Synthesis and anti-tubercular activity of 3-substituted benzo[b]thiophene-1,1-dioxides.

abstract：:The objectives of this experiment were to determine the effects of graded dietary lead (Pb) concentrations on body weight and Pb concentrations in blood, hair, soft tissues, and urine from pigs and to generate equations for estimating daily Pb intake. Sixteen barrows with initial body weight 36.3 kg (standard deviatio...

journal_title：PeerJ

authors： Reddy KE,Park KR,Lee SD,Yoo JH,Son AR,Lee HJ

更新日期：2017-11-01 00:00:00

abstract：:The incorporation of feedback into a person's body schema is well established. The crossmodal congruency task (CCT) is used to objectively quantify incorporation without being susceptible to experimenter biases. This visual-tactile interference task is used to calculate the crossmodal congruency effect (CCE) score as ...

journal_title：PeerJ

authors： Blustein D,Gill S,Wilson A,Sensinger J

更新日期：2019-05-22 00:00:00

abstract：:Analysis of calcium sparks in cardiomyocytes can provide valuable information about functional changes of calcium handling in health and disease. As a part of the calcium sparks analysis, sparks detection and characterization is necessary. Here, we describe a new open-source platform for automatic calcium sparks detec...

journal_title：PeerJ

authors： Laasmaa M,Karro N,Birkedal R,Vendelin M

更新日期：2019-03-29 00:00:00

abstract：:Background. Two non-tuberculous mycobacterial strains, UM_3 and UM_11, were isolated from the trunk wash of captive elephants in Malaysia. As they appeared to be identical phenotypes, they were investigated further by conventional and whole genome sequence-based methods of strain differentiation. Methods. Multiphasic ...

journal_title：PeerJ

authors： Chan KG,Loke MF,Ong BL,Wong YL,Hong KW,Tan KH,Kaur S,Ng HF,Abdul Razak M,Ngeow YF

更新日期：2015-11-10 00:00:00

abstract：:Four species of true crocodile (genus Crocodylus) have been described from the Americas. Three of these crocodile species exhibit non-overlapping distributions-Crocodylus intermedius in South America, C. moreletii along the Caribbean coast of Mesoamerica, and C. rhombifer confined to Cuba. The fourth, C. acutus, is na...

journal_title：PeerJ

authors： Milián-García Y,Russello MA,Castellanos-Labarcena J,Cichon M,Kumar V,Espinosa G,Rossi N,Mazzotti F,Hekkala E,Amato G,Janke A

更新日期：2018-11-12 00:00:00

abstract：:Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of inflammation and angiogenesis in adipose tissue. We have already repo...

journal_title：PeerJ

authors： Soumya SJ,Binu S,Helen A,Reddanna P,Sudhakaran PR

更新日期：2014-10-21 00:00:00

abstract：:Here we present the first two complete plastid genomes for Brunelliaceae, a Neotropical family with a single genus, Brunellia. We surveyed the entire plastid genome in order to find variable cpDNA regions for further phylogenetic analyses across the family. We sampled morphologically different species, B. antioquensis...

journal_title：PeerJ

authors： Valencia-D J,Murillo-A J,Orozco CI,Parra-O C,Neubig KM

更新日期：2020-01-28 00:00:00

abstract：:Rhodioloside, the main effective constituent of Rhodiola rosea, demonstrates antiaging and antioxidative stress functions and inhibits calcium overloading in cells. These functions imply that rhodioloside may exert protective effects on hippocampal neurons after total cerebral ischemia/reperfusion injury. In this stud...

journal_title：PeerJ

authors： Zhang Y,Guo X,Wang G,Liu J,Liang P,Wang H,Zhu C,Wu Q

更新日期：2020-11-09 00:00:00

abstract：Background:Sexual development in Flammulina velutipes is controlled by two different mating type loci (HD and PR). The HD locus contains homeodomain (Hd) genes on two separate HD subloci: HD-a and HD-b. While the functionality of the HD-b sublocus has been largely confirmed, the status and content of the HD-a sublocus ...

