Abstract:
PURPOSE:To assess the agreement between a Scheimpflug camera (Pentacam) and a combined Placido-optical coherence tomography device (Visante OMNI) in measuring corneal curvature, thickness and elevation values in normal and keratoconic eyes. METHODS:Corneal measurements of 110 normal eyes (one eye per subject) and 70 keratoconic eyes were obtained from both devices and compared. Agreement was determined using the Bland-Altman analysis 95% limits of agreement (LoA). RESULTS:The Pentacam measured significantly greater keratometry readings in the flattest (K1) and steepest meridians (K2) in normal and keratoconic eyes. The 95% LoA in normal eyes were -0.32 to 0.59 dioptres (D) (K1) and -0.41 to 0.74 D (K2). In keratoconic eyes, the 95% LoA were -1.35 to 1.92 D (K1) and -1.38 to 1.99 D (K2). The Pentacam recorded significantly higher central corneal thickness (CCT) values in both groups of eyes. The 95% LoA were -4.31 to 39.89 microns (μ) and -12.92 to 41.35 μ in normal and keratoconic eyes, respectively. Pentacam anterior and posterior corneal elevations were significantly greater in both groups of eyes. The devices demonstrated excellent repeatability and reproducibility for corneal curvature and thickness but not elevation measurements. CONCLUSIONS:The Pentacam measured significantly greater corneal curvature, thickness and elevation values compared to the Visante OMNI in normal and keratoconic eyes. The devices agree moderately for anterior corneal elevations in normal eyes and do not appear to be interchangeable for corneal measurements in clinical practice.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Viswanathan D,Kumar NL,Males JJ,Graham SLdoi
10.1111/aos.12622subject
Has Abstractpub_date
2015-09-01 00:00:00pages
e488-94issue
6eissn
1755-375Xissn
1755-3768journal_volume
93pub_type
杂志文章abstract:BACKGROUND/AIMS:The mitotic count of uveal melanomas correlates with the risk of metastatic death, but with haematoxylin and eosin (H&E)-stained sections, it can be difficult to identify mitotic figures (MF) reliably. We investigated whether this measurement could be enhanced by immunohistochemistry, using the mitosis-...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01769.x
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:To analyse intraocular cytokine levels and prevalence of intraocular antiretinal antibodies (ARAs) in patients with retinitis pigmentosa (RP), age-related macular degeneration (AMD), glaucoma and cataract, and correlate the results to clinical manifestations. METHODS:We collected intraocular fluid samples from...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13899
更新日期:2019-03-01 00:00:00
abstract::Topically applied carbonic anhydrase inhibitors (CAIs) in eye drop solutions are commonly used to treat glaucoma. However, local eye irritation and multiple daily administrations may hamper their clinical usefulness. Aqueous eye drop formulations that improve their topical bioavailability and reduce their eye irritati...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2011.02299.x
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:Central retinal vein occlusion (CRVO) entails retinal hypoxia that often causes visual impairment. It has been shown that oxygen saturation in larger retinal vessels correlates with the visual acuity at the time of diagnosis of CRVO but has no predictive value for the visual outcome in patients treated with ant...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14744
更新日期:2021-01-09 00:00:00
abstract::Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.12529
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:To evaluate a pro re nata administration of Ozurdex® implant versus a single administration for treating diabetic macular oedema (DME). METHODS:This exploratory study is designed as a comparative, multicentre, randomized study with a follow-up of 6 months. Patients with DME were assigned to treatment at baseli...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/aos.13395
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:To determine the myopia prevalence in Hong Kong Chinese children and their parents. METHODS:It was a population-based cross-sectional study. A total of 4257 children aged 6-8 years, and 5880 parents were recruited in the Hong Kong Children Eye Study. Cycloplegic autorefraction was measured for children; and no...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14350
更新日期:2020-01-24 00:00:00
abstract:PURPOSE:We investigated the natural course of the intraretinal hyperreflective (IRH) sign after macular haemorrhage (MHE) absorption in eyes with pathologic myopia. METHODS:This prospective observational cohort study evaluated 28 patients with pathologic myopia and MHE. The eyes were categorized into IRH and non-IRH s...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14332
更新日期:2019-12-06 00:00:00
abstract:PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14717
更新日期:2021-01-02 00:00:00
abstract:PURPOSE:To explore the efficacy of selective laser trabeculoplasty (SLT) within eyes with exfoliative glaucoma and history of prior argon laser trabeculoplasty (ALT). METHODS:A single-centre trial consisting of 47 patients (47 eyes) with uncontrolled exfoliative glaucoma. The main outcome measure was intraocular press...
journal_title:Acta ophthalmologica
pub_type: 临床试验,杂志文章
doi:10.1111/aos.14136
更新日期:2020-02-01 00:00:00
abstract:PURPOSE: To evaluate the precision of techniques for measuring intraocular pressure (IOP) in corneas with presumably altered biomechanical properties. METHODS: Intraocular pressure was measured with a Goldmann applanation tonometer (GAT), ocular response analyzer (ORA) and dynamic contour tonometer (DCT) in 70 eyes....
