Decreased peripheral arterial volume distensibility in patients with branch retinal vein occlusion in comparison with normal subjects.

abstract：:Recent advances in microfluidic cell cultures enable the construction of in vitro human skin models that can be used for drug toxicity testing, disease study. However, current in vitro skin model have limitations to emulate real human skin due to the simplicity of model. In this paper, we describe the development of '...

journal_title：Scientific reports

authors： Wufuer M,Lee G,Hur W,Jeon B,Kim BJ,Choi TH,Lee S

更新日期：2016-11-21 00:00:00

abstract：:Human mediated transportation into novel habitats is a prerequisite for the establishment of non-native species that become invasive, so knowledge of common sources may allow prevention. The brown marmorated stink bug (BMSB, Halyomorpha halys) is an East Asian species now established across North America and Europe, t...

journal_title：Scientific reports

authors： Valentin RE,Nielsen AL,Wiman NG,Lee DH,Fonseca DM

更新日期：2017-08-29 00:00:00

abstract：:The extracellular matrix (ECM) impacts stem cell differentiation, but identifying formulations supportive of differentiation is challenging in 3D models. Prior efforts involving combinatorial ECM arrays seemed intuitively advantageous. We propose an alternative that suggests reducing sample size and technological burd...

journal_title：Scientific reports

authors： Jung JP,Hu D,Domian IJ,Ogle BM

更新日期：2015-12-21 00:00:00

abstract：:The fine-tuning of gene expression contributes to both basic science and applications. Here, we develop a novel gene expression technology termed CRITGI (CRISPR/Transposon gene integration). CRITGI uses CRISPR/Cas9 to integrate multiple copies of the plasmid pTy1 into Ty1 loci, budding yeast retrotransposons. The pTy1...

journal_title：Scientific reports

authors： Hanasaki M,Masumoto H

更新日期：2019-10-25 00:00:00

abstract：:Motility dysfunction is present not only during bowel obstruction (BO), but after obstruction is resolved. Previous studies found that lumen distension associated mechano-transcription of COX-2 and production of PGE2 in gut smooth muscle cells (SMC) account for motility dysfunction during obstruction. We hypothesized ...

journal_title：Scientific reports

authors： Lin YM,Fu Y,Hegde S,Tang Y,Radhakrishnan R,Shi XZ

更新日期：2018-06-11 00:00:00

abstract：:Sublingual immunization is emerging as an alternative to nasal immunization and induction of mucosal IgA responses. Using Bacillus anthracis edema toxin (EdTx) as an adjuvant, we previously showed that innate responses triggered after sublingual immunization could limit generation of IgA responses. We tested whether c...

journal_title：Scientific reports

authors： Rowe JC,Attia Z,Kim E,Cormet-Boyaka E,Boyaka PN

更新日期：2019-01-24 00:00:00

abstract：:Scanning micro-mirror actuators are silicon-based oscillatory micro-electro-mechanical systems (MEMS). They enable laser distance measurements for automotive LIDAR applications as well as projection modules for the consumer market. For MEMS applications, the geometric structure is typically designed to serve a number ...

journal_title：Scientific reports

authors： Nabholz U,Schatz F,Mehner JE,Degenfeld-Schonburg P

更新日期：2019-03-08 00:00:00

abstract：:The human hepatoma-derived growth factor (HDGF), containing the chromatin-associated N-terminal PWWP domain capable of binding the SMYD1 promoter, participates in various cellular processes and is involved in human cancers. We report the first crystal structures of the human HDGF PWWP domain (residues 1-100) in a comp...

journal_title：Scientific reports

authors： Chen LY,Huang YC,Huang ST,Hsieh YC,Guan HH,Chen NC,Chuankhayan P,Yoshimura M,Tai MH,Chen CJ

更新日期：2018-01-10 00:00:00

abstract：:The North Sea is one of the most extensively studied marine regions of the world. Hence, large amounts of molecular data for species identification are available in public repositories, and expectations to find numerous new species in this well-known region are rather low. However, molecular reference data for harpact...

journal_title：Scientific reports

authors： Rossel S,Martínez Arbizu P

更新日期：2019-06-24 00:00:00

abstract：:The conservation of plant and animal genetic heritage is not a purpose in itself, but it represents the sine qua non condition for practicing a sustainable agriculture and to ensure nutrition and food security on long-term. Our research focused on identifying the areas with the richest genetic diversity of vegetables ...

journal_title：Scientific reports

authors： Maxim A,Străjeru S,Albu C,Sandor M,Mihalescu L,Pauliuc SE

更新日期：2020-10-28 00:00:00

abstract：:GABAergic and glutamatergic dysfunction in the dorsolateral prefrontal cortex (DLPFC) are thought to be the core pathophysiological mechanisms of schizophrenia. Recently, we have established a method to index these functions from the DLPFC using the paired transcranial magnetic stimulation (TMS) paradigms of short int...

