJ,Shires M,Thomson RR,West NP,Jayne DG,Shephard JD

更新日期：2020-11-20 00:00:00

abstract：:The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contrast to Noise Ratio (CNR), while minimizing the radiological risks,...

journal_title：Scientific reports

authors： Delogu P,Di Trapani V,Brombal L,Mettivier G,Taibi A,Oliva P

更新日期：2019-09-11 00:00:00

abstract：:The application of a lattice structure in the lightweight design of compressor impellers can reduce their mass and moment of inertia, hence improving the effective carrying of aircraft and reducing the start and braking moments of the impeller. The feasibility of a processing-lattice compressor impeller is the prerequ...

journal_title：Scientific reports

authors： Jia D,Li F,Zhang Y

更新日期：2020-01-17 00:00:00

abstract：:The evolution of sexual reproduction remains a fascinating enigma in biology. Theoretically, populations of sexual organisms investing half of their resources into producing male offspring that don't contribute to reproduction should grow at only half the rate of their asexual counterparts. This demographic disadvanta...

journal_title：Scientific reports

authors： Kobayashi K,Hasegawa E

更新日期：2016-04-01 00:00:00

abstract：:The combustion of candles exhibits a variety of dynamical behaviors. Binding several candles together will result in flickering of candle flames, which is generally described as a nonlinear oscillator. The impact on the frequency of the flame by several factors, such as the arrangement, the number and the asymmetry of...

journal_title：Scientific reports

authors： Chen T,Guo X,Jia J,Xiao J

更新日期：2019-01-23 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease. Increasing the chances of success for future clinical strategies requires more in-depth knowledge of the molecular basis underlying disease heterogeneity. We recently laid the foundation for a molecular taxonomy of ALS by whole-ge...

journal_title：Scientific reports

authors： Morello G,Guarnaccia M,Spampinato AG,Salomone S,D'Agata V,Conforti FL,Aronica E,Cavallaro S

更新日期：2019-07-10 00:00:00

abstract：:Ocean warming (OW) and acidification (OA) are key features of global change and are predicted to have negative consequences for marine species and ecosystems. At a smaller scale increasing oil and gas activities at northern high latitudes could lead to greater risk of petroleum pollution, potentially exacerbating the ...

journal_title：Scientific reports

authors： Arnberg M,Calosi P,Spicer JI,Taban IC,Bamber SD,Westerlund S,Vingen S,Baussant T,Bechmann RK,Dupont S

更新日期：2018-11-26 00:00:00

abstract：:Plasmodiophora brassicae causes clubroot, a major disease of Brassica oil and vegetable crops worldwide. P. brassicae is a Plasmodiophorid, obligate biotrophic protist in the eukaryotic kingdom of Rhizaria. Here we present the 25.5 Mb genome draft of P. brassicae, developmental stage-specific transcriptomes and a tran...

journal_title：Scientific reports

authors： Schwelm A,Fogelqvist J,Knaust A,Jülke S,Lilja T,Bonilla-Rosso G,Karlsson M,Shevchenko A,Dhandapani V,Choi SR,Kim HG,Park JY,Lim YP,Ludwig-Müller J,Dixelius C

更新日期：2015-06-18 00:00:00

abstract：:Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...

journal_title：Scientific reports

authors： Söldner CA,Horn AHC,Sticht H

更新日期：2018-03-29 00:00:00

abstract：:Transfer printing, a two-step process (i.e. picking up and printing) for heterogeneous integration, has been widely exploited for the fabrication of functional electronics system. To ensure a reliable process, strong adhesion for picking up and weak or no adhesion for printing are required. However, it is challenging ...

journal_title：Scientific reports

authors： Sim K,Chen S,Li Y,Kammoun M,Peng Y,Xu M,Gao Y,Song J,Zhang Y,Ardebili H,Yu C

更新日期：2015-11-10 00:00:00

abstract：:Fracture of initially crack-free bodies often occurs due to plastic instabilities known as shear bands. Previous computer simulations advanced a myriad of mechanisms to rationalize shear banding. However, they were restricted to planar geometries. We investigate the relevance of anisotropic plasticity by picking an ax...

journal_title：Scientific reports

authors： Benzerga AA,Thomas N,Herrington JS

更新日期：2019-02-05 00:00:00

abstract：:Acute kidney injury (AKI) in patients with septic shock is associated with high mortality, but the appropriate timing for initiating continuous renal replacement therapy (CRRT) is controversial. We retrospectively enrolled 158 septic shock patients with AKI in the medical intensive care unit (ICU) from July 2016 to Ap...

journal_title：Scientific reports

authors： Yoon BR,Leem AY,Park MS,Kim YS,Chung KS

更新日期：2019-08-19 00:00:00

abstract：:The interplay between spin states and metallization in compressed CoCl2 is investigated by combining diffraction, resistivity and spectroscopy techniques under high-pressure conditions and ab-initio calculations. A pressure-induced metallization along with a Co2+ high-spin (S = 3/2) to low-spin (S = 1/2) crossover tra...

journal_title：Scientific reports

authors： Barreda-Argüeso JA,Nataf L,Aguado F,Hernández I,González J,Otero-de-la-Roza A,Luaña V,Jia Y,Jin C,Kim B,Kim K,Min BI,Heribert W,Jephcoat AP,Rodríguez F

更新日期：2019-04-01 00:00:00

abstract：:Engineered Terahertz (THz) metamaterials presented an unique characteristics for biosensing application due to their accurately tunable resonance frequency, which is in accord with vibrational frequency of some important biomolecules such as cancer biomarker. However, water absorption in THz regime is an obstacle to e...

