Abstract:
BACKGROUND:Tissue Doppler imaging (TDI) is a method that determines the tissue motion and velocity within the myocardium. AIMS:To characterize acute haemodialysis (HD)-induced changes in TDI-derived indices for patients that have end-stage renal disease (ESRD). STUDY DESIGN:Cross sectional study. METHODS:Conventional echocardiography and TDI methods were applied to study ESRD patients (n=58) before and after HD. Pulmonary venous flow, mitral inflow, and TDI signals of the lateral and septal mitral annulus were examined for the determination of altered left-ventricular diastolic filling parameters. Flow velocities from early- (E) and late-atrial (A) peak transmitral; peak pulmonary vein systolic (S) and diastolic (D); and myocardial peak systolic (Sm) and peak early (Em) and late (Am) diastolic mitral annular velocities were also assessed for changes. RESULTS:Transmitral E and A velocities and the E/A ratio decreased significantly after HD (p<0.001). Pulmonary vein S (p<0.001) and D (p<0.001) velocities decreased, and S/D ratios increased significantly (p=0.027). HD led to a reduction in septal Em (p<0.001), lateral Em (p=0.006), and Am (p<0.001) velocities. Contrary to the decreases in Em and Am, the Em/Am ratio remained unchanged. CONCLUSION:A single HD session was associated with an acute deterioration in the diastolic parameters. Since the Em/Am ratio remained unchanged, we conclude that this index is a relatively load-independent measure of diastolic function in HD patients.
journal_name
Balkan Med Jjournal_title
Balkan medical journalauthors
Sağ S,Yeşilbursa D,Yıldız A,Dilek K,Sentürk T,Serdar OA,Aydınlar Adoi
10.5152/balkanmedj.2014.13170subject
Has Abstractpub_date
2014-09-01 00:00:00pages
239-43issue
3eissn
2146-3123issn
2146-3131pii
bmj-31-3-239journal_volume
31pub_type
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