journal_title：PeerJ

authors： Wang W,Mukhtar I,Chou T,Jiang S,Liu X,van Peer AF,Xie B

更新日期：2019-02-22 00:00:00

abstract：Background:The highest rate of cancer-related deaths worldwide is from lung adenocarcinoma (LUAD) annually. Metabolism was associated with tumorigenesis and cancer development. Metabolic-related genes may be important biomarkers and metabolic therapeutic targets for LUAD. Materials and Methods:In this study, the glean...

journal_title：PeerJ

authors： Zhao Z,He B,Cai Q,Zhang P,Peng X,Zhang Y,Xie H,Wang X

更新日期：2020-09-24 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most heterogeneous malignant cancers with no effective targets and treatments. However, the molecular pathogenesis of HCC remains largely uncertain. The aims of our study were to find crucial genes involved in HCC through multidimensional methods and revealed potential mole...

journal_title：PeerJ

authors： Liu ZK,Zhang RY,Yong YL,Zhang ZY,Li C,Chen ZN,Bian H

更新日期：2019-08-08 00:00:00

abstract：INTRODUCTION:There is much literature devoted to the problem of drug resistance and decreased susceptibility of fungi to commonly used antifungals. AIM:To analyze drug susceptibility of Candida albicans and non-Candida albicans strains isolated from the hands of people without any symptoms of disease over a 16-year pe...

journal_title：PeerJ

authors： Łukaszuk C,Krajewska-Kułak E,Kułak W

更新日期：2017-02-23 00:00:00

abstract：:Knowledge on the precise identification of fish resources is critical for sustainable fisheries management. This study employs the DNA barcoding approach to generate a molecular taxonomic catalogue of commercially important reef fishes in the waters of Weh Island (Aceh Province), the most northerly inhabited island in...

journal_title：PeerJ

authors： Fadli N,Mohd Nor SA,Othman AS,Sofyan H,Muchlisin ZA

更新日期：2020-08-05 00:00:00

abstract：:Background. Physical activity is important for children's physical, mental, and social well-being. Outdoor active play is an important yet unstudied domain of children's physical activity. The objective of this study was to determine if parental encouragement is associated with the frequency that children engage in ou...

journal_title：PeerJ

authors： Ferrao T,Janssen I

更新日期：2015-11-30 00:00:00

abstract：:Pantoea stewartii subsp. stewartii is a bacterial phytopathogen that causes Stewart's wilt disease in corn. It uses quorum sensing to regulate expression of some genes involved in virulence in a cell density-dependent manner as the bacterial population grows from small numbers at the initial infection site in the leaf...

journal_title：PeerJ

authors： Packard H,Kernell Burke A,Jensen RV,Stevens AM

更新日期：2017-04-27 00:00:00

abstract：:The whitefly Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is a cryptic species complex, including members that are pests of global importance. This study presents a screening of B. tabaci species in China for infection by the primary endosymbiont, Portiera aleyrodidarum, and two secondary endosymbionts, Arsenop...

journal_title：PeerJ

authors： Tang XT,Cai L,Shen Y,Du YZ

更新日期：2018-08-29 00:00:00

abstract：:Background. Physical, visual, chemical, and auditory cues signalling fighting ability have independently evolved in many animal taxa as a means to resolve conflicts without escalating to physical aggression. Facial width-to-height ratio (fWHR, i.e., the relative width to height of the face) has been associated with do...

journal_title：PeerJ

authors： Borgi M,Majolo B

更新日期：2016-03-21 00:00:00

abstract：Background:Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and maturation in the developing cortex. However, at higher concentrations AEA also engages vanilloid receptor TRPV1, usually with opposed consequences o...

journal_title：PeerJ

authors： Diniz CRAF,Biojone C,Joca SRL,Rantamäki T,Castrén E,Guimarães FS,Casarotto PC

更新日期：2019-02-21 00:00:00

abstract：:Recent improvements in next-generation sequencing (NGS) technologies can facilitate the obtainment of mitochondrial genomes. However, it is not clear whether NGS could be effectively used to reconstruct the mitogenome with high gene rearrangement. These high rearrangements would cause amplification failure, and/or ass...

