Abstract:
:Drug delivery nanocarriers, especially targeted drug delivery by liposomes are emerging as a class of therapeutics for cancer. Early research results suggest that liposomal therapeutics enhanced efficacy, while simultaneously reducing side effects, owing to properties such as more targeted localization in tumors and active cellular uptake. Here, we highlight the features of immunoliposomes that distinguish them from previous anticancer therapies, and describe how these features provide the potential for therapeutic effects that are not achievable with other modalities. While a large number of studies has been published, the emphasis here is placed on the carbonic anhydrase IX (CA-IX) and the conjugated liposomes that are likely to open a new chapter on drug delivery system by using immunoliposomes to deliver anticancer ingredients to cancer cells in vivo.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Ng HL,Lu A,Lin G,Qin L,Yang Zdoi
10.3390/ijms16010230subject
Has Abstractpub_date
2014-12-24 00:00:00pages
230-55issue
1issn
1422-0067pii
ijms16010230journal_volume
16pub_type
杂志文章,评审abstract::A split plot 3 by 4 experiment was designed to characterize the relationship between production of gluthatione (GSH), oxidized gluthatione (GSSG), total flavonoid, anthocyanin, ascorbic acid and antioxidant activities (FRAP and DPPH) in three varieties of Labisia pumila Blume, namely the varieties alata, pumila and la...
journal_title:International journal of molecular sciences
pub_type: 杂志文章
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abstract::Increasing evidence has shown that many chronic diseases originate from early life, even before birth, through what are termed as fetal programming effects. Glucocorticoids are frequently used prenatally to accelerate the maturation of the lungs of premature infants. High-fat diets are associated with insulin resistan...
journal_title:International journal of molecular sciences
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abstract::Following major advances in the field of medicinal chemistry, novel drugs can now be designed systematically, instead of relying on old trial and error approaches. Current drug design strategies can be classified as being either ligand- or structure-based depending on the design process. In this paper, by describing t...
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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doi:10.3390/ijms16047320
更新日期:2015-04-01 00:00:00
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journal_title:International journal of molecular sciences
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更新日期:2019-05-18 00:00:00
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,meta分析,评审
doi:10.3390/ijms20194851
更新日期:2019-09-30 00:00:00
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journal_title:International journal of molecular sciences
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doi:10.3390/ijms21051702
更新日期:2020-03-02 00:00:00
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms17030431
更新日期:2016-03-22 00:00:00
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2017-11-15 00:00:00
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journal_title:International journal of molecular sciences
pub_type: 已发布勘误
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
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更新日期:2016-12-10 00:00:00
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journal_title:International journal of molecular sciences
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journal_title:International journal of molecular sciences
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更新日期:2017-02-03 00:00:00
abstract::Neurodegenerative diseases may have distinct genetic etiologies and pathological manifestations, yet share common cellular mechanisms underpinning neuronal damage and dysfunction. These cellular mechanisms include excitotoxicity, calcium dysregulation, oxidative damage, ER stress and neuroinflammation. Recent data hav...
journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms17081332
更新日期:2016-08-12 00:00:00
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journal_title:International journal of molecular sciences
pub_type: 杂志文章
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更新日期:2017-05-12 00:00:00
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journal_title:International journal of molecular sciences
pub_type: 杂志文章,评审
doi:10.3390/ijms20133164
更新日期:2019-06-28 00:00:00