journal_title：Scientific reports

authors： Noda Y,Barr MS,Zomorrodi R,Cash RFH,Farzan F,Rajji TK,Chen R,Daskalakis ZJ,Blumberger DM

更新日期：2017-12-06 00:00:00

abstract：:Muscle specific receptor tyrosine kinase (MuSK) is an essential postsynaptic transmembrane molecule that mediates clustering of acetylcholine receptors (AChR). MUSK exon 10 is alternatively skipped in human, but not in mouse. Skipping of this exon disrupts a cysteine-rich region (Fz-CRD), which is essential for Wnt-me...

journal_title：Scientific reports

authors： Nasrin F,Rahman MA,Masuda A,Ohe K,Takeda J,Ohno K

更新日期：2014-10-30 00:00:00

abstract：:The current assessment of corneal vascularisation (CV) relies on slit-lamp examination, which may be subjective. Dye-based angiographies, like indocyanine green angiography (ICGA), allows for good visualisation of anterior segment blood vessels. However, ICGA is invasive and can be associated with systemic adverse eff...

journal_title：Scientific reports

authors： Ong HS,Tey KY,Ke M,Tan B,Chua J,Schmetterer L,Mehta JS,Ang M

更新日期：2021-01-13 00:00:00

abstract：:Wound dressings with silver have been shown to be cytotoxic in vitro. However, the extrapolation of this cytotoxicity to clinical settings is unclear. We applied dressings with various forms of silver on porcine skin ex vivo and investigated silver penetration and DNA damage. We assessed antimicrobial efficacy, cytoto...

journal_title：Scientific reports

authors： Nešporová K,Pavlík V,Šafránková B,Vágnerová H,Odráška P,Žídek O,Císařová N,Skoroplyas S,Kubala L,Velebný V

更新日期：2020-09-16 00:00:00

abstract：:Iron (Fe) and manganese (Mn) are essential metals which, when scarce in the growth medium, are respectively taken up by the root high affinity transporters IRT1 and NRAMP1 in Arabidopsis thaliana. The molecular bases for low affinity transport however remained unknown. Since IRT1 and NRAMP1 have a broad range of subst...

journal_title：Scientific reports

authors： Castaings L,Caquot A,Loubet S,Curie C

更新日期：2016-11-16 00:00:00

abstract：:Transplantation of human bone marrow mesenchymal stromal cells (hBM-MSC) promotes functional recovery after stroke in animal models, but the mechanisms underlying these effects remain incompletely understood. We tested the efficacy of Good Manufacturing Practices (GMP) compliant hBM-MSC, injected intravenously 3.5 hou...

journal_title：Scientific reports

authors： Sammali E,Alia C,Vegliante G,Colombo V,Giordano N,Pischiutta F,Boncoraglio GB,Barilani M,Lazzari L,Caleo M,De Simoni MG,Gaipa G,Citerio G,Zanier ER

更新日期：2017-07-31 00:00:00

abstract：:It is challenging to create artificial catalysts that approach enzymes with regard to catalytic efficiency and selectivity. The enantioselective catalysis ranks the privileged characteristic of enzymatic transformations. Here, we report two pyridine-linked bis(β-cyclodextrin) (bisCD) copper(II) complexes that enantios...

journal_title：Scientific reports

authors： Xue SS,Zhao M,Ke ZF,Cheng BC,Su H,Cao Q,Cao ZK,Wang J,Ji LN,Mao ZW

更新日期：2016-02-26 00:00:00

abstract：:Monocytes/macrophages have been found to be an important component of colitis. However, the key chemokine that initiates the CCR2+ monocytes migration from circulation to colitis tissue remains to be undiscovered. PC3-secreted microprotein (PSMP) is a novel chemokine whose receptor is CCR2. The physiological and patho...

journal_title：Scientific reports

authors： Pei X,Zheng D,She S,Ma J,Guo C,Mo X,Zhang Y,Song Q,Zhang Y,Ma D,Wang Y

更新日期：2017-07-11 00:00:00

abstract：:Application of PCR to multiplexing assays is not trivial; it requires multiple fluorescent labels for amplicon detection and sophisticated software for data interpretation. Alternative PCR-free methods exploiting new concepts in nanotechnology exhibit high sensitivities but require multiple labeling and/or amplificati...

journal_title：Scientific reports

authors： Papadakis G,Tsortos A,Kordas A,Tiniakou I,Morou E,Vontas J,Kardassis D,Gizeli E

更新日期：2013-01-01 00:00:00

abstract：:Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functionally linked to alterations in glutamate levels. Despite the well-documented eff...

journal_title：Scientific reports

authors： Jones B,Balasubramaniam M,Lebowitz JJ,Taylor A,Villalta F,Khoshbouei H,Grueter C,Grueter B,Dash C,Pandhare J

