Abstract:
:The cortisol level in fingernails may reflect the hormone's cumulative production over a long period, but the notions have not been fully established. In this study, we investigated the association of cortisol in fingernails with cortisol accumulation over a long period (hair cortisol) and over a relatively short period (salivary cortisol). In study 1, hair and fingernail samples were collected from 58 middle-aged and elderly men. The cortisol level in hair samples was moderately associated with the level in fingernail samples (r = 0.29, p < 0.05 and rs = 0.36, p < 0.01). In study 2, 37 workers provided 4 saliva samples over the course of one day (at awakening, 30 min after awakening, before lunch, and after work) and another set a month later. Further, the workers were asked to provide fingernail samples during a six-month period. We found that the cortisol level in saliva over the whole day (area under the curve for cortisol) was moderately associated with the cortisol level measured in fingernail samples that were collected 4 months (r = 0.43, p < 0.05 and rs = 0.50, p < 0.01) and 5 months later (r = 0.45, p < 0.05 and rs = 0.53, p < 0.01). These results indicated that the cortisol level in fingernail samples might retrospectively represent hormone production during a given period. The cortisol level in fingernail samples may be useful in the investigation of the link between psychosocial stress and health.
journal_name
Psychoneuroendocrinologyjournal_title
Psychoneuroendocrinologyauthors
Izawa S,Miki K,Tsuchiya M,Mitani T,Midorikawa T,Fuchu T,Komatsu T,Togo Fdoi
10.1016/j.psyneuen.2015.01.015subject
Has Abstractpub_date
2015-04-01 00:00:00pages
24-30eissn
0306-4530issn
1873-3360pii
S0306-4530(15)00029-3journal_volume
54pub_type
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journal_title:Psychoneuroendocrinology
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