journal_title：Scientific reports

authors： Geng Z,Zhang X,Fan Z,Lv X,Chen H

更新日期：2017-11-27 00:00:00

abstract：:Leukocyte-platelet rich fibrin (L-PRF) is extensively used in the dentistry field and other clinical scenarios due to its regeneration properties. The goal of the present study was to depict the L-PRF secretome and how it changes over time. We obtained L-PRF membranes and cultured them in DMEM. The secretome was colle...

journal_title：Scientific reports

authors： Hermida-Nogueira L,Barrachina MN,Morán LA,Bravo S,Diz P,García Á,Blanco J

更新日期：2020-09-03 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) still presents complications: paravalvular leakage (PVL) and onset of conduction abnormalities leading to permanent pacemaker implantation. Our aim was testing a validated patient-specific computational framework for prediction of TAVI outcomes and possible complications....

journal_title：Scientific reports

authors： Bosi GM,Capelli C,Cheang MH,Delahunty N,Mullen M,Taylor AM,Schievano S

更新日期：2020-06-18 00:00:00

abstract：:Transposable elements are emerging as an important source of cis-acting regulatory sequences and epigenetic marks that could influence gene expression. However, few studies have dissected the role of specific transposable element insertions on epigenetic gene regulation. Bari-Jheh is a natural transposon that mediates...

journal_title：Scientific reports

authors： Guio L,Vieira C,González J

更新日期：2018-08-15 00:00:00

abstract：:This is the first study to demonstrate that colour transformations in the volume of a photochromic material (PM) are induced at the intersections of two control light channels, one controlling PM colouration and the other controlling decolouration. Thus, PM colouration is induced by position selectivity, and therefore...

journal_title：Scientific reports

authors： Hirayama R,Shiraki A,Naruse M,Nakamura S,Nakayama H,Kakue T,Shimobaba T,Ito T

更新日期：2016-08-16 00:00:00

abstract：:Male infertility is a worldwide medical problem. Asthenozoospermia is a common cause of infertility. Epigenetic modifications of DNA and histones have been shown to influence human infertility, but no research has explored whether N(6)-methyladenosine (m(6)A) level in RNA is associated with asthenozoospermia. Here, we...

journal_title：Scientific reports

authors： Yang Y,Huang W,Huang JT,Shen F,Xiong J,Yuan EF,Qin SS,Zhang M,Feng YQ,Yuan BF,Liu SM

更新日期：2016-04-13 00:00:00

abstract：:Moisture in materials can be a source of future outgassing and exacerbate unwanted changes in physical and chemical properties. Here, we investigate the effect of sample size and shape on the moisture transport phenomena through a combined experimental and modeling approach. Several different materials varying in size...

journal_title：Scientific reports

authors： Sharma HN,Sun Y,Glascoe EA

更新日期：2020-10-20 00:00:00

abstract：:We aimed to establish the collective influence of four lifestyle practices (physical activity, diet, smoking and alcohol consumption) on the prevalence and incidence of AMD. At baseline, 2428 participants aged 49+ with complete lifestyle and AMD data were examined, and of these, 1903 participants were re-examined 15 y...

journal_title：Scientific reports

authors： Gopinath B,Liew G,Flood VM,Joachim N,Burlutsky G,Mitchell P

更新日期：2017-06-28 00:00:00

abstract：:Coffee contains caffeine and diterpenes that were associated with decreased breast cancer risk, but results remained inconsistent. The study purpose was to investigate the associations between coffee products and breast cancer risk among Hong Kong Chinese women. We conducted a hospital-based case-control study in thre...

journal_title：Scientific reports

authors： Lee PMY,Chan WC,Kwok CC,Wu C,Law SH,Tsang KH,Yu WC,Yeung YC,Chang LDJ,Wong CKM,Wang F,Tse LA

更新日期：2019-09-03 00:00:00

abstract：:Self-organization and pattern formation in network-organized systems emerges from the collective activation and interaction of many interconnected units. A striking feature of these non-equilibrium structures is that they are often localized and robust: only a small subset of the nodes, or cell assembly, is activated....

journal_title：Scientific reports

authors： Nicolaides C,Juanes R,Cueto-Felgueroso L

更新日期：2016-02-17 00:00:00

abstract：:New strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of eliciting human immune responses. Using genome-wide transcriptomics of Mtb in...

journal_title：Scientific reports

authors： Coppola M,van Meijgaarden KE,Franken KL,Commandeur S,Dolganov G,Kramnik I,Schoolnik GK,Comas I,Lund O,Prins C,van den Eeden SJ,Korsvold GE,Oftung F,Geluk A,Ottenhoff TH

更新日期：2016-11-28 00:00:00

abstract：:Recent studies have demonstrated functions of miR-145 in vascular smooth muscle cells (VSMCs) phenotypes and vascular diseases. In this study, we aim to determine whether CD40 is involved in miR-145 mediated switch of VSMC phenotypes. In cultured VSMCs, the effects of miR-145 and CD40 on TNF-α, TGF-β, and Homocysteine...

journal_title：Scientific reports

authors： Guo X,Li D,Chen M,Chen L,Zhang B,Wu T,Guo R

更新日期：2016-10-12 00:00:00

abstract：:The ability of marine invertebrate larvae to control their vertical position shapes their dispersal pattern. In species characterized by large variations in population density, like many echinoderm species, larval dispersal may contribute to outbreak and die-off phenomena. A proliferation of the ophiuroid Ophiocomina ...

journal_title：Scientific reports

authors： Guillam M,Bessin C,Blanchet-Aurigny A,Cugier P,Nicolle A,Thiébaut É,Comtet T

更新日期：2020-07-21 00:00:00