journal_title：PeerJ

authors： Yuan S,Xia Y,Zheng Y,Zeng X

更新日期：2016-12-15 00:00:00

abstract：:Mitochondria are small, energy-producing structures vital to the energy needs of the body. Genetic mutations cause mitochondria to fail to produce the energy needed by cells and organs which can cause severe disease and death. These genetic mutations are likely to be in the mitochondrial DNA (mtDNA), or possibly in th...

journal_title：PeerJ

authors： Ahuja AS

更新日期：2018-05-21 00:00:00

abstract：:Background. India accounts for 24% to all under-five mortality in the world. Residence in rural area, poverty and low levels of mother's education are known confounders of under-five mortality. Since two-thirds of India's population lives in rural areas, mothers employed in agriculture present a particularly vulnerabl...

journal_title：PeerJ

authors： Singh R,Tripathi V

更新日期：2015-01-08 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00

abstract：:Vitellogenin has been proposed to regulate division of labor and social organization in social insects. The red imported fire ant (Solenopsis invicta) harbors four distinct, adjacent vitellogenin genes (Vg1, Vg2, Vg3, and Vg4). Contrary to honey bees that have a single Vg ortholog as well as potentially fertile nurses...

journal_title：PeerJ

authors： Hawkings C,Tamborindeguy C

更新日期：2018-05-28 00:00:00

abstract：Background:Plums are a kind of stone fruit, a category that includes peaches, cherries, apricots, and almonds. In Korea, Japanese plum trees are usually cultivated as they best suit the climate. To date, there have been few studies in Korea on viruses infecting plum trees compared to those infecting peach trees. Metho...

journal_title：PeerJ

authors： Jo Y,Choi H,Lian S,Cho JK,Chu H,Cho WK

更新日期：2020-07-29 00:00:00

abstract：Background:The table tennis serve involves complex spatial movements combined with biomechanial characteristics. Although the differences in lower-limb biomechanial characteristics to a great extent influence the translational and spinning velocity of the ball when using the different styles of table tennis serve, few ...

journal_title：PeerJ

authors： Yu C,Shao S,Baker JS,Gu Y

更新日期：2018-06-01 00:00:00

abstract：:The decline in the number of hours Americans spend outdoors, exacerbated by urbanization, has affected people's familiarity with local wildlife. This is concerning to conservationists, as people tend to care about and invest in what they know. Children represent the future supporters of conservation, such that their k...

journal_title：PeerJ

authors： Schuttler SG,Stevenson K,Kays R,Dunn RR

更新日期：2019-07-23 00:00:00

abstract：BACKGROUND:Cloud forests, characterized by a persistent, frequent or seasonal low-level cloud cover and fragmented distribution, are one of the most threatened habitats, especially in the Neotropics. Tree ferns are among the most conspicuous elements in these forests, and ferns are restricted to regions in which minimu...

journal_title：PeerJ

authors： Sosa V,Ornelas JF,Ramírez-Barahona S,Gándara E

更新日期：2016-11-16 00:00:00

abstract：:Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions. Because of the complex nature of these communities, existing metagenome binning methods often miss a large...

journal_title：PeerJ

authors： Kang DD,Froula J,Egan R,Wang Z

更新日期：2015-08-27 00:00:00

abstract：:Allium tenuissimum L. is a widely distributed perennial herbaceous species in temperate and desert steppes. Relative to other wild Allium species, it produces unique sweet flavors, more biomass in arid and cold environments, and has generated greater interest for crop production. Successful crop establishment, however...

journal_title：PeerJ

authors： Xiao H,Yang H,Monaco T,Song Q,Rong Y

更新日期：2020-04-07 00:00:00

abstract：:Artifacts removal and rhythms extraction from electroencephalography (EEG) signals are important for portable and wearable EEG recording devices. Incorporating a novel grouping rule, we proposed an adaptive singular spectrum analysis (SSA) method for artifacts removal and rhythms extraction. Based on the EEG signal am...

journal_title：PeerJ

authors： Hu H,Guo S,Liu R,Wang P

更新日期：2017-06-28 00:00:00