Abstract:
OBJECTIVE:The aim of the study was to establish optimal diagnostic and therapeutic scheme and to assess the efficacy of intrauterine therapy of hydrocephalus. MATERIAL AND METHODS:The study was carried out between 1992-2012 on the total of 222 fetuses with hydro- cephalus, using Orbis-Sigma and ACCU-Flow valves (168 cases) and Cook8 shunts, according to a strictly defined diagnostic and therapeutic scheme. RESULTS:In the first stage of the study (between 1992-2001), a total of 168 fetuses with prenatally diagnosed hydrocephalus received intrauterine therapy In 91.6% of the cases the therapy resulted in a decreased size of cerebral ventricles. The valve dislocated in 23 cases (13.6%). Preterm delivery occurred in 44% of the affected neonates. Severe mental impairment occurred in 17.76%, average in 36.8%, and slight in 32.9% of the infants. Normal mental development at the age of 3 was observed in 12.5% of the children. A total of 11.2% of chldren did not require further neurosurgical treatment. In the second stage of the study (between 2006-2012) after therapy the size of the right lateral cerebral ventricle decreased by 54.76% (average of27.54 mm to 12.46 mm) and the left lateral cerebral ventricle decreased by 53.12% (average of 26.41 mm to 12.38 mm) (p=0.0018). The maximum and minimum width of the cerebral cortex increased by 23.06% and 27% (average of 9.04 mm to 11.75 mm vs. 3.65 mm to 5 mm), respectively Early complications were observed in 22% of the cases: PROM (6), intrauterine fetal death (4), intrauterine infection (1), and premature detachment of the placenta (1). Average gestational age at delivery was 34 weeks, and 24% of the patients delivered at term. CONCLUSIONS:Implantation of ventriculoamniotic shunts proved to be an effective form of therapy resulting in normalization of intracranial pressure. In both stages of therapy reduction of ventricular size in patients with hydrocephalus and good neurological outcome (45.4% in I stage, 60% in II stage) were observed. In the second stage of therapy the size of lateral brain ventricles after fetal therapy was significantly lower (54%). A total of 18% of the neonates did not require neurosurgical treatment.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Szaflik K,Czaj M,Polis L,Wojtera J,Szmański W,Krzeszowski W,Polis B,Litwińska M,Mikolajczyk W,Janiak K,Maroszyńska I,Gulczyńska Esubject
Has Abstractpub_date
2014-12-01 00:00:00pages
16-22issue
12eissn
0017-0011issn
2543-6767journal_volume
85pub_type
杂志文章abstract::Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fe...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract::An increase in alpha-amylase activity with parallel decrease in glucose concentration in amniotic fluid is observed during pregnancy. This interdependence is a theoretical basis for using an alpha-amylase/glucose index in fetal maturity evaluation. The aim of the study was to investigate usefulness of the alpha-amylas...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Selected clinical features of the course of pregnancy in 118 gravidas with placenta praevia diagnosed ultrasonographically on the first breeding were compared. The clinical features significantly connected with bleeding and the prognostic features for the way of delivery were stated. The longest bleeding was observed ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract:AIM:To assess the correlation between homocysteine concentrations and gestational age, gender Apgar score, complications in pregnancy delivery modalities and levels of vitamin B12 and foliate. MATERIAL AND METHODS:Concentration of homocysteine, vitamins-B12, foliate were measured in cord blood and mother blood. There ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::Basic methods of contraception of unwanted pregnancy are reviewed: mechanical, vaginal devices, hormonal tablets, and IUDs. On the basis of personal experience the author considers that, compared with other methods of contraception, the intrauterine spiral is the safest device for the female organism. An evaluation...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract:OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2018.0102
更新日期:2018-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:We investigated how maternal endothelial function is affected by pregestational (Type 1) diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) and/or chronic hypertension (chHT) or gestational hypertension (PIH). METHODS:We conducted a prospective, observational study involving 78 participants wit...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/62209
更新日期:2016-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-12-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2007-10-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1893
更新日期:2015-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:10.17772/gp/60973
更新日期:2016-01-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-02-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/60550
更新日期:2015-12-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2004-03-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00