Comparison of oral and buccal midazolam for pediatric dental sedation: a randomized, cross-over, clinical trial for efficacy, acceptance and safety.

Abstract:

OBJECTIVE:Providing a safe and efficient dental treatment for a young patient is a challenge for the dentist and the child. The purpose of this study was to investigate the effectiveness, safety and acceptability of buccal midazolam in dental pediatric patients and to compare it with oral Midazolam. METHODS:Eighteen uncooperative healthy children aged 2.5-6 years were randomized to each of buccal midazolam (0.3mg/kg) or oral midazolam (0.5mg/kg) at the first visit, the alternative has been used at the second visit in a cross-over manner. The study took place at pediatric dentistry clinic of Shahed University, Tehran, from November 2011 to June 2012. The patients' vital signs and behavioral scores were recorded. The patient, the operator and the observer were blinded to the applied medication. Post operatively, patients' and parents' satisfaction were assessed by Visual Analogue Score and a questionnaire respectively. The P-value was set at 0.05 for significance level. FINDINGS:There were no significant differences in physiologic factors in the medication groups at time 0, 10, 20, 30 minutes and discharge. There was also no significant difference between the two groups in behavioral parameters. The majority of parents rated both sedative agents as "effective" or "very effective" and their children mostly were without anxiety or with minor anxiety. CONCLUSION:Buccal midazolam may be safely and efficiently used in sedation of pediatric dental patients.

journal_name

Iran J Pediatr

authors

Tavassoli-Hojjati S Dds MSc,Mehran M Dds MSc,Haghgoo R Dds MSc,Tohid-Rahbari M Dds MSc,Ahmadi R Dds MSc

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

198-206

issue

2

eissn

2008-2142

issn

2008-2150

journal_volume

24

pub_type

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