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12137
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To evaluate the effect of intravitreal injections of triamcinolone acetonide (IVTA) combined with panretinal photocoagulation (PRP) on visual acuity (VA) and foveal thickness in patients with concomitant high-risk proliferative diabetic retinopathy (PDR) and clinically significant macular oedema (CSMO). METHOD...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1600-0420.2007.00940.x
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:To report the postoperative results after enucleation of using an acrylic orbital implant covered in donor sclera for implantation. METHODS:We retrospectively analysed the charts of patients who were enucleated between 2007 and 2011. Only patients who received an acrylic implant covered with donor sclera were ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12960
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Current fundus imaging in newborn babies requires mydriatics, eye specula and corneal contact. We propose that a scanning laser ophthalmoscope (SLO) allows ultra wide-field imaging with reduced stress for the child. METHODS:This prospective observational single centre study was conducted in Landspítali, Univer...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13453
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:Metrics that capture changes in the retinal microvascular structure are relevant in the context of cardiometabolic disease development. The microvascular topology is typically quantified using monofractals, although it obeys more complex multifractal rules. We study mono- and multifractals of the retinal microv...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14598
更新日期:2020-09-16 00:00:00
abstract:PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01526.x
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To study the relation between ambient environmental ultraviolet radiation exposure and lens fluorescence. METHODS:Non-invasive lens fluorometry measurements were compared in healthy Bolivian and Danish subjects. Background ultraviolet radiation was 4.5 times higher in Bolivia than in Denmark. RESULTS:No signi...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2008.01488.x
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To determine whether anthropomorphic measurements are associated with ocular and general parameters. METHODS:The population-based Beijing Eye Study, which included 4439 participants (age > 40 years) out of 5324 individuals invited to be examined in 2001, was repeated in 2006 with 3251 (73.2% of 4439, or 61.1% ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01734.x
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To evaluate the regenerating potential and the mechanisms through which the autologous serum derived from plasma rich in growth factors (s-PRGF) favours corneal wound healing in vitro and in vivo. METHODS:We compared the effect of various concentrations of s-PRGF versus fetal bovine serum (FBS) and control tre...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13371
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To provide a systematic review of the published studies pertaining to the lifestyle modification, dietary, nutritional and vitamins supplements for preventing occurrence or halting deterioration of age-related macular degeneration (AMD). METHODS:The literature searches from 1990 to December 2010 with following...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2011.02357.x
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma has been reported. We, therefore, investigated the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE in a cell culture model. METHODS:The e...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12990
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Tissue inhibitors of metalloproteinases (TIMPs) block the catalysis by matrix metalloproteinases (MMPs) and have additional biologic activities, including regulation of cell growth and differentiation, apoptosis, angiogenesis and oncogenesis. We investigated the expression levels of all the four human TIMPs and...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13451
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:This paper reviews current knowledge about the pathogenesis, clinical manifestations and treatment of lattice corneal dystrophy, gelsolin type (LCD2, Meretoja's syndrome). METHODS:Material is derived from literature searches, a case study of a Finnish patient living in Sweden, and interviews in Helsinki with P...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/j.1755-3768.2009.01686.x
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the rise in aqueous humour (AH) levels of levofloxacin after a specific perioperative pulsed topical drop regimen. METHODS:Thirty patients undergoing phacoemulsification surgery were administered two preoperative drops of levofloxacin 0.5%, 30 mins apart, and three pulsed drops ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1755-3768.2008.01358.x
更新日期:2009-03-01 00:00:00
abstract::In the time of Vesalius, knowledge of ocular anatomy was limited. The first description of the anatomy of the eye comes from Democrites, for whom the eye was surrounded by two 'coats', filled with a homogenous fluid. The optic nerve was hollow and the lens was considered to be a postmortem artefact. Until the 15th cen...
journal_title:Acta ophthalmologica
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1755-3768.2009.01679.x
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate changes in the anterior chamber depth (ACD) in primary open-angle glaucoma (POAG) patients during latanoprost therapy. METHODS:We carried out a prospective study in which we enrolled 66 newly diagnosed POAG patients treated with latanoprost 0.005% (group 1) and 50 ocular h...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01683.x
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To investigate flow area changes measured using optical coherence tomography angiography (OCTA; RTVue XR Avanti® ) in patients with retinitis pigmentosa (RP) with preserved visual acuity (VA). METHODS:This was an age- and refraction-matched case-control study. Consecutive patients with a best-corrected visual ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13680
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:To examine the public health impact of presbyopia regarding its effect on quality of life (QoL) and society in both the developed and developing worlds. METHODS:A database was created from articles found on PubMed, the Cochrane Library and Science Direct using the following search terms: presbyopia, QoL, accom...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.12308
更新日期:2014-09-01 00:00:00
abstract::Asteroid hyalosis is defined by the presence of white, snowball-like non-crystalline vitreous opacities that move with the vitreous and appear to be anchored to its matrix. Asteroid hyalosis commonly occurs in the absence of other identifiable ocular abnormalities and is usually an incidental finding. The vitreous opa...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,评审
doi:10.1111/aos.14465
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to assess the brain regions associated with impaired performance in a virtual, dynamic collision avoidance task, in a group of patients with homonymous visual field defects (HVFDs) because of unilateral vascular brain lesions. METHODS:Overall task performance was quantitatively assess...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02315.x
更新日期:2012-05-01 00:00:00