更新日期：2021-01-14 00:00:00

abstract：:In this work, we experimentally investigate near-field capacitive coupling between a pair of single-gap split ring resonators (SRRs) in a terahertz metamaterial. The unit cell of our design comprises of two coupled SRRs with the split gaps facing each other. The coupling between two SRRs is examined by changing the ga...

journal_title：Scientific reports

authors： Rao SJM,Srivastava YK,Kumar G,Roy Chowdhury D

更新日期：2018-11-13 00:00:00

abstract：:Cellular therapies for liver diseases and in vitro models for drug testing both require functional human hepatocytes (Hum-H), which have unfortunately been limited due to the paucity of donor liver tissues. Human pluripotent stem cells (hPSCs) represent a promising and potentially unlimited cell source to derive Hum-H...

journal_title：Scientific reports

authors： Song W,Lu YC,Frankel AS,An D,Schwartz RE,Ma M

更新日期：2015-11-23 00:00:00

abstract：:Warburg effect or aerobic glycolysis provides selective growth advantage to aggressive cancers. However, targeting oncogenic regulators of Warburg effect has always been challenging owing to the wide spectrum of roles of these molecules in multitude of cells. In this study, we present ADP-dependent glucokinase (ADPGK)...

journal_title：Scientific reports

authors： Tandon A,Birkenhagen J,Nagalla D,Kölker S,Sauer SW

更新日期：2020-08-12 00:00:00

abstract：:Perovskite LaFeO3/montmorillonite nanocomposites (LaFeO3/MMT) have been successfully prepared via assembling LaFeO3 nanoparticles on the surface of montmorillonite with citric acid assisted sol-gel method. The results indicated that the uniform LaFeO3 nanoparticles were densely deposited onto the surface of montmorill...

journal_title：Scientific reports

authors： Peng K,Fu L,Yang H,Ouyang J

更新日期：2016-01-18 00:00:00

abstract：:Genome-wide association studies (GWAS) have uncovered numerous variants associated with body mass index (BMI), waist circumference, and waist-to-hip ratio. Our study aims to investigate how these variants are linked to fat distribution. We genotyped 56 validated variants of BMI, waist circumference, and waist-to-hip r...

journal_title：Scientific reports

authors： Wang T,Ma X,Peng D,Zhang R,Sun X,Chen M,Yan J,Wang S,Yan D,He Z,Jiang F,Bao Y,Hu C,Jia W

更新日期：2016-02-05 00:00:00

abstract：:In response to environmental and nutrient stress, adipose tissues must establish a new homeostatic state. Here we show that cold exposure of obese mice triggers an adaptive tissue remodeling in visceral adipose tissue (VAT) that involves extracellular matrix deposition, angiogenesis, sympathetic innervation, and adipo...

journal_title：Scientific reports

authors： Chang JC,Durinck S,Chen MZ,Martinez-Martin N,Zhang JA,Lehoux I,Li H,Lin M,Wu J,Bainbridge TW,Ernst JA,Ramani SR,Paduchuri S,Kates L,Solon M,Buechler MB,Castiglioni A,Thai M,Breart B,Modrusan Z,Peterson AS,Turley

更新日期：2019-06-20 00:00:00

abstract：:Meromictic lakes are useful biogeochemical models because of their stratified chemical gradients and separation of redox reactions down the water column. Perennially ice-covered meromictic lakes are particularly stable, with long term constancy in their density profiles. Here we sampled Lake A, a deep meromictic lake ...

journal_title：Scientific reports

authors： Comeau AM,Harding T,Galand PE,Vincent WF,Lovejoy C

更新日期：2012-01-01 00:00:00

abstract：:The search for green and sustainable modification method to produce durable bamboo materials remains a challenge in industry. Here, heat treatment in tung oil at 100-200 °C was employed to modify bamboo materials. Oil permeation and distribution in the structure of bamboo samples during heat treatment were explored. T...

journal_title：Scientific reports

authors： Tang T,Zhang B,Liu X,Wang W,Chen X,Fei B

更新日期：2019-09-06 00:00:00

abstract：:The graphdiyne (GD), a carbon allotrope with a 2D structure comprising benzene rings and carbon-carbon triple bonds, can be synthesized through cross-coupling on the surface of copper foil. The key problem is in understanding the dependence of layers number and properties, however, the controlled growth of the layers ...

journal_title：Scientific reports

authors： Qian X,Liu H,Huang C,Chen S,Zhang L,Li Y,Wang J,Li Y

更新日期：2015-01-13 00:00:00

abstract：:Postsynaptic density protein-95 (PSD-95) is a major regulator in the maturation of excitatory synapses by interacting and trafficking N-methyl-D-aspartic acid receptors (NMDAR) and α-amino-3-hydroxy-5-methyl-4-isox-azoleproprionic acid receptors (AMPAR) to the postsynaptic membrane. PSD-95 disruption has recently been...

journal_title：Scientific reports

authors： Coley AA,Gao WJ

更新日期：2019-07-01 00:00:00