Abstract:
:Thousands of long noncoding RNAs (lncRNAs) have been discovered, but their functional characterization has been slowed by a limited set of research tools. Here we review emerging RNA-centric methods to interrogate the intrinsic structure of lncRNAs as well as their genomic localization and biochemical partners. Understanding these technologies, including their advantages and caveats, and developing them in the future will be essential to progress from description to comprehension of the myriad roles of lncRNAs.
journal_name
Nat Struct Mol Bioljournal_title
Nature structural & molecular biologyauthors
Chu C,Spitale RC,Chang HYdoi
10.1038/nsmb.2921subject
Has Abstractpub_date
2015-01-01 00:00:00pages
29-35issue
1eissn
1545-9993issn
1545-9985pii
nsmb.2921journal_volume
22